Digital Commons Network^™

Acetate Causes Alcohol Hangover Headache In Rats, Christina R. Maxwell, Rebecca Jay Spangenberg, Jan B. Hoek, Stephen D. Silberstein, Michael L. Oshinsky

Department of Neurology Faculty Papers

Background

The mechanism of veisalgia cephalgia or hangover headache is unknown. Despite a lack of mechanistic studies, there are a number of theories positing congeners, dehydration, or the ethanol metabolite acetaldehyde as causes of hangover headache.

Methods

We used a chronic headache model to examine how pure ethanol produces increased sensitivity for nociceptive behaviors in normally hydrated rats.

Results

Ethanol initially decreased sensitivity to mechanical stimuli on the face (analgesia), followed 4 to 6 hours later by inflammatory pain. Inhibiting alcohol dehydrogenase extended the analgesia whereas inhibiting aldehyde dehydrogenase decreased analgesia. Neither treatment had nociceptive effects. Direct administration of acetate …

Epidemiological Study Of Contributing Factors In The Development Of Peptic Ulcer And Gastric Cancer Initiated By Helicobacter Pylori Infection In India, Rahul Suresh Mhaskar

USF Tampa Graduate Theses and Dissertations

Background: Helicobacter pylori (H. pylori) infection is a significant risk factor for peptic ulcer (PU) and gastric cancer (GC). Apart from the virulent CagA genotype of H. pylori environmental and dietary factors influence disease outcomes. There have been no studies addressing these factors in Western India. Hence, we conducted a case control study enrolling PU, GC patients and controls at Pune, India.

Methods: Risk factors for PU and H. pylori infection were assessed in participant interview. H. pylori status was assessed from stool by monoclonal antigen detection. To understand treatment effect, we followed 100 H. pylori positive patients.

Results: We …

Today - December 17, 2010, Loma Linda University

TODAY

Inside this issue:

-- Camp Good Grief offers bereaved kids and teens a chance to heal
-- Study takes ischemic pre-conditioning to new heights
-- Nutrition students granted Nestlé Foundation research funds
-- The study of forensic bite marks
-- Public health alumna appointed to air pollution agency
-- Faculty from allied health and medicine honored as Harvard Macy Scholars
-- Medicine professor discusses AIDS with community group
-- 'Conversations with authors' continues with December program
-- School of Public Health partners with United Way
-- Loma Linda University opens Center for Dentistry and Orthodontics
-- Physical therapy students begin …

Health Claims For Food Made In Australian Magazine Advertisements, P. G. Williams, Linda C. Tapsell, Sandra C. Jones, K. Mcconville

Sandra Jones

Aim: The aim was to describe the level of health claims being used in magazine advertisements, the categories of foods carrying health claims and the types of benefits being claimed for particular foods or food ingredients. Data were compared to similar studies of food labels and internet sites to reflect the impact of rule governance of the different media and highlight implications for the current proposed changes in food standards legislation. Methods: From January to June 2005 a survey of all print advertisements for food in Australia’s 30 top-selling magazines was undertaken. The results were compared with those from a …

A Proposal For Enhancing And Measuring Infant-Directed Maternal Utterances And Incidental Teaching Within The Safecare® Parent-Infant Interaction Module, Megan O. Smith

Public Health Theses

Child maltreatment is a serious and pervasive public health problem in the United States. In 2008, there were 772,000 children who were substantiated victims of maltreatment and 1,740 children died as a result of maltreatment. Approximately 33 percent of maltreatment victims were under the age of four. Among numerous other negative sequelae, children who have been maltreated have an elevated incidence of language delay and poor cognitive functioning, both strong predictors of literacy skills and later academic achievement. Further, maternal language input is critical to a child’s cognitive development and language acquisition. Maltreating mothers provide their children with far less …

Ada News - 12/13/2010, American Dental Association, Publishing Division

ADA News

Established in 1970 as the official newspaper of the American Dental Association, the ADA News serves practicing dentists and others allied to the dental profession in the U.S. and internationally. It is the No. 1 source of news and information about the many benefits and services the ADA delivers to members daily as well as timely information on scientific, social, political and economic developments affecting dentistry and health care.

The Ingredients Of Change: A Political Ecology Approach To Diabetes In The Somali Community Of Minnesota, Mina Tehrani

Geography Capstone Projects

In the early 1990’s, due to political circumstances at home, Somali immigrants and refugees began arriving in the state of Minnesota in large numbers. Over the past two decades, Somali immigrants have come to comprise one of the most populous ethnic groups in the Twin Cities, and are the largest Somali population in the world outside of Eastern Africa. Although quantitative data is unavailable, qualitative evidence and testimonies of healthcare professionals support the conclusion that Somali immigrants in Minnesota suffer from higher rates of diabetes than non-immigrant groups and than they likely did before migration. Why might this be the …

A Spatial And Health Burden Analysis Of Census Tract 85: Implications For Prevention And Intervention, Allison C. Edwards

Public Health Theses

New regulations requiring not-for-profit hospitals to provide documented evidence of charitable care and community benefits provide a unique opportunity for strategic and targeted investment within the given community of the hospital. And with a growing number of uninsured and underserved in the US, the need for tactical community benefits is increasing exponentially. The purpose of this capstone is to pool together the relevant resources and data necessary to guide and inform the decision making process involved in creating prevention and intervention programs tailored specifically to census tract 85. Utilizing several different forms of demographic and health data including Census, Online …

Contact Point, Arthur A. Dugoni School Of Dentistry

Contact Point

No abstract provided.

Levo-Tetrahydropalmatine Attenuates Cocaine Self-Administration Under A Progressive-Ratio Schedule And Cocaine Discrimination In Rats, John R. Mantsch, Samantha Wisniewski, Oliver Vranjkovic, Corey Peters, Amanda Becker, Abbey Valentine, Shi-Jiang Li, David A. Baker, Zheng Yang

Biomedical Sciences Faculty Research and Publications

Levo-tetrahydropalmatine (l-THP) is an alkaloid found in many traditional Chinese herbal preparations and has a unique pharmacological profile that includes dopamine receptor antagonism. Previously we demonstrated that l-THP attenuates fixed-ratio (FR) cocaine self-administration (SA) and cocaine-induced reinstatement in rats at doses that do not alter food-reinforced responding. This study examined the effects of l-THP on cocaine and food SA under progressive-ratio (PR) schedules of reinforcement and the discriminative stimulus effects of cocaine. In adult male Sprague–Dawley rats self-administering cocaine (0.5 or 1.0 mg/kg/inf), l-THP significantly reduced breaking points at the 1.875, 3.75 and 7.5 mg/kg …

Coronary Heart Disease Knowledge And Risk Factors Among Filipino-Americans Connected To Primary Care Services, Alona N. Dalusung-Angosta

Nursing Faculty Publications

Coronary heart disease (CHD) is the leading cause of death of Filipino-Americans (FAs). Despite the growing numbers of FAs in the United States, little is known about their CHD knowledge and risk factors.

The purposes of this study were to examine the baseline knowledge and risk factors of CHD among FAs and to describe the relationships between knowledge, sociodemographic, and socioeconomic characteristic variables of FAs between the ages of 35-75 years.

The study sample consisted of 120 FAs (N = 120) who were connected to primary care services. Data were collected from three primary care clinics in Las Vegas, …

Energy Webs And Nursing Praxis: Patterning In The Lived Experience Of Type 2 Diabetes, Karen Marcus Glasenapp

Doctor of Nursing Practice Projects

Diabetes is an illness best described as costly, complex, chronic, and epidemic in the United States, affecting nearly 24 million children and adults; 90% of who have type 2 diabetes (Centers for Disease Control and Prevention, 2008). On average, every 20 seconds in the United States, an individual 20 years of age and older receives a diagnosis of diabetes; yet, an estimated 6 million people with the disease remain undiagnosed (American Diabetes Association, 2010b). The financial burden of this disease, the inconsistent effectiveness of well-intentioned diabetes programs to educate and actualize change behavior, and the limited resources of millions of …

Summary Report Of The Mainecare Listening Sessions, Anush Yousefian Hansen Ms,Ma, Katherine Rosingana, Nadine Edris Msw

Disability & Aging

In September of 2010, the Muskie School of Public Service conducted four Listening Sessions with MaineCare members to gather in-depth information about their experiences on MaineCare, their likes and dislikes, and suggestions, needs and wants for improving the program. The overall goal of these sessions was to provide rich information to help inform DHHS in their design of a new managed care initiative. Funding for this project was provided by the Maine Health Access Foundation (MeHAF).

Impact Of Stress Management On Learning In A Classroom Setting, Pankaj Mandale

Masters Theses & Specialist Projects

Stress is an important feature of the lives of college students and can impact negatively on learning. The effectiveness of an in-class stress management intervention for improving course content retention was tested with a cross-over design in two introductory graduate biostatistics classes. Each class met one day per week for the duration of the semester, and was taught by the same instructor, following the same syllabus. A pretest duplicating items on the midterm and final exam was administered to all students at the first class meeting. Identical midterm and final exams were administered in both classes. During the first half …

Body Image Education As A Preventive Measure For Eating Disorders And Obesity In Ninth-Grade Students, Diana K. Keith

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Obesity and eating disorders are major public health problems in the U.S. Prevention of these problems in childhood and adolescence is crucial to avoid medical complications and costs associated with these conditions. A growing body of research supports designing and implementing interventions to prevent obesity and eating disorders simultaneously by targeting common risk factors such as poor body image. This study explored the use of a body image education unit as a preventive measure for obesity and eating disorders. Ninth-grade students attending health class in a public school in Northern Utah (n = 117) were assigned to either an intervention …

Parental Attitudes And Perceptions Related To Their Children's Physical Activity And Eating Patterns, Megan Leatham Dubois

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Children's physical inactivity and poor eating patterns have received a great deal of attention in our country and worldwide. Studies have been conducted to identify determinates related to children's physical activity and eating patterns and to identify strategies for promoting positive behaviors. Parental support is a well-accepted determinate of children's physical activity and eating patterns. However, little qualitative research has been done to determine parental attitudes and perceptions related to this critical role.

First, the study sought to gain a greater understanding of parental perspectives on their children's physical activity and eating patterns. Second, the study examined parental attitudes and …

Acetate Causes Alcohol Hangover Headache In Rats., Christina R Maxwell, Rebecca Jay Spangenberg, Jan B Hoek, Stephen D Silberstein, Michael L Oshinsky

Department of Neurology Faculty Papers

BACKGROUND: The mechanism of veisalgia cephalgia or hangover headache is unknown. Despite a lack of mechanistic studies, there are a number of theories positing congeners, dehydration, or the ethanol metabolite acetaldehyde as causes of hangover headache.

METHODS: We used a chronic headache model to examine how pure ethanol produces increased sensitivity for nociceptive behaviors in normally hydrated rats.

RESULTS: Ethanol initially decreased sensitivity to mechanical stimuli on the face (analgesia), followed 4 to 6 hours later by inflammatory pain. Inhibiting alcohol dehydrogenase extended the analgesia whereas inhibiting aldehyde dehydrogenase decreased analgesia. Neither treatment had nociceptive effects. Direct administration of acetate …

Evaluation Of Health Workforce Competence In Maternal And Neonatal Issues In Public Health Sector Of Pakistan: An Assessment Of Their Training Needs, Shabina Ariff, Sajid B. Soofi, Kamran Sadiq, Asher B. Feroze, Shuaib Khan, Sadiqua N. Jafarey, Nabeela Ali, Zulfiqar A. Bhutta

Department of Paediatrics and Child Health

Background: More than 450 newborns die every hour worldwide, before they reach the age of four weeks (neonatal period) and over 500,000 women die from complications related to childbirth. The major direct causes of neonatal death are infections (36%), Prematurity (28%) and Asphyxia (23%). Pakistan has one of the highest perinatal and neonatal mortality rates in the region and contributes significantly to global neonatal mortality. The high mortality rates are partially attributable to scarcity of trained skilled birth attendants and paucity of resources. Empowerment of health care providers with adequate knowledge and skills can serve as instrument of change. Methods: …

Structural And Antigenic Variance Between Novel Influenza A/H1n1/2009 And Influenza A/H1n1/2008 Viruses, Shailendra K. Saxena, Niraj Mishra, Rakhi Saxena, M.L. Arvinda Swamy, Pranshu Sahgal, Shailja Saxena, Shrish Tiwari, Asha Mathur, Madhavan Nair

HWCOM Faculty Publications

BACKGROUND:

The emergence of influenza A/H1N1/2009 is alarming. The severity of previous epidemics suggests that the susceptibility of the human population to H1N1 is directly proportional to the degree of changes in hemagglutinin/HA and neuraminidase/NA; therefore, H1N1/2009 and H1N1/2008 were analyzed for their sequence as well as structural divergence.

METHODOLOGY:

The structural and sequence divergence of H1N1/2009 and H1N1/2008 strains were analyzed by aligning HA and NA amino acid sequences by using ClustalW and ESyPred3D software. To determine the variations in sites of viral attachment to host cells, a comparison between amino acid sequences of HA and NA glycosylation sites …

Medical School Watercooler Newsletter - November 21, 2010, Lindsey Lyle

Watercooler Newsletter

This is the November 21, 2010 edition of the Frederick P. Whiddon College of Medicine's newsletter - Watercooler.

Contents Include:

• USA Orthopaedic Department Receives Gift from HJW Foundation
• Mark your calendars
• Holiday Toy Drive - Donate Today
• Reminder for USA Health & Dental Plan Members

Self-Protecting Bactericidal Titanium Alloy Surface Formed By Covalent Bonding Of Daptomycin Bisphosphonates., Chang-Po Chen, Eric Wickstrom

Department of Biochemistry and Molecular Biology Faculty Papers

Infections are a devastating complication of titanium alloy orthopedic implants. Current therapy includes antibiotic-impregnated bone cement and antibiotic-containing coatings. We hypothesized that daptomycin, a Gram-positive peptide antibiotic, could prevent bacterial colonization on titanium alloy surfaces if covalently bonded via a flexible, hydrophilic spacer. We designed and synthesized a series of daptomycin conjugates for bonding to the surface of 1.0 cm² Ti6Al4V foils through bisphosphonate groups, reaching a maximum yield of 180 pmol/cm². Daptomycin-bonded foils killed 53 ± 5% of a high challenge dose of 3 × 10⁵ cfu Staphylococcus aureus ATCC 29213.

Ada News - 11/15/2010, American Dental Association, Publishing Division

ADA News

Established in 1970 as the official newspaper of the American Dental Association, the ADA News serves practicing dentists and others allied to the dental profession in the U.S. and internationally. It is the No. 1 source of news and information about the many benefits and services the ADA delivers to members daily as well as timely information on scientific, social, political and economic developments affecting dentistry and health care.

Supernumerary, Ectopic Tooth In The Maxillary Antrum Presenting With Recurrent Haemoptysis., Taimur Saleem, Umair Khalid, Anam Hameed, Shehzad Ghaffar

Section of Otolaryngology, Head & Neck Surgery

Ectopic eruption of teeth in non-dental sites is a rare phenomenon and can present in a variety of ways such as chronic or recurrent sinusitis, sepsis, nasolacrimal duct obstruction, headaches, ostiomeatal complex disease and facial numbness. However, presentation of such Patients with recurrent haemoptysis has not been described in the literature so far. We have described a case of an ectopic, supernumerary molar tooth in the maxillary antrum in a Patient who initially presented with haemoptysis. A 45-year-old male presented with a 2-month history of episodic haemoptysis. A pedunculated growth from the inferior nasal turbinate was seen with fibre-optic visualization. …

Nanosized Hydroxyapatite And Other Calcium Phosphates: Chemistry Of Formation And Application As Drug And Gene Delivery Agents, Vuk Uskoković, Dragan Uskoković

Pharmacy Faculty Articles and Research

The first part of this review looks at the fundamental properties of hydroxyapatite (HAP), the basic mineral constituent of mammalian hard tissues, including the physicochemical features that govern its formation by precipitation. A special emphasis is placed on the analysis of qualities of different methods of synthesis and of the phase transformations intrinsic to the formation of HAP following precipitation from aqueous solutions. This serves as an introduction to the second part and the main subject of this review, which relates to the discourse regarding the prospects of fabrication of ultrafine, nanosized particles based on calcium phosphate carriers with various …

Today - November 3, 2010, Loma Linda University

TODAY

Inside this issue:

-- Annual convocation chapel celebrates spiritual roots of Loma Linda University
-- Free flu shots and health screenings offered at LLUMC Family Health Fair
-- LLU Medical Center ophthalmologist named among 'Best Doctors in America'
-- Japanese exchange program enriches GIS at Loma Linda University
-- Wholeness lecture series begins with lesson in personality
-- Marine officer shares his personal story of recovery from addition
-- Doctor of nursing practice program experiences rapid growth
-- Adults needed as subjects for an avocado research study
-- School of Religion hosts roundtable discussion on young Adventists
-- Pharmacy student …

Grown Up Congenital Heart Disease Patient Presenting For Non Cardiac Surgery: Anaesthetic Implications, Mohammad Hamid, Mansoor Ahmed Khan, Mohammad Irfan Akhtar, Hameedullah, Saleemullah, Khalid Samad, Fazal Hameed Khan

Department of Anaesthesia

Congenital heart disease patients surviving to adulthood have increased over the years due to various reasons. These patients are admitted in the hospital for non cardiac surgeries and other procedures more often than normal adult population. Management of grown up congenital heart disease patient presents a challenge during perioperative period for cardiologists, surgeons, intensivists and particularly for the anaesthetist. Management issues include psychological and physiological impact on the patient, complexity of defects, presence of previous palliative procedure, impact of anaesthetic agents on shunting and myocardium, endocarditis prophylaxis and associated extra cardiac anamolies.

Ada News - 11/01/2010, American Dental Association, Publishing Division

ADA News

Established in 1970 as the official newspaper of the American Dental Association, the ADA News serves practicing dentists and others allied to the dental profession in the U.S. and internationally. It is the No. 1 source of news and information about the many benefits and services the ADA delivers to members daily as well as timely information on scientific, social, political and economic developments affecting dentistry and health care.

Admission Systems To Dental School In Europe: A Closer Look At Flanders, Tine Buyse, Filip Lievens, L. Martens

Research Collection Lee Kong Chian School Of Business

Dental education in Europe faces enormous challenges. One deals with the admission to dental school. Although admission procedures vary considerably across Europe, a characteristic of some systems is that the same procedure is used across students who will ultimately pursue different majors (medical or dental). This is based on the assumptions that there is no significant difference in these students' scores and that the requirements for medicine and dentistry are equal. This study examines these assumptions in the admission exam 'Medical and Dental Studies' in Flanders. Students who pass may choose whether they start medical or dental education. Over an …

Healthcare In Cuba, Carmen M. Cusack J.D.

Carmen M Cusack

Poor Americans who lack health-insurance or have little opportunity to access specialized or non-emergency medical treatment in the U.S. should be permitted by the U.S. State Department to spend money in Cuba in order to receive inexpensive medical treatment, and should be allowed to stay (and spend) in Cuba as long as necessary in order to receive inexpensive medical treatment. If Americans were permitted by an exception in the Helms-Burton Act to spend money in Cuba and visit for medical purposes, then Cuba would likely treat these Americans for a very low cost. This can be argued because 1) Cuba …

Today - October 27, 2010, Loma Linda University

TODAY

Inside this issue:

-- 'Who Touched Me?' sculpture unveiled at Loma Linda University
-- Emmy award-winning Loma Linda 360° to resume in November
-- School of Dentistry meets community members during health fair
-- New weight-loss program begins at LLU Drayson Center
-- Former summer research participant Gabriel Linares wins NIH post-doctoral fellowship
-- Major shift takes place in School of Dentistry orientation programs
-- LLU Medical Center employee wins world championship boxing title
-- LLU professor conducts turtle conservation research in Honduras
-- Professor joins LLU School of Pharmacy
-- Community Kids Connection seeks mentors, volunteers, and matching funds …