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Full-Text Articles in Engineering
Near-Field Electrospinning Of A Polymer/Bioactive Glass Composite To Fabricate 3d Biomimetic Structures, Krishna C. R. Kolan, Jie Li, Sonya Roberts, Julie A. Semon, Jonghyun Park, D. E. Day, Ming-Chuan Leu
Near-Field Electrospinning Of A Polymer/Bioactive Glass Composite To Fabricate 3d Biomimetic Structures, Krishna C. R. Kolan, Jie Li, Sonya Roberts, Julie A. Semon, Jonghyun Park, D. E. Day, Ming-Chuan Leu
Biological Sciences Faculty Research & Creative Works
Bioactive glasses have recently gained attention in tissue engineering and three-dimensional (3D) bioprinting because of their ability to enhance angiogenesis. Some challenges for developing biological tissues with bioactive glasses include incorporation of glass particles and achieving a 3D architecture mimicking natural tissues. In this study, we investigate the fabrication of scaffolds with a polymer/bioactive glass composite using near-field electrospinning (NFES). An overall controlled 3D scaffold with pores, containing random fibers, is created and aimed to provide superior cell proliferation. Highly angiogenic borate bioactive glass (13-93B3) in 20 wt.% is added to polycaprolactone (PCL) to fabricate scaffolds using the NFES technique. …