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Articles 1 - 30 of 57
Full-Text Articles in Engineering
Risk Estimation And Expert Judgment: The Case Of Yucca Mountain, Kristin Shrader-Frechette
Risk Estimation And Expert Judgment: The Case Of Yucca Mountain, Kristin Shrader-Frechette
RISK: Health, Safety & Environment (1990-2002)
Professor Shrader-Frechette discusses factors responsible for acute disagreement between the federal government and Nevada citizens over potential Risks at Yucca Mountain and focuses on the use of expert judgment, concluding that some of them appear to exemplify "bad science." That aside, she argues that 1,000 year predictions cannot be made from current knowledge of geology or, e.g., institutional behavior and concludes that permanent disposal of radioactive waste is currently impossible.
Book Review, Peter C. Christensen
Book Review, Peter C. Christensen
RISK: Health, Safety & Environment (1990-2002)
Review of: MARY R. ENGLISH, SITING LOW-LEVEL RADIOACTIVE WASTE DISPOSAL FACILITIES: THE PUBLIC POLICY DILEMMA. (Quorum Books 1992) [278 pp.], Appendices, index, introduction, references. LC-91-42774; ISBN 0-89930-560-1. [$49.95 cloth. One Madison Avenue, New York NY 10010.]
34th Rocky Mountain Conference On Applied Spectroscopy
34th Rocky Mountain Conference On Applied Spectroscopy
Rocky Mountain Conference on Magnetic Resonance
Program and registration information for the 34th annual meeting of the Rocky Mountain Conference on Applied Spectroscopy, co-sponsored by the Colorado Section of the American Chemical Society and the Rocky Mountain Section of the Society for Applied Spectroscopy. Held in Denver, Colorado, August 2-6, 1992.
Book Review, Allan M. Wheatcraft
Book Review, Allan M. Wheatcraft
RISK: Health, Safety & Environment (1990-2002)
Review of the following: LEONARD EVANS, TRAFFIC SAFETY AND THE DRIVER. (Van Nostrand Reinhold 1991) [404 pp.] About the author, author index, figures, notes, preface, subject index, tables. LC 90-44233, ISBN 0-4421-00163-0. [Cloth $51.95. P.O.B. 668, Florence KY 41022-0668.]
The Safety Risks Of Proposed Fuel Economy Legislation, John D. Graham
The Safety Risks Of Proposed Fuel Economy Legislation, John D. Graham
RISK: Health, Safety & Environment (1990-2002)
Based on, e.g., a comprehensive assessment of what is known of factors influencing automobile safety, previous industry responses to requirements for fuel economy and prior success of regulators in reducing injuries, Professor Graham concludes that pending fuel economy bills are apt to add 1650 fatalities and 8500 serious accidents to the annual highway toll. He also presents several short-term and long-term strategies for simultaneously saving fuel and lives.
Stubble : Friend And Foe, Department Of Agriculture And Food, Western Australia
Stubble : Friend And Foe, Department Of Agriculture And Food, Western Australia
Journal of the Department of Agriculture, Western Australia, Series 4
Several articles in this issue of the Journal of Agriculture discuss some of the important issues of stubble management. The articles are condensed from some of the papers presented at a stubble workshop at Geraldton in 1991.
Interaction Of Liposomal Drug Delivery Systems With Cells And Tissues: Microscopic Studies, M. Foldvari, G. T. Faulkner, C. Mezei, M. Mezei
Interaction Of Liposomal Drug Delivery Systems With Cells And Tissues: Microscopic Studies, M. Foldvari, G. T. Faulkner, C. Mezei, M. Mezei
Cells and Materials
Liposomes , as drug carriers, can be administered into the body by several routes e.g. intravenously, intraperitoneally, intramuscularly, intratracheally and topically among others. Radiolabelled markers are suitable to monitor the distribution and elimination of liposomes, but the tissue deposition of intact liposomes, the mode and sites of drug release from the liposomes and liposome-cell interactions cannot be investigated morphologically. Microscopic techniques could provide information regarding the intact state of liposomes and possibly the dynamics of liposomes in tissues provided that they can be identified with certainty in vivo. This is a formidable problem and in spite of several attempts, there …
Microstructure Of Mica Glass-Ceramics And Interface Reactions Between Mica Glass-Ceramics And Bone, W. Holand, W. Gotz, G. Carl, W. Vogel
Microstructure Of Mica Glass-Ceramics And Interface Reactions Between Mica Glass-Ceramics And Bone, W. Holand, W. Gotz, G. Carl, W. Vogel
Cells and Materials
This review paper characterizes glass-ceramics containing mica as main crystal phase. The phase formation reactions in dependence of the chemical composition and the microstructure are shown. Microstructure of mica glass-ceramics has been studied by electron replica and scanning electron microscopic (SEM) techniques.
Mica glass-ceramics have previously been developed in Si02-B20rA120rMgO-F--base glasses. The material is machinable because of the precipitation of micas of fluorophlogopite-type. Also, a machinable glass-ceramic for dental applications was developed based on KMg2_5(Si40 10)F2-micas. We developed mica glass-ceramics in the Si02-Al20rMgO-NaiO-K20-F glass system. Phase formation within these glasses was observed by SEM. A double controlled nucleation and crystallization …
The Effect Of Polymethylmethacrylate Bone Cement Vibration On The Bone-Cement Interface, A. M. C. Thomas, D. J. W. Mcminn, M. Haddaway, I. W. Mccall
The Effect Of Polymethylmethacrylate Bone Cement Vibration On The Bone-Cement Interface, A. M. C. Thomas, D. J. W. Mcminn, M. Haddaway, I. W. Mccall
Cells and Materials
Low frequency vibration of polymethylmethacrylate (PMMA) bone cement reduces the viscosity of the cement by shear thinning. The effect of this low frequency vibration on the bone-cement interface was studied using microfocal radiography (MFR) and scanning electron microscopy (SEM). Effects were studied in-vitro and in-vivo. In-vitro, samples of Palacos low viscosity PMMA were placed on blocks of Kiel bone and vibrated. MFR and SEM demonstrated an improvement in the appearance of the bone-cement interface. In-vivo, PMMA was injected into the upper tibia of the dog. An assessment of the effect of high and low pressure injection, and the effect of …
Ultrastructural Assessment Of Lesion Development In The Collared Rabbit Carotid Artery Model, J. E. Beesley, A. C. Honey, J. F. Martin
Ultrastructural Assessment Of Lesion Development In The Collared Rabbit Carotid Artery Model, J. E. Beesley, A. C. Honey, J. F. Martin
Cells and Materials
Cellular reactions associated with the formation of lesions generated in the carotid artery of rabbits fed either normal or high cholesterol diets by the placement of a flexible, silastic collar around the artery, were studied by electron microscopy.
Endothelial cells remained as a monolayer throughout lesion development. The endothelial cell surface in both experimental and sham operated carotids, 4 hours and 8 hours after the initiation of the experiments, were covered with platelets and leukocytes. Neutrophils were present until 7 days in the arteries from within the collar of animals maintained on a normal diet, but only to 1 day …
Applications Of Fourier Transform Infrared (Ft-Ir) Microscopy To The Study Of Mineralization In Bone And Cartilage, Adele L. Boskey, Nancy Pleshko, Stephen B. Doty, Richard Mendelsohn
Applications Of Fourier Transform Infrared (Ft-Ir) Microscopy To The Study Of Mineralization In Bone And Cartilage, Adele L. Boskey, Nancy Pleshko, Stephen B. Doty, Richard Mendelsohn
Cells and Materials
Knowledge of the phase, composition, and crystallite size and perfection of the mineral in normal and abnormally calcified tissues provides insight into the mechanism by which this mineral was deposited. These data also can be used to develop rational therapies for pathological conditions characterized by abnormal mineral deposition. As illustrated in this review, coupling of an optical microscope with a Fourier transform infrared (FT-IR) spectrophotometer permits the mapping at 20 μm spatial resolution of changes in mineral characteristics (content, particle size, composition) in the growth plate, in bone biopsies, in mineralizing cell culture systems, and in soft tissue calcifications. Based …
The Effect Of Serial Passaging Of Lactobacilli In Liquid Medium On Their Physico-Chemical And Structural Surface Characteristics, Pieter L. Cuperus, Henny C. Van Der Mei, Gregor Reid, Andrew W. Bruce, Antoine E. Khoury, Paul G. Rouxhet, Henk J. Busscher
The Effect Of Serial Passaging Of Lactobacilli In Liquid Medium On Their Physico-Chemical And Structural Surface Characteristics, Pieter L. Cuperus, Henny C. Van Der Mei, Gregor Reid, Andrew W. Bruce, Antoine E. Khoury, Paul G. Rouxhet, Henk J. Busscher
Cells and Materials
The aim of this study was to examine the effect of serial passaging in liquid medium on physico-chemical and structural surface characteristics of two lactobacillus strains. To this end, starting cultures (p = 1) of urogenital isolate L. acidophilus RC 14 and poultry isolate L. fermentum B54 were serially passaged in liquid medium up to 20 times (p = 20). In both strains, similar physico-chemical and structural changes were observed following serial passaging. According to water contact angle measurements , cells in p = 20 cultures became less hydrophobic. Microelectrophoresis showed that isoelectric points shifted towards the acidic region upon …
The Incorporation Of Glass-Ceramic Implants In Bone After Surface Conditioning Glow-Discharge Treatment, C. M. Muller-Mai, C. Voigt, R. E. Baier, U. M. Gross
The Incorporation Of Glass-Ceramic Implants In Bone After Surface Conditioning Glow-Discharge Treatment, C. M. Muller-Mai, C. Voigt, R. E. Baier, U. M. Gross
Cells and Materials
Glow discharge (GD)-treated and autoclaved glass-ceramics of bone-bonding and non-bonding type were implanted into the femoral diaphysis of rats for 3, 7, 14 and 28 days and were investigated by applying light microscopy and histomorphometry , and scanning and transmission electron microscopy. More bone and chondroid, and faster osteoid development were observed at glow-discharge treated implants even in nonbonding implants when compared to autoclaved controls. Ultrastructural investigations showed a higher leach ing- rate of GD-treated bone-bonding implants during the early days after implantation leading to a higher rugosity, whereas no morphological changes were observed on non-bonding implant surfaces. More extracellular …
Nothing Recedes Like Success - Risk Analysis And The Organizational Amplification Of Risks, William R. Freudenburg
Nothing Recedes Like Success - Risk Analysis And The Organizational Amplification Of Risks, William R. Freudenburg
RISK: Health, Safety & Environment (1990-2002)
Professor Freudenburg believes that there is room for improvement in Risk analysis, particularly in drawing on systematic studies of human behavior in the calculation of real, empirical probabilities of failure. The need is argued to be especially acute where technological Risks are associated with low expected probabilities of failure and are managed by human organizations for extended periods of time. This permits complacency to set in.
Reply To Valverde, Paul B. Thompson
Reply To Valverde, Paul B. Thompson
RISK: Health, Safety & Environment (1990-2002)
Professor Thompson responds to Valverde's argument, in the last issue, that his approach to Risk puts too much emphasis on the distinction between Risk subjectivism and Risk objectivism. In doing so, he asserts, inter alia, that anchoring Risk judgments in a probabilistic framework does not go far enough in rejecting reigning Risk-analysis notions of "real Risk."
Summary Of Workshop To Review An Omb Report On Regulatory Risk Assessment And Management, John S. Evans, John D. Graham, George M. Gray, Adrienne Hollis
Summary Of Workshop To Review An Omb Report On Regulatory Risk Assessment And Management, John S. Evans, John D. Graham, George M. Gray, Adrienne Hollis
RISK: Health, Safety & Environment (1990-2002)
Summary of the results of an invitational workshop conducted to peer review the 1990 OMB report, CURRENT REGULATORY ISSUES IN Risk ASSESSMENT AND Risk MANAGENMENTIN REGULATORY PROGRAM OF THE UNITED STATES GOVERNMENT, APRIL 1, 1990 - MARCH 31, 1991.
The Risk Of Reliance On Perceived Risk, Frank B. Cross
The Risk Of Reliance On Perceived Risk, Frank B. Cross
RISK: Health, Safety & Environment (1990-2002)
Professor Cross's comment is closely related to the debate between Thompson and Valverde. Using examples that do not commonly appear in the "Risk" literature, he argues that: Giving weight to perceived Risk may seem liberal insofar as it gives more say to the "little guy," but giving perceived Risk too much weight could have distinctly illiberal social consequences.
Clinical Applications Of Recombinant Gene Technology: Bone And Cartilage Repair, Thomas A. Einhorn
Clinical Applications Of Recombinant Gene Technology: Bone And Cartilage Repair, Thomas A. Einhorn
Cells and Materials
Over the past decade, the field of molecular biology has given rise to the development of the applied discipline of molecular medicine. Based on recent developments using recombinant gene technology, genetic mapping analysis and other investigational tools, the physician and surgeon is now ready to begin using those instruments in the diagnosis and treatment of musculoskeletal disease. This article reviews the history of scientific exploration in recombinant gene technology as it applies to bone and cartilage repair. Clinical cases are presented to show how the fruits of scientific knowledge may be brought to bear on some of the more challenging …
Scanning Electron Microscope Observation Of Lubricious Polymer Surface For Medical Use, Hiroyuki Inoue, Yoshikimi Uyama, Emiko Uchida, Yoshito Ikada
Scanning Electron Microscope Observation Of Lubricious Polymer Surface For Medical Use, Hiroyuki Inoue, Yoshikimi Uyama, Emiko Uchida, Yoshito Ikada
Cells and Materials
A peculiar textured structure was found by scanning electron microscopic (SEM) observation on polymer films surface-grafted with water-soluble polyacrylamide and poly(N,N-dimethylacrylamide) after exposure to ozone. The grafted surface became very hydrophilic and highly lubricated when brought into contact with water, due to hydration of the grafted surface layer. Unless water was present, the surface did not become slippery at all. SEM of the grafted surface revealed different profiles, depending on the graft density as well as the process of drying prior to the SEM observation. There was no significant difference between the virgin and the surface-grafted film, when air-dried under …
Evaluation Of Bacterial Glycocalyx Preservation And Staining By Ruthenium Red, Ruthenium Red-Lysine And Alcian Blue For Several Methanotroph And Staphylococcal Species, Theresa A. Fassel, James E. Van Over, Christopher C. Hauser, Lorie E. Buchholz, Charles E. Edmiston, James R. Sanger, Charles C. Remsen
Evaluation Of Bacterial Glycocalyx Preservation And Staining By Ruthenium Red, Ruthenium Red-Lysine And Alcian Blue For Several Methanotroph And Staphylococcal Species, Theresa A. Fassel, James E. Van Over, Christopher C. Hauser, Lorie E. Buchholz, Charles E. Edmiston, James R. Sanger, Charles C. Remsen
Cells and Materials
The cationic reagents, ruthenium red (RR), alcian blue (AB) and ruthenium red -lysine were compared for ultrastructural preservation and staining of the bacterial glycocalyx. En bloc RR, AB and RR-lysine procedures, and a glutaraldehyde/OsO4 fixation withou t cationic reagent, were evaluated by transmission electron microscopy (TEM) for several methanotroph and staphylococcal species. The glutaraldehyde/OsO4 fixation was totally ineffective in preserving or staining the glycocalyx material in all species studied. The RR procedure was more effective than the glutaraldehyde/OsO4 fixation but was generally less so than the RR-lysine procedure. By the RR-lysine procedure, extensive layers that were often filamentous or fibrous …
A Model For A Model: Pressure Jackets On Nude Mice With Implants Of Hypertrophic Scars, C. Ward Kischer, Jana Pindur
A Model For A Model: Pressure Jackets On Nude Mice With Implants Of Hypertrophic Scars, C. Ward Kischer, Jana Pindur
Cells and Materials
The hypertrophic scar, a consequence of deep surface injury, is peculiar to humankind. Subcutaneous implants of these tissues in nude mice provide a quasi - animal model for experimental use. An efficacious treatment to promote acceleration of maturation of the hypertrophic scar is controlled topical pressure produced by flexible dacron fabric wraps. Implants in the nude mouse provide a model for study of the effects of pressure. Preliminary results indicate that those implants in nude mice, responding favorably to pressure jackets, show changes consistent with those previously obtained in human studies. The collagen matrix shows reduced density and parallel layering …