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Full-Text Articles in Engineering

Detection Of Methylation On Dsdna Using Nanopores In Mos2 Membrane, David Estrada Oct 2017

Detection Of Methylation On Dsdna Using Nanopores In Mos2 Membrane, David Estrada

Materials Science and Engineering Faculty Publications and Presentations

Methylation at the 5-carbon position of the cytosine nucleotide base in DNA has been shown to be a reliable diagnostic biomarker for carcinogenesis. Early detection of methylation and intervention could drastically increase the effectiveness of therapy and reduce the cancer mortality rate. Current methods for detecting methylation involve bisulfite genomic sequencing, which are cumbersome and demand a large sample size of bodily fluids to yield accurate results. Hence, more efficient and cost effective methods are desired. Based on our previous work, we present a novel nanopore-based assay using a nanopore in a MoS2 membrane, and the methyl-binding protein (MBP), …


Amorphous Boron Nanorod As An Anode Material For Lithium-Ion Batteries At Room Temperature, Changjian Deng, Miu Lun Lau, Riley Parrish, Kassiopeia A. Smith, Hui Xiong Aug 2017

Amorphous Boron Nanorod As An Anode Material For Lithium-Ion Batteries At Room Temperature, Changjian Deng, Miu Lun Lau, Riley Parrish, Kassiopeia A. Smith, Hui Xiong

Materials Science and Engineering Faculty Publications and Presentations

We report an amorphous boron nanorod anode material for lithium-ion batteries prepared through smelting non-toxic boron oxide in liquid lithium. Boron in theory can provide capacity as high as 3099 mAh g-1 by alloying with Li to form B4Li5. However, experimental studies of boron anode were rarely reported for room temperature lithium-ion batteries. Among the reported studies the electrochemical activity and cycling performance of bulk crystalline boron anode material are poor at room temperature. In this work, we utilized amorphous nanostructured one-dimensional (1D) boron material aiming at improving the electrochemical reactivity between boron and lithium ions …


Metrology Of Dna Arrays By Super-Resolution Microscopy, Christopher M. Green, Kelly Schutt, Noah Morris, Reza M. Zadegan, William L. Hughes, Wan Kuang, Elton Graugnard Aug 2017

Metrology Of Dna Arrays By Super-Resolution Microscopy, Christopher M. Green, Kelly Schutt, Noah Morris, Reza M. Zadegan, William L. Hughes, Wan Kuang, Elton Graugnard

Materials Science and Engineering Faculty Publications and Presentations

Recent results in the assembly of DNA into structures and arrays with nanoscale features and patterns have opened the possibility of using DNA for sub-10 nm lithographic patterning of semiconductor devices. Super-resolution microscopy is being actively developed for DNA-based imaging and is compatible with inline optical metrology techniques for high volume manufacturing. Here, we combine DNA tile assembly with state-dependent super-resolution microscopy to introduce crystal-PAINT as a novel approach for metrology of DNA arrays. Using this approach, we demonstrate optical imaging and characterization of DNA arrays revealing grain boundaries and the temperature dependence of array quality. For finite arrays, analysis …


Phase Separation In Ti-6al-4v Alloys With Boron Additions For Biomedical Applications: Scanning Kelvin Probe Force Microscopy Investigation Of Microgalvanic Couples And Corrosion Initiation, P. H. Davis, K. Robles, K. Livingston, S. Johns, V. A. Ravi, E. Graugnard, M. F. Hurley Aug 2017

Phase Separation In Ti-6al-4v Alloys With Boron Additions For Biomedical Applications: Scanning Kelvin Probe Force Microscopy Investigation Of Microgalvanic Couples And Corrosion Initiation, P. H. Davis, K. Robles, K. Livingston, S. Johns, V. A. Ravi, E. Graugnard, M. F. Hurley

Materials Science and Engineering Faculty Publications and Presentations

To investigate the effect of boron additions on the corrosion behavior of Ti-6Al-4V for potential use in biomedical implants and devices, cast samples of Ti-6Al-4V were alloyed with 0.01% to 1.09% boron by weight and subjected to hot isostatic pressing. Subsequent analysis via scanning Kelvin probe force microscopy and scanning electron microscopy/energy-dispersive spectroscopy revealed the presence of both alpha (α) and beta (β) phase titanium, enriched in aluminum and vanadium, respectively. At all concentrations, boron additions affected the grain structure and were dispersed throughout both phases, but above the solubility limit, needle-like TiB structures also formed. …


Testing Our Assumptions: The Role Of First Course Grade And Course Level In Mathematics And English, Janet Callahan, Marcia Belcheir Aug 2017

Testing Our Assumptions: The Role Of First Course Grade And Course Level In Mathematics And English, Janet Callahan, Marcia Belcheir

Materials Science and Engineering Faculty Publications and Presentations

Methods that provide an early indicator of factors that affect student persistence are important to colleges and universities. This quantitative research focused on the role of level of entry mathematics and English and also on grades earned in those classes as they relate to persistence after one year. The research showed that by far, the variable most predictive of first-time, full-time students enrolling one year later was earning a grade of “A” in English. Compared to those who did not pass their first English course, students who earned an “A” were three times more likely to persist. The variables which …


Computationally Connecting Organic Photovoltaic Performance To Atomistic Arrangements And Bulk Morphology, Matthew L. Jones, Eric Jankowski Jul 2017

Computationally Connecting Organic Photovoltaic Performance To Atomistic Arrangements And Bulk Morphology, Matthew L. Jones, Eric Jankowski

Materials Science and Engineering Faculty Publications and Presentations

Rationally designing roll-to-roll printed organic photovoltaics requires a fundamental understanding of active layer morphologies optimized for charge separation and transport, and which ingredients can be used to self-assemble those morphologies. In this review article we discuss advances in three areas of computational modeling that provide insight into active layer morphology and the charge transport properties that result. We explain the computational bottlenecks prohibiting atomistically-detailed simulations of device-scale active layers and the coarse-graining and hardware acceleration strategies for overcoming them. We review coarse-grained simulations of organic photovoltaic active layers and show that high throughput simulations of experimentally-relevant length scales are now …


Establishing Doctoral Programs In Electrical Engineering, Materials Science And Engineering, And Computing In An Emerging Research Institution: Lessons Learned And Best Practices, Janet Callahan, Cheryl B. Schrader, Darryl P. Butt, Timothy Anderson, Tammi Vacha-Hasse, Amy J. Moll Jun 2017

Establishing Doctoral Programs In Electrical Engineering, Materials Science And Engineering, And Computing In An Emerging Research Institution: Lessons Learned And Best Practices, Janet Callahan, Cheryl B. Schrader, Darryl P. Butt, Timothy Anderson, Tammi Vacha-Hasse, Amy J. Moll

Materials Science and Engineering Faculty Publications and Presentations

Over the past decade, three doctoral programs have been launched at Boise State University. The first doctoral program established was in Electrical and Computer Engineering, selected because of the need for a trained workforce in the region. The other two doctoral programs, Materials Science and Engineering, and Computing, were from the start designed as interdisciplinary degree programs. That is, they were designed for the participation of not just program faculty within the division, but for the participation of program faculty with related research interests in other departments at the university. This paper presents the steps taken to launch the programs, …


Ten Years Later: Where Are They Now?, Janet Callahan, Donna C. Llewellyn, Vicki Stieha, Ann E. Delaney Jun 2017

Ten Years Later: Where Are They Now?, Janet Callahan, Donna C. Llewellyn, Vicki Stieha, Ann E. Delaney

Materials Science and Engineering Faculty Publications and Presentations

This paper explores the educational and career trajectories of the alumnae of an outreach activity for girls. The outreach activity was originally developed using an integrated marketing approach to attract girls into engineering programs.1 The program, a two day, overnight experience for rising 9th, 10th and 11th grade girls, focuses on showcasing engineering as an exciting, creative activity, including activities developed from that perspective. Started in 2005 and held annually since then, a total of over 500 girls have participated, with approximately 85% of them coming from Boise State University’s immediate metropolitan area. Facilitated by …


Listening And Negotiation Ii, Adjo A. Amekudzi-Kennedy, Kevin D. Hall, Trevor Scott Harding, Amy J. Moll, Janet Callahan Jun 2017

Listening And Negotiation Ii, Adjo A. Amekudzi-Kennedy, Kevin D. Hall, Trevor Scott Harding, Amy J. Moll, Janet Callahan

Materials Science and Engineering Faculty Publications and Presentations

This paper is based on a panel held in June, 2017 in Columbus, Ohio, jointly sponsored by the Women in Engineering Division and by the Minorities in Engineering Division. It is focused on negotiation, with an emphasis on providing practical strategies that are relevant in an academic setting. The panel featured academic leaders at multiple levels, including professor, chair and dean, from diverse engineering institutions, ranging from teaching-centric to heavily research-focused. Panelists discussed strategies for negotiation, with an emphasis on an approach that meets the interests of both parties to the extent possible. The panel was administrated with an opening …


Vertically Integrated Projects (Vip) Programs: Multidisciplinary Projects With Homes In Any Discipline, Jocelyn B. S. Cullers, William L. Hughes, Donna C. Llewellyn Jun 2017

Vertically Integrated Projects (Vip) Programs: Multidisciplinary Projects With Homes In Any Discipline, Jocelyn B. S. Cullers, William L. Hughes, Donna C. Llewellyn

Materials Science and Engineering Faculty Publications and Presentations

A survey of papers in the ASEE Multidisciplinary Engineering Division over the last three years shows three main areas of emphasis: individual courses; profiles of specific projects; and capstone design courses. However, propagating multidisciplinary education across the vast majority of disciplines offered at educational institutions with varying missions requires models that are independent of the disciplines, programs, and institutions in which they were originally conceived. Further, models that can propagate must be cost effective, scalable, and engage and benefit participating faculty. Since 2015, a consortium of twenty-four institutions has come together around one such model, the Vertically Integrated Projects (VIP) …


Effects Of Proton Irradiation On Structural And Electrochemical Charge Storage Properties Of Tio2 Nanotube Electrode For Lithium-Ion Batteries, Kassiopeia A. Smith, Andreas I. Savva, Changjian Deng, Hui Xiong Jun 2017

Effects Of Proton Irradiation On Structural And Electrochemical Charge Storage Properties Of Tio2 Nanotube Electrode For Lithium-Ion Batteries, Kassiopeia A. Smith, Andreas I. Savva, Changjian Deng, Hui Xiong

Materials Science and Engineering Faculty Publications and Presentations

The effects of proton irradiation on nanostructured metal oxides have been investigated. Recent studies suggest that the presence of structural defects (e.g. vacancies and interstitials) in metal oxides may enhance the material’s electrochemical charge storage capacity. A new approach to introduce defects in electrode materials is to use ion irradiation as it can produce a supersaturation of point defects in the target material. In this work we report the effect of low-energy proton irradiation on amorphous TiO2 nanotube electrodes at both room temperature and high temperature (250 ˚C). Upon room temperature irradiation the nanotubes demonstrate an irradiation-induced phase transformation …


Liquid-Gas Surface Tension Voltage Dependence During Electrowetting On Dielectric Of 5-90 Nm Gold Nanofluids, Saeid Vafaei, Karthik Chinnathambi, Theodorian Borca-Tasciuc Mar 2017

Liquid-Gas Surface Tension Voltage Dependence During Electrowetting On Dielectric Of 5-90 Nm Gold Nanofluids, Saeid Vafaei, Karthik Chinnathambi, Theodorian Borca-Tasciuc

Materials Science and Engineering Faculty Publications and Presentations

This article investigates the effective liquid-gas surface tension changes of water and 5-90nm gold nanofluids measured during electrowetting on dielectric experiments. The Young-Laplace equation for sessile droplets in air was solved to fit the experimental droplet shape and determine the effective liquid-gas surface tension at each applied voltage. A good agreement between experimental droplet shapes and the predictions was observed for all the liquids investigated in applied range of 0-30V. The measured liquid-gas effective surface tensions of water and gold nanofluid decreased with voltage. At a given voltage, the effective liquid-gas surface tension of gold nanofluids initially decreased as the …


Availability: A Metric For Nucleic Acid Strand Displacement Systems, Xiaoping Olson, Shohei Kotani, Jennifer E. Padilla, Natalya Hallstrom, Sara Goltry, Jeunghoon Lee, Bernard Yurke, William L. Hughes, Elton Graugnard Jan 2017

Availability: A Metric For Nucleic Acid Strand Displacement Systems, Xiaoping Olson, Shohei Kotani, Jennifer E. Padilla, Natalya Hallstrom, Sara Goltry, Jeunghoon Lee, Bernard Yurke, William L. Hughes, Elton Graugnard

Materials Science and Engineering Faculty Publications and Presentations

DNA strand displacement systems have transformative potential in synthetic biology. While powerful examples have been reported in DNA nanotechnology, such systems are plagued by leakage, which limits network stability, sensitivity, and scalability. An approach to mitigate leakage in DNA nanotechnology, which is applicable to synthetic biology, is to introduce mismatches to complementary fuel sequences at key locations. However, this method overlooks nuances in the secondary structure of the fuel and substrate that impact the leakage reaction kinetics in strand displacement systems. In an effort to quantify the impact of secondary structure on leakage, we introduce the concepts of availability and …


Signal-To-Noise Ratio Enhancement Using Graphene-Based Passive Microelectrode Arrays, Sepideh Rastegar, Justin Stadlbauer, Kiyo Fujimoto, Kari Mclaughlin, David Estrada, Kurtis D. Cantley Jan 2017

Signal-To-Noise Ratio Enhancement Using Graphene-Based Passive Microelectrode Arrays, Sepideh Rastegar, Justin Stadlbauer, Kiyo Fujimoto, Kari Mclaughlin, David Estrada, Kurtis D. Cantley

Materials Science and Engineering Faculty Publications and Presentations

This work is aimed toward the goal of investigating the influence of different materials on the signal-to-noise ratio (SNR) of passive neural microelectrode arrays (MEAs). Noise reduction is one factor that can substantially improve neural interface performance. The MEAs are fabricated using gold, indium tin oxide (ITO), and chemical vapor deposited (CVD) graphene. 3D-printed Nylon reservoirs are then adhered to the glass substrates with identical MEA patterns. Reservoirs are filled equally with a fluid that is commonly used for neuronal cell culture. Signal is applied to glass micropipettes immersed in the solution, and response is measured on an oscilloscope from …


Application Of Artificial Neural Networks To Identify Equilibration In Computer Simulations, Michael H. Leibowitz, Evan D. Miller, Michael M. Henry, Eric Jankowski Jan 2017

Application Of Artificial Neural Networks To Identify Equilibration In Computer Simulations, Michael H. Leibowitz, Evan D. Miller, Michael M. Henry, Eric Jankowski

Materials Science and Engineering Faculty Publications and Presentations

Determining which microstates generated by a thermodynamic simulation are representative of the ensemble for which sampling is desired is a ubiquitous, underspecified problem. Artificial neural networks are one type of machine learning algorithm that can provide a reproducible way to apply pattern recognition heuristics to underspecified problems. Here we use the open-source TensorFlow machine learning library and apply it to the problem of identifying which hypothetical observation sequences from a computer simulation are "equilibrated" and which are not. We generate training populations and test populations of observation sequences with embedded linear and exponential correlations. We train a two-neuron artificial network …