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Health Related Quality Of Life In Sickle Cell Patients: The Pisces Project, Donna K. Mcclish, Lynne T. Penberthy, Viktor E. Bovbjerg, John D. Roberts, Imoigele P. Aisiku, James L. Levenson, Susan D. Roseff, Wally R. Smith
Health Related Quality Of Life In Sickle Cell Patients: The Pisces Project, Donna K. Mcclish, Lynne T. Penberthy, Viktor E. Bovbjerg, John D. Roberts, Imoigele P. Aisiku, James L. Levenson, Susan D. Roseff, Wally R. Smith
Biostatistics Publications
Background Sickle cell disease (SCD) is a chronic disease associated with high degrees of morbidity and increased mortality. Health-related quality of life (HRQOL) among adults with sickle cell disease has not been widely reported.
Methods We administered the Medical Outcomes Study 36-item Short-Form to 308 patients in the Pain in Sickle Cell Epidemiology Study (PiSCES) to assess HRQOL. Scales included physical function, physical and emotional role function, bodily pain, vitality, social function, mental health, and general health. We compared scores with national norms using t-tests, and with three chronic disease cohorts: asthma, cystic fibrosis and hemodialysis patients using analysis of …