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University of South Carolina

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Full-Text Articles in Engineering

Identifying Prevalent Mathematical Pathways To Engineering In South Carolina, Eliza Gallagher, Christy Brown, D. Andrew Brown, Kristin Kelly Frady, Patrick Bass, Michael A. Matthews, Thomas T. Peters, Robert J. Rabb, Ikhalfani Solan, Ronald W. Welch, Anand K. Gramopadhye Jun 2018

Identifying Prevalent Mathematical Pathways To Engineering In South Carolina, Eliza Gallagher, Christy Brown, D. Andrew Brown, Kristin Kelly Frady, Patrick Bass, Michael A. Matthews, Thomas T. Peters, Robert J. Rabb, Ikhalfani Solan, Ronald W. Welch, Anand K. Gramopadhye

Faculty Publications

National data indicate that initial mathematics course placement in college is a strong predictor of persistence to degree in engineering, with students placed in calculus persisting at nearly twice the rate of those placed below calculus. Within the state of South Carolina, approximately 95% of engineering-intending students who initially place below calculus are from in-state. In order to make systemic change, we are first analyzing system-wide data to identify prevalent educational pathways within the state, and the mathematical milestones along those pathways taken by students in engineering and engineering-related fields. This paper reports preliminary analysis of that data to understand ...


Development Of Rule-Based Recognition Systems For Continuous Monitorization Of Pulse Oximetry, Brian Delehanty Apr 2018

Development Of Rule-Based Recognition Systems For Continuous Monitorization Of Pulse Oximetry, Brian Delehanty

Senior Theses

Pulse Oximeters provide a convenient, non-invasive method to quickly gather information about a patient's pulse rate (PR) and arterial blood oxygen saturation (SpO2). Many pulse oximeters lack alert systems that notify caregivers if a patient's readings go outside the healthy range, and pulse oximeters that have these mechanisms are significantly more expensive. This project set out to write a program using LabVIEW that collects pulse oximeter data via Bluetooth and generates an alert when readings persist in the abnormal range for more than fifteen seconds. Due to privacy laws that allow pulse oximeter manufacturers to not disclose ...


Integration Of A Sensory Driven Model For Hand Grasp Function In 3d Printed Prostheses, Austin T. Hetherington Apr 2018

Integration Of A Sensory Driven Model For Hand Grasp Function In 3d Printed Prostheses, Austin T. Hetherington

Senior Theses

My Honors Thesis was completed through the Biomedical Engineering senior design project I worked on. Our project took a mechanically operated 3D printed prosthetic hand and automated the process by which it makes a grasp. The purpose of this project was to provide an affordable, automatic prosthetic hand to those either capable and incapable of wrist flexion. The current 3D printed prosthetic models require users to bend their wrist to initiate a simple grasp. However, our design took an alternative approach by using an EMG sensor placed on the ventral side of the forearm to record muscle activity, which, upon ...


Optimization Of Microfluidic Chip Fabrication Via Femtosecond Laser Ablation, Kenneth Aycock Apr 2018

Optimization Of Microfluidic Chip Fabrication Via Femtosecond Laser Ablation, Kenneth Aycock

Senior Theses

Microfluidic devices have become staple tools in biomedical research and have a promising future as low cost, point-of-care (POC) diagnostic devices. Despite the advancements in microfluidic device technology, the manipulation and fabrication of these systems can be tedious and expensive. Repeatable techniques in which computer-aided designs are translated into microfluidic systems in a matter of minutes are highly desirable both for researchers and manufacturers. Laser ablation of tape substrates has shown promise in producing cost-effective, rapidly manipulable devices, but the work done thus far has utilized continuous wave lasers that perform suboptimally due to the relatively short wavelengths used and ...


Economic Analysis Of Reactive Distillation In The Production Of Tert-Amyl Methyl Ether (Tame), Clayton Brandenburg Apr 2018

Economic Analysis Of Reactive Distillation In The Production Of Tert-Amyl Methyl Ether (Tame), Clayton Brandenburg

Senior Theses

Aspen HYSYS was used to make two flowsheets, one with plug flow reactors and distillation columns and another with a reactive distillation column, to see which flowsheet was better at producing tert-amyl methyl ether (TAME) and which one was more economically feasible. The goal was to produce 15,000 metric tons of TAME per year by reacting a naptha stream with methanol. It was found that both flowsheets were capable of producing the desired amounts of TAME and with product purities around 100%. The conversions of the reactive distillation was 93.93%, significantly higher than the 72.48% and 76 ...


Osteon Mimetic Scaffolding, Janay Clytus Apr 2018

Osteon Mimetic Scaffolding, Janay Clytus

Senior Theses

The purpose of this research is to provide an alternative to naturally derived bone grafts. There is a gap in the supply of donors and the demand of bone tissue. Artificial scaffold creation can work as an implant and decrease the shortage of bone grafts and increase the range of injuries that can be repaired. Current research focuses on optimizing mechanical properties such as porosity, improving vascularization using cells, and generating osteoconductivity. For osteodifferentiation, mesenchymal stem cells (MSCs) can differentiate into mesodermal lineages such as chondrocytes, osteoblasts, adipocytes, and tenocytes by supplementing cultures with lineage-specific soluble factors (Marchetti). Co-culturing ECFCs ...


Increasing Drug Delivery Efficacy Of Drug-Coated Balloons, Alexander Galan, Eric Bidinger, Franco Godoy, Shrusti Patel Apr 2018

Increasing Drug Delivery Efficacy Of Drug-Coated Balloons, Alexander Galan, Eric Bidinger, Franco Godoy, Shrusti Patel

Senior Theses

Peripheral artery disease (PAD), the narrowing of peripheral arteries located in areas such as the arms and legs, is a common disease that affects 12% to 20% of people over 65. Numerous therapies have been developed to treat PAD, the most recent technology being drug-coated balloons. Drug-coated balloons release drugs, such as Paclitaxel (PTX), into the arterial wall during balloon angioplasty to locally treat PAD. Current levels of drug transfer from the balloon to the vascular endothelium are at a low 10%-18%. Our Biomedical Engineering Senior Design project aims to increase drug delivery of drug-coated balloons by manipulating the ...


Photovoltaic Inverter Control To Sustain High Quality Of Service, Yan Chen Jan 2018

Photovoltaic Inverter Control To Sustain High Quality Of Service, Yan Chen

Theses and Dissertations

The increasing penetration of distributed solar photovoltaic (PV) generation presents both challenges and opportunities for distribution systems. The intermittent nature of solar irradiance may lead to power quality degradation. At the same time, PV inverters –if properly designed and operated– can be used to improve power quality. The goal of this dissertation is to develop power flow optimization methods for power distribution networks with high penetration of PV generation. The approaches proposed in this dissertation have been tested using the modified version of the IEEE 34-node distribution system and the IEEE 123-node distribution system, as well as the validated model ...


The Rational Synthesis Of Bimetallic Catalysts On Oxide Supports, Andrew Phillip Wong Jan 2018

The Rational Synthesis Of Bimetallic Catalysts On Oxide Supports, Andrew Phillip Wong

Theses and Dissertations

Catalysts play an important role in many chemical reactions. However, simple impregnated monometallic catalysts are often limited in their function. One way to overcome this limitation is through the incorporation of a secondary metal to the catalysts. These bimetallic catalysts often have synergistic benefits not observed in the monometallic analogues. Here, we focused on the synthesis of bimetallic catalysts using rational methods in order to improve catalyst function; specifically by tuning the particle size, morphology, and composition. The two methods of interests were Strong Electrostatic Adsorption (SEA) and Electroless Deposition (ED). An adaptation of SEA to bimetallic catalysts (coSEA) was ...


Hydrothermal Carbonization Of Food Waste For Nutrient Recovery And Reuse, Ifeolu M. Idowu Jan 2018

Hydrothermal Carbonization Of Food Waste For Nutrient Recovery And Reuse, Ifeolu M. Idowu

Theses and Dissertations

Food waste represents a rather large and currently underutilized source of potentially available and reusable nutrients. Laboratory-scale experiments evaluating the hydrothermal carbonization of food wastes collected from restaurants were conducted to understand how changes in feedstock composition and carbonization process conditions influence primary and secondary nutrient fate. Results from this work indicate that at all evaluated reaction times and temperatures, the majority of nitrogen, calcium, and magnesium remain integrated within the solid-phase, while the majority of potassium and sodium reside in the liquid-phase. The fate of phosphorus is dependent on reaction times and temperatures, with solid-phase integration increasing with higher ...


Impact Of Critical Path Method (Cpm) Of Scheduling On On-Time Completion Of Transportation Projects, Fahim Ahmed Jan 2018

Impact Of Critical Path Method (Cpm) Of Scheduling On On-Time Completion Of Transportation Projects, Fahim Ahmed

Theses and Dissertations

This study addresses the effectiveness of Critical Path Method (CPM) scheduling on project delivery. Specifically, the on-time completion of projects with and without a CPM schedule is explored. The paper uses data from 2,097 South Carolina transportation projects let after February 2008 and substantially completed by August 2015. The delay analysis uses the original contract completion date as well as the completion date adjusted by change orders. Chi-Squared tests are used to examine the relationship between CPM scheduled projects and delayed projects, and t-tests are used to compare the mean delay (in days) between CPM scheduled and unscheduled projects ...


Monitoring The Progress Of Damage In A Sicf-Sicm Composite Nuclear Fuel Cladding Under Internal Pressure Using Acoustic Emission, Luis H. Alva Jan 2018

Monitoring The Progress Of Damage In A Sicf-Sicm Composite Nuclear Fuel Cladding Under Internal Pressure Using Acoustic Emission, Luis H. Alva

Theses and Dissertations

The relation between the progress of damage and the acoustic emission (AE) activity of a nuclear grade Sif-SiCm composite tubing under internal pressure was studied. The nuclear grade Sif-SiCm composite tubing is manufactured by the company General Atomics (GA) and made of nuclear grade HI Nicalon type S fiber preforms following a chemical vapor infiltration (CVI) technique. Sif-SiCm composites are good candidates to replace current nuclear fuel cladding materials because of the good chemical stability and strength at high temperatures. In this work, a Sif-SiCm composite tubing was tested under internal pressure at room temperature (RT) to study the damage ...


Quantifying Time Retarded Electromagnetic Fields And Their Applications In Transmission Lines, Brandon Thomas Gore Jan 2018

Quantifying Time Retarded Electromagnetic Fields And Their Applications In Transmission Lines, Brandon Thomas Gore

Theses and Dissertations

Modern baseband signaling that facilitates the passing of information over high speed interconnects such as copper twin-ax cable and printed circuit boards supports single line data rates of 100 Gbps. Next generation bandwidth requirements of electrical links are approaching frequencies up to 50 GHz. Yet, signal integrity engineers that analyze these interconnects rely on models with underlying assumptions and limited extensions beyond those proposed in the 19th century to describe per unit length characteristics of Resistance, Inductance, Conductance, and Capacitance (RLGC) for transatlantic telegraph cable. An excluded phenomenon is the time retarded behavior of electromagnetic fields. The aim of this ...


Development Of Models And Solution Methods For Different Drayage Applications, Samaneh Shiri Jan 2018

Development Of Models And Solution Methods For Different Drayage Applications, Samaneh Shiri

Theses and Dissertations

In the last decades, intermodal freight transport is becoming more attractive in the global supply chains and freight transport policy makings. Intermodal freight transport provides a cost-effective, reliable, and efficient movement of freight by utilizing the strengths of different transport modes. The initial and final segment of intermodal freight transport, performed by truck, is known as “drayage.” The scheduling of truck movements in drayage operation within the service area of an intermodal terminal is an operational problem which leads to a truck scheduling problem that determines the efficient schedule of trucks while satisfying all transportation demands and constraints. Drayage accounts ...


Stabilization Of Silicon And Germanium Based High Capacity Anodes For Lithium Ion Batteries, Kuber Mishra Jan 2018

Stabilization Of Silicon And Germanium Based High Capacity Anodes For Lithium Ion Batteries, Kuber Mishra

Theses and Dissertations

Lithium-ion batteries (LIBs) have been the driver of the widespread application of portable electronics. As the electronic devices have been more powerful and versatile, the pressing demand for higher energy density batteries have led the extensive explorations of novel materials for high capacity electrodes. Despite several breakthroughs in literature, the current state of art LIBs still uses the battery chemistry developed in early 1990s.The keys challenges for switching to other high capacity electrodes have been high cost, non-linear scalability and poorer electrochemical performance. This dissertation focusses on development of high capacity electrodes in order to increase the energy density ...


Ontology-Guided Pre-Release Inference Disruption, Mark Stephen Daniels Jan 2018

Ontology-Guided Pre-Release Inference Disruption, Mark Stephen Daniels

Theses and Dissertations

We investigate privacy violations occurring when non-confidential patient data is combined with medical domain ontologies to disclose a patient’s protected health information (PHI). We propose a framework that detects privacy violations and eliminates undesired inferences. Our inference channel removal process is based on controlling the release of the data items that lead to undesired inferences. These data items are either blocked from release or generalized to eliminate the disclosure of the PHI. We show that our method is sound and complete. Soundness means the only inference paths generated logically follow from released data and corresponding domain knowledge. Completeness means ...


Enhance Flow Boiling In Microchannels By Regulating Two-Phase Transport Patterns, Wenming Li Jan 2018

Enhance Flow Boiling In Microchannels By Regulating Two-Phase Transport Patterns, Wenming Li

Theses and Dissertations

Flow boiling in microchannels is one of the most promising cooling techniques for microelectronics. Using latent heat by vaporization can significantly improve heat dissipation of high power density electronic devices. Most of the failure of electronic devices is induced by the occurrence of critical heat flux (CHF), which defines the maximum operating conditions. However, the vigorous rapid generation of vapor through phase change leads to chaotic two-phase flows in microchannels, resulting in flowinstability in terms of severe flow, temperature and pressure drop fluctuations. Particularly, the very well-known bubble confinement exacerbates the two-phase flow instabilities and greatly deteriorates heat transfer performance ...


Fundamental Aspects Of A Novel Technology For Abatement Of Indoor Allergens, Odell Lendor Glenn Jr. Jan 2018

Fundamental Aspects Of A Novel Technology For Abatement Of Indoor Allergens, Odell Lendor Glenn Jr.

Theses and Dissertations

The overall goal of this research was to develop a novel approach to reduce the potency of certain asthma triggers, namely, proteins produced by pests or pets in indoor environments. The broad hypothesis of the research was that naturally occurring essential oils will demonstrate enhanced denaturing ability. In any indoor environment, allergens are bound to dry dust particles. In this work, the effectiveness of using dry ice and CO2 with potential for essential oils on dry allergenic proteins through CFD modeling and ELISA methods were evaluated.

There are three objectives central to this work. The first objective was to apply ...


System Optimization And Material Development Of Solid Oxide Cells For Energy Conversion And Storage, Libin Lei Jan 2018

System Optimization And Material Development Of Solid Oxide Cells For Energy Conversion And Storage, Libin Lei

Theses and Dissertations

Solid oxide cells (SOCs) can convert chemical energy to electricity in the fuel cell mode and store electricity to chemicals in the electrolysis mode. However, there are still critical barriers, such as energy efficiency and durability, for the development and commercialization of SOCs. The objective of this dissertation is to apply system optimization and materials design to address the critical barriers for solid oxide cells in energy conversion and energy storage applications. One major focus of the dissertation is related to improve energy efficiency, enhance the cell performance and achieve multifunctionality in solid oxide electrolysis cells (SOECs). In addition, development ...


Bytecode-Based Multiple Condition Coverage: An Initial Investigation, Srujana Bollina Jan 2018

Bytecode-Based Multiple Condition Coverage: An Initial Investigation, Srujana Bollina

Theses and Dissertations

Masking occurs when one condition prevents another condition from influencing the output of a Boolean expression. Logic-based adequacy criteria such as Multiple Condition Coverage (MCC) are designed to overcome masking at the within-expression level, but can offer no guarantees about masking in subsequent expressions. As a result, a Boolean expression written as a single complex statement will yield test cases that are more likely to overcome masking than when the expression is written as series of simple statements. Many approaches to automated analysis and test case generation for Java systems operate not on the source code representation of code, but ...


Association Between Mechanics And Biology In Vascular Graft Remodeling, David Andrew Prim Jan 2018

Association Between Mechanics And Biology In Vascular Graft Remodeling, David Andrew Prim

Theses and Dissertations

Coronary artery bypass grafting (CABG) restores myocardial perfusion in patients with severe coronary artery disease by utilizing autografts – usually at least one of the internal thoracic artery (ITA), radial artery (RA), and great saphenous vein (GSV) – to bypass stenosed regions of coronary arteries. While decades of research and clinical improvements have made CABG an indispensable procedure, tens of thousands of grafts fail each year, which is due, at least in part, to an inability of the source vessels to adapt to the altered stimuli of the coronary circulation. In this dissertation, we first quantify and compare the mechanical deviation experienced ...


Matrix Stiffness Modulates Mesenchymal Stem Cell Sensitivity To Geometric Asymmetry Signals, Maria Eugenia Piroli Jan 2018

Matrix Stiffness Modulates Mesenchymal Stem Cell Sensitivity To Geometric Asymmetry Signals, Maria Eugenia Piroli

Theses and Dissertations

Human stem cells hold significant potential for the treatment of various diseases. However, their use as a therapy is hampered by the limited understanding of the mechanisms by which stem cells respond to environmental stimuli. Efforts to understand extracellular biophysical cues have demonstrated the critical roles of geometric and mechanical signals in determining the fate of stem cells. The goal of this study was to explore the interplay between cell polarity and matrix stiffness in stem cell lineage specification. We hypothesize that confining cells to asymmetric extracellular matrix (ECM) islands will impart polarity at a single-cell level and result in ...


Plants As Biofactories To Produce Mammalian Tumor Suppressor Micrornas, John Lachlan Macarthur Jan 2018

Plants As Biofactories To Produce Mammalian Tumor Suppressor Micrornas, John Lachlan Macarthur

Theses and Dissertations

MicroRNAs (miRNAs) are small noncoding single stranded RNAs that are considered master regulators of gene expression. They are also an emerging class of therapeutic agents with significant potential for the prevention and treatment of many diseases, including cancer. Many different forms of cancer are associated with loss or reduced accumulation of one or more miRNAs that function as tumor suppressors. In animal models, restoration of missing tumor suppressor miRNAs prevents the initiation, progression and/or spread of the disease. However, the current absence of an efficient method for delivery of therapeutic miRNAs is a critical barrier to their use. The ...


Nondestructive Evaluation Of Corrosion Damage In Reinforced Concrete Aged Slab Specimen, Rawya Abdulsattar Abduljabbar Jan 2018

Nondestructive Evaluation Of Corrosion Damage In Reinforced Concrete Aged Slab Specimen, Rawya Abdulsattar Abduljabbar

Theses and Dissertations

The deterioration of concrete bridge decks presents a maintenance challenge for most transportation agencies and bridge owners. This problem increases during the freeze-thaw cycle. De-icing salts can accelerate the deterioration process. Corrosion of steel reinforcement in reinforced concrete structures is considered a dominant factor causing premature deterioration, especially those structures located in a coastal environment. The resulting corrosion product produced has several times the volume of steel, resulting in cracking of the concrete cover if the corrosion is significant. In this study, a bridge deck specimen was subjected to an artificial environment to accelerate the corrosion process. Prior to this ...


Social Engineering Knowledge Measured As A Security Countermeasure, Christopher Artejus Sanders Jan 2018

Social Engineering Knowledge Measured As A Security Countermeasure, Christopher Artejus Sanders

Theses and Dissertations

Social Engineering has become a significant threat to the security of business, government, and academic institutions. As vulnerabilities to social engineering attacks increase, organizations must incorporate risk mitigation strategies to their portfolios of Information Systems Security Countermeasures (ISSC). The goal is to implement mitigation strategies that balance the cost of implementation, the privacy of employees, and the resulting expected costs of social engineering attacks. In this paper we develop an analytical model that calculates the total cost of protection, including the trade-off between the cost of implementing protection strategies and the resulting expected cost of social engineering attacks. We use ...


Meso-Scale Simulation Of Size-Dependent Shear Behavior In Glass Fiber Reinforced Polymer Reinforced Concrete Beams Without Stirrups, Sina Khodaie Jan 2018

Meso-Scale Simulation Of Size-Dependent Shear Behavior In Glass Fiber Reinforced Polymer Reinforced Concrete Beams Without Stirrups, Sina Khodaie

Theses and Dissertations

There is extensive experimental evidence of the decrease in the shear stress at failure at increasing effective depths in concrete beams reinforced with glass fiberreinforced polymer (GFRP) bars without shear reinforcement. An important practical implication is that extrapolating strength values from typical laboratory-scaled experiments to design larger members may be misleading. The complexity of the underlying mechanics is reflected in the difficulty of using commercially available numerical tools to accurately estimate shear strength irrespective of beam size. This dissertation presents research on a Lattice Discrete Particle Model (LDPM) based model to simulate the response of scaled slender GFRP reinforced concrete ...


Authenticating Users With 3d Passwords Captured By Motion Sensors, Jing Tian Jan 2018

Authenticating Users With 3d Passwords Captured By Motion Sensors, Jing Tian

Theses and Dissertations

Authentication plays a key role in securing various resources including corporate facilities or electronic assets. As the most used authentication scheme, knowledgebased authentication is easy to use but its security is bounded by how much a user can remember. Biometrics-based authentication requires no memorization but ‘resetting’ a biometric password may not always be possible. Thus, we propose study several behavioral biometrics (i.e., mid-air gestures) for authentication which does not have the same privacy or availability concerns as of physiological biometrics.

In this dissertation, we first propose a user-friendly authentication system Kin- Write that allows users to choose arbitrary, short ...


Modulation Of Amyloid-Β Aggregation Via Small Molecules And Glycine Zipper Alterations, Steven Zebulon Vance Jan 2018

Modulation Of Amyloid-Β Aggregation Via Small Molecules And Glycine Zipper Alterations, Steven Zebulon Vance

Theses and Dissertations

Alzheimer’s disease (AD) is the most common form of neurodegenerative disease. Nationally, AD is the 6th leading cause of death and the only top 10 killer of Americans that cannot be slowed, cured, or prevented. AD is characterized by the deposition of extracellular plaques of aggregated amyloid-β protein (Aβ). Aβ originates from the amyloid precursor protein (APP), a transmembrane protein that is cleaved to form a short and inert protein fragment called Aβ. However, Aβ undergoes a nucleation process wherein aggregates from soluble oligomers to insoluble fibrils are formed. While uncertainty remains as to the exact mechanism, studies have ...


Evaluation Of Sonocatalytic Degradation Of Ibuprofen And Sulfamethoxazole In The Presence Of Various Catalysts, Yasir Alhamadani Jan 2018

Evaluation Of Sonocatalytic Degradation Of Ibuprofen And Sulfamethoxazole In The Presence Of Various Catalysts, Yasir Alhamadani

Theses and Dissertations

Over the last two decades, large quantities of products, such as medicines, disinfectants, and personal care products, have been released into surface waters and wastewater treatment facilities by the pharmaceutical and chemical industries which have come to the attention of scientists with regard to their impacts on life in lakes, rivers, and groundwater. Among various types of treatment processes, ultrasonic (US) treatment process was used in this study to investigate the effect catalysts and removal of selected pharmaceutical’s (PhACs) compounds (ibuprofen (IBP) and sulfamethoxazole (SMX)). Carbon nanomaterials (CNMs) have become candidates for numerous applications in nanocomposites, microelectric devices, sensors ...


The Effects Of Joule Heating On Electric-Driven Microfluidic Flow, Alexander P. Spitzer Nov 2017

The Effects Of Joule Heating On Electric-Driven Microfluidic Flow, Alexander P. Spitzer

Journal of the South Carolina Academy of Science

This study sought out to more clearly understand the relationship between Joule heating and fluid flow in microfluidic environments, and more specifically, under what circumstances would the fluid flow in the device possibly hinder an experiment being run on it. It had been previous theorised that an electric field may produce turbulence and even vortices within the fluid, which this study attempted to reproduce. Several variables were tested, namely insulating and conducting fluids, higher and lower AC voltages, Newtonian vs. non-Newtonian fluids, and higher and lower DC voltages. A correlation between these variables and turbulent flow was found, with more ...