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Genetic And Environmental Interactions On Schizophrenia-Like Phenotypes In Chl1 Deficient Mice, J. Daniel Obray

Undergraduate Honors Capstone Projects

Schizophrenia is a debilitating disorder which is often characterized by dysregulation of the processing of sensory information. Schizophrenia has been shown to have a strong genetic component, as well as a strong environmental component. As such, a number of hypotheses such as the diathesis stress hypothesis have been developed to explain the etiology of schizophrenia. As most of these theories attempt to account for a genetic and an environmental factor, they are often viewed as double-hit models of schizophrenia. Several theories have emerged as potential explanations for the symptoms of schizophrenia. The dopamine hypothesis suggests that the basal level of …