Open Access. Powered by Scholars. Published by Universities.®
University of Arkansas, Fayetteville
Health, Human Performance and Recreation Undergraduate Honors Theses
Articles 1 - 1 of 1
Full-Text Articles in Engineering
Development Of A Semi-Interpenetrating Network Hydrogel To Study The Effects Of Mild Traumatic Brain Injury On Astrocyte Remodeling, Amanda Ederle
Development Of A Semi-Interpenetrating Network Hydrogel To Study The Effects Of Mild Traumatic Brain Injury On Astrocyte Remodeling, Amanda Ederle
Health, Human Performance and Recreation Undergraduate Honors Theses
Traumatic brain injuries (TBIs) are a widespread public health concern affecting over 2.5 million people in the United States alone (1). TBIs are the leading cause of death and disability in children (ages 0-14), and their devastating effects can also be seen in vast population subsets such as professional athletes and combat soldiers (1).
Damaged astrocytes, the specialized glial cells associated with the maintenance of the brain’s environment, respond to injury by altering regulation of certain proteins and ion channels in an attempt to maintain homeostasis (3). Studies have also shown that following a TBI, astrocytes seek to regenerate, a …