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Full-Text Articles in Engineering

Immunostimulatory Effects Of Antigen-Conjugated Inp/Zns Quantum Dot Nanoparticles In An Avian Model, Christopher Lyle May 2018

Immunostimulatory Effects Of Antigen-Conjugated Inp/Zns Quantum Dot Nanoparticles In An Avian Model, Christopher Lyle

Theses and Dissertations

Due to their unique physicochemical and enhanced immunostimulatory properties, quantum dot (QD) nanoparticles have shown increasing promise in biomedical research applications including bioimaging, drug delivery, and as vaccine adjuvants. Toxicity, however, remains a concern for the use of QD in these applications and thus, there is an increased demand for effective in vitro and in vivo systems to measure the bioactivity of QD. In this study in vitro and in vivo chicken models were used to investigate the effects of QD on innate and adaptive immunity. Chicken macrophage cultures were treated in vitro with QD to measure macrophage activation and ...


An Investigation Of Humeral Stress Fractures In Racing Thoroughbreds Using A 3d Finite Element Model In Conjunction With A Bone Remodeling Algorithm, Ryan James Moore Feb 2010

An Investigation Of Humeral Stress Fractures In Racing Thoroughbreds Using A 3d Finite Element Model In Conjunction With A Bone Remodeling Algorithm, Ryan James Moore

Master's Theses and Project Reports

The humerus of a racing horse Thoroughbred is highly susceptible to stress fractures at a characteristic location as a result of cyclic loading. The propensity of a Thoroughbred to exhibit humeral fracture has made equines useful models in the epidemiology of stress fractures. In this study, a racing Thoroughbred humerus was simulated during training using a 3D finite element model in conjunction with a bone remodeling algorithm. Nine muscle forces and two contact forces were applied to the 3-dimensional finite element model, which contains four separate load cases representing fore-stance, mid-stance, aft-stance, and standing. Four different training programs were incorporated ...


A Systematic Evaluation Of Laying Hen Housing For Improved Hen Welfare, Angela Renee Green Jan 2008

A Systematic Evaluation Of Laying Hen Housing For Improved Hen Welfare, Angela Renee Green

Retrospective Theses and Dissertations

Husbandry practices for egg production vary throughout the world. Current production systems are typically classified as caged, cage-free, or free range in terms of housing style. The research presented supplements the existing knowledge base for laying-hen housing. Where possible, a systematic assessment approach was used in the comprehensive literature review, and combined field monitoring and controlled-environment laboratory studies. The results of this research demonstrate: differing environmental conditions and hen health under different housing schemes with varying weather; no difference in heat and moisture production for varying stocking density and group size; no clear advantage of offering additional space for coping ...


Dietary Strategies To Reduce Air Emissions From Laying Hen Operations , Wei Wu-Haan Jan 2006

Dietary Strategies To Reduce Air Emissions From Laying Hen Operations , Wei Wu-Haan

Retrospective Theses and Dissertations

The objectives of the current study were to evaluate the effectiveness of feeding a reduced emission diet (R) containing 6.9% of a gypsum-zeolite mixture and slightly reduced crude protein (CP) to 21-, 38-, and 59-wk old Hy-line W36 hens (trial 1, 2, and 3, respectively) on hen performance, emissions of NH3, H2S, NO, NO2, CO2 , CH4, non-methane total hydrocarbon, and apparent digestibility compared to feeding a commercial diet (C), and to compare different methods of estimating nutrient excretion from laying hens in environmental chambers. At each age, 640 hens were allocated randomly to one of eight environmental chambers for ...


Total Elbow Replacement In The Dog: Development And Evaluation , Michael Gerard Conzemius Jan 2000

Total Elbow Replacement In The Dog: Development And Evaluation , Michael Gerard Conzemius

Retrospective Theses and Dissertations

Elbow osteoarthritis (OA) is the most common cause of forelimb lameness in the dog. The goal of nonsurgical and/or surgical management of the diseases that cause elbow OA is to slow the progression OA in the joint and reduce lameness in the patient. Nonsurgical and surgical management of these conditions frequently leads to unsatisfactory results. Current treatment alternatives for dogs with moderate to severe elbow OA include nonsurgical management, removing loose bodies and osteophytes from the joint, and arthrodesis. Similarly, these treatments frequently lead to a poor outcome. Improvements in implant design and surgical techniques have made total elbow ...


Development Of An Empirical Model Of Human Sweating And A Semi-Empirical Model Of Human Thermoregulation , Jennifer Jane Walker Jan 1999

Development Of An Empirical Model Of Human Sweating And A Semi-Empirical Model Of Human Thermoregulation , Jennifer Jane Walker

Retrospective Theses and Dissertations

The physiology of the human thermoregulatory response to changes in environment and work load has been studied from the perspective of both the physiologist and the engineer. Both fields have brought certain skills and tools to the effort. An effort to bring together the understanding gained from these two perspectives has been lacking. In this work a model for the sweat response and a model for the thermoregulatory response to changes in room temperature were developed. These models were developed using the modeling tools of engineering and the knowledge contained in past experimental data;An empirical model of the sweat ...


Development Of A Coupled Model Of The Cardiorespiratory And Thermoregulatory Systems , Dawn Denise Downey Jan 1998

Development Of A Coupled Model Of The Cardiorespiratory And Thermoregulatory Systems , Dawn Denise Downey

Retrospective Theses and Dissertations

A model of the human body which integrates the variables involved in temperature regulation and blood gas transport within the cardiovascular and respiratory systems is presented in this dissertation. It expands upon previous work developed by the author to model the competition between skin and muscles when both require increased blood flows during exercise and/or heat stress. First, a detailed study of the control relations used to predict skin blood flow was undertaken. Four other control relations employed in the model were also examined and modified as indicated by empirical results found in literature;Several important cases were then ...


A Quantitative Estimation Of Regulation And Transport Limitations In The Human Cardiopulmonary System , Sharmista Chatterjee Jan 1997

A Quantitative Estimation Of Regulation And Transport Limitations In The Human Cardiopulmonary System , Sharmista Chatterjee

Retrospective Theses and Dissertations

The object of this dissertation is to quantitatively describe the regulation of some of the exchange processes within the human body. Conceptually this dissertation is divided into two sections. In the first section a macroscopic view was adopted to describe the overall regulation of the cardiovascular and respiratory systems. These overall system models were used as heuristic tools to gain an understanding of physiological behavior in micro-gravity. In the second section, a microscopic view was used to estimate the role played by the surfactant system of the lung in regulating the transfer of fluid across the pulmonary-capillary wall;The basis ...


Calcium Phosphate Ceramic Composites Used For Orthopedic Implant Applications , Curtis Eugene Olson Jan 1996

Calcium Phosphate Ceramic Composites Used For Orthopedic Implant Applications , Curtis Eugene Olson

Retrospective Theses and Dissertations

The objective of the first of two research projects was to make a new composite material that would have both bone bonding capabilities and appropriate mechanical properties for use in orthopedic applications. Implant-bone responses were compared using transcortical implants designed from osteoceramic fired in air, osteoceramic fired in hydrogen, 316L stainless steel mixed with aggregates of osteoceramic, 316L stainless steel, and ultra high molecular weight polyethylene mixed with aggregates of osteoceramic. The osteoceramic material, developed at Iowa State University, was a biologically active composite consisting of tricalcium phosphate and magnesium aluminate spinel;Ten of each of these implants were placed ...


Computer Simulation Of Coronary Blood Flow , Brian Christopher Frake Jan 1995

Computer Simulation Of Coronary Blood Flow , Brian Christopher Frake

Retrospective Theses and Dissertations

A computer model to simulate coronary fluid dynamics has been developed which can give some insight into the role of hemodynamics in health and disease. Although this study focuses mainly on coronary blood flow, the complete model consists of all major branches of the systemic circulation as well as the left epicardial coronary circulation;The flow equations are obtained by integrating the one-dimensional continuity and momentum equations over the cross-section of the artery to give a relationship between the primary variables of interest, the pressure and flowrate. An arctangent model was used as a constitutive equation to describe the pressure-area ...


Evaluation Of A Direct Systolic Cardiac Augmentation Device On A Canine Heart During Global Postischemic Dysfunction , Raymond Kenneth Kudej Jan 1994

Evaluation Of A Direct Systolic Cardiac Augmentation Device On A Canine Heart During Global Postischemic Dysfunction , Raymond Kenneth Kudej

Retrospective Theses and Dissertations

The performance of a direct systolic cardiac augmentation device, called a heart cuff, was evaluated during application of the device to canine hearts following a period of global ischemia. The heart cuff was developed to provide temporary, partial assistance to a heart experiencing postischemic myocardial dysfunction (myocardial stunning);Myocardial stunning is a postischemic mechanical dysfunction which results from a sublethal tissue injury occurring at the time of reperfusion. The injury will resolve if the myocardial tissue is given sufficient time to recover. Stunning may significantly contribute to the morbidity and mortality of many cardiac procedures because of the temporary inability ...


An Investigation Into The Role Of Arterial Wall Vibration In The Pathogenesis Of Atherosclerosis , Becky Bellatti Bittle Jan 1994

An Investigation Into The Role Of Arterial Wall Vibration In The Pathogenesis Of Atherosclerosis , Becky Bellatti Bittle

Retrospective Theses and Dissertations

Fifty percent of all the deaths in the Western world can be attributed to diseases of the cardiovascular system. A major player amongst these diseases is atherosclerosis. Atherosclerosis is the localized thickening of the arterial wall and is primarily due to the proliferation of fibrous tissue and smooth muscle cells in conjunction with the deposition of lipids within the wall. The hypothesis investigated was that high frequency, low amplitude vibratory environments similar to those found in regions of disturbed flow, which are coincident with intimal thickenings, the earliest stage of atherosclerosis, do elicit a proliferative response in vascular smooth muscle ...


Granular Cold-Water-Soluble Starch: Preparation, Characterization, And Its Use On Controlled Release Of Atrazine , Jen-Fang Chen Jan 1993

Granular Cold-Water-Soluble Starch: Preparation, Characterization, And Its Use On Controlled Release Of Atrazine , Jen-Fang Chen

Retrospective Theses and Dissertations

Granular cold-water-soluble (GCWS) starches were prepared by alcoholic-alkaline treatments. The method was carried out by treating starches with mixtures of ethanol and alkali, primarily NaOH solution (3M), to swell starch granules. The treated starches were then neutralized with HCl (3M, in 100% alcohol), washed with aqueous alcohol solution, and dried in an oven at 80°C for 3 h. The method was effective to wide varieties of starches, including high amylose starches, normal starches, and waxy starches. The efficacy of the method depended mainly on concentrations of NaOH and ethanol, and reaction temperature. Different reaction conditions gave products different properties ...


Development Of An Ocular Drug Release System For Cattle , Thomas Quang Dinh Jan 1991

Development Of An Ocular Drug Release System For Cattle , Thomas Quang Dinh

Retrospective Theses and Dissertations

An erodible ring-shaped ocular insert containing an antibiotic (tylosin tartrate) has been developed for treatment of infectious bovine keratoconjunctivitis (IBK). Four additional tasks have been completed: (1) a test to determine the retention time of the ocular device in the eyes of the calves, (2) an in vitro test to determine the degradation characteristics of the device, (3) an in vitro study to obtain the drug release profiles of the insert, and (4) a study to compare the use of rings and a field treatment method using infected cattle;The device remained in the eyes an average of 3.92 ...


Hydrogel Ocular Inserts For The Treatment Of Infectious Bovine Keratoconjunctivitis , Je-Phil Ryoo Jan 1989

Hydrogel Ocular Inserts For The Treatment Of Infectious Bovine Keratoconjunctivitis , Je-Phil Ryoo

Retrospective Theses and Dissertations

Hydrogel coated ring shaped ocular inserts (containing the antibiotic, tylosin tartrate) were used in an evaluation of the effectiveness of polymeric ocular drug release devices for treating infectious bovine keratoconjunctivitis. Two major in vivo tests were done: a treatment test using infected cattle and a test to evaluate ring retention characteristics. The in vivo experiments represent the first experiments using hydrogel ocular inserts containing an antibiotic for treating infectious bovine keratoconjunctivitis;The bacterium, Moraxella bovis, was used to replicate the disease. In the infection tests, ten calves were challenged with 2.4 x 10[superscript]8 - 1.6 x 10 ...


Continuous Measurement Of Oxyhemoglobin Concentration By Reflection Oximetry And Its Use In Controlling An Artificial Heart, Howard Hugh Erickson Jan 1966

Continuous Measurement Of Oxyhemoglobin Concentration By Reflection Oximetry And Its Use In Controlling An Artificial Heart, Howard Hugh Erickson

Retrospective Theses and Dissertations

No abstract provided.


Analysis Of Some Biological Systems Using State Variable Theory , Duane Ellison Sander Jan 1964

Analysis Of Some Biological Systems Using State Variable Theory , Duane Ellison Sander

Retrospective Theses and Dissertations

No abstract provided.


Use Of Heat Exchangers In The Ventilation Of Animal Shelters , Amin Aly Ibrahim Jan 1950

Use Of Heat Exchangers In The Ventilation Of Animal Shelters , Amin Aly Ibrahim

Retrospective Theses and Dissertations

No abstract provided.