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USF Tampa Graduate Theses and Dissertations

2007

Biosensor

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Full-Text Articles in Arts and Humanities

Cellmap: An Automated Multielectrode Array Cell Culture Analysis System Based On Electrochemical Impedance Spectroscopy, Abdur Rub Abdur Rahman Jun 2007

Cellmap: An Automated Multielectrode Array Cell Culture Analysis System Based On Electrochemical Impedance Spectroscopy, Abdur Rub Abdur Rahman

USF Tampa Graduate Theses and Dissertations

The objective of this research is to develop fundamental understanding of cell-substrate (CS) and cell-cell (CC) interactions in the culture space for time evolving cell cultures. Space resolved CC and CS interactions are important indicators of cell-density distribution, localized cellular behavior, and multiple cell-layers which are differentiators of normal and abnormal cell behavior. In this research, CS and CC interactions and the variations therein due to a) Cell growth, 2) cell-drug interaction, and 3) effect of Cytotoxin were studied using multielectrode, multi-frequency Electrochemical Impedance Spectroscopy (EIS). Contemporary impedance based methods sense either CC or CS interaction as a space averaged …


Synthesis And Characterization Of Interfaces Between Naturally Derived And Synthetic Nanostructures For Biomedical Applications, Souheil Zekri Jun 2007

Synthesis And Characterization Of Interfaces Between Naturally Derived And Synthetic Nanostructures For Biomedical Applications, Souheil Zekri

USF Tampa Graduate Theses and Dissertations

The use of nanotechnology to develop methods for fabrication and characterization of organized hybrid nanostructures that include integrated polymeric, biological and inorganic compounds has increased exponentially during the last decade. Such bio-nano-composite materials could be used in solving current biomedical problems spanning from nanomedicine to tissue engineering and biosensing. In this dissertation, a systematic study has been carried out on the synthesis, characterization, of two interfaces between naturally derived and synthetic nanostructures. Carbon nanotubes and porous silicon represent the synthetic nanostructures that were developed for the purpose of interfacing with the naturally derived bovine type I collagen and respiratory syncytial …


Synthesis, Characterization, And Applications Of Cvd Micro- And Nanocrystalline Diamond Thin Films, Zhenqing Xu Jun 2007

Synthesis, Characterization, And Applications Of Cvd Micro- And Nanocrystalline Diamond Thin Films, Zhenqing Xu

USF Tampa Graduate Theses and Dissertations

In this thesis, a systematic study has been carried out on the synthesis, characterization and applications of microcrystalline diamond (MCD) and nanocrystalline diamond (NCD) thin films deposited by the chemical vapor deposition (CVD) method. Firstly, an overview of diamond films synthesized from carbon-containing gas plasmas is presented. A parameter study was performed to grow diamond thin films. The transition from micro- to nanocrystallinity of diamond grains was achieved by controlling the Ar/Hydrogen gas ratio. The nanocrystallinity is the result of a new growth mechanism which involves the insertion of carbon dimmer into carbon-carbon and carbon-hydrogen bonds. Secondly, characterization of diamond …