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Life Sciences

1993

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Diagnosis Of Naturally Acquired Type-I And Type-Ii Diabetes Mellitus In Cats, Claudia Kirk, E Feldman, R Nelson Feb 1993

Diagnosis Of Naturally Acquired Type-I And Type-Ii Diabetes Mellitus In Cats, Claudia Kirk, E Feldman, R Nelson

Claudia A Kirk

After IV administration of 0.5 mg of glucagon/cat, glucose tolerance and insulin secretory response were evaluated in 10 lean cats, 10 obese cats, and 30 cats with diabetes mellitus. Blood samples for glucose and insulin determinations were collected immediately before and at 5, 10, 15, 30, 45, and 60 minutes after IV administration of glucagon. Baseline serum insulin concentration and insulin secretory response were used to classify diabetes mellitus in the 30 cats as type I or type II. Mean (+/- SEM) baseline and 30-minute serum glucose concentrations in obese cats were significantly (P < 0.05) decreased, compared with ...