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Full-Text Articles in Arts and Humanities

Intimate Partner Violence: Early Adverse Experiences In Male Offenders, Maria B. Alcivar-Zuniga Jan 2017

Intimate Partner Violence: Early Adverse Experiences In Male Offenders, Maria B. Alcivar-Zuniga

Graduate Theses and Dissertations

Adverse childhood experiences (ACEs) significantly impact social, behavioral and health problems over the lifetime. Research has found that early exposure to adverse experiences are linked to subsequent long term outcomes such as intimate partner violence (IPV). However, there is relatively limited qualitative research on the early experiences in the lives of intimate partner perpetrators. Therefore, through a life-course theoretical lens, this study aims to understand early lived experiences of IPV perpetrators. A content analysis was performed on interviews with 112 men convicted for domestic violence. From this analysis three interconnected themes emerged: (1) family history of criminality, (2) disrupted relationships ...


Contextual Factors And The Syndemic Of Alcohol Use And Risky Sexual Behaviors Among Men Who Have Sex With Men, Humberto López Castillo Oct 2016

Contextual Factors And The Syndemic Of Alcohol Use And Risky Sexual Behaviors Among Men Who Have Sex With Men, Humberto López Castillo

Graduate Theses and Dissertations

Since the early 1990s with the AIDS pandemic, there has been an increasing interest on the importance of risky sexual behaviors, especially among men who have sex with men (MSM). An important antecedent for these behaviors is alcohol use. Studies consistently show an increased frequency of both alcohol use and risky sexual behaviors in MSM populations. However, to date, there has not been a precise estimate of the effect size in these diverse populations and a consistent way to measure it. More so, the importance of context is often cited as a source of variability, but is rarely measured in ...


Kairos In The Let’S Move! Campaign: Crafting Moments Of Change Through Humanistic Rhetoric, Brittany Betzer Jan 2016

Kairos In The Let’S Move! Campaign: Crafting Moments Of Change Through Humanistic Rhetoric, Brittany Betzer

Graduate Theses and Dissertations

Research has established a concerning upward trend of obesity rates in America. The government, including the United States Department of Agriculture and the United States Department of Health and Human Services, has attempted to change American’s poor eating habits by creating public health guides and by making nutrition information publicly available. Public health guides and initiatives have the potential to influence Americans to change, but it is vital to simultaneously help Americans understand the guidance and convince them to use it in their daily lives. Through close textual analysis of Michelle Obama’s announcement speech for Let’s Move ...


Factors Associated With Treatment Seeking In Automotive Manufacturing, Khin Thingyan Chit Nov 2015

Factors Associated With Treatment Seeking In Automotive Manufacturing, Khin Thingyan Chit

Graduate Theses and Dissertations

Introduction

The prevalence of work-related musculoskeletal disorders is very common. The main objective of the study was to identify any association between the severity of musculoskeletal symptoms and treatment choice by workers in automobile manufacturing plants.

Methods

A cross-sectional study of 1017 production workers in six automobile manufacturing plants was performed. The study included the structured interviews to determine symptoms, preexisting personal risk factors, treatment choices (health care provider or no treatment sought), job strain, and job satisfaction. Nordic style questionnaire for symptoms, Karasek’s Demand Control Model and three job satisfaction questions were used to assign symptom severity, job ...


Religiosity, Spirituality, And Depressive Symptoms In Older Adults In An Active Living Community, Monica D'Adrianne Solomon May 2014

Religiosity, Spirituality, And Depressive Symptoms In Older Adults In An Active Living Community, Monica D'Adrianne Solomon

Graduate Theses and Dissertations

The population of older adults in the United States is steadily rising. The Centers for Disease Control and Prevention (CDC) recently released a call to reduce mental distress in older adults. Research shows that mental distress is associated with depressive symptoms, which are significantly related to many chronic medical conditions, functional impairment, suicide, and all-cause mortality. Depression is a major public health concern. There is an interest in gerontology research on the buffering role of engagement against depressive symptoms such as volunteering, social activities, and religion. Certain religious beliefs and behaviors contribute to maintaining or improving mental health and research ...


Her-Storicizing Baldness: Situating Women's Experiences With Baldness From Skin And Hair Disorders, Kasie Holmes Jan 2014

Her-Storicizing Baldness: Situating Women's Experiences With Baldness From Skin And Hair Disorders, Kasie Holmes

Graduate Theses and Dissertations

A general goal to my study was to promote an inclusive approach to baldness by sharing and centering women's experiences with baldness from skin and hair conditions, such as autoimmune alopecia areata conditions and monilethrix. Specifically, a main goal of my study was to her-storicize the lived experiences of women who are bald from skin and hair conditions by examining medical and cultural discourses surrounding these conditions, femininity, and female baldness. Additionally, my study considers strategies of accommodation and resistance that bald women perform in a given context, space, or time. For instance, I consider the ways participants manage ...


Illness Perceptions Of Polycystic Ovary Syndrome, Elizabeth Baker Jan 2014

Illness Perceptions Of Polycystic Ovary Syndrome, Elizabeth Baker

Graduate Theses and Dissertations

Polycystic ovary syndrome (PCOS) is a chronic illness that affects approximately five million premenopausal women in the United States and is associated with significant cosmetic, reproductive, metabolic, and psychological consequences. Despite its prevalence, few studies have explored the lived experiences and illness perceptions of women living with PCOS. Identifying illness perceptions of women living with (WLW) PCOS is important, because mounting research suggests that a person's perceptions of their chronic illness and its management determine that person's coping behaviors (e.g., adherence, self-management) and, consequently, illness outcomes.

In this dissertation, the Common Sense Model (CSM) is used as ...


"When You Tell Them, Your Secret Is Out There": Experiences Of Sexuality And Intimacy Among Hiv Positive Black Women, Mackenzie Rae Tewell Jan 2013

"When You Tell Them, Your Secret Is Out There": Experiences Of Sexuality And Intimacy Among Hiv Positive Black Women, Mackenzie Rae Tewell

Graduate Theses and Dissertations

HIV/AIDS infections disproportionately impact African Americans within the United States. In 2010, black Americans made up 12 percent of the United States population, yet accounted for 44 percent of new HIV/AIDS infections (Kaiser Family Foundation 2013). The majority of black women (85 percent) are infected with the virus through heterosexual contact, meaning it is critical examine their sexual lives in order to gain insight into this infection within this population (CDC 2011b). Through semi-structured interviews at a Tampa, Florida AIDS service organization, this study presents the experiences of sexuality and intimacy among HIV positive black women. Results demonstrate ...


"Le Tengo Fe" How Do Women's Networks Influence The Health Competence Of Latina Immigrant Mothers Living In A Rural Midwestern State?, Flor De Maria Romero De Slowing Jan 2012

"Le Tengo Fe" How Do Women's Networks Influence The Health Competence Of Latina Immigrant Mothers Living In A Rural Midwestern State?, Flor De Maria Romero De Slowing

Graduate Theses and Dissertations

This study explores how the health competence of Latina immigrant mothers living in rural Iowa is influenced by their social, cultural and human capitals. By exploring the role of women's informal networks in disseminating knowledge and practices related to maintaining family health, this study sheds light on the role of cultural values, gendered knowledge and social cohesion in enhancing health competence of Latina immigrant mothers. This study draws a purposive sample from Rural Families Speak about Health (RFSH), a multi-state study that examines the physical and mental health of ethnically diverse rural families with low incomes and young children ...


A Study Of Potential Risk Factors Of Depression Among Latina Breast Cancer Survivors, Claudia Ximena Aguado Loi Jan 2012

A Study Of Potential Risk Factors Of Depression Among Latina Breast Cancer Survivors, Claudia Ximena Aguado Loi

Graduate Theses and Dissertations

Women with breast cancer commonly experience depression. However, this condition often goes unrecognized, undertreated, and understudied, especially in ethnic minorities. If left untreated, co-existing depression in women with cancer can complicate cancer treatment, lead to poor treatment adherence for both conditions, and decrease survival. These negative consequences are considerably higher among Latinas. With the growing number of Latinos and diversity within the Latino community, the literature has identified the need to disaggregate Latinos by region of origin. Unfortunately, few studies account for these differences and no study to date has examined risk factors of depression among Latinas diagnosed with breast ...


Comparison Of Visual Vs. Microscopic Methods To Detect Blood Splatter From An Intravascular Catheter With Engineered Sharps Injury Protection (Esip), Aiysha R. Ansari Jan 2012

Comparison Of Visual Vs. Microscopic Methods To Detect Blood Splatter From An Intravascular Catheter With Engineered Sharps Injury Protection (Esip), Aiysha R. Ansari

Graduate Theses and Dissertations

Intravascular devices with engineered sharps injury protection (ESIP) are designed to reduce sharps injuries, but have not been investigated for blood splatter potential. In this laboratory-based experiment, which did not use human subjects, 100 intravenous catheters of the same type with a retraction mechanism, were tested for blood splatter. Once blood was obtained from a simulated brachial vein containing mock venous blood, the devices were placed in a testing chamber and scientific filters labeled A, B & C were used to capture blood splatter after activation. The blood splatter was examined visually and microscopically, and the filters were weighed pre- and post-activation on an analytical scale. The research questions in this study were: 1) do retractable intravenous devices produce blood splatter, and 2) does blood splatter frequency differ between visual methods vs. microscopy?

The differences in filter mass, visual inspection, and microscopic analysis for presence of blood on filters were the units of analysis. Descriptive statistics, paired t-tests to determine pre and post activation filter weights and kappa statistics to assess degree of agreement between methods were used to analyze the data. For filters B and C, the proportions with blood detected by the naked eye were 12 and 13% respectively. However, for filter A, both visual and microscopic methods detected blood splatter on 70% and 71% of the time respectively. In addition, a statistically significant difference was observed in the mean mass of filter A between pre- and post-activation confirmed by the naked eye (t= - 0.0013, p= 0.01400) and confirmed microscopically (t= - 0.00014, p=0.0092). Substantial agreement between methods was observed for filter A (kappa=0.78; 95% CI: 0.64-0.92), filter B (kappa= 0.73; 95% CI: 0.51-0.95) and filter C (kappa= 0.75; 95% CI: 0 ...


Assessing The Psychometric Properties Of A Self-Efficacy Measure Within A Patient Navigation Research Program, Mariana Arevalo Jan 2012

Assessing The Psychometric Properties Of A Self-Efficacy Measure Within A Patient Navigation Research Program, Mariana Arevalo

Graduate Theses and Dissertations

There is a dearth of validated self-efficacy (SE) measures in the field of preventive oncology. The objective of this study is to describe the development and validation of a measure to assess patients' perceived ability to obtain the recommended care following an abnormality suspicious for breast cancer. Guided by a social cognitive theory framework, a 51-item measure was developed to explore perceived capability to obtain follow up care under a number of barriers. A multi-step process was utilized to assess the instrument's psychometric properties. First, cognitive validity assessments with experts were conducted, and these aided in the wording refinement ...


A Cross-National Analysis Of The Human Papillomavirus, Sexually Transmitted Infections, And Sexual Behavior Among Men, Euna Marie August Jan 2012

A Cross-National Analysis Of The Human Papillomavirus, Sexually Transmitted Infections, And Sexual Behavior Among Men, Euna Marie August

Graduate Theses and Dissertations

There is a paucity of research on the risk for sexually transmitted infections (STIs) and sexual behavior among general populations of men. Research with male populations predominantly has focused on those subgroups considered to be at high risk of disease transmission, such as gay and bisexual men, injection drug users, and adolescents/young adults. Considerably fewer studies have examined factors among men, in general, and heterosexual men, specifically. Therefore, I conducted analyses with a cross-national sample of adult, sexually active men in Brazil, Mexico, and the United States to investigate sexual behaviors and risk factors associated with the human papillomavirus ...


Analysis Of Variable Effects On Presence Of Cryptosporidium Oocysts And Giardia Cysts In Effluent Water From Wastewater Treatment Utilities In Florida From 1998 To 2010, Katherine Jane Barkan Jan 2012

Analysis Of Variable Effects On Presence Of Cryptosporidium Oocysts And Giardia Cysts In Effluent Water From Wastewater Treatment Utilities In Florida From 1998 To 2010, Katherine Jane Barkan

Graduate Theses and Dissertations

The concern of a Cryptosporidium or Giardia waterborne outbreak due to treated wastewater has had water treatment utilities using some of the highest water cleansing technologies available. Cryptosporidiosis and Giardiasis are severe diarrheal diseases which can lead to death, thus it is important that appropriate steps are taken to assure these parasites are not present in the effluent of treated wastewater. This study examined the results of 863 assays for Giardia and Cryptosporidium on the effluent of wastewater treatment facilities and found that county of collection, watershed of collection, and laboratory analyzing the sample have the most significant impact on ...


"People Aren't Mind Readers": A Study Of Sexual Self-Concept, Partner Communication, And Sexual Satisfaction, Heather Blunt Jan 2012

"People Aren't Mind Readers": A Study Of Sexual Self-Concept, Partner Communication, And Sexual Satisfaction, Heather Blunt

Graduate Theses and Dissertations

Sexual health is an important component to overall well-being and quality of life. Yet so much of sexual health research is focused solely on the negative consequences of sexuality, such as unintended pregnancy and transmission of sexually transmitted infections. Recently, the need for a positive, health promotion focused framework for research and understanding sexual health has received attention, including from the World Health Organization and the Centers for Disease Control and Prevention. This transition of public health research and practice from a disease-based framework to a positive, health promotion framework necessitates exploring what factors are associated with positive sexuality and ...


Hurricane Preparedness Of Community-Dwelling Dementia Caregivers In South Florida, Janelle J. Christensen Jan 2012

Hurricane Preparedness Of Community-Dwelling Dementia Caregivers In South Florida, Janelle J. Christensen

Graduate Theses and Dissertations

The aim of this dissertation is to explore how informal caregivers for people with dementia (PWD), who are community dwelling (i.e., not in nursing homes), prepare and plan for disasters. The research site is a particularly hurricane-prone region of Florida, second only to New Orleans in its vulnerability. An underlying assumption of this research is that caregivers for PWD have to plan and anticipate problems that are unique to their role. The rationale for the study described here is that disaster planning and mitigation save lives (Tengs et al. 1995), but there is little or no literature on disaster ...


Critical Heat Stress Evaluation Of Two-Layer Clothing Ensembles And The Contributionof A Full-Face Negative Pressure Respirator, Oclla Michele Fletcher Jan 2012

Critical Heat Stress Evaluation Of Two-Layer Clothing Ensembles And The Contributionof A Full-Face Negative Pressure Respirator, Oclla Michele Fletcher

Graduate Theses and Dissertations

Protective clothing ensembles are worn by workers as a barrier to chemical and physical hazards, but can restrict heat loss and increase worker heat stress. The question of whether a respirator adds to heat stress or strain burden is a continuing concern among occupational health professionals. The purpose of this study was to determine if there are differences in heat stress or strain among the current Toxicological Agent Protective (TAP) ensemble and two ensemble variations used in demilitarization of chemical weapons. Four acclimatized adult males wore five ensembles in a balanced design while walking in a climatic chamber at a ...


Patient Care Provider Safety: Examining One Intervention To Reduce Hospital Violence, Paul Leslie Ford Jan 2012

Patient Care Provider Safety: Examining One Intervention To Reduce Hospital Violence, Paul Leslie Ford

Graduate Theses and Dissertations

Abstract

In the summer of 2009, Tampa General care providers met with Hospital Administration to express concern that violence on care units was a growing problem and making it difficult to provide quality care. Nurses stated that such violence was one important reason many of their peers choose to retire. Administration took this situation seriously and formed a committee to gather information and submit suggestions to reduce the violence. The committee consisted of representatives from several nursing units, human resources, risk management, security, and administration. Duties assigned included investigation of the actual number of reports on all units and trends ...


A Systematic Review Of Interventions To Increase Mental Health Service Use, Jennifer Greene Jan 2012

A Systematic Review Of Interventions To Increase Mental Health Service Use, Jennifer Greene

Graduate Theses and Dissertations

Relatively few pre-treatment interventions to increase out-patient mental health (MH) service use have been created and experimentally tested. Therefore, not only is there limited availability of these interventions, it is uncertain whether existing interventions are effective. Moreover, it is unclear which components of the interventions are effective. To address these gaps in knowledge, a systematic review of pre-treatment interventions was conducted, using the Cochrane Review methodology. Three primary outcomes were evaluated: attendance at any type of out-patient MH visit; number of appointments of any type of out-patient MH visit; and/or initiation and adherence to psychotropic medication. PubMed and PsycINFO ...


Responsiveness Of The Federal Health System To The Needs Of 18-45 Year Old Adults With Physical Disabilities In Islamabad, Pakistan, Shaista Habibullah Jan 2012

Responsiveness Of The Federal Health System To The Needs Of 18-45 Year Old Adults With Physical Disabilities In Islamabad, Pakistan, Shaista Habibullah

Graduate Theses and Dissertations

Abstract

The health system has been defined as all people, institutions and resources that undertake actions with the primary intent of improving health, while responsiveness of the health system refers to its objective of responding to the legitimate expectations of the population it serves. Although responsiveness is a non-health objective of the health system, it affects the health status of the population by influencing treatment compliance, patient-provider communication and health services utilization. Furthermore, responsiveness has a fundamental value as it concerns basic human rights of the individuals being served by the health system.

This study was undertaken to determine how ...


"You Have To Have Children To Be Happy:" Exploring Beliefs About Reproduction With Burmese Refugee Women In The United States, Kara E. Mcginnis Jan 2012

"You Have To Have Children To Be Happy:" Exploring Beliefs About Reproduction With Burmese Refugee Women In The United States, Kara E. Mcginnis

Graduate Theses and Dissertations

Burmese refugees are entering the US at record speed. Resettlement agencies focus on immediate needs, and ethnic community-based organizations (ECBOs) fill any service gaps through community-driven programs. The Tampa Bay Burmese Council (TBBC) is an ECBO in Tampa, FL dedicated to the Burmese community. This research explores the reproductive beliefs of the women in the community, paying particular attention to any differences that arise due to beliefs specific to their ethnic group. Findings include the importance of menses for women's health, the preference for both male and female children, a lack of knowledge about family planning methods, a tendency ...


Evaluation Of Urinary Pesticide Biomarkers Among A Sample Of The Population In The United States, Alex Lance Lebeau Jan 2012

Evaluation Of Urinary Pesticide Biomarkers Among A Sample Of The Population In The United States, Alex Lance Lebeau

Graduate Theses and Dissertations

Pesticide use in the United States continues to attract negative public attention. In recent years, this attention has focused on the effects that chronic, low-level pesticides may have, especially on children and various sub-populations. Over the past decade, studies have attempted to correlate negative health effects with detections of pesticide biomarkers in biological media. The current research investigates biomarker of exposure levels in a sample of the United States population. Data from the 2001-2002 NHANES dataset (n=11,039) was evaluated. The detection frequency of urinary biomarkers of exposure and the geometric mean from the NHANES pesticide dataset (n=3 ...


Relationships Of Heat Stress Levels To Heat-Related Disorders And Acute Injury During Deepwater Horizon Cleanup Operations, Michael H. Hiles Jan 2012

Relationships Of Heat Stress Levels To Heat-Related Disorders And Acute Injury During Deepwater Horizon Cleanup Operations, Michael H. Hiles

Graduate Theses and Dissertations

Outdoor workers are often subjected to thermal conditions beyond the comfort zone, but to what degree do such conditions affect the health and safety of those workers is still a matter requiring further investigation. The purpose of this study is to examine the relationship between thermal conditions and (1) heat-related disorders and (2) acute injuries using injury and illness data collected during the BP Deepwater Horizon clean-up operations. Over an eleven month period, 5,485 cases were identified as either heat-related or an acute injury (incident type) and further divided by severity. Daily weather data were used to estimate the ...


Interrogating Grenadian Masculinities And Violence Against Women: An Evaluation Of The United Nations Partnership For Peace Program, Rohan Dexter Jeremiah Jan 2012

Interrogating Grenadian Masculinities And Violence Against Women: An Evaluation Of The United Nations Partnership For Peace Program, Rohan Dexter Jeremiah

Graduate Theses and Dissertations

This applied anthropology study, guided by a feminist perspective and in particular, Black Feminist Thought is an outgrowth of an evaluation study of the Partnership for Peace Program (PFP) in Grenada, West Indies. The PFP is a Caribbean-specific model that was built into a sixteen-week cycle program by the United Nations Entity for Gender Equality and Empowerment of Women (UNWomen). Since 2005, the PFP has been geared towards Grenadian men, who have used violence against women to express their masculine identities. PFP focuses exclusively on rehabilitating male perpetrators with a goal to protect the human rights of women. This research ...


Beliefs Of And Attitudes Toward Sexual Violence By A Diverse Group Of Self-Identified Male Collegiate Athletes, Belinda-Rose James Jan 2012

Beliefs Of And Attitudes Toward Sexual Violence By A Diverse Group Of Self-Identified Male Collegiate Athletes, Belinda-Rose James

Graduate Theses and Dissertations

The objective of this research was to assess the beliefs of and attitudes towards sexual violence among self-identified male, undergraduate, athletes and non-athletes. Research has shown that there is an association between the subculture of athletics and the beliefs and attitudes towards sexual violence. Male, undergraduate, athletes have disproportionately been reported for sexual violence. This study examined common risk factors attributed to perpetration of sexual violence: rape myth acceptance, lower attitudes toward women, reactive aggression, and physical and verbal sexual coercion. Multiple-level risk factors were studied in order to acquire a comprehensive understanding of what possible associations between male collegiate ...


Willingness-To-Pay For Maintenance And Improvements To Existing Sanitation Infrastructure: Assessing Community-Led Total Sanitation In Mopti, Mali, Justin Vern Meeks Jan 2012

Willingness-To-Pay For Maintenance And Improvements To Existing Sanitation Infrastructure: Assessing Community-Led Total Sanitation In Mopti, Mali, Justin Vern Meeks

Graduate Theses and Dissertations

In recent years, much focus has been put on the sustainability of water and sanitation development projects. Experts in this field have found that many of the projects of the past have failed to achieve sustainability because of a lack of demand for water and sanitation interventions at a grassroots level. For years projects looked to create this demand through various subsidy schemes, with the "software" of behavior change and education taking a backseat to the "hardware" of infrastructure provision. Community-Led Total Sanitation (CLTS) is a fairly new way of looking at the issues of increasing basic sanitation coverage, promoting ...


The Yellow Flag Of Quarantine: An Analysis Of The Historical And Prospective Impacts Of Socio-Legal Controls Over Contagion, Peter Oliver Okin Jan 2012

The Yellow Flag Of Quarantine: An Analysis Of The Historical And Prospective Impacts Of Socio-Legal Controls Over Contagion, Peter Oliver Okin

Graduate Theses and Dissertations

Under the ancient threat of morbidity and mortality from infectious diseases, human societies have responded for thousands of years by imposing social containment measures. Even before theorists and laymen recognized the existence of pathogenic organisms, or fully understood the principles of contagion, many societies and individuals did empirically infer that such diseases were transmissible from human to human (as well as sometimes between animals and humans). Having few effective technological measures to prevent or treat contagions, they did devise a variety of socio-behavioral procedures for separating overtly ill persons or suspected disease-carriers from nominally uninfected people. These methods included various ...


Love And Risk: Intimate Relationships Among Female Sex Workers Who Inject Drugs And Their Non-Commercial Partners In Tijuana, Mexico, Jennifer L. Syvertsen Jan 2012

Love And Risk: Intimate Relationships Among Female Sex Workers Who Inject Drugs And Their Non-Commercial Partners In Tijuana, Mexico, Jennifer L. Syvertsen

Graduate Theses and Dissertations

This dissertation examines the influence of love and other emotions on sexual and drug-related HIV risk among female sex workers who inject drugs and their intimate, non-commercial partners in Tijuana, Mexico. My work on a public health study along the Mexico-U.S. border and independent ethnographic research in Tijuana suggests the importance of emotions in shaping sex workers' relationships and health risks.

Love is a universal human emotional experience embodied within broader cultural, social, and economic contexts. A growing body of cross-cultural research suggests that modern relationships have transformed to emphasize love and emotional intimacy over moral or kinship obligations ...


Discovery Of A Functional Ecdysone Response Element In Brugia Malayi, Tracy Enright May 2011

Discovery Of A Functional Ecdysone Response Element In Brugia Malayi, Tracy Enright

Graduate Theses and Dissertations

The aim of this study was to determine whether functional ecdysone response elements (EcREs) exist within the genome of Brugia malayi, a parasitic nematode that causes lymphatic filariasis. The hypothesis that EcREs exist in B. malayi stemmed from previous demonstration of a functional ecdysone response system in B. malayi (Tzertzinis et al., 2010). Real-time PCR (qPCR) experiments were conducted to measure gene expression levels for twelve genes proximal to five putative EcREs in 20-OH ecdysone treated and untreated B. malayi embryos. Seven genes showed consistent upregulation with 20-OH ecdysone treatment. Each of the five putative EcREs had at least one ...


An Observation Of Immunological Effect, A Diet Enhanced With Spirulina And Treatment With Fractalkine In Models Of Parkinson's Disease, Mibel Pabón May 2011

An Observation Of Immunological Effect, A Diet Enhanced With Spirulina And Treatment With Fractalkine In Models Of Parkinson's Disease, Mibel Pabón

Graduate Theses and Dissertations

In my dissertation research we used use human wild type α-synuclein gene expression using an adeno-associated viral vector (AAV9) that induced a slowly progressive loss of dopamine (DA) neurons in the Substantia nigra (SN) as one of our animal model of Parkinson’s disease (PD). It is our hypothesis that neuroinflammation predisposes the brain to susceptibility to neurodegenerative diseases. Thus we examined the progression of a PD lesion and examined the manipulations of the immune system to understand further the inflammatory role when we administered exogenous soluble fractalkine.

The specific etiology of neurodegeneration in PD is unknown, but the inflammatory ...