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Life Sciences

1991

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Intracavitary Cisplatin Chemotherapy Experience With Six Dogs, A Moore, Claudia Kirk, A Cardona Dec 1990

Intracavitary Cisplatin Chemotherapy Experience With Six Dogs, A Moore, Claudia Kirk, A Cardona

Claudia A Kirk

Six dogs with a median age of 7 years (range = 5-14 years) were presented for signs referable to thoracic or abdominal effusion associated with neoplasia of the body cavities. Intracavitary cisplatin was administered at 50 mg/m2 every 4 weeks for a median of 2.5 treatments (mean = 3, range = 1-6). Three dogs with pleural mesothelioma had complete resolution of effusion for 289, 129, and greater than 306 days without evidence of tumor growth. Resolution of effusion occurred after one treatment in two dogs and after two treatments in one dog. In three dogs with carcinomatosis of unknown origin, complete ...