Arts and Humanities Commons^™

Site-Directed Mutations In The C-Terminal Extension Of Human Αb-Crystallin Affect Chaperone Function And Block Amyloid Fibril Formation, T. M. Treweek, Heath Ecroyd, D. M. Williams, S. Meehan, J. A. Carver, M. J. Walker

Heath Ecroyd

Alzheimer’s, Parkinson’s and Creutzfeldt-Jakob disease are associated with inappropriate protein deposition and ordered amyloid fibril assembly. Molecular chaperones, including αBcrystallin, play a role in the prevention of protein deposition. A series of site-directed mutants of the human molecular chaperone, αB-crystallin, were constructed which focused on the flexible C-terminal extension of the protein. We investigated the structural role of this region as well as its role in the chaperone function of αB-crystallin under different types of protein aggregation, i.e. disordered amorphous aggregation and ordered amyloid fibril assembly. It was found that mutation of lysine and glutamic acid residues in the C-terminal …

Hallucination Proneness, Schizotypy And Meta-Cognition, John Stirling, Emma Barkus, Shon Lewis

Emma Barkus

Disordered or maladaptive meta-cognitive processing appears to be a prominent feature for some individuals with a diagnosis of schizophrenia. We sought to establish whether healthy individuals distinguished either in terms hallucination proneness (HP) or level of schizotypy could also be differentiated on the sub-scales of the Meta-cognitions Questionnaire (MCQ), or a modified version of it in which items about worry were replaced with items specifically related to thinking. A total of 106 healthy volunteers completed the Oxford and Liverpool Inventory of Feelings and Experiences and Launay-Slade hallucination scale, the Schizotypal Personality Questionnaire and two versions of the MCQ: the original …

Ecstasy (Mdma) And Its Relationship With Self Report Depression, Anxiety And Schizotypy, Lisa Woods, Emma Barkus

Emma Barkus

Abstract. Aims: The relationship between ecstasy and affective psychological symptoms are still subject to debate. We aimed to examine the relationship between Ecstasy use and self-report depression, anxiety and schizotypy. Design: Data were collected via structured remote self-report questionnaires. Participants: Participants were split into three groups: a control group with no ecstasy use, a light ecstasy user group (<50 >times), and a heavy ecstasy user group (>50 times). Measurements: Amount and patterns of ecstasy use were recorded, the Beck Depression Inventory (BDI), and Beck Anxiety Inventory (BAI) measured depression and anxiety respectively, and schizotypal traits were measured using the …

Understanding And Using Advanced Statistics, Jeremy Foster, Emma Barkus, Christian Yavorsky

Emma Barkus

The spread of sophisticated computer packages and the machinery on which to run them has meant that procedures which were previously only available to experienced researchers with access to expensive machines and research students can now be carried out in a few seconds by almost every undergraduate. Understanding and Using Advanced Statistics provides the basis for gaining an understanding of what these analytic procedures do, when they should be used, and what the results provided signify. This comprehensive textbook guides students and researchers through the transition from simple statistics to more complex procedures with accessible language and illustration.

Cannabis-Induced Psychosis-Like Experiences Are Associated With High Schizotypy, Emma Barkus, John Stirling, Richard Hopkins, Shon Lewis

Emma Barkus

OBJECTIVE: Recent studies have suggested that cannabis use is a risk factor for developing schizophrenia. We tested the hypothesis that cannabis use increases the likelihood of psychosis-like experiences in non-clinical participants who scored highly on a measure of schizotypy. METHOD: The psychological effects of cannabis were assessed in 137 healthy individuals (76% female, mean age 22 years) using a newly developed questionnaire concerned with subjective experiences of the drug: the Cannabis Experiences Questionnaire. The questionnaire has three subscales: Pleasurable Experiences, Psychosis-Like Experiences and After-Effects. Respondents also completed the brief Schizotypal Personality Questionnaire. RESULTS: Cannabis use was reported by 72% of …

Cannabis-Induced Psychotic-Like Experiences Are Predicted By High Schizotypy. Confirmation Of Preliminary Results In A Large Cohort., John Stirling, Emma Barkus, L Nabosi, S Irshad, G Roemer, B Schreudergoidheijt, Shon Lewis

Emma Barkus

Background: Cannabis use has been identified as a possible risk factor for developing schizophrenia. In a previous paper we reported preliminary evidence that cannabis use increases the likelihood of psychosis-like experiences in non-clinical respondents who scored highly on a measure of schizotypy. We now present findings from pooled data from 3 new follow-up studies comprising a sample of 477 respondents, of whom 332 reported using cannabis at least once. Sampling and Methods: As in our previous study, the psychological effects of cannabis were assessed with the Cannabis Experiences Questionnaire, from which 3 subscales can be derived; encompassing pleasurable experiences, psychosis-like …

Suggestibility, Dissociation And Positive Schizotypy, Emma Barkus, John Stirling, John Cavill

Emma Barkus

Abstract. 94 participants, drawn from a parent sample of 1206 individuals who had previously taken part in an assessment of the factor structure of the Oxford-Liverpool Inventory of Feelings and Experiences (O-LIFE), were designated into groups differentiated in terms of low, moderate or high levels of positive schizotypy. All also completed the dissociative experiences scale (DES) and the Inventory of Suggestibility (IS). Our findings suggest that higher reported levels of dissociative experiences and higher suggestibility both independently predict higher scores of positive schizotypy, although suggestibility appears to be a stronger predictor than dissociation.

Schizotypy And Psychosis-Like Experiences From Recreational Cannabis In A Non-Clinical Sample, Emma Barkus, Shon Lewis

Emma Barkus

Background. The relationship between cannabis use and psychosis is still a matter for debate. Accounting for the individual differences in subjective experiences to recreational cannabis use in the general population may hold some clues to the aetiological relationship between cannabis and psychotic symptoms. We hypothesized that schizotypy would account for the individual differences in subjective experiences after cannabis use but not in patterns of use. Method. In a sample of 532 young people who had used cannabis at least once, we examined the relationship between the Cannabis Experiences Questionnaire (CEQ) and the Schizotypal Personality Questionnaire (SPQ). Additionally, we examined the …

Distress And Metacognition In Psychosis Prone Individuals: Comparing High Schizotypes To The At-Risk Mental State, Emma Barkus, John Stirling, Paul French, Anthony Morrison, Richard Bentall, Shon Lewis

Emma Barkus

Both schizotypy and at-risk mental states (ARMS: prodromal states) define individuals at risk for psychotic symptoms. However, the relationship between the 2 is unclear. ARMS individuals are, by definition, help-seeking and therefore at greater risk. We tested whether high schizotypes and ARMS exist along the same continuum by examining maladaptive metacognitions and distress. About 95 healthy volunteers (39% male; mean age, 22.8 years) completed the Schizotypal Personality Questionnaire, the Launay-Slade Hallucinations Scale, Metacognitions Questionnaire (MCQ), and the General Health Questionnaire, and 58 help seeking individuals with ARMS status (41% male; mean age, 22.2 years) completed the Metacognitions Questionnaire and General …

Personality And Cannabis Use, Emma Barkus

Emma Barkus

Cannabis is one of the most widely used illegal substances in the world. Its use has been reported to be over-represented in many psychiatric conditions and has frequently been found to predate the onset of psychiatric symptoms. However, cannabis may also have detrimental effects on the general population. Factors that predict the onset of use are receiving increased attention to aid in identifying groups of young people who may be more prone to consume cannabis. Personality traits may be one such factor as they are readily identifiable and offer information that can be used for improved targeting of educational material …

Midwifery And The Context Of Care: Is It Possible To Be 'Woman Centred'?, Moira Williamson, Lindsey Harrison

Moira Williamson

Title: Midwifery and the context of care: Is it impossible to be ‘woman centred’? Dr Moira Williamson, School of Nursing, Midwifery and Indigenous Health, University of Wollongong, Northfields Avenue, Wollongong NSW 2522, Australia, ph. +61 2 4221 3381, email: moiraw@uow.edu.au Dr Lindsey Harrison, School of Health Sciences, University of Wollongong Background: Findings from a qualitative study show that the context of care can inhibit midwives’ provision of woman centred care; especially impacted is their ability to provide culturally appropriate care. Aim of the Study: The aims of the study were to gain an understanding of midwives’ concepts of culture and …

Workforce Issues, Skill Mix, Maternity Services And The Enrolled Nurse : A Discussion, Moira Williamson, Avon Strahle

Moira Williamson

New South Wales (NSW) is experiencing a shortage of registered midwives. Currently midwives are being actively recruited for 125 metropolitan and 45 rural positions in area health services across the state. This shortage of registered midwives is occurring not only in NSW but also throughout Australia, and has also been reported internationally (McKenna & Hasson, 2002; Keeney et al. 2005). In an attempt to address the ongoing shortage of registered nurses and midwives the NSW Health Department has proposed that a skill mix of 80% registered nurses or midwives to 20% enrolled nurses be implemented within hospitals. This initiative will …

Child Birth: Don't Forget The Fathers, Moira Williamson

Moira Williamson

Fathers are often forgotten when a new baby comes into a family. But men face many challenges in the early months of fatherhood as they come to terms with their new or expanded role. And they need more support. UOW Senior Lecturer and Master of Science (Midwifery) Co-ordinator Moira Williamson and colleagues Professor Carol McVeigh from Massey University (NZ) and Mercy Baafi, Midwifery Manager (Education) at Wollongong Hospital, researched the impact of parenthood with 128 new fathers. MOIRA WILLIAMSON prepared this Opinion column, based on their research.

Front Of Pack Daily Intake Labelling On Australian Packaged Foods: Introduction And Use 2007-2009, P Williams, R Duncan, K De Agnoli, A Hull, A Owers, T Wang

Peter Williams

This study aimed to measure the extent of use of front-of-pack daily intake (DI) labelling across food categories in Australian supermarkets, and assess the level of compliance with the Australian Food and Grocery Council (AFGC) guidelines. Surveys of six supermarkets in the Illawarra region of New South Wales were conducted twice a year in 2007, 2008 and 2009. The number of products with DI labelling increased from 58 in February 2007 to 1939 in August 2009 and appears to be growing strongly. The greatest number of products with the labelling are in the biscuits and crackers, cooking sauces, breakfast cereals, …

Breast Cancer Detection Messages In Australian Print Media Advertising - Are They Promoting Correct Information?, Sandra C. Jones, John R. Rossiter

Sandra Jones

With breast cancer now the leading cause of cancer deaths among women in the western world, correct information about detection and treatment is vitally important. The media are often accused of conveying inaccurate information in their editorial coverage of health issues, but few studies have examined the accuracy of information in media advertising. In this study of breast cancer detection ads in Australian magazines and newspapers, many instances of misleading information were found. As the print media have a major influence on women's health beliefs, these findings have serious implications for health communication policy regarding socially responsible advertising.

Disease Awareness Advertising: Women's Intentions Following Exposure, Danika Hall, Sandra C. Jones, Donald C. Iverson

Sandra Jones

Background: In Australia, where direct to consumer advertising of prescription medicines is prohibited, pharmaceutical companies can sponsor disease awareness advertising targeting consumers. This study examined the impact of disease awareness advertising exposure on older women's reported behavioural intentions. Method: Women were approached in a shopping centre and randomly assigned mock advertisements for two health conditions. Disease information and sponsors were manipulated. Results: Two hundred and forty-one women responded to 466 advertisements. Almost half reported an intention to ask their doctor for a prescription or referral as a result of seeing the advertisement, but more reported they would talk to their …

Alcohol Energy Drinks: Is It Time For The Alcohol Industry To Demonstrate Some Corporate Social Responsibility?, Sandra Jones

Sandra Jones

There is increasing evidence of association between AEDs and both increased alcohol consumption and increased alcohol-related harm. Australia lags behind other countries in researching and regulating (alcoholic and non-alcoholic) energy drinks. Twelve focus groups were conducted with 12-17 year olds in a capital city, regional city and rural city in NSW, Australia. AEDs were popular among teenagers in urban, regional and rural areas of NSW. Adolescents liked AEDs because they provide increased energy while allowing them to feel the effects of alcohol, and because of their similarity to non-alcohol energy drinks and soft drinks. Given the industry’s stated position on …

Point-Of-Sale Alcohol Promotions In The Perth And Sydney Metropolitan Areas, Sandra C. Jones, Lance R. Barrie

Sandra Jones

There is considerable evidence that reducing the price of alcohol increases the amount consumed, particularly among young people. However, there is an absence of research on other point-of-sale (POS) alcohol marketing strategies - such as those that ‘reward’ purchasers with free gifts. The purpose of the present study was to document the nature and extent of POS alcohol promotions in bottle shops in two Australian capital cities. An audit tool was developed and point-of-sale promotions were found to be ubiquitous, with 416 promotions identified across 24 audits (an average of 17.3 promotions per outlet; 19.8 in Sydney and 14.9 in …

Methodological Difficulties In A Systematic Review Of Social Marketing For Sun Protection: Implications For Research And Practice, Sandra C. Jones, Keryn Johnson

Sandra Jones

This paper reports on a systematic review of all published skin cancer primary prevention interventions aimed at improving the sun protection of children and adolescents, from 1980 to 2005. This was undertaken to inform the development of future social marketing campaigns for the prevention of skin cancer. Rather than reporting the findings of the review, in terms of conclusions drawn about the effectiveness of interventions, this paper focuses on the systematic review process itself - identifying and discussing the methodological difficulties that arose in conducting this review. These difficulties, from lack of information on the development and theoretical background of …

Evaluating The Impact Of The Dandenong Public Drinking Campaign, Lance R. Barrie, Sandra C. Jones, Dona Macik, Peter Griffith

Sandra Jones

In 2009, Dandenong launch a campaign targeting drinking in public places using stencils, posters and stickers in community settings and bottle-shops. An evaluation was undertaken and 152 participants completed a survey where elements of the Health Belief Model (HBM) were explored. Over 65% of respondents reported that they had seen at least 4 different advertisements, suggesting that the campaign dissemination was very effective. The campaign had a high recall rate and over 25% of people had either stopped or intended to stop drinking in public places. Overall, awareness of the negative effects of drinking in public increased; however no follow …

Process Evaluation Of An Innovative Sun Protection Intervention Targeting Adolescents, Sandra C. Jones, Keryn M. Johnson, Donald C. Iverson, Jeffrey Thom

Sandra Jones

The purpose of the current intervention was to target a defined segment of the adolescent population with a sun protection ‘offering’ that positioned sun protection as beneficial and addressed identified barriers (particularly inconvenience and image). A community intervention was conducted in one defined geographic region over the 2009/2010 Summer school holidays. Key elements of the intervention included the distribution of augmented products, promotional materials with a pre-tested impactful message, and partnerships with community and commercial organisations. The intervention was successful in creating interest and attention among adolescents. This paper reports on the process evaluations, focusing on barriers, facilitators and lessons …

"At Least I'M Not Drink-Driving": Formative Research For A Social Marketing Campaign To Reduce Drug-Driving Among Young Drivers, Lance R. Barrie, Sandra C. Jones, Elizabeth Wiese

Sandra Jones

This paper reports on a qualitative study designed to examine young drivers’ knowledge and attitudes regarding drug-driving, as the formative research for a potential drug-driving social marketing program in the Australian Capital Territory (ACT). Drug driving has been found to be associated with motor vehicle accidents, particularly among younger drivers. However, the potential for social marketing in this area has received little attention. This study found that young people were not aware of the effects of drugs on driving, formed their perceptions of risk (both of getting caught and of impaired driving) based on other people’s experiences, and felt that …

General Practice Registrars: Attitudes Of Older Patients, Andrew D. Bonney, Sandra C. Jones, Lyn Phillipson, Donald C. Iverson

Sandra Jones

Previous research indicates that older patients may be less willing to consult general practice registrars (GPRs), reducing training opportunities in chronic/complex care. This survey explores older patients’ attitudes in order to inform models of interaction that would be acceptable to patients. METHODS Ten training general practices distributed questionnaires for self completion to 50 patients aged 60 years and over. Chi-square, Spearman’s rho and logistic regression were used for analysis. RESULTS The response rate was 47%. Ninetysix percent wanted ongoing contact with their general practitioner if they saw a GPR. Twenty-four percent were comfortable with GPR chronic/complex care, increasing to 73% …

Case Study In Academic And Industry Collaboration: The Development Of An Adolescent Targeted Sun Protection Intervention In Nsw, Melinda Williams, Sandra Jones, Donald Iverson, Peter Caputi, Sofia Potente

Sandra Jones

Academic and industry collaboration is increasingly identified as a critical element in the future health of Australians through linking theory and practice, with the major priority for academic institutions being the identification of new knowledge and the transfer of this knowledge into changes in policy and health services. Collaborations between academia and industry are increasingly encouraged in Australia by research funding schemes such as ARCLinkage and, more recently, NHMRC Partnerships. While a recent US study suggests that such schemes have a moderate effect on academics’ propensity to work with industry (Bozeman and Gaughan, 2007), industry groups have recognised the value …

Preparing For An Ageing Population: A Survey Of Older Patients' Attitudes To General Practice Registrars, Andrew D. Bonney, Sandra C. Jones, Lyn Phillipson, Donald C. Iverson

Sandra Jones

The ageing population makes it imperative to provide appropriate training for general practice registrars (GPRs) in the community-based care of older patients. However, data suggest that older patients may be less willing to consult GPRs for chronic/complex care; adversely affecting training opportunities and potentially the satisfaction of older patients in training practices. This cross-sectional study was undertaken to investigate this concern in the Australian context and develop models of older patient-GPR interaction that are acceptable to patients.

The Effect Of Exercise On The Skeletal Muscle Phospholipidome Of Rats Fed A High-Fat Diet, Todd W. Mitchell, N. Turner, Paul Else, Anthony J. Hulbert, John Hawley, Jong Sam Lee, Clinton Bruce, Stephen J. Blanksby

Stephen Blanksby

The aim of this study was to examine the effect of endurance training on skeletal muscle phospholipid molecular species from high-fat fed rats. Twelve female Sprague- Dawley rats were fed a high-fat diet (78.1% energy). The rats were randomly divided into two groups, a sedentary control group and a trained group (125 min of treadmill running at 8 m/min, 4 days/wk for 4 weeks). Forty-eight hours after their last training bout phospholipids were extracted from the red and white vastus lateralis and analyzed by electrospray-ionization mass spectrometry. Exercise training was associated with significant alterations in the relative abundance of a …

Gauging Gender: A Metaphysics, Stephen Asma

Stephen T Asma

In this article the author discusses sex and gender in human beings and examines how the study of science, particularly biology, has influenced the study of these subjects in higher education. It traces the evolution of sex and gender studies in academe, comments on the failure of many humanities scholars to dismiss biology in studying human behavior, and explores ways in which psychoanalysis, social constructionism, and metaphysics have informed the debate over the differences between sex and gender. Other topics include research conducted by Anne Fausto-Sterling regarding intersexed people, scientific tests focusing on sexual preference in rats, and thoughts by …

An Exploratory Study Of Older Adults' Perceptions Of Dtca For Prescription Medications, Sandra C. Jones, Judy Mullan

Judy Mullan

There are many arguments for and against Direct-To-Consumer-Advertising (DTCA) and their impact on the consumer. A study involving 97 older consumers was carried out to investigate their perceptions about long or short versions of written DTCA for arthritis or diabetes medication. The results indicate that even though the ads may improve doctor-patient discussion about medications, they would not necessarily empower them to make decisions. Some of the consumers also believed that DTCA might cause people to ask for inappropriate medicines, become confused and possibly stop seeking medical advice.

Food In My Back Yard (Fimby) Implementing Urban Agriculture Into Australian Suburbs, Ned Wales, Nicole Webb

Ned Wales

The Corporate Agenda For Environmental Property Rights, Sharon Beder

Sharon Beder

Market and property-rights based approaches to environmental problems have been heavily promoted by conservative think tanks. Consequently policies such as emissions trading, water markets, tradeable fishing quotas and conservation banking pervade environmental policy in English speaking nations. They have enabled the corporate neo-liberal agenda of deregulation, privatisation and an unconstrained market to be dressed up as an environmental virtue. This market-faith based approach is proving to be largely ineffective at protecting the environment and also inequitable.