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Full-Text Articles in Engineering
Effects Of Local Ph On The Formation And Regulation Of Cristae Morphologies, Dong Hoon Song, Jonghyun Park, Martin A. Philbert, Ann Marie Sastry, Wei Lu
Effects Of Local Ph On The Formation And Regulation Of Cristae Morphologies, Dong Hoon Song, Jonghyun Park, Martin A. Philbert, Ann Marie Sastry, Wei Lu
Mechanical and Aerospace Engineering Faculty Research & Creative Works
Cristae, folded subcompartments of the inner mitochondrial membrane (IMM), have complex and dynamic morphologies. Since cristae are the major site of adenosine triphosphate synthesis, morphological changes of cristae have been studied in relation to functional states of mitochondria. In this sense, investigating the functional and structural significance of cristae may be critical for understanding progressive mitochondrial dysfunction. However, the detailed mechanisms of the formation and regulation of these cristae structures have not been fully elucidated. Among the hypotheses concerning the regulation of cristae morphologies, we exclusively investigate the effects of the local pH gradient on the cristae morphologies by using …
An Investigation Of The Effect Of Direct Metal Deposition Parameters On The Characteristics Of The Deposited Layers, Tarak A. Amine, Joseph William Newkirk, Frank W. Liou
An Investigation Of The Effect Of Direct Metal Deposition Parameters On The Characteristics Of The Deposited Layers, Tarak A. Amine, Joseph William Newkirk, Frank W. Liou
Materials Science and Engineering Faculty Research & Creative Works
Multilayer direct laser deposition (DLD) is a fabrication process through which parts are fabricated by creating a molten pool into which metal powder is injected as particles. During fabrication, complex thermal activity occurs in different regions of the build; for example, newly deposited layers will reheat previously deposited layers. The objective of this study was to provide insight into the thermal activity that occurs during the DLD process. This work focused on the effect of the laser parameters of newly deposited layers on the microstructure and mechanical properties of the previously deposited layers in order to characterize these effects to …