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Full-Text Articles in Engineering
Fabrication Of 3d Ultrafine Fibrous Protein Structures Via Freeze-Drying, Yiling Huang
Fabrication Of 3d Ultrafine Fibrous Protein Structures Via Freeze-Drying, Yiling Huang
Department of Textiles, Merchandising, and Fashion Design: Dissertations, Theses, and Student Research
In this thesis, ultrafine fibrous 3D matrices were fabricated using three different proteins (soy protein, wool keratin, and chicken feather keratin) via freeze-drying. Protein matrices are preferable for tissue engineering compared to matrices made from synthetic material because of their similarity to native extracellular matrices. Due to their cell-binding motifs, natural proteins are also recognized as more biocompatible compared. Freeze-drying, which is a simple method used to produce 3D sponge matrices, was employed in this study to fabricate 3D fibrous matrices in a controlled manner. The inner structures of the 3D matrices fabricated ranged from film to fibers, and the …
Electrospun Plant Protein Scaffolds With Fibers Oriented Randomly And Evenly In Three-Dimensions For Soft Tissue Engineering Applications, Shaobo Cai
Department of Textiles, Merchandising, and Fashion Design: Dissertations, Theses, and Student Research
In this work, electrospinnable and water stable soyprotein was extracted by using a reducing agent in mild alkaline condition, and novel 3D zein and 3D pure soyprotein electrospun scaffolds with three-dimensionally and randomly oriented fibers and large interconnected pores were successfully fabricated by reducing surface resistivity of materials. This unique structure is different from most electrospun scaffolds with fibers oriented mainly in one direction. The structure of novel 3D scaffolds could more closely mimic the 3D randomly oriented fibrous architectures in many native extracellular matrixes (ECM). Confocal laser scanning microscope shows that instead of becoming flattened cells when cultured in …