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The Absence Of Cd20 Messenger Rna In Recurrent Cutaneous B-Cell Lymphoma Following Rituximab Therapy, Yeshwant B. Rawal, Gerard J. Nuovo, Gwyn E. Frambach, Pierluigi Porcu, Robert A. Baiocchi, Cynthia M. Magro Oct 2005

The Absence Of Cd20 Messenger Rna In Recurrent Cutaneous B-Cell Lymphoma Following Rituximab Therapy, Yeshwant B. Rawal, Gerard J. Nuovo, Gwyn E. Frambach, Pierluigi Porcu, Robert A. Baiocchi, Cynthia M. Magro

School of Dentistry Faculty Research and Publications

Background: Rituximab has been used to treat relapsed low-grade or advanced non-Hodgkin's lymphoma since 1997, targeting the CD20 antigen expressed by B cells. Single-agent rituximab therapy is safe and well tolerated. Recurrences showing a loss of CD20 expression following rituximab therapy have been reported.

Methods: Four patients with CD20-positive cutaneous B-cell lymphoma received rituximab therapy with subsequent recurrences. The biopsies were assessed for cytoplasmic CD20 expression; CD20 messenger RNA was also assessed where tissue was available.

Results: Cutaneous relapses occurring within 1.5–3 months following the last dose of rituximab were CD20 negative. In three cases, subsequent relapses showed renewed expression …


Prevention Of Periodontal Diseases, Andrew R. Dentino, Moawia M. Kassab, Erica J. Renner Jul 2005

Prevention Of Periodontal Diseases, Andrew R. Dentino, Moawia M. Kassab, Erica J. Renner

School of Dentistry Faculty Research and Publications

No abstract provided.


Adhesive Fragment Reattachment After Orthodontic Extrusion: A Case Report, S. Burcak Cengiz, Ilken Kocadereli, H. Cem Güngör, Nil Altay Feb 2005

Adhesive Fragment Reattachment After Orthodontic Extrusion: A Case Report, S. Burcak Cengiz, Ilken Kocadereli, H. Cem Güngör, Nil Altay

School of Dentistry Faculty Research and Publications

In the treatment of crown fractures, adhesive fragment reattachment provides a good alternative to other restorative techniques, offering several advantages. The present paper reports a case in which the treatment of a cervical crown fracture was accomplished by reattaching the tooth fragment with a flowable resin composite. Orthodontic root extrusion was performed with a modified Hawley appliance prior to fragment reattachment. The clinical and radiographic results after 2.5 years were successful.


Pilot Survey Of Oral Health-Related Quality Of Life: A Cross-Sectional Study Of Adults In Benin City, Edo State, Nigeria, Christopher Okunseri, Amit Chattopadhyay, R Iván Lugo, Colman Mcgrath Jan 2005

Pilot Survey Of Oral Health-Related Quality Of Life: A Cross-Sectional Study Of Adults In Benin City, Edo State, Nigeria, Christopher Okunseri, Amit Chattopadhyay, R Iván Lugo, Colman Mcgrath

School of Dentistry Faculty Research and Publications

Background

Oral health studies conducted so far in Nigeria have documented prevalence and incidence of dental disease using traditional clinical measures. However none have investigated the use of an oral health-related quality of life (OHRQoL) instrument to document oral health outcomes. The aims of this study are: to describe how oral health affects and impacts quality of life (QoL) and to explore the association between these affects and the oral health care seeking behavior of adults in Benin City, Edo State, Nigeria.

Methods

A cross-sectional survey recruited 356 adults aged 18–64 years from two large hospital outpatient departments and from …