Digital Commons Network^™

Bioresorbable Composite Polymeric Materials For Tissue Engineering Applications, Sakineh Hajebi, Saeed Mohammadi Nasr, Navid Rabiee, Mojtaba Bagherzadeh, Sepideh Ahmadi, Mohammad Rabiee, Mohammadreza Tahriri, Lobat Tayebi, Michael R. Hamblin

School of Dentistry Faculty Research and Publications

This review covers the development of bioresorbable polymeric composites for applications in tissue engineering. Various commercially available bioresorbable polymers are described, with emphasis on recent bioresorbable composites based on natural and synthetic polymers. Bioresorbable polymers contain hydrolyzable bonds, which are subjected to chemical degradation via either reactive hydrolysis or enzyme-catalyzed active hydrolysis. For synthetic polymers, chemical hydrolysis is the most important mode of degradation. The degradation rate can be controlled by varying the molecular weight and crystallinity. Examples of bioresorbable polymers are: polyurethane, poly(D,L)lactide, poly(lactic-co-glycolic) acid, poly(α-hydroxy acids), cross-linked polyester hydrogels, poly(orthoesters), polyanhydrides and polyethylene glycol.

Clinical Long-Term Success Of Contemporary Nano-Filled Resin Composites In Class I And Ii Restorations Cured By Led Or Halogen Light, Torsten Pflaum, Stefan Kranz, Regina Montag, Arndt Guentsch, Andrea Völpel, Robin Mills, Klaus Jandt, Bernd Sigusch

School of Dentistry Faculty Research and Publications

Objectives

The use of LED light-curing units (LED LCUs) for polymerising resin-based composite restorations has become widespread throughout dentistry. Unfortunately, there is a paucity of clinical longitudinal studies that evaluate the comparative efficacy of LED-based polymerisation in direct posterior composite restorations. The aim of the present study was to investigate the performance of class I and II resin composite restorations for two successful composite restorative materials cured with LED versus halogen LCUs.

Methods

One hundred restorations were placed using the nano-filled composites Grandio® or Filtek™ Supremé. The following test groups were established: LED-Grandio® n = 23 (LG), LED-Filtek™ Supremé n …

Nanomagnetic-Mediated Drug Delivery For The Treatment Of Dental Disease, Yadong Ji, Seung K. Choi, Ahmed S. Sultan, Kong Chuncai, Xiaoying Lin, Erfan Dashtimoghadam, Mary Anne Melo, Michael Weir, Huakun Xu, Lobat Tayebi, Ahihong Nie, Didier A. Depireux, Radi Masri

School of Dentistry Faculty Research and Publications

Maintaining the vitality of the dental pulp, the highly innervated and highly vascular, innermost layer of the tooth, is a critical goal of any dental procedure. Upon injury, targeting the pulp with specific therapies is challenging because it is encased in hard tissues. This project describes a method that can effectively deliver therapeutic agents to the pulp. This method relies on the use of nanoparticles that can be actively steered using magnetic forces to the pulp, traveling through naturally occurring channels in the dentin (the middle layer of the tooth). This method can reduce the inflammation of injured pulp and …

Development Of Chitosan/Gelatin/Keratin Composite Containing Hydrocortisone Sodium Succinate As A Buccal Mucoadhesive Patch To Treat Desquamative Gingivitis, Zahra Davoudi, Mohammad Rabiee, Behzad Houshmand, Niloofar Eslahi, Kimia Khoshroo, Morteza Rasoulianboroujeni, Mohammadreza Tahriri, Lobat Tayebi

School of Dentistry Faculty Research and Publications

The aim of this research was to develop chitosan/gelatin/keratin composite containing hydrocortisone sodium succinate as a buccal mucoadhesive patch to treat desquamative gingivitis, which was fabricated through an environmental friendly process. Mucoadhesive films increase the advantage of higher efficiency and drug localization in the affected region. In this research, mucoadhesive films, for the release of hydrocortisone sodium succinate, were prepared using different ratios of chitosan, gelatin and keratin. In the first step, chitosan and gelatin proportions were optimized after evaluating the mechanical properties, swelling capacity, water uptake, stability, and biodegradation of the films. Then, keratin was added at different percentages …

Changes In Composite Toxicity Following Exposure To Pulp Capping Materials, Audra Long

Master's Theses (2009 -)

Introduction: Direct pulp capping involves placing a material over the exposed pulp in order to maintain its vitality. For decades, calcium hydroxide (CH) has served as the gold standard for this purpose, but its toxicity to the pulp may negatively impact treatment outcomes. Mineral Trioxide Aggregate (MTA) has become a popular alternative based partly on its excellent biocompatibility. Pulp-capped teeth are often restored with highly toxic composite materials, but the pulp capping material’s ability to alter these toxic effects has never been investigated. The purpose of this in vitro study is to determine the effects of Dycal, a CH-based cement, …

The Effects Of Different Surface Treatments On The Shear Bond Strength Of Composite Resin To Machined Titanium, Mohammad Sadeq Aljadi

Master's Theses (2009 -)

Purpose: The purpose of this study was to evaluate the shear bond strength between machined titanium and composite resin using different surface treatments.

Materials and Methods: Titanium (Ti-6Al-4V) specimens were ground with 600 grit SiC paper and randomly divided into 6 groups (n=20/group). Group #1 (Control): samples were sandblasted with 110 µm Al₂O₃ for 10 sec. Group #2 (Rocatec): samples were treated with the Rocatec system following the manufacturer's directions but the silanization step was eliminated. Group #3 (Silano Pen): samples were treated with the Silano Pen system. Group #4 (H₂SO₄ etched): samples were …