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Developing An Optomechanical Approach For Characterizing Mechanical Properties Of Single Adherent Cells, Ali Mehrnezhad
Developing An Optomechanical Approach For Characterizing Mechanical Properties Of Single Adherent Cells, Ali Mehrnezhad
LSU Doctoral Dissertations
Mechanical properties of a cell reflect its biological and pathological conditions including cellular disorders and fundamental cellular processes such as cell division and differentiation. There have been active research efforts to develop high-throughput platforms to mechanically characterize single cells. Yet, many of these research efforts are focused on suspended cells and use a flow-through configuration. Therefore, adherent cells are detached prior to the characterization, which seriously perturbs the cellular conditions. Also, methods for adherent cells are limited in their throughput.
My study is aimed to fill the technical gap in the field of single cell analysis, which is a high-throughput …