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An Str Forensic Typing System For Genetic Individualization Of Domestic Cat (Felis Catus) Samples, Marilyn A. Menotti-Raymond, Victor A. David, Leslie L. Wachter, John M. Butler, Stephen J. O'Brien
An Str Forensic Typing System For Genetic Individualization Of Domestic Cat (Felis Catus) Samples, Marilyn A. Menotti-Raymond, Victor A. David, Leslie L. Wachter, John M. Butler, Stephen J. O'Brien
Biology Faculty Articles
A forensic genotyping panel of 11 tetranucleotide STR loci from the domestic cat was characterized and evaluated for genetic individualization of cat tissues. We first examined 49 candidate STR loci and their frequency assessment in domestic cat populations. The STR loci (3-4 base pair repeat motifs), mapped in the cat genome relative to 579 coding loci and 255 STR loci, are well distributed across the 18 feline autosomes. All loci exhibit Mendelian inheritance in a multi-generation pedigree. Eleven loci that were unlinked and were highly heterozygous in cat breeds were selected for a forensic panel. Heterozygosity values obtained for the …