Open Access. Powered by Scholars. Published by Universities.®
Articles 1 - 1 of 1
Full-Text Articles in Entire DC Network
Gene Expression Of Selected Apoptotic Markers In Human Oral Squamous Carcinoma Hsc-3 Cell Line Treated With Myrmecodia Pendans Plant Extract, Widya Lestari, Wan N A W Yusry, Siti H. Iskandar, Solachuddin J A Ichwan, Nining I. Irfan, Wastuti H. Suriyah
Gene Expression Of Selected Apoptotic Markers In Human Oral Squamous Carcinoma Hsc-3 Cell Line Treated With Myrmecodia Pendans Plant Extract, Widya Lestari, Wan N A W Yusry, Siti H. Iskandar, Solachuddin J A Ichwan, Nining I. Irfan, Wastuti H. Suriyah
Makara Journal of Health Research
Background: Myrmecodia pendans (M. pendans), or Sarang Semut, is an epiphyte with anticancer potential. It was recently reported that it induces apoptotic activity in the human oral squamous carcinoma (HSC-3) cell line. This study aimed to investigate the effect of M. pendans treated samples on the expression of apoptotic markers, Bax and Bcl-2. Methods: M. pendans was purchased from West Papua, Indonesia. The hypocotyl was dried thoroughly and then extracted aqueously. The apoptotic activity was detected via flow cytometry. Bax and Bcl-2 expression was analyzed by quantitative real-time polymerase chain reaction. Results: Results of our cell cycle analysis reveal that …