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Full-Text Articles in Education

Investigation Of Gamma-Aminobutyric Acid (Gaba) A Receptors Genes And Migraine Susceptibility, Francesca Fernandez, Teresa Esposito, Rod Lea, Natalie Colson, Alfredo Ciccodicola, Fernando Gianfrancesco, Lyn Griffiths Jan 2008

Investigation Of Gamma-Aminobutyric Acid (Gaba) A Receptors Genes And Migraine Susceptibility, Francesca Fernandez, Teresa Esposito, Rod Lea, Natalie Colson, Alfredo Ciccodicola, Fernando Gianfrancesco, Lyn Griffiths

Faculty of Social Sciences - Papers (Archive)

BACKGROUND: Migraine is a neurological disorder characterized by recurrent attacks of severe headache, affecting around 12% of Caucasian populations. It is well known that migraine has a strong genetic component, although the number and type of genes involved is still unclear. Prior linkage studies have reported mapping of a migraine gene to chromosome Xq 24-28, a region containing a cluster of genes for GABA A receptors (GABRE, GABRA3, GABRQ), which are potential candidate genes for migraine. The GABA neurotransmitter has been implicated in migraine pathophysiology previously; however its exact role has not yet been established, although GABA receptors agonists have …


Large Manual Pointing Errors, But Accurate Verbal Reports, For Indications Of Target Azimuth, John W. Philbeck, Jesse Sargent, Joeanna C. Arthur, Stephen Dopkins Jan 2008

Large Manual Pointing Errors, But Accurate Verbal Reports, For Indications Of Target Azimuth, John W. Philbeck, Jesse Sargent, Joeanna C. Arthur, Stephen Dopkins

Faculty of Social Sciences - Papers (Archive)

Many tasks have been used to probe human directional knowledge, but relatively little is known about the comparative merits of different means of indicating target azimuth. Few studies have compared action-based versus non-action-based judgments for targets encircling the observer. This comparison promises to illuminate not only the perception of azimuths in the front and rear hemispaces, but also the frames of reference underlying various azimuth judgments, and ultimately their neural underpinnings. We compared a response in which participants aimed a pointer at a nearby target, with verbal azimuth estimates. Target locations were distributed between 20° and 340°. Non-visual pointing responses …


Positive Association Between Plasma Homocysteine Level And Chronic Kidney Disease, Anoop Shankar, Jie Wang, Brian Chua, Elena Rochtchina, Victoria Flood, Paul Mitchell Jan 2008

Positive Association Between Plasma Homocysteine Level And Chronic Kidney Disease, Anoop Shankar, Jie Wang, Brian Chua, Elena Rochtchina, Victoria Flood, Paul Mitchell

Faculty of Social Sciences - Papers (Archive)

BACKGROUND:

Increasing experimental evidence, including recently developed animal models, supports a role for homocysteine in the development of chronic kidney disease (CKD). However, relatively few clinical/epidemiological studies have examined this hypothesis in humans. We examined the relationship between plasma homocysteine level and CKD in a population-based study of older Australians.

METHODS:

Community-based study (1992-1994) among 2,609 individuals (58.6% women), aged 49-98 years, free of clinical cardiovascular disease in the Blue Mountains region, west of Sydney, Australia. The main outcome-of-interest was CKD (n = 461), defined as estimated glomerular filtration rate of <60 ml/min/1.73 m(2).

RESULTS:

Higher plasma homocysteine levels were positively associated with …


Investigation Between The S377g3 Gata-4 Polymorphism And Migraine, Sherin Chikhani, Francesca Fernandez, Karl Poetter, Brendam Toohey, Ron Harvey, Lyn Griffiths Jan 2008

Investigation Between The S377g3 Gata-4 Polymorphism And Migraine, Sherin Chikhani, Francesca Fernandez, Karl Poetter, Brendam Toohey, Ron Harvey, Lyn Griffiths

Faculty of Social Sciences - Papers (Archive)

Migraine is a common and painful neurological disorder, with genetic and environmental components. Several conditions have been shown to be comorbid with migraine, notably a cardiac malformation affecting the interatrial septum and leading to patent foramen ovale (PFO). Mutations in the development regulatory gene GATA-4, located on human chromosome 8p23.1-p22, have been found to be responsible for some cases of congenital heart defects including PFO. To determine whether the GATA-4 gene is involved in migraine, the present study performed an association analysis of a common GATA-4 variant that results in a change of amino acid (S377G), in a large …


Beta-Glucans In The Treatment Of Diabetes And Associated Cardiovascular Risks, Jiezhong Chen, Kenneth Raymond Jan 2008

Beta-Glucans In The Treatment Of Diabetes And Associated Cardiovascular Risks, Jiezhong Chen, Kenneth Raymond

Faculty of Social Sciences - Papers (Archive)

Diabetes mellitus is characterized by high blood glucose level with typical manifestations of thirst, polyuria, polydipsia, and weight loss. It is caused by defects in insulin-mediated signal pathways, resulting in decreased glucose transportation from blood into muscle and fat cells. The major risk is vascular injury leading to heart disease, which is accelerated by increased lipid levels and hypertension. Management of diabetes includes: control of blood glucose level and lipids; and reduction of hypertension. Dietary intake of beta-glucans has been shown to reduce all these risk factors to benefit the treatment of diabetes and associated complications. In addition, beta-glucans also …


Visuospatial Memory Deficits In Long Term Heavy Cannabis Users: Relation To Psychotic Symptoms And Regional Brain Volumes, Nadia Solowij, Colleen Respondek, Robert A. Battisti, Sarah Whittle, Daniel Dr Daniel Lubman, Murat Yucel Jan 2008

Visuospatial Memory Deficits In Long Term Heavy Cannabis Users: Relation To Psychotic Symptoms And Regional Brain Volumes, Nadia Solowij, Colleen Respondek, Robert A. Battisti, Sarah Whittle, Daniel Dr Daniel Lubman, Murat Yucel

Faculty of Social Sciences - Papers (Archive)

Abstract from the XXVI CINP Congress, Munich, 13-17 July 2008


Increased Suicide Risk In Depressed Patients Predicted By Long-Chain Fatty Acids, Nadia Solowij, Brin F. S Grenyer, Barbara J. Meyer, P Howe Jan 2008

Increased Suicide Risk In Depressed Patients Predicted By Long-Chain Fatty Acids, Nadia Solowij, Brin F. S Grenyer, Barbara J. Meyer, P Howe

Faculty of Social Sciences - Papers (Archive)

bstract from the XXVI CINP Congress, Munich, 13-17 July 2008


Environmental Modulation Of Phenotype In Neuregulin 1 Mutants, Tim Karl, A. Boucher, Brian Dean, Xu-Feng Huang, J Arnold, P. Schofield Jan 2008

Environmental Modulation Of Phenotype In Neuregulin 1 Mutants, Tim Karl, A. Boucher, Brian Dean, Xu-Feng Huang, J Arnold, P. Schofield

Faculty of Social Sciences - Papers (Archive)

Abstract from the XXVI CINP Congress, Munich, Germany, 13-17 July 2008


"They All Work...When You Stick To Them": A Qualitative Investigation Of Dieting, Weight Loss, And Physical Exercise, In Obese Individuals, Samantha L. Thomas, Jim Hyde, Asuntha Karunaratne, Rick Kausman, Paul Komesaroff Jan 2008

"They All Work...When You Stick To Them": A Qualitative Investigation Of Dieting, Weight Loss, And Physical Exercise, In Obese Individuals, Samantha L. Thomas, Jim Hyde, Asuntha Karunaratne, Rick Kausman, Paul Komesaroff

Faculty of Social Sciences - Papers (Archive)

Background To explore the extent to which people living with obesity have attempted to lose weight, their attitudes towards dieting, physical exercise and weight loss solutions, why their weight loss attempts have failed, and their opinions about what would be most beneficial to them in their struggle with their weight. Method Qualitative study, using open-ended interviews, of 76 people living with obesity in Victoria, Australia in 2006/7. Individuals with a BMI of 30 or over were recruited using articles in local newspapers, convenience sampling, and at a later stage purposive sampling techniques to diversify the sample. Data analysis was conducted …


Effects Of Fully-Established Sure Start Local Programmes On 3-Year-Old Children And Their Families Living In England: A Quasi-Experimental Observational Study, Edward Melhuish, Jay Belsky, Alastair H. Leyland, Jacqueline Barnes Jan 2008

Effects Of Fully-Established Sure Start Local Programmes On 3-Year-Old Children And Their Families Living In England: A Quasi-Experimental Observational Study, Edward Melhuish, Jay Belsky, Alastair H. Leyland, Jacqueline Barnes

Faculty of Social Sciences - Papers (Archive)

Background

Sure Start Local Programmes (SSLPs) are area-based interventions to improve services for young children and their families in deprived communities, promote health and development, and reduce inequalities. We therefore investigated whether SSLPs affect the wellbeing of 3-year-old children and their families.

Methods

In a quasi-experimental observational study, we compared 5883 3-year-old children and their families from 93 disadvantaged SSLP areas with 1879 3-year-old children and their families from 72 similarly deprived areas in England who took part in the Millennium Cohort Study. We studied 14 outcomes—children's immunisations, accidents, language development, positive and negative social behaviours, and independence; parenting risk; …


Research And Policy In Developing An Early Years' Initiative: The Case Of Sure Start, Jay Belsky, Edward Melhuish, Jacqueline Barnes Jan 2008

Research And Policy In Developing An Early Years' Initiative: The Case Of Sure Start, Jay Belsky, Edward Melhuish, Jacqueline Barnes

Faculty of Social Sciences - Papers (Archive)

The British government's wish to eliminate the cycle of disadvantage for children from poor families led to Sure Start. The initiative set up 260 Sure Start Local Programmes (SSLPs) by 2001, which were expanded to 524 programmes within 2 years. SSLPs aimed to enhance the health and development of children under four and their families in deprived communities. SSLPs were area-based, with all children under four and their families in an area being eligible. This allowed efficient delivery of services without stigmatisation. SSLPs did not have a prescribed "protocol" of services. Instead, each SSLP had autonomy to improve and create …


Influencing Policy And Practice Through Research On Early Childhood Education, Brenda Taggart, Iram Siraj-Blatchford, Kathy Sylva, Edward Melhuish, Pam Sammons Jan 2008

Influencing Policy And Practice Through Research On Early Childhood Education, Brenda Taggart, Iram Siraj-Blatchford, Kathy Sylva, Edward Melhuish, Pam Sammons

Faculty of Social Sciences - Papers (Archive)

This paper presents the scientific evidence from one study that has informed Early Years policy in the U.K. It begins with a description of the policy context in the early 1990s and shows how research was used to inform a decade of policy innovation. There have been many studies of ways that research has informed practice but fewer on instances of research shaping policy. This paper is one step in that direction, as advocated by Whitty (2007) and Huw, Nutley and Smith (2001).


An Investigation Of The Relationship Between Financial Capability And Psychological Well-Being In Mothers Of Young Children In Poor Areas In England, Edward Melhuish, Jay Belsky, Antero Malin Jan 2008

An Investigation Of The Relationship Between Financial Capability And Psychological Well-Being In Mothers Of Young Children In Poor Areas In England, Edward Melhuish, Jay Belsky, Antero Malin

Faculty of Social Sciences - Papers (Archive)

Financial difficulties lead to financial distress that in turn may lead to poorer psychological well-being. Previous work on people's financial difficulties and capability indicates that those most vulnerable to financial difficulties may well suffer with regard to their psychological state. One particularly vulnerable group are families with young children in disadvantaged areas.


Understanding The Relationship Between Curriculum, Pedagogy And Progression In Learning In Early Childhood, Iram Siraj-Blatchford Jan 2008

Understanding The Relationship Between Curriculum, Pedagogy And Progression In Learning In Early Childhood, Iram Siraj-Blatchford

Faculty of Social Sciences - Papers (Archive)

This paper provides mutually reinforcing definitions for the terms 'Curriculum' and 'Pedagogy' are applied in an attempt to provide further clarification of the learning processes involved in 'Co-construction' and 'Sustained Shared Thinking'. The implications for pedagogic progression and for understanding early childhood practices are also identified. The theoretical model is then applied in support of the English Early Years Foundation Stage against charges of inappropriate 'schoolification '. The paper also provides in outline a new typology of early childhood educational practices.


Field Observations And Empirical Research, Koko Warner, Olivia V. Dun, Marc Stal Jan 2008

Field Observations And Empirical Research, Koko Warner, Olivia V. Dun, Marc Stal

Faculty of Social Sciences - Papers (Archive)

The Environmental Change and Forced Migration Scenarios (EACH-FOR) project is a systematic attempt to detect the degree to which, and the pathways through which, environmental stressors affect migration.


The Big Fish Strikes Again But In A Different Place: Social Comparison Theory And Children With Special Needs, Roselyn May Dixon, Marjorie Seaton, Robert John Dixon Jan 2008

The Big Fish Strikes Again But In A Different Place: Social Comparison Theory And Children With Special Needs, Roselyn May Dixon, Marjorie Seaton, Robert John Dixon

Faculty of Social Sciences - Papers (Archive)

This paper will address the implications of Big-Fish Little Pond Effect (BFLPE) and social comparison theory and school placement of students with special needs. It made use of the PISA data base to determine if type of educational placement had an impact on the academic self-concept with children with special needs. Multiple regression techniques were used to delineate the relationships.


Canines, Consanguinity, And One-Medicine: All The Qualities Of A Dog Except Loyalty, Christopher J. Degeling Jan 2008

Canines, Consanguinity, And One-Medicine: All The Qualities Of A Dog Except Loyalty, Christopher J. Degeling

Faculty of Social Sciences - Papers (Archive)

The rise of pet culture and the expansion of medical science occurred concurrently in the late nineteenth century. From this time in Anglo-American societies dogs were simultaneously valorised as 'man's best friend' and the 'ideal model' for experimental medicine. By tracking the hounds into our laboratories and onto the settee, changes in our conception of the properties of blood and canine breeding can be used to excavate covert connections between the contradictory social and scientific utilisations of this species. Describing the movement of genealogical and medical knowledge between the benchtop, the kennel and the clinic illustrates how Rudolph Virchow's earlier …


Threats To Kill: A Follow-Up Study, L J. Warren, P E. Mullen, S Dm Thomas, J Rp Ogloff, P M. Burgess Jan 2008

Threats To Kill: A Follow-Up Study, L J. Warren, P E. Mullen, S Dm Thomas, J Rp Ogloff, P M. Burgess

Faculty of Social Sciences - Papers (Archive)

Background Mental health clinicians are frequently asked to assess the risks presented by patients making threats to kill, but there are almost no data to guide such an evaluation. Method This data linkage study examined serious violence following making threats to kill and the potential role of mental disorder. A total of 613 individuals convicted of threats to kill had their prior contact with public mental health services established at the time of the index offence. The group's subsequent criminal convictions were established 10 years later using the police database. Death from suicidal or homicidal violence was also established. Results …