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Bioethics and Medical Ethics

Selected Works

1996

Treatment Outcome

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Full-Text Articles in Arts and Humanities

What Difference Does It Make To Be Treated In A Clinical Trial? A Pilot Study, Charles Weijer, Benjamin Freedman, Abraham Fuks, James Robbins, Stanley Shapiro, Myriam Skrutkowska May 1996

What Difference Does It Make To Be Treated In A Clinical Trial? A Pilot Study, Charles Weijer, Benjamin Freedman, Abraham Fuks, James Robbins, Stanley Shapiro, Myriam Skrutkowska

Charles Weijer

OBJECTIVE: Pilot study to characterize treatment differences between patients treated in clinical trials and those treated in a clinical setting. Previous studies have shown higher survival rates for participants in trials of cancer therapy. This difference is observed even after rates are adjusted for important covariates such as age and stage of disease.

DESIGN: Retrospective chart review.

SETTING: Oncology outpatient department in a tertiary care hospital.

PATIENTS: Ninety women 18 to 70 years of age with early-stage breast cancer who were diagnosed in 1990. Fifty-one of the women were treated through clinical trials and 39 were treated outside of clinical …