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Electrospun Plant Protein Scaffolds With Fibers Oriented Randomly And Evenly In Three-Dimensions For Soft Tissue Engineering Applications, Shaobo Cai
Department of Textiles, Merchandising, and Fashion Design: Dissertations, Theses, and Student Research
In this work, electrospinnable and water stable soyprotein was extracted by using a reducing agent in mild alkaline condition, and novel 3D zein and 3D pure soyprotein electrospun scaffolds with three-dimensionally and randomly oriented fibers and large interconnected pores were successfully fabricated by reducing surface resistivity of materials. This unique structure is different from most electrospun scaffolds with fibers oriented mainly in one direction. The structure of novel 3D scaffolds could more closely mimic the 3D randomly oriented fibrous architectures in many native extracellular matrixes (ECM). Confocal laser scanning microscope shows that instead of becoming flattened cells when cultured in …