Engineering Commons^™

Autonomic Activity In Gulf War Veterans Using Heart Rate And Systolic Blood Pressure Variability, Maryann S. Fam

Theses

Heart rate variability (HRV) describes variations of heart rate and is attributed to cyclic fluctuations in autonomic tone. The different methods of heart rate variability analysis allow for a non-invasive assessment of autonomic activity. This study analyzes the heart rate variability through both frequency domain methods and joint time-frequency domain methods which were executed through the LabVJEW graphical programming language. These algorithms were utilized to assess autonomic nervous system activity in Gulf War veterans with no health complaints versus Gulf War veterans with chronic fatigue syndrome. The heart rate variability analysis was obtained from acquired measurements of heart rate and …

Drowsy Driver Data Acquisition System, Rafael Norat

Theses

This thesis focuses on detecting the drowsiness of a driver based on differentiation of the EEG signal activity between the eyes open and eyes closed states. Here, it is observed that there is a significant increase 'in a 10 Hz component of the alpha rhythm activity when the subject under test closes his / her eyes. This phenomenon was observed when electrodes were attached to the occipital region. A more desirable approach is to develop a non-intrusive measurement based on a multiturn differential coil combination utilizing a low noise high gain amplifier. The system developed here used an 80,000 turn …

Biomechanical Evaluation Of Patient Transfers, Charles Costa

Theses

The purpose of this study is to identify the problem encountered when a patient with limited strength and mobility needs assistance in transferring from a wheelchair to another location.

This study took advantage of ergonomic techniques to isolate the source of stress, and limited these stresses according to the standards of the National Institute of Safety and Health Administration.

A device was developed whereby the stresses of a patient transfer were eliminated. By using a conventional wheelchair and a recliner as a starting point, effectively combining these components into a single multifunctional unit the goal of reducing stress was achieved. …

A Study Of The Parameters And Stipulations Involved In The Design Of Prosthetic Limb Socket Liners, Sally F. Shady

Theses

The objective of this thesis is to illustrate the parameters that define and characterize the elements necessary for an optimal prosthetic socket interface design. Previous studies have revealed that the industry is manufacturing materials that are causing irregularities in gait patterns and causing major discomfort for transtibial amputees. As a result, chances for recovery and rehabilitation of many patients have been greatly reduced.

This study has indicated that the success of a socket liner depends on quantitative and qualitative factors that assess the overall efficacy of an artificial limb. Quantitative analysis is observed through calculations and deviations in gait cycles, …

Design Of A Fluoride Removal Water Treatment System For A Guatemalan Community: An Exercise In Global Engineering, Jason R. El Koubi

Honors Theses

No abstract provided.

Late Deflation Study : Hemodynamic Effects Of Iab Timing In Humans, Manal Morcos

Theses

Conventional IABP timing deflates 100% of the balloon volume before the onset of left ventricular ejection and has been well established in the literature as a safe and effective method. Yet, recent studies suggest that deflation of the IAB at or near the onset of systole improve myocardial efficiency (Kern, 1999, 1129). To test whether deflation of the JAB at a later deflation time reduces left ventricular workload and enhances coronary perfusion, four timing methods were evaluated in 20 patients: T₁ (100% JAB volume deflated before onset of ejection), T₂ (60% IAB volume deflated before and 40% volume …

A Study Of Factors Affecting Cardiovascular Reactivity, Andrew Gill Ventura

Theses

This pilot study was conducted to determine what affects the cardiovascular reactivity of different people. Variables such as the order of stress-inducing and relaxing activities, performing multiple tasks on different days, personality, familial history of diseases, and general health were investigated as to their effects, if any, on cardiovascular reactivity.

Ten healthy, normal male subjects, aged 18 - 33 years, volunteered to be subjected to studies on three experimental days, the first one being for gathering information. On the second and third days, the subjects performed the following activities: mental arithmetic, numeric repetition, 10 breaths-per-minute (bpm) paced-breathing, and normal breathing, …

Investigation Of The Relevance Of Heart Rate Variability Changes After Heart Transplantation, Sheeba Arnold

Theses

Heart transplantation has become an established treatment for end-stage heart disease. However, the shortage of donor organs is a major problem and long-term results are limited by allograft rejection. Heart rate variability (HRV) has emerged as a popular noninvasive research tool in cardiology. Analysis of HRV is regarded as a valid technique to assess the sympathovagal balance of the heart. The primary goal of this study was to investigate the relevance of heart rate variability changes after heart transplantation. It was found that spectral analysis of HRV is useful in detecting rejection episodes. Heart transplantation leaves the donor heart denervated. …

Development And Testing Of A Simulated Closed Loop Drug Delivery System For Chf Patients Under Milrinone Administration, Runa Shah

Theses

The purpose of this thesis project is the development and testing of a simulated closed loop drug delivery (CLDD) system that consists of a pharmacokinetic, physiological, and feedback-controlling model. The focus of this study is on the control of milrinone inflision to maintain cardiac output at desired setpoint range for patients suffering from congestive heart failure (CHF). The simulated CLDD system is written in VisSim dynamic simulation language for an IBM-compatible PC.

Milrinone pharmacokinetics are represented by a three compartment model. The physiological model consists of the cardiovascular system model linked to the pharmacodynamic submodel of milrinone. The feedback-controlling model …

Bottom-Up Design Of Artificial Neural Network For Single-Lead Electrocardiogram Beat And Rhythm Classification, Srikanth Thiagarajan

Doctoral Dissertations

Performance improvement in computerized Electrocardiogram (ECG) classification is vital to improve reliability in this life-saving technology. The non-linearly overlapping nature of the ECG classification task prevents the statistical and the syntactic procedures from reaching the maximum performance. A new approach, a neural network-based classification scheme, has been implemented in clinical ECG problems with much success. The focus, however, has been on narrow clinical problem domains and the implementations lacked engineering precision. An optimal utilization of frequency information was missing. This dissertation attempts to improve the accuracy of neural network-based single-lead (lead-II) ECG beat and rhythm classification. A bottom-up approach defined …