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Full-Text Articles in Engineering

Consolidated Chamber Design And Protocol For Olfactory Conditioning Assay With Drosophila Melanogaster, Sasha Bronovitskiy, Andres Castillo, Michael Yan, Fang Ju Lin May 2023

Consolidated Chamber Design And Protocol For Olfactory Conditioning Assay With Drosophila Melanogaster, Sasha Bronovitskiy, Andres Castillo, Michael Yan, Fang Ju Lin

Journal of the South Carolina Academy of Science

The olfactory conditioning assay is widely used in Alzheimer’s disease research to quantify learning and memory in Drosophila melanogaster. The assay tests ability to recall an aversive conditioned stimulus of scent paired with electrical shock when presented a choice between shock-associated and unrelated scents. The T-maze, a commonly used apparatus for olfactory conditioning assays, employs an elevator mechanism to transfer live flies from the shock-delivering training chamber to the scent selection point. This elevator mechanism is known to cause fly casualty. T-mazes are not commercially available and often difficult to reproduce. Other existing variations of olfactory conditioning apparatuses use …


Table Of Contents Jun 2022

Table Of Contents

Journal of the South Carolina Academy of Science

No abstract provided.


The Effect Of Low Dose Penicillin On Tumor Development In ApcMin/+ Mice, Kinsey Ann Sierra Meggett Oct 2021

The Effect Of Low Dose Penicillin On Tumor Development In ApcMin/+ Mice, Kinsey Ann Sierra Meggett

Theses and Dissertations

Antibiotics have been our most effective weapon against bacterial infections since their discovery in the early 1900s. Their use has been critical in reducing mortality rate from infectious diseases. However, in the last few decades, the overuse of antibiotics, beginning at an early age and into adulthood, has become a growing concern globally. Penicillin is one of many extensively used antibiotics in early childhood that has been used to treat childhood infections. Recent studies showed that exposure to low dose penicillin can have adverse effects leading to chronic illness such as diabetes, allergies, inflammation, and susceptibility to obesity, with the …


Osteon Mimetic Scaffolding, Janay Clytus Apr 2018

Osteon Mimetic Scaffolding, Janay Clytus

Senior Theses

The purpose of this research is to provide an alternative to naturally derived bone grafts. There is a gap in the supply of donors and the demand of bone tissue. Artificial scaffold creation can work as an implant and decrease the shortage of bone grafts and increase the range of injuries that can be repaired. Current research focuses on optimizing mechanical properties such as porosity, improving vascularization using cells, and generating osteoconductivity. For osteodifferentiation, mesenchymal stem cells (MSCs) can differentiate into mesodermal lineages such as chondrocytes, osteoblasts, adipocytes, and tenocytes by supplementing cultures with lineage-specific soluble factors (Marchetti). Co-culturing ECFCs …


Photosynthetic Performance And Anti-Oxidative Response Of Cornus Controversa Seedlings Under Cadmium And Lead Stress, Xinyu Huang, Yonglei Jiang, Xiaomao Cheng, Lilan Deng, Xuncheng Liu Jun 2015

Photosynthetic Performance And Anti-Oxidative Response Of Cornus Controversa Seedlings Under Cadmium And Lead Stress, Xinyu Huang, Yonglei Jiang, Xiaomao Cheng, Lilan Deng, Xuncheng Liu

Faculty Publications

The photosynthetic efficiency of Cornus controversa leaves was decreased significantly under Cd treatment while it was not affected by Pb exposure. Cd decreased while Pb treatment increased the chlorophyll contents of Cornus controversa leaves. Furthermore, the peroxidase (GPX) activities were decreased after Cd treatment while elevated by Pb exposure in Cornus controvera seedlings. In addition, both Cd and Pb exposures increased the malondialdehyde (MDA) and proline contents and elevated the superoxide dismutase (SOD) activities of Cornus controvera seedlings. Collectively, these results indicated that Cornus controversa may be more tolerant to Pb than Cd toxicity. This finding will contribute to the …


Art Or Science?, Allison Marsh Jan 2014

Art Or Science?, Allison Marsh

Section 3: Imaging the Fast Moving

No abstract provided.


Complex Of Myoglobin With Phenol Bound In A Proximal Cavity, Xiao Huang, Chunxue Wang, Lesa R. Celeste, Leslie L. Lovelace, Shengfang Sun, John H. Dawson, Lukasz Lebioda Nov 2012

Complex Of Myoglobin With Phenol Bound In A Proximal Cavity, Xiao Huang, Chunxue Wang, Lesa R. Celeste, Leslie L. Lovelace, Shengfang Sun, John H. Dawson, Lukasz Lebioda

Faculty Publications

Sperm whale myoglobin (Mb) has weak dehaloperoxidase activity and catalyzes the peroxidative dehalogenation of 2,4,6-trichlorophenol (TCP) to 2,6-dichloroquinone. Crystals of Mb and of its more active G65T variant were used to study the binding of TCP, 4-iodophenol (4-IP) and phenol. The structures of crystals soaked overnight in a 10 mM solution of phenol revealed that a phenol molecule binds in the proximal cavity, forming a hydrogen bond to the hydroxyl of Tyr146 and hydrophobic contacts which include interactions with C and C of the proximal histidine His93. The phenol position corresponds to the strongest xenon binding site, Xe1. It …


Conclusion Panel, Allison Marsh Jan 2012

Conclusion Panel, Allison Marsh

Section 6: Conclusion

No abstract provided.


Usc's Nanocenter, Allison Marsh Jan 2012

Usc's Nanocenter, Allison Marsh

Section 5: Imaging at the Nano Scale

No abstract provided.


Fact Or Fiction?, Allison Marsh Jan 2012

Fact Or Fiction?, Allison Marsh

Section 5: Imaging at the Nano Scale

No abstract provided.


Nano Imaging, Allison Marsh Jan 2012

Nano Imaging, Allison Marsh

Section 5: Imaging at the Nano Scale

No abstract provided.


Choosing An Instrument, Allison Marsh Jan 2012

Choosing An Instrument, Allison Marsh

Section 5: Imaging at the Nano Scale

No abstract provided.


Mapping The Ocean Frontier, Allison Marsh Jan 2012

Mapping The Ocean Frontier, Allison Marsh

Section 4: Imaging the Concealed

No abstract provided.


Spotlight On Usc: South Carolina Institute For Anthropology And Archaeology, Allison Marsh Jan 2012

Spotlight On Usc: South Carolina Institute For Anthropology And Archaeology, Allison Marsh

Section 4: Imaging the Concealed

No abstract provided.


Seeing With Sound, Allison Marsh Jan 2012

Seeing With Sound, Allison Marsh

Section 4: Imaging the Concealed

No abstract provided.


World Ocean Floor, Courtesy Of The Library Of Congress, Allison Marsh Jan 2012

World Ocean Floor, Courtesy Of The Library Of Congress, Allison Marsh

Section 4: Imaging the Concealed

No abstract provided.


Marie Tharp At Her Drafting Table, Courtesy Of The Lamont-Doherty Earth Observatory, Earth Institute, Columbia University, Allison Marsh Jan 2012

Marie Tharp At Her Drafting Table, Courtesy Of The Lamont-Doherty Earth Observatory, Earth Institute, Columbia University, Allison Marsh

Section 4: Imaging the Concealed

No abstract provided.


Why Do We Collect?, Allison Marsh Jan 2012

Why Do We Collect?, Allison Marsh

Section 2: Imaging the Microscopic

No abstract provided.


Imaging And Aesthetics, Allison Marsh Jan 2012

Imaging And Aesthetics, Allison Marsh

Section 2: Imaging the Microscopic

No abstract provided.


Capturing Motion, Allison Marsh Jan 2012

Capturing Motion, Allison Marsh

Section 3: Imaging the Fast Moving

No abstract provided.


Understanding Fracture, Allison Marsh Jan 2012

Understanding Fracture, Allison Marsh

Section 3: Imaging the Fast Moving

No abstract provided.


Listen, Allison Marsh Jan 2012

Listen, Allison Marsh

Section 3: Imaging the Fast Moving

No abstract provided.


Photographic Evidence, Allison Marsh Jan 2012

Photographic Evidence, Allison Marsh

Section 3: Imaging the Fast Moving

No abstract provided.


Spotlight On Usc: Mechanical Engineering, Allison Marsh Jan 2012

Spotlight On Usc: Mechanical Engineering, Allison Marsh

Section 3: Imaging the Fast Moving

No abstract provided.


Influencing Art, Allison Marsh Jan 2012

Influencing Art, Allison Marsh

Section 3: Imaging the Fast Moving

No abstract provided.


What Is Nanotechnology?, Allison Marsh Jan 2012

What Is Nanotechnology?, Allison Marsh

Section 5: Imaging at the Nano Scale

No abstract provided.


Spotlight On Usc: Department Of Art, Allison Marsh Jan 2012

Spotlight On Usc: Department Of Art, Allison Marsh

Section 5: Imaging at the Nano Scale

No abstract provided.


Art Versus Image, Allison Marsh Jan 2012

Art Versus Image, Allison Marsh

Section 5: Imaging at the Nano Scale

No abstract provided.


Nanotechnology In Everyday Life, Allison Marsh Jan 2012

Nanotechnology In Everyday Life, Allison Marsh

Section 5: Imaging at the Nano Scale

No abstract provided.


Spotlight On Usc: A.C. Moore Herbarium, Allison Marsh Jan 2012

Spotlight On Usc: A.C. Moore Herbarium, Allison Marsh

Section 2: Imaging the Microscopic

No abstract provided.