Engineering Commons^™

Characterization And Design Of A Completely Parameterizable Vhdl Digital Single Sideband Modulator Circuit For Quick Implementation In Fpga Or Asic Electronic Warfare Platforms, Harold Scott Axtell

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In this work we present the design and characterization of a parameterizable Digital Single Sideband Modulator (DSSM) circuit for use with a Digital Radio Frequency Memory (DRFM) or other signal processing circuits. Field Programmable Gate Arrays (FPGAs) can be used as a prototyping platform for quickly verifying and hardware testing a digital circuit or system. FPGAs can also be used as an implementation platform for a digital circuit or system. A main advantage of FPGAs over that of an Application Specific Integrated Circuit (ASIC) is that it can be quickly (and often dynamically) reprogrammed; whereas an ASIC can take months …

Impact Of Induced Defects On Rotor Life Assessment, Ashley Winfield Whitney-Rawls

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There is an economic need to reduce the conservatisms of current lifing methods and extend component life. Extending component usage increases the probability of failure during operation. Therefore, the risk of continued service must be quantified before life extension concepts can successfully be implemented. The current FAA approved software for the certification of new rotor designs, only accounts for defects present prior to service. Defects due to the handling of components during inspection and material fatigue will induce defects during service and need to be included in any analysis of component life extension. Component life extension analysis of an Inconel …

Fabrication And Analysis Of Compositionally Graded Functional Layers For Solid Oxide Fuel Cells, Jared Ray Mccoppin

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Solid Oxide Fuel Cell (SOFC) structures must be optimized for high performance, increased life, and low cost. Fabrication methods are an area of research interest in bringing down the total cost of SOFCs, and can also impact cell life and performance. Graded functional layers have been shown to enhance cell performance, but current fabrication methods require multiple fabrication steps. This thesis describes a novel fabrication method capable of compositional gradation of functional layers for SOFCs. Using colloidal spray deposition technology, a controlled co-deposition strategy was utilized to fabricate SOFC's with compositionally graded cathode and anode functional layers (CGCFL/CGAFL). In this …

High Frequency Vco And Frequency Divider In Vlsi 90nm Technology, Paesol Veerakitti

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A Voltage Controlled Oscillator (VCO) is essentially a tunable frequency generator. A VCO is used as a part in PLL system which is a system that generates a stable oscillating signal. As the digital electronic industry demands an ever increasing performance in speed, VCO's are required to create higher frequency signals. However, the phase noise performance of a VCO decreases as the operating frequency gets higher. The LC VCO is developed in this thesis to be used in with a tunable frequency divider as a part of a PLL system. The LC VCO structure design takes the advantage of a …

Stochastic Mistuning Simulation Of Integrally Bladed Rotors Using Nominal And Non-Nominal Component Mode Synthesis Methods, Joseph A. Beck

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Mistuning prediction in integrally bladed rotors is often done with reduced order models that minimize computational expenses. A common model reduction technique used for mistuning applications is the component mode synthesis method. In this work, two modern component mode synthesis methods are used to generate mistuned response distributions that will be used to determine if the two methods are statistically indistinguishable. The first method, nominal mode approximation, assumes an airfoil geometric perturbation alters only the corresponding substructure modal stiffnesses while its mode shapes remain unaffected. The mistuned response is then predicted by a summation of the nominal modes. The second …

Development Of An Efficient Super-Resolution Image Reconstruction Algorithm For Implementation On A Hardware Platform, Pestak Thomas C.

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There is a growing demand from numerous commercial and military applications for images with ever-improving spatial resolution. However, there are resolution-limiting factors inherent in all imaging systems. Decreasing pixel sizes and/or increasing sensor arrays are not always viable. Super-Resolution (SR) Image Reconstruction is an image processing technique that restores a high-resolution (HR) image from a series of low-resolution (LR) images of a particular scene. Recently, there has been extensive research on robust SR algorithms used for post-processing. The goal of this thesis is to explore the current SR research and design computationally efficient SR algorithms for real-time processing based on …

Experimental Studies Of Turbulent Boundary Layers Over A Rough Forward-Facing Step And Its Coarse Scale Resolution Approximations, Huiying Ren

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High spatial resolution PIV experiments are performed in the x-y plane at two different spanwise positions to compare the turbulent boundary layers over smooth and rough forward-facing-steps as well as the rough step's two coarse scale-resolution approximations. The Reynolds number based on the step's mean height, Re_h, is 3450 and the ratio of the boundary layer thickness to the step's height is δ/h = 8. The roughness topography on the top surface of the rough step is replicated from a realistic turbine blade and is intrinsically three-dimensional and highly irregular. The surface topographies of the coarse scale-resolution …

Hard-Switching And Soft-Switching Two-Switch Flyback Pwm Dc-Dc Converters And Winding Loss Due To Harmonics In High-Frequency Transformers, Dakshina S. Murthy Bellur

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The flyback pulse-width modulated (PWM) DC-DC power converter is a very important circuit in switching mode power supply (SMPS) converters for low power applications. The main drawback of the conventional single-switch flyback converter is the high turn-off voltage stress suffered by the switch. The high voltage transients are caused by the resonant behavior of the transformer leakage inductance and the transistor output capacitance, resulting in ringing superimposed on the steady-state switch voltage level. This requires a transistor with higher voltage rating. However, a transistor with higher voltage rating has higher on-resistance causing higher conduction loss. The high voltage ringing also …

Visualization Of Complex Unsteady 3d Flow: Flowing Seed Points And Dynamically Evolving Seed Curves With Applications To Vortex Visualization In Cfd Simulations Of Ultra Low Reynolds Number Insect Flight, Christopher M. Koehler

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Three dimensional integration-based geometric visualization is a very powerful tool for analyzing flow phenomena in time dependent vector fields. Streamlines in particular have many perceptual benefits due to their ability to provide a snapshot of the vectors near key features of complex 3D flows at any instant in time. However, streamlines do not lend themselves well to animation. Subtle changes in the vector field at each time step lead to increasingly large changes between streamlines with the same seed point the longer they are integrated. Path lines, which show particle trajectories over time suffer from similar problems when attempting to …

Population Fit Threshold: Fully Automated Signal Map Generation For Baseline Correction In Nmr-Based Metabolomics, Daniel C. Homer

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Baseline correction of NMR-based metabolomic spectra is a key step in data processing to elucidate biomarkers of diseased and toxic states. Automated baseline correction methods often use human-selected parameters. Presented is a method for automated baseline correction using parameters selected from and without manipulation of the spectrum. The focus is on generating an accurate signal map based on the differentiating characteristics of baseline noise and signal. The presented method of signal map generation and baseline correction was developed and tested on 13C and 1H NMR spectra. The spectra were as simple as chemical standards containing less than 25 signal peaks …

Ab Initio Simulations Of Hydrogen And Lithium Adsorption On Silicene, Tim H. Osborn

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The energies and temperature-dependent dynamics of hydrogen and lithium chemisorption on a silicon nanosheet, called silicene, were studied using density functional theory and molecular-dynamics (MD) simulations. Silicene has a buckled honeycomb structure, and has been fabricated as suspended monolayer sheets and nanoribbons in recent experiments. We calculated the adsorption energies of hydrogen and lithium on silicene for different adsorption ratios between 3.1% and 100%. The studies will clarify the characteristics of these novel and promising nanomaterials, and pave the way for their applications.

For Hydrogen, the adsorption energy had a maximum of 3.01 eV/H for complete hydrogenation, and decreased by …

Charaterization Of Chlorpyrifos Toxicity On The Pancreatic Beta Cell Line Rinm5f, Zhongyu Yan

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Chlorpyrifos (CPF) is a well-known organophosphate (OP) insecticide that inhibits acetylcholinesterase (AChE). Organophosphates have been shown to induce hyperglycemia in both humans and animals that cannot be explained by AChE inhibition alone. Pancreatic β-cells are responsible for secreting insulin and playing a fundamental role in glucose homeostasis. The aim of this research was to investigate CPF toxicity on the insulin secreting β-cell line RINm5f (RIN). In the first part of this dissertation, we determined that cytotoxic concentrations of CPF between 50 µM and 200 µM induced a dose-dependent increase in RIN cell apoptotic and necrotic death (p<0.05). Lower doses, i.e., 5-25 µM did not induce apoptosis or necrosis. In further mechanistic studies, inhibitors of c-Jun N-terminal kinase (JNK) and P38 pathways, i.e., SP600125 and SB202190, successfully attenuated CPF-induced apoptosis (p<0.05), suggesting cell death is mediated by JNK and/or p38. In addition, N-Acetyl-L-cysteine (NAC), an antioxidant, inhibited apoptosis suggesting that oxidative stress is also involved in RIN cell death. In the second part of this dissertation, low dose CPF's effects on insulin synthesis and secretion was studied. Our results showed that RIN cells treated with CPF for 4 hr exhibited a dose-dependent decrease in insulin secretion in response to stimulation by 50 mM potassium (p<0.05). Insulin secretion stimulated by 25 mM glucose also showed significant decreases upon incubation with various doses of CPF (p<0.05). Insulin synthesis involves proteolytic cleavage of proinsulin at two specific sites. The enzymes responsible for promoting proinsulin cleavage, i.e, prohormone convertase (PC) 1/3 and 2 (PC2), contain a serine hydrolase catalytic triad, His-Asp-Ser, similar to AChE. CPF modification of PC enzymes similar to AChE, could potentially interrupt the conversion of proinsulin to insulin and disrupt insulin secretion. PC2 enzyme activity was significantly inhibited by CPF at concentrations as low as 10 µM (p<0.01). RIN cells, for the first time, were found to secrete proinsulin was through a constitutive instead of a regulated pathway. In summary, our results show that CPF not only exerts a direct cytotoxic effect at concentrations above 50 µM, but also significantly impairs insulin secretion at lower doses. Low dose CPF could potentially affect endocrine function in vivo by inhibiting the proinsulin processing enzyme PC2.

Extent And Effects Of Selection To Reduce Synthetic Cost Of Highly Expressed Proteins, Esley Marvin Heizer Jr

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Organisms that preferentially utilize less biosynthetically expensive amino acids in highly expressed genes exhibit metabolic efficiency. Exploration of this phenomenon has been limited to six prokaryotes.

I present a large scale analysis of metabolic efficiency in prokaryotic organisms and analysis of two eukaryotes (Saccharomyces cerevisiae and humans). Examination of 73 bacteria reveals the presence of metabolic efficiency in 66 organisms. The average correlation between amino acid biosynthetic cost and CAI scores in these organisms is -0.21. The seven organisms that did not exhibit metabolic efficiency are all Lactobacilli and highly auxotrophic. Saccharomyces cerevisiae exhibits significant trends between average amino acid …

Radio Frequency Controlled Stimulation Of Intracellular Gold Or Silver Nanoparticle Conjugates For Use As Potential Sensors Or Modulators Of Biological Function, Richard Craig Murdock

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The objective of this investigation was to further explore the ability of a radio frequency (RF) signal to interact with metal nanoparticles (NPs) for the purposes of remote stimulation or control of cellular processes. Gold and silver NPs have shown the ability to be heated by electromagnetic frequencies, especially for the purpose of deactivating abnormal cells. However, the heating of the NPs in these previous studies was constant and uncontrolled. For this study, our hypothesis was by investigating the RF heating characteristics of NPs and its impact on surface functionalizations, a remotely stimulated control mechanism can be developed at the …

Algorithmic Techniques Employed In The Quantification And Characterization Of Nuclear Magnetic Resonance Spectroscopic Data, Paul Edward Anderson

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Nuclear magnetic resonance (NMR) based metabolomics is a developing research field with broad applicability, including the identification of biomarkers associated with pathophysiologic changes, sample classification based on the mechanism of toxicity, and clinical diagnosis. Intrinsic to these applications is the need for statistical and computational techniques to facilitate the associated data analysis. Further, a typical 1H NMR spectrum of pure proteins, biofluids, or tissue may contain thousands of resonances (i.e., peaks), thus, a pure visual inspection is insufficient to fully utilize the spectral information.

Common practice within the NMR-based metabolomics community is to evaluate and validate novel algorithms on empirical …

A Human-Computer Integrated Approach Towards Content Based Image Retrieval, Phani Nandan Kidambi

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Digital photography technologies permit quick and easy uploading of any image to the web. Millions of images being are uploaded on the World Wide Web every day by a wide range of users. Most of the uploaded images are not readily accessible as they are not organized so as to allow efficient searching, retrieval, and ultimately browsing. Currently major commercial search engines utilize a process known as Annotation Based Image Retrieval (ABIR) to execute search requests focused on retrieving an image. Even though the information sought is an image, the ABIR technique primarily relies on textual information associated with an …

Design Of Hf Forward Transformer Including Harmonic Eddy Current Losses, Dhivya Ammanambakkam Nagarajan

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Pulse Width Modulated (PWM) Forward DC-DC converter is a buck-derived isolated power converter which is used extensively in low power to medium power applications. Satisfactory operation of the transformer utilized in forward converter plays a crucial role in the overall operation of the forward converter. Hence detailed analysis pertaining to design of forward transformer is important. The forward transformer is unique as the magnetizing inductance is not required to store magnetic energy. Additionally, the forward transformer has a tertiary winding, which is required to reset the core and to prevent core saturation. This adds to the complexity of design and …

Use Of Web-Based Lessons Of Statistical Concepts With Graphics And Animation To Enhance The Effectiveness Of Learning, Lavanya Pillala

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Statistics is of critical importance to engineers. However, many engineering students struggle to grasp the meaning of statistical concepts and the idiosyncrasies of statistical methodologies. Because of this problem, instructors of statistics are constantly searching for better ways to help students understand statistical concepts. The goal of this project is to design and develop web-based lessons that use graphics and animations to enhance the effectiveness of students' learning of statistical concepts.

Lessons of three important statistical concepts have been developed for this thesis - normal distribution, central limit theorem and confidence & tolerance intervals - following well-recognized instructional design development …

Evolution And Analysis Of Neuromorphic Flapping-Wing Flight Controllers, Sanjay Kumar Boddhu

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The control of insect-sized flapping-wing micro air vehicles is attracting increasing interest. Solution of the problem requires construction of a controller that is physically small, extremely power efficient, and capable. In addition, process variation in the creation of very small wings and armatures as well as the potential for accumulating damage and wear over the course of a vehicle's lifetime suggest that controllers be able to self-adapt to the specific and possibly changing nature of the vehicles in which they are embedded. Previous work with Evolvable Hardware Continuous Time Recurrent Neural Networks (CTRNNs) as applied to adaptive control of walking …

Hyperspectral Methods Of Determining Grit Application Density On Sandpaper, Lee A. Clark

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A low cost real time method of determining the density of grit applied to sandpaper does not currently exist. This thesis will explore three methods for determining grit density from digital image data. A means to characterize the application in terms of frequency by using direct cosine transform basis images will be explored. An RX detector algorithm to characterize the image background will be tested. A linear unmixing methodology will be developed that characterizes the proportion of glue and grit present in each hyperspectral pixel vector.

The History, Philosophy, And Practice Of Agent-Based Modeling And The Development Of The Conceptual Model For Simulation Diagram, Brian L. Heath

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This research advances ABM as a generic analysis tool such that ABM can reach its full potential as a revolution in modeling and simulation. To achieve this goal, the field of ABM is examined from many perspectives. The first perspectives examined are complex systems, the historical emergence of ABM, and philosophical issues related to ABM. These topics establish some clear foundations for the field across multiple disciplines. Next the current practice of ABM is investigated. Through a comprehensive 279 article survey some current deficiencies and opportunities in ABM are identified. Based on these opportunities, a new diagramming technique called the …

Characterization Of Internal Wake Generator At Low Reynolds Number With A Linear Cascade Of Low Pressure Turbine Blades, Chase A. Nessler

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Unsteady flow and its effects on the boundary layer of a low pressure turbine blade is complex in nature. The flow encountered in a low pressure turbine contains unstructured free-stream turbulence, as well as structured periodic perturbations caused by upstream vane row wake shedding. Researchers have shown that these conditions strongly influence turbine blade performance and boundary layer separation, especially at low Reynolds numbers. In order to simulate these realistic engine conditions and to study the effects of periodic unsteadiness, a moving bar wake generator has been designed and characterized for use in the Air Force Research Labs low speed …

A Novel Synergistic Diagnosis Methodology For Identifying Abnormalities In Wireless Capsule Endoscopy Videos, Alexandros Karargyris

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Wireless Capsule Endoscopy (WCE) is a new technology that allows medical personnel to view the gastrointestinal (GI) mucosa. It is a swallowable miniature capsule device the size of a pill that transmits thousands of screenshots of the digestive tract to a wearable receiver. When the procedure finishes the video is uploaded to a workstation for viewing. Capsule Endoscopy has been established as a tool to identify various gastrointestinal (GI) conditions, such as blood-based abnormalities, polyps, ulcers, Crohn's disease in the small intestine, where the classical endoscopy is not regularly used.

As of 2009 the market is dominated by Given Imaging …

Sulfur-Tolerant Catalyst For The Solid Oxide Fuel Cell, Bozeman Joe Frank Iii

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JP-8 fuel is easily accessible, transportable, and has hydrogen content essential to solid oxide fuel cell (SOFC) operation. However, this syngas has sulfur content which results in a poisonous hydrogen sulfide that degrades electrochemical activity and causes complete SOFC failure in some cases. The goal is to synthesize and verify a cost-effective, catalyst supported on cerium oxide that either stabilizes ionic conductivity in the presence of hydrogen sulfide and/or is highly sulfur-resistant. After thorough computational analysis, it was concluded that the platinum-copper skin catalyst was the most cost-effective, sulfur-resistant catalyst. Experimental synthesis of copper, platinum, and platinum-copper skin catalysts supported …

Design And Development Of A Wireless Data Acquisition System For Fall Detection, Anoop Hanchinamane Ramakrishna

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With the mortality rate of the elderly on the rise due to fall related incidents, fall detection has become an important entity in the geriatric health care sector. The study conducted in this thesis involved the design and development of a Wireless Data Acquisition System (WDAS) with Bluetooth capabilities interfaced to pulse width modulated gyroscopic sensors. Each sensor used has a reference output pulse width which changes when rotated about its sensitive axis.Part of the effort involves the design and development of two versions of printed circuit boards for the application. Each board includes a Parallax Propeller micro- controller in …

Uncertainty Quantification Of Residual Stresses Induced By Laser Peening Simulation, Hemanth Amarchinta

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Advanced mechanical surface enhancement techniques have been used successfully to increase the fatigue life of metallic components. These techniques impart deep compressive residual stresses into the component to counter potentially damage-inducing tensile stresses generated under service loading. Laser Peening (LP) is an advanced mechanical surface enhancement technique used predominantly in the aircraft industry. To reduce costs and make the technique available on a large-scale basis for industrial applications, simulation of the LP process is required. Accurate simulation of the LP process is a challenging task, because the process has many parameters such as laser spot size, pressure profile, and material …

High-Power Energy Scavenging For Portable Devices, Simon J. Tritschler

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Portable electronic devices and crafts such as unmanned aerial vehicles (UAV's) may benefit greatly from the ability to extract power from overhead distribution power lines on a temporary basis to power electronics or charge on-board batteries. However, most of the current literature on the subject of energy scavenging is focused on micropower and other small-scale applications. Several high-power energy scavenging methods are investigated here with an emphasis on relating physical sensor dimensions with output power. A novel power scavenging mechanism is introduced that shows excellent correlation between theoretical and experimental performance. In addition, a universal power supply is proposed which …

Relative Stability Of The Inner-Current Loop Of Peak Current-Mode Controlled Pwm Dc-Dc Converters In Ccm, Nisha Kondrath

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Current-mode control is a commonly adopted method of regulation for pulse-width modulated (PWM) dc-dc power converters in industry, but is not well understood. The advantages of current-mode control over the voltage-mode control include inherent overload and short circuit protection, faster response, line-noise rejection, and multiple converter paralleling. Current-mode controlled system consists of (1) an inner-current loop and (2) an outer-voltage loop, which sets the reference voltage to the inner loop. To ensure stable operation of the multi-loop converter, all the sequential loops in the circuit should be stable with sufficient degree of stability. The research in this dissertation is focused …

Fusion Of Video And Doppler Radar For Traffic Surveillance, Arunesh Roy

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Current Continuous Wave (CW) Doppler radar speed measurement systems lack the ability to distinguish multiple targets. Most systems can only identify the strongest (closest) target or the fastest target.

This dissertation is related to a fusion algorithm for a VIdeo-Doppler-radAR (Vidar) traffic surveillance system. The Vidar systems uses a robust matching algorithm which iteratively matches the information from a video camera and multiple Doppler radars corresponding to the same moving vehicle, and a stochastic algorithm which fuses the matched information from the video camera and Doppler radars to derive the vehicle velocity and angle information.

We use two heterogeneous sensors …

Understanding The Molecular Dynamics Of Ypel3 And Fhit Gene Expression, Kevin Daniel Kelley

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A comprehensive understanding of the molecular signaling pathways that regulate cell growth and proliferation is essential in the realization of new therapeutic options to facilitate early detection and eradication of malignancy. Understanding the transcriptional regulation of the YPEL3 and FHIT genes forms the basis of this dissertation. YPEL3, or Yippee-like 3, is a newly identified p53 target gene that inhibits tumor cell growth and is thus itself, a novel tumor suppressor gene. FHIT, or Fragile histidine triad, is a well known tumor suppressor gene and is regulated at the transcriptional level by another growth inhibitory protein, FOXO3a, a Forkhead box …