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High Frequency Oscillations Are Phase-Amplitude Coupled In Stress Induced Seizures Following Traumatic Brain Injury, Paul Jung Oct 2019

High Frequency Oscillations Are Phase-Amplitude Coupled In Stress Induced Seizures Following Traumatic Brain Injury, Paul Jung

Electronic Thesis and Dissertation Repository

Traumatic Brain Injury (TBI) often leads to the development of epilepsy, especially with the occurrence of stressful events. Stressors increase the levels of corticotropin-releasing factor (CRF) in the amygdala, which can be damaged by the secondary effects of TBI. It is hypothesized that the activity of CRF receptor type 1 (CRFR1) in the amygdala is altered post-TBI and supports the generation of epileptiform waves, namely high-frequency oscillations (HFOs). Sprague-Dawley rats were given a moderate TBI and in vivo recordings of the amygdala were taken during the administration of an acute tail pinch stressor. The stressor increased broadband activity …


Mental Health Stigma In College Students By Academic Major, Kristen Miller Apr 2019

Mental Health Stigma In College Students By Academic Major, Kristen Miller

Mahurin Honors College Capstone Experience/Thesis Projects

Stigma is best defined as the disapproval and shame felt by people who display characteristics not widely accepted in society. Although mental illness has become more prevalent in society through advocacy and awareness campaigns, it fails to be accepted and often individuals may feel shame that prevents them from seeking help (Dyrbye, Eacker, Durning, Brazeau, Moutier, Massie, S., et al, 2015; Givens & Tjia, 2002). Physicians in particular have been shown to have decreased help-seeking behaviors for psychological issues due to fear of professional repercussions (Dyrbye et al., 2015). Physicians also show increased levels of stress, anxiety, depression, and elevated …


A Phenomenological Study Of Graduated Nursing Student Athletes' Experiences Balancing Academics And Athletics, Robert E. Steed Apr 2019

A Phenomenological Study Of Graduated Nursing Student Athletes' Experiences Balancing Academics And Athletics, Robert E. Steed

Doctoral Dissertations and Projects

The purpose of this transcendental phenomenological study is to describe the lived experiences of eleven graduated nursing student athletes who completed traditional, four-year nursing programs while concurrently finishing four years of athletic eligibility in their respective sport at three private, Christian, Midwest universities and across three different competitive collegiate athletic divisions. The theories guiding this study are Tinto’s Theory of Individual Departure from Institutions of Higher Learning, Astin’s Theory of Student Involvement, and Lazarus and Folkman’s Transactional Model of Stress Response, as they relate to student athletes’ persistence to graduation and to nursing students who reportedly experience higher levels of …


Crf Mediates Stress-Induced Pathophysiological High-Frequency Oscillations In Traumatic Brain Injury, Chakravarthi Narla, Paul S. Jung, Francisco Bautista Cruz, Michelle Everest, Julio Martinez-Trujillo, Michael O. Poulter Mar 2019

Crf Mediates Stress-Induced Pathophysiological High-Frequency Oscillations In Traumatic Brain Injury, Chakravarthi Narla, Paul S. Jung, Francisco Bautista Cruz, Michelle Everest, Julio Martinez-Trujillo, Michael O. Poulter

Physiology and Pharmacology Publications

Copyright © 2019 Narla et al. It is not known why there is increased risk to have seizures with increased anxiety and stress after traumatic brain injury (TBI). Stressors cause the release of corticotropin-releasing factor (CRF) both from the hypothalamic pituitary adrenal (HPA) axis and from CNS neurons located in the central amygdala and GABAergic interneurons. We have previously shown that CRF signaling is plastic, becoming excitatory instead of inhibitory after the kindling model of epilepsy. Here, using Sprague Dawley rats we have found that CRF signaling increased excitability after TBI. Following TBI, CRF type 1 receptor (CRFR1)-mediated activity caused …


Mental Health Disorders In Dpt Students: Identifying Needs, Support Systems, & Challenges, Jennifer M. Bogardus Jan 2019

Mental Health Disorders In Dpt Students: Identifying Needs, Support Systems, & Challenges, Jennifer M. Bogardus

Department of Physical Therapy Student Theses, Dissertations and Capstones

Background: There is an increase in the incidence and severity of mental health disorders in university students. Doctor of Physical Therapy students are at increased risk due to physiological, environmental, and generational factors. Design: Mixed-Methods, multi-site, descriptive study Participants: Current DPT students (N= 1228 ) completed a survey and DASS-42; 20 students demonstrating moderate severity on the DASS participated in telephone interviews. Methods: Surveys were emailed to 238 DPT program directors with a request to forward to students. Following the survey, a total of 20 interviews were completed. Results: DPT students were found to have higher DASS scores than their …


Saudi Arabian Students In Postgraduate Dental Programs: Investigating Factors Associated With Burnout, Asiri Amal Jan 2019

Saudi Arabian Students In Postgraduate Dental Programs: Investigating Factors Associated With Burnout, Asiri Amal

University of the Pacific Theses and Dissertations

Burnout related to emotional and physical study or work demands affects an individual’s performance and well being. This study focused on Saudi Arabian dental residents studying in the United States and the United Kingdom who are faced with many challenges in pursuit of a higher education degree. A survey including demographic and MBI questions was distributed to assess this population’s level of burnout. The Maslach Burnout inventory (MBI) was has been widely used in the literature to assess three components of burnout: emotional exhaustion (EE), depersonalization (DEP), and (diminished) personal accomplishment (PA). Potential predictors of burnout level, tested for statistical …


Applications Of The Reflective Practice Questionnaire In Medical Education, Shane L. Rogers, Lynn E. Priddis, Nicole Michels, Michael Tieman, Lon J. Van Winkle Jan 2019

Applications Of The Reflective Practice Questionnaire In Medical Education, Shane L. Rogers, Lynn E. Priddis, Nicole Michels, Michael Tieman, Lon J. Van Winkle

Research outputs 2014 to 2021

Background: We sought to determine whether the Reflective Practice Questionnaire (RPQ) is a reliable measure of reflective capacity and related characteristics in medical students. We also planned to learn how the RPQ could be used in medical education. Methods: The RPQ is a 40 item self-report questionnaire that includes a multi-faceted approach to measuring reflective capacity. It also includes sub-scales on several other theoretically relevant constructs such as desire for improvement, confidence, stress, and job satisfaction. The reliabilities of reflective capacity and other sub-scales were determined by calculating their Cronbach alpha reliability values. In the present study, the RPQ was …