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Articles 1 - 5 of 5

Full-Text Articles in Engineering

Cgmp Recombinant Fix For Iv And Oral Hemophilia B Therapy, William H. Velander Principal Investigator, Abramson Stephan Lead Investigator, Cooper Julian Lead Investigator, William Dernell Key Person, Mark Manning Lead Investigator, Michael Meagher Lead Investigator, Paul Mohanan Lead Investigator, Timothy Nichols Lead Investigator, Todd Swaanson Key Person, Kevin E. Van Cott Sep 2005

Cgmp Recombinant Fix For Iv And Oral Hemophilia B Therapy, William H. Velander Principal Investigator, Abramson Stephan Lead Investigator, Cooper Julian Lead Investigator, William Dernell Key Person, Mark Manning Lead Investigator, Michael Meagher Lead Investigator, Paul Mohanan Lead Investigator, Timothy Nichols Lead Investigator, Todd Swaanson Key Person, Kevin E. Van Cott

Department of Chemical and Biomolecular Engineering: Funded Proposals

Three specific aims are proposed: Specific Aim # 1. Process engineer and scale-up the recovery and purification of transgenic recombinant human Factor IX. The University of Nebraska-Lincoln Biological Process Development Facility will complete process development and scale-up, and produce clinical grade materials for preclinical studies. The endpoint is a proposed final product specification to help facilitate transfer to current Good Manufacturing Practices compliant production of clinical grade material to support an Investigational New Drug filing with the United States Food and Drug Administration (FDA) leading to clinical trials. Specific Aim #2. Characterize and formulate transgenic recombinant human Factor IX for …


Development Of A Steel Bridge System - Simple For Dead Load And Continuous For Live Load, Atorod Azizinamini, Aaron Jon Yakel, Mohammadreza Farimani Jul 2005

Development Of A Steel Bridge System - Simple For Dead Load And Continuous For Live Load, Atorod Azizinamini, Aaron Jon Yakel, Mohammadreza Farimani

Nebraska Department of Transportation: Research Reports

No abstract provided.


Modeling Interface Failure In Fiber-Composites, Andrew J. Craig May 2005

Modeling Interface Failure In Fiber-Composites, Andrew J. Craig

Honors Capstone Projects - All

Interface failure has been studied in depth for more than the past twenty years due to its significant impact on the application of composite materials. The objective of this work is to investigate the role of the interface in the mechanical response of fiber-matrix composite materials subjected to an applied load. To do this, a single composite cylinder consisting of a rigid core, the fiber, and an elastic annulus, the matrix, with an interface of vanishing thickness separating them, is considered as the first step in what will later be representative of a composite material. Three non-linear, Needleman-type, force-separation relations …


Effects Of Central Island Landscape Treatments At Single-Lane Roundabouts, Karen Schurr, Jorge Abos-Sanchez Mar 2005

Effects Of Central Island Landscape Treatments At Single-Lane Roundabouts, Karen Schurr, Jorge Abos-Sanchez

Nebraska Department of Transportation: Research Reports

No abstract provided.


Assessment Of Aquifer Vulnerability Due To Heavy Metals Using Ordinal Logistic Regression Analysis, N. K. Twarakavi, Jagath J. Kaluarachchi Mar 2005

Assessment Of Aquifer Vulnerability Due To Heavy Metals Using Ordinal Logistic Regression Analysis, N. K. Twarakavi, Jagath J. Kaluarachchi

Civil and Environmental Engineering Faculty Publications

A methodology using ordinal logistic regression is proposed to predict the probability of occurrence of heavy metals in ground water. The predicted probabilities are defined with reference to the background concentration and the maximum contaminant level. The model is able to predict the occurrence due to different influencing variables such as the land use, soil hydrologic group (SHG), and surface elevation. The methodology was applied to the Sumas-Blaine Aquifer located in Washington State to predict the occurrence of five heavy metals. The influencing variables considered were (1) SHG; (2) land use; (3) elevation; (4) clay content; (5) hydraulic conductivity; and …