Open Access. Powered by Scholars. Published by Universities.®
Articles 1 - 1 of 1
Full-Text Articles in Entire DC Network
An Agent Based Model Of Tumor Growth And Response To Radiotherapy, Nicole O'Neil
An Agent Based Model Of Tumor Growth And Response To Radiotherapy, Nicole O'Neil
Theses and Dissertations
An agent based model was developed to examine the growth of a tumor in a healthy cell population. Response to radiation and impact of mutation and bystander effects were studied. In the growth model, the cancer cells proliferated outward becoming invasive. The mass of cancer cells developed a necrotic core. Various treatment protocols of radiation were compared. Timing of treatments was critical to the success of therapy. The event of mutation was rare. When mutation occurred, either unsuccessful treatment or re-growth could result. Multiple rounds of radiation potentially led to increased mutation. Low levels of the bystander effect had little …