Digital Commons Network^™

Epigenetic Instability At Imprinting Control Regions In A KrasG12d-Induced T-Cell Neoplasm, Corey L. Bretz, Ingeborg M. Langohr, Suman Lee, Joomyeong Kim

Faculty Publications

© 2015 Taylor & Francis Group, LLC. Although aberrant DNA methylation within imprinted domains has been reported in a variety of neoplastic diseases, it remains largely uncharacterized in the context of carcinogenesis. In this study, we induced T-cell lymphoma in mice by employing a breeding scheme involving mouse strains, LSL-KrasG12D and MMTV-Cre. We then systematically surveyed imprinted domains for DNA methylation changes during tumor progression using combined bisulfite restriction analysis and NGS-based bisulfite sequencing. We detected hyper- or hypo-methylation at the imprinting control regions (ICRs) of the Dlk1, Peg10, Peg3, Grb10, and Gnas domains. These DNA methylation changes at ICRs …

Examining Louisiana State University College Of Agriculture Students’ Perceived Motivators And Barriers To Participation In International Experiences, J. C. Bunch, J. Joey Blackburn, Shelli Dan Jean, Kristin E. Stair, Leslie D. Blanchard

Faculty Publications

© 2015, Assoc. Int. Agricultural and Extension Education. All rights reserved. In an effort to internationalize higher education and produce globally competent professionals, many universities have increased the time and financial assets put toward promoting an international experience (IE). Research supports using an IE to supplement international education efforts and help students develop the global perspective and experience needed to succeed in the workplace. The purpose of this study was to determine College of Agriculture (CoA) students’ perceptions of IE participation, and identify factors that CoA students perceived as barriers and motivators to participation in an IE. CoA students were …

Faculty Senate Newsletter, Holiday 2015, Louisiana State University And Agricultural & Mechanical College

LSU Faculty Senate Publications

Message from President: At the end of the LSU-Texas A&M game, television captured Les Miles standing in the embrace of a burly player, insistently singing the LSU alma mater. Any comedy that might have inhered in such an effort at roughhouse opera deteriorated under the impression that the performance was sending a bullying message to LSU officials about the alleged high level of public support for a coach rumored to be fighting for his job. By exploiting a musical component from the sacraments of the academic community for exclusively personal ends, the beleaguered coach helped everyone to understand what has …

Political Identity Of Louisiana’S College Voters An Analysis Of Their Opinions, Habits, And Politics, Milton Joseph Hernandez Iv

Honors Theses

No abstract provided.

Cellular And Molecular Remodeling Of Inguinal Adipose Tissue Mitochondria By Dietary Methionine Restriction, Yuvraj N. Patil, Kelly N. Dille, David H. Burk, Cory C. Cortez, Thomas W. Gettys

Faculty Publications

© 2015 Elsevier Inc. Dietary methionine restriction (MR) produces a coordinated series of biochemical and physiological responses that improve biomarkers of metabolic health, increase energy expenditure, limit fat accretion and improve overall insulin sensitivity. Inguinal white adipose tissue (IWAT) is a primary target and site of action where the diet initiates transcriptional programs linked to enhancing both synthesis and oxidation of lipid. Using a combination of ex vivo approaches to assess dietary effects on cell morphology and function, we report that dietary MR produced a fourfold increase in multilocular, UCP1-expressing cells within this depot in conjunction with significant increases in …

Fetal Programming In Meat Production, Min Du, Bo Wang, Xing Fu, Qiyuan Yang, Mei Jun Zhu

Faculty Publications

© 2015 Elsevier Ltd. Nutrient fluctuations during the fetal stage affects fetal development, which has long-term impacts on the production efficiency and quality of meat. During the early development, a pool of mesenchymal progenitor cells proliferate and then diverge into either myogenic or adipogenic/fibrogenic lineages. Myogenic progenitor cells further develop into muscle fibers and satellite cells, while adipogenic/fibrogenic lineage cells develop into adipocytes, fibroblasts and resident fibro-adipogenic progenitor cells. Enhancing the proliferation and myogenic commitment of progenitor cells during fetal development enhances muscle growth and lean production in offspring. On the other hand, promoting the adipogenic differentiation of adipogenic/fibrogenic progenitor …

Gubernatorial Party Affiliation And Crime, Chase Lindsey

Honors Theses

No abstract provided.

Mobilizing The Masses: How To Save Your Local Coffee Shop, Dominique Becnel

Honors Theses

No abstract provided.

Lsu Research Fall 2015, Louisiana State University And Agricultural & Mechanical College

Research Magazine

LSU Research is published annually by the Office of Research & Economic Development, Louisiana State University.

F15rs Sgr No. 15 (Gender Neutral Restrooms), Jacob Phagan

Student Senate Enrolled Legislation

No abstract provided.

"It Didn't Seem Like Race Mattered": Exploring The Implications Of Service-Learning Pedagogy For Reproducing Or Challenging Color-Blind Racism, Sarah Anna Becker, Crystal Paul

Faculty Publications

Prior research measuring service-learning program successes reveals the approach can positively affect students' attitudes toward community service, can increase students' motivation to learn and ability to internalize class material, and can change their view of social issues. Studies also suggest that college students sometimes enter and leave a field site in ways that contribute to the reproduction of inequality. In this paper, we draw on three years of data from a service-learning project that involves sending college-age students (most of whom are white and materially privileged) into local, predominantly black, high-poverty neighborhoods to participate in …

Faculty Senate Resolution 15-12, Louisiana State University And Agricultural & Mechanical College

LSU Faculty Senate Publications

Faculty Senate Resolution to oppose House Bill 707, the Louisiana Marriage and Conscience Act, adopted on May 6, 2015.

Expansion Of Brucellosis Detection In The Country Of Georgia By Screening Household Members Of Cases And Neighboring Community Members, Lia Sanodze, Christian T. Bautista, Natalia Garuchava, Svetlana Chubinidze, Ekaterine Tsertsvadze, Mariam Broladze, Nazibrola Chitadze, Ketevan Sidamonidze, Shota Tsanava, Tamar Akhvlediani, Robert G. Rivard, Rupal Mody, Matthew J. Hepburn, Philip H. Elzer, Mikeljon P. Nikolich, Nino Trapaidze

Faculty Publications

© 2015 Sanodze et al.; licensee BioMed Central. Background: Brucellosis is considered as endemic zoonotic disease in the country of Georgia. However, the burden of the disease on a household level is not known. Therefore, this study sought to determine the benefits of active surveillance coupled to serological screening for the early detection of brucellosis among close contacts of brucellosis cases. Methods: We used an active surveillance approach to estimate the rate of seropositivity among household family members and neighboring community members of brucellosis index cases. All participants were screened using the serum tube agglutination test (SAT). Blood cultures were …

The Dynamics Of Memory Retrieval: Using Mouse Movements To Test Single­ And Dual­Process Theories, Brittany Martin

Honors Theses

No abstract provided.

Surviving The Velvet Hammer: Analyzing The Criminalization Of Working Class Mothers In A Neoliberal Context, Grace Reinke

Honors Theses

No abstract provided.

Grammatical Morphology In A Child With Autism, Katherine Ball

Honors Theses

No abstract provided.

Proficiency In Native And Nonnative English Speakers: The Effects Of Individual Difference Variables On Performance, Haley E. Barlow

Honors Theses

No abstract provided.

Employing Extracellular Vesicles To Overcome Immunological Barriers To Aav- Mediated Gene Transfer & Ethical And Policy Implications Of Orphan Drug Development And Accessibility, Zachary Fitzpatrick

Honors Theses

No abstract provided.

Synthesis, Functionalization, And Characterization Of Metallic And Organic Nanoparticles For Biomedical Applications, Christopher Brian Sylvester

Honors Theses

No abstract provided.

Faculty Senate Newsletter, May 2015, Louisiana State University And Agricultural & Mechanical College

LSU Faculty Senate Publications

Message from President: Readers of heroic literature such as that written by Homer, Virgil, and an assortment of epic poets know that various forms of shame—embarrassment; bashfulness; reticence; and shyness to name but a few—serve as powerful mechanisms of social control. None of the warriors in Beowulf want their peers to regard them as less than valorous, hence will do anything, including courting of self-destruction, to avoid reprobation. Our ivy-covered walls stand far away from the shores of Troy, yet shame and shaming remain effective tools for controlling even freethinking academic people. In its various disguises, shame may well count …

The Law Of Peoples And Cosmopolitan Idealism: Global Justice For The Modern World, Jonathan Aker

Honors Theses

No abstract provided.

Retrotransposon-Derived Promoter Of Mammalian Aebp2, Hana Kim, Arundhati Bakshi, Joomyeong Kim

Faculty Publications

© 2015 Kim et al. Variable DNA methylation in promoter regions has been implicated in altering transcriptional regulation. The current study analyzed the evolutionary origin and DNA methylation pattern of one of the promoters of Aebp2 . According to the results, the first promoter of Aebp2 has been derived from retrotransposons independently in the primate and rodent lineages. DNA methylation analyses revealed that this promoter is unmethylated in sperm, methylated in mature oocytes, and partially methylated at embryonic day 10.5 (78.3%) and 14.5 (58.3%). This promoter also shows variable levels of DNA methylation among adult organs, ranging from the highest …

Does Cognitive Stress Result Into The Contextual Interference Effect?, Andrea Taylor Moss

Honors Theses

No abstract provided.

S15rs Sgr No. 10 (Unisex Bathrooms), Madden

Student Senate Enrolled Legislation

A RESOLUTION

To urge and request LSU to change signage on single stall bathrooms to "unisex" and to encourage the university to incorporate unisex bathrooms into renovations and new buildings.

Global Disconnect: Drug Trafficking And The Failure Of International Enforcement, Melissa Wheeler

Honors Theses

No abstract provided.

Yy1 Gene Dosage Effect And Bi-Allelic Expression Of Peg3, Bambarendage P.U. Perera, Ryoichi Teruyama, Joomyeong Kim

Faculty Publications

© 2015 Perera et al. In the current study, we tested the in vivo effects of Yy1 gene dosage on the Peg3 imprinted domain with various breeding schemes utilizing two sets of mutant alleles. The results indicated that a half dosage of Yy1 coincides with the up-regulation of Peg3 and Zim1, suggesting a repressor role of Yy1 in this imprinted domain. This repressor role of Yy1 is consistent with the observations derived from previous in vitro studies. The current study also provided an unexpected observation that the maternal allele of Peg3 is also normally expressed, and thus the expression of …

Faculty Senate Resolution 15-04, Louisiana State University And Agricultural & Mechanical College

LSU Faculty Senate Publications

Faculty Senate Resolution on addressing institutional racism in law enforcement; postponed, not adopted.

Examining The Motivations And Barriers Influencing The Decisions Of Louisiana State University College Of Agriculture Freshmen To Participate In International Experiences, Shelli Danjean, J. C. Bunch, Joey Blackburn

Faculty Publications

© 2015, Assoc. Int. Agricultural and Extension Education. All rights reserved. Over the past decade, universities in the United States (U.S) have increased time and financial investments put toward internationalizing their curricula, particularly in efforts to increase students’ participation in international experiences (IEs). Despite efforts, only 10% of U.S students participated in an IE in the 2011/2012 academic year, of which only 1.3% included students in agriculturally-related majors. The purpose of the study was to examine the motivations and barriers influencing the decisions of College of Agriculture (CoA) freshmen to participate in an international experience (IE). The majority of freshmen …

Sacred Vs. Secular Mindfulness Meditation: The Influence Of Presentation Priming On Therapeutic Effectiveness, Amanda R. Morice

Honors Theses

No abstract provided.

Front Matter

1650-1850: Ideas, Aesthetics, and Inquiries in the Early Modern Era

No abstract provided.