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Articles 1 - 7 of 7
Full-Text Articles in Engineering
The Effects Of Parkinson's On Fixational Stability, Erin L. Mallahan
The Effects Of Parkinson's On Fixational Stability, Erin L. Mallahan
Theses and Dissertations
Parkinson's disease (PD) is a progressive, neurological movement disorder. The stability of eye movements in PD is not well understood but many patients report difficulty doing tasks that require stabilized fixation and gaze. The ability to stabilize an image on the retina is critical is acquiring visual information. The purpose of this study was to compare the stability of fixational eye movements of PD patients to those of age-matched controls. Eye movements during simple fixation tasks were recorded from 66 subjects (ages 52 to 84), and 36 age-matched controls (ages 58-85). The absolute velocity of the fixational eye movements were …
Myocardial Perfusion Imaging With Rb-82 Pet, George Nittil Francis
Myocardial Perfusion Imaging With Rb-82 Pet, George Nittil Francis
Theses and Dissertations
Myocardial perfusion imaging (MPI) is an effective technique used to study the left ventricular ejection function (LVEF), myocardial perfusion, wall motion, and wall thickening. Positron emission tomography (PET) and single photon emission computed tomography (SPECT) are two modalities that can be used to quantify the left global and regional perfusion at rest and stress. While PET and SPECT rely on similar principles to produce images, important differences in instrumentation and experimental applications are dictated by inherent differences in their respective physics of radioactive decay. With a sensitivity > 90% in combination with a high specificity, PET is today the best available …
The Extraction Of Type Ii Collagen And The Electrospinning Of Nano-Fibrous Scaffolds, Danielle Careen Knapp
The Extraction Of Type Ii Collagen And The Electrospinning Of Nano-Fibrous Scaffolds, Danielle Careen Knapp
Theses and Dissertations
Articular cartilage lining joints, such as in the knee, functions to reduce friction and absorb shock. Collagen type II is the largest constituent in the extracellular matrix of articular cartilage and its restoration is of the highest interest to tissue engineers. Cartilage has little ability to naturally regenerate due to the absence of vascularity and the inability of the chondrocytes to proliferate at a high rate. It would be ideal to create a mimicking extracellular matrix/scaffold from type II collagen that could possibly be used to replace damaged articular cartilage that has the same function and morphology. Three different groups …
Iterative Methods For The Reconstruction Of Tomographic Images With Unconventional Source-Detector Configurations, Abey Mukkananchery
Iterative Methods For The Reconstruction Of Tomographic Images With Unconventional Source-Detector Configurations, Abey Mukkananchery
Theses and Dissertations
X-ray computed tomography (CT) holds a critical role in current medical practice for the evaluation of patients, particularly in the emergency department and intensive care units. Expensive high resolution stationary scanners are available in radiology departments of most hospitals. In many situations however, a small, inexpensive, portable CT unit would be of significant value. Several mobile or miniature CT scanners are available, but none of these systems have the range, flexibility or overall physical characteristics of a truly portable device. The main challenge is the design of a geometry that optimally trades image quality for system size. The goal of …
Real Time Frequency Analysis Of Signals From Lasso Catheter For Radiofrequency Ablation During Atrial Fibrillation, Prashant Yadav
Real Time Frequency Analysis Of Signals From Lasso Catheter For Radiofrequency Ablation During Atrial Fibrillation, Prashant Yadav
Theses and Dissertations
Real time spectrum analysis of signals obtained through lasso catheter during radiofrequency ablation of pulmonary vein was performed to determine the channel with dominant frequency. Threshold algorithm was used for signals which could be classified as type I and type II AF. Type III AF Signals which were highly fractionated or differentiated were evaluated for frequency content by performing Fast Fourier Transform. Data from Seven patients was collected and an episode of 180 ± 40 seconds was recorded and analyzed for each pulmonary vein that showed electrical activation. Frequency spectra for one second segment of signal for each channel were …
Joint Center Movement Analysis And 3d Motion Modeling Of Upper Arm - Comparison Of Several Algorithms With The Visual 3-D Program, Leena Joseph
Theses and Dissertations
600 out of every 100,000 people in the United States today suffer from some form of cerebellar disease that causes major abnormalities in the equilibrium and aligned, coordinated movement of the body. Hence it becomes essential to diagnose the extent of the movement and gait disorder and provide required therapy to the patients. Various developments have been made in the designing and application of interactive software system for body positioning. Object oriented design techniques are used in the field of software engineering for interactive geometric representation of system behavior. Motion analysis of the upper and lower extremities of the body …
The Use Of Computerized Dynamic Posturography To Assess The Balance In Individuals With Parkinson's Disease, Theresa Erin Mcguirk
The Use Of Computerized Dynamic Posturography To Assess The Balance In Individuals With Parkinson's Disease, Theresa Erin Mcguirk
Theses and Dissertations
Postural instability is one of the hallmarks of Parkinson's disease (PD), currently evaluated using several subjective tools. However, the nature and degree of the resulting balance deficit is not well specified by these tools. Computerized dynamic posturography (CDP) provides an objective assessment by isolating and quantifying sensory and motor contributions to balance control. The purpose of this study was to compare balance in individuals with PD to a control group using CDP (NeuroCom Smart Balance Master® system). Testing took place at the Southeast Parkinson's disease Research Education and Clinical Center (PADRECC), an interdisciplinary center of excellence for people with PD …