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Synthesis Of Smz Derivatives And Investigation Of Effects On Germination, Root, And Plant Growth Of \Textit{Arabidopsis Thaliana} L., Tuğba Güngör, Ferah Cömert Önder, Fati̇h Sezer, Aslihan Özbi̇len, Kemal Meli̇h Taşkin, Mehmet Ay

Turkish Journal of Chemistry

A series of sulfonamide derivatives were synthesized by reactions with various functional groups containing benzenesulfonyl chlorides and aniline derivatives under different substitution reaction conditions. The structures of SMZ derivatives were confirmed with melting point, FT-IR, $^{1}$H NMR, $^{13}$C NMR, and LC-MS/MS techniques. In order to investigate the cytotoxic effects of these derivatives, we used a model plant species. The synthesized compounds (S1-S5) and sulfamethazine (SMZ) as a positive control were applied to Arabidopsis thaliana seeds. Our results indicated that S3 and S4 induced shorter roots and lower wet weight in plants. Plants treated with S2 and S5 showed no growth …