Open Access. Powered by Scholars. Published by Universities.®

Arts and Humanities Commons

Open Access. Powered by Scholars. Published by Universities.®

Philosophy

1999

Human Experimentation

Articles 1 - 6 of 6

Full-Text Articles in Arts and Humanities

What's The Price Of A Research Subject?, Charles Weijer Nov 1999

What's The Price Of A Research Subject?, Charles Weijer

Charles Weijer

No abstract provided.


Thinking Clearly About Research Risk: Implications Of The Work Of Benjamin Freedman, Charles Weijer Oct 1999

Thinking Clearly About Research Risk: Implications Of The Work Of Benjamin Freedman, Charles Weijer

Charles Weijer

No abstract provided.


Research Involving The Vulnerable Sick, Charles Weijer Sep 1999

Research Involving The Vulnerable Sick, Charles Weijer

Charles Weijer

Research involving the vulnerable sick raises difficult challenges for investigators and Institutional Review Boards. Exactly who among the ill counts as vulnerable is a matter of judgement, and involves consideration of susceptibility to harm and capacity to provide free and informed consent. A balanced approach is required when protections are considered, and the benefits as well as the risks of research participation must be carefully weighed. A variety of protections for the vulnerable sick in research are available, including enrolling subjects in a study only with a strong justification, ensuring that consent is free and comprehending, and setting limits on ...


Protecting Communities In Research: Philosophical And Pragmatic Challenges, Charles Weijer Sep 1999

Protecting Communities In Research: Philosophical And Pragmatic Challenges, Charles Weijer

Charles Weijer

The issue of the protection of communities in clinical research first arose 10 years ago in studies conducted in technologically developing countries by scientists from technologically developed nations. The question was, which ethical standards ought to apply, those of the Western investigators or local standards?


Structuring The Review Of Human Genetics Protocols Part-Iii: Gene Therapy Studies, Kathleen Glass, Charles Weijer, Denis Cournoyer, Trudo Lemmens, Roberta Palmour, Stanley Shapiro, Benjamin Freedman Feb 1999

Structuring The Review Of Human Genetics Protocols Part-Iii: Gene Therapy Studies, Kathleen Glass, Charles Weijer, Denis Cournoyer, Trudo Lemmens, Roberta Palmour, Stanley Shapiro, Benjamin Freedman

Charles Weijer

No abstract provided.


Selecting Subjects For Participation In Clinical Research: One Sphere Of Justice, Charles Weijer Jan 1999

Selecting Subjects For Participation In Clinical Research: One Sphere Of Justice, Charles Weijer

Charles Weijer

Recent guidelines from the US National Institutes of Health (NIH) mandate the inclusion of adequate numbers of women in clinical trials. Ought such standards to apply internationally? Walzer's theory of justice is brought to bear on the problem, the first use of the theory in research ethics, and it argues for broad application of the principle of adequate representation. A number of practical conclusions for research ethics committees (RECs) are outlined. Eligibility criteria in clinical trials ought to be justified by trial designers. Research ethics committees ought to question criteria that seem to exclude unnecessarily women from research participation ...