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Evaluating The Impact Of An Intervention To Promote Empathy For Patients With Substance Use Disorder In A Rural Emergency Department, Theresa Poling

Graduate Theses, Dissertations, and Problem Reports

Background

Negative attitudes of health professionals towards patients with SUD are common and contribute to suboptimal health care for this marginalized group of patients (Van-Boekel, Brouwers, Van-Weeghel & Garretson, 2013).

Objectives

Promoting empathy in the Emergency Department (ED) has the potential to increase nursing staff’s awareness of their attitudes and perceptions toward patients with SUD, thereby decreasing the stigma associated with addiction and improving patient care and patient outcomes. The rationale for implementing this project was to evaluate a tool to promote empathy. This tool was developed by the student researcher based on a literature search and analysis.

Design

This …

Environmental Regulation Of The Heart: The Role Of Non-Coding Rna And Epigenetics In Influencing Mitochondrial And Cellular Health, Quincy Alexander Hathaway

Graduate Theses, Dissertations, and Problem Reports

The mitochondrion, a small but ubiquitously distributed organelle in the cell, continues to be the focus of many disease pathogeneses, tissue and organ dysfunctions, and other morbidities that occur throughout the body. The purpose of this work was to understand how cardiac mitochondrion are altered in disease and pathological states, specifically in their adaptation to environmentally stimulated regulatory networks, such as epigenetic modifications and promotion/inhibition of non-coding RNAs. Acute stress to mitochondrial regulation (inhalation toxicology) as well as chronic (type 2 diabetes mellitus) was examined. Using a FVB transgenic microRNA-378a mouse knockout model, the cardiovascular impact derived from altering the …

The Potential Promises And Pitfalls Of Using Local Norms For Gifted Identification, Marla S. Hartman

Graduate Theses, Dissertations, and Problem Reports

Who are the gifted? This question has plagued the field since its inception. Historically, gifted education has been predicated on the values of the Caucasian, upper- to middle-class majority. As a result, underrepresentation of students from economically disadvantaged and culturally diverse families have been well documented in the literature and continues to this day. Some scholars have suggested the use of expanded definitions of giftedness to increase participation of students from underrepresented segments of the population. This study used regression and hierarchical linear models to predict the proportion of students identified across various thresholds focusing on how definitions impacted differential …

Review Of Water Allocation Models For West Virginia, Madison Lee Alexis Thompson

Graduate Theses, Dissertations, and Problem Reports

Modeling river basins started gaining in popularity and usage in the western part of the United States in large part due to its extreme droughts. Planning is necessary to sustain the population, industries, and recreational water use year-round. Water allocation modeling is a tool used to aid in the issues that come from managing water resources. This work considers the continuous models that synthesized the hydrologic processes that occur and provides a simulation of past, current, or future conditions.

West Virginia, located on the eastern side of the United States, does not have an extreme drought problem as seen in …

Morphological And Phylogenetic Resolution Of Diplodia Spp., Emerging Canker Pathogens Of Oak (Quercus Spp.), In The United States, Savannah Lyn Ferreira

Graduate Theses, Dissertations, and Problem Reports

In Mediterranean Europe and the United States, oak species (Quercus spp.) have been in a state of declining health and vigor for the past several decades. Several biotic agents have been found to contribute to this decline to varying degrees including Phytophthora cinnamomi and Armillaria spp., both causal agents of root rots, and various insect defoliators. In the U.S., Bretziella fagacearum, the causal agent of oak wilt, has also been implicated. More recently, Diplodia corticola (Dc) and other Diplodia spp. have been implicated in causing dieback and mortality of oak species in Europe and in …

Movement In The Classroom: Contingent Factors Underlying Teacher Change, Annie E. Machamer

Graduate Theses, Dissertations, and Problem Reports

Background: Teachers' use of classroom physical activity (PA) has been found to significantly impact students PA participation, time on task, and academic performance. However, teachers have continued to identify barriers affecting delivery related to professional development opportunities, learning environment, and experiences in practice. An understanding of the connection between these experiences and their impact on teacher change is needed.

Purpose: The purpose of this study was to investigate teachers’ perceptions of specific factors that have influenced their continued implementation of classroom PA. This study provides insight into the teacher perceptions, and aims to identify connections among orientation to learning and …

A Comprehensive Evaluation Of A Home Visitation Program Model's Prenatal Physical Activity Curriculum Modules Delivered Primarily To Low-Income Women, Angela Marie Dyer

Graduate Theses, Dissertations, and Problem Reports

Background. Many low-income pregnant women receive prenatal physical activity (PA) curricula modules through home visitation programs. However, there is a lack of scientific evidence on the structural capacity, processes, and outcomes relating to these modules. Aims. The objective of this dissertation project was to examine the aforementioned in a single home visitation program model - the Maternal Infant Health Outreach Worker (MIHOW) program. More precisely, the aims of this study were to: (Aim 1) examine home visitors’ (i.e., Outreach Workers [OWs]) competencies in implementing the MIHOW program’s prenatal PA curriculum modules (i.e., structural capacity), (Aim 2) …

Accessible Design In Rural Health Care: Usability Profile Of Outpatient Health Care Facilities In Rural West Virginia., Jordan E. Miller

Graduate Theses, Dissertations, and Problem Reports

The Americans with Disabilities Act (ADA) became law in 1990. Since then, research has shown that people with disabilities continue to experience environmental, systematic, and structural barriers to health care. The purpose of this research is to explore the prevalence of barriers in rural West Virginia health facilities and the relationship between building characteristics (like age and purpose) and accessibility. The researcher evaluated ten rural outpatient member-sites of the West Virginia Practice-Based Research Network using a survey to understand building characteristics and a tool to measure essential features for a facility to be considered ‘usable’. Findings included a negative correlation …

Ferritin: An Iron Deficiency Biomarker In Collegiate Female Distance Runners, Ty Bigelow

Graduate Theses, Dissertations, and Problem Reports

Context: Iron deficiency is a concern in distance runners due to the implications that hemoglobin production becomes impaired limiting oxygen uptake and tissue oxidation in the body. Ferritin is a biomarker used to diagnose iron deficiency. The related signs and symptoms of iron deficiency are associated with decreased performance and prolonged recovery. Objective: The purpose of this study was to investigate whether the change in ferritin levels affect measures of performance, measures of recovery, and rate of perceived exertion in female endurance runners. Design: The study was a descriptive longitudinal study. Setting: The study was conducted at a Mid-Atlantic Division …

Elucidating Disease Dynamics In The Biocontrol Of Ailanthus Altissima While Confirming The Host Specificity Of The Vascular Wilt Pathogen Verticillium Nonalfalfae, Kristen L. Wickert

Graduate Theses, Dissertations, and Problem Reports

Ailanthus altissima is a highly invasive exotic tree species entrenched throughout the United States. Since the discovery of a vascular wilt disease of Ailanthus in 2002, caused by the fungus Verticillium nonalfalfae, many studies are investigating its potential as a biocontrol focusing on efficacy, host specificity and disease transmission. This study addresses: the reproductive potential of Ailanthus; if V. dahliae alters Verticillium wilt progression; if hardiness zones influence the individual contributions of two Verticillium spp.; can a unique habitat affect biocontrol efficacy; and can the fungal proteome of V. nonalfalfae allow us to explain differences in host …

Breaking And Remaking The Mason-Dixon Line: Loyalty In Civil War America, 1850-1900, Charles R. Welsko

Graduate Theses, Dissertations, and Problem Reports

Between 1850 and 1900, Americans redefined their interpretation of national identity and loyalty. In the Mid-Atlantic borderland of Maryland, Pennsylvania, Virginia, and West Virginia this change is most evident. With the presence of a free state and slave states in close proximity, white and black Americans of the region experienced the tumult of the Civil War Era first hand. While the boundary between freedom and slavery served as an antebellum battleground over slavery, during the war, the whole region bore witness to divisions between the Union and Confederacy as well as to define what loyalty and nation meant. By exploring …

Adoption And Impact Of Telemental Health On Healthcare Outcomes In The United States, Xiaohui Zhao

Graduate Theses, Dissertations, and Problem Reports

Mental health conditions (MHCs) are the most expensive conditions in the United States (US). The high MHC prevalence coupled with continued undertreatment of MHC has contributed significantly to this high economic burden. Despite policy changes to increase mental health parity and integrate mental and physical healthcare, the shortage of mental health providers remains a significant barrier to mental health (MH) treatment. Telemental health (TMH) has emerged as an alternative care delivery approach to meet the growing demand of MH care and shortages of MH providers. Understanding the adoption of TMH among mental health facilities is critical for informing the broad …

Utilizing The Parts Of Common Food Products As Functional Ingredients Part 1: Separation And Concentration Of Ω-3 Pufa-Rich Phospholipids By Hydration Of Krill Oil Part 2: Functional Properties Of A Concentrated Egg Yolk Protein Powder Using A One-Step Organic Solvent Extraction Process, Casey Lynn Showman

Graduate Theses, Dissertations, and Problem Reports

The food industry separates food products into different parts to better utilize the functional and nutritional benefits of each fraction. The overall focus of this thesis is on separating and utilizing fractions and co-products from food manufacturing as functional ingredients. Therefore, the objective of this research was to 1) evaluate the effectiveness of water degumming to separate omega-3 PUFA-rich phospholipids from other lipids found in krill oil and 2) determine how different organic solvents would affect physiochemical and functional properties of egg yolk protein recovered from spray-dried egg yolk using a novel one-step organic solvent extraction method.

The aim of …

Role Of Extracellular Vesicles In Neuroinflammatory Progression And Mitochondrial Functional Alterations, Ashley E. Russell

Graduate Theses, Dissertations, and Problem Reports

Inflammation within the central nervous system (CNS), termed neuroinflammation, is a defining characteristic of many neuropathological conditions, including Alzheimer’s disease (AD) and stroke. Certain inflammatory mediators activate the transcription factor NF-κB, which induces transcription of many pro-inflammatory genes, including miR-34a and miR-146a. Several target candidate genes of these miRNAs encode for proteins of the mitochondrial electron transport chain. In our studies, we demonstrate that in response to inflammatory stimuli, such as TNF-α, the expression of miR-34a and -146a is significantly increased in several CNS cell types, and in their secreted extracellular vesicles (EVs). Exposure to TNF-α-derived EVs significantly increases cellular …

Promoting Sense Of Belonging And Interest In Geosciences Among Undergraduate Women Through Mentoring, Wenyi Du

Graduate Theses, Dissertations, and Problem Reports

The purpose of this study is to investigate whether students’ university sense of belonging mediates the relationship between mentor network diversity and students’ interest development among undergraduate women in STEM majors. The sample for this study was consisted of 277 undergraduate women majoring in a STEM discipline with initial interests in geosciences across nine universities within the United States. A regression-based mediation analysis was performed using the Hayes’ (2013) macro to test the indirect effect of mentor support on interest through university sense of belonging. Consistent with our hypothesis, the analysis revealed a statistically significant and positive indirect effect of …

The Relationship Between Social Skills And Problem Behaviors In Adolescent Males With Autism Spectrum Disorders, Amanda Armstrong Randall

Graduate Theses, Dissertations, and Problem Reports

Adolescent males with autism spectrum disorder commonly display an increased prevalence of problem behaviors and persistent deficits in social skills when compared to their typically developing peers. The present study deployed a single subject, multiple-baseline design to investigate the use of the social skills training program Super Skills: A Social Skills Group Program for Children with Asperger Syndrome, High-Functioning Autism and Related Challengesto promote enhanced social skills and minimize problem behaviors. Two groups of adolescent males with autism (N = 6) participated in weekly social skills training groups also containing typically developing peers (N = 3) once …

A Coordination-Based Approach To Subnational Variations In Split-Ticket Voting: The Case Of Ghana 1996-2016, Samuel Kofi Darkwa

Graduate Theses, Dissertations, and Problem Reports

This dissertation seeks to explain the causes of split-ticket voting (skirt and blouse voting) in emerging democracies like Ghana. The analysis carried out here has been approached at three levels. This is because voters’ decisions in the voting booth are affected by factors within the larger political environment which are often beyond the individual voter. Thus, the three approaches employed here consider individual-level, constituency-level, and elite-level factors that affect the phenomenon. In each case different datasets were used to examine split-ticket voting. The analysis reveals that the individual-level factors (demographic characteristics and political information variables) are weak in explaining ticket …

Immunity-Based Framework For Autonomous Flight In Gps-Challenged Environment, Mohanad Al Nuaimi

Graduate Theses, Dissertations, and Problem Reports

In this research, the artificial immune system (AIS) paradigm is used for the development of a conceptual framework for autonomous flight when vehicle position and velocity are not available from direct sources such as the global navigation satellite systems or external landmarks and systems. The AIS is expected to provide corrections of velocity and position estimations that are only based on the outputs of onboard inertial measurement units (IMU). The AIS comprises sets of artificial memory cells that simulate the function of memory T- and B-cells in the biological immune system of vertebrates. The innate immune system uses information about …

Thermal Performance Of Growth At Consumption Maximum (C-Max) And Routine Metabolic Rate (Rmr) In Brook Trout Salvelinus Fontinalis From Four Populations In Central Appalachia, Cory Michael Hartman

Graduate Theses, Dissertations, and Problem Reports

Growth of an individual is the end result of many physiological processes stemming from the consumption of food items. These processes can be influenced by many variables including temperature. Current bioenergetics models for Brook Trout Salvelinus fontinalis suggest growth increases with temperature until an inflection point of 20.2°C. With a warming climate, and water temperatures expected to rise, the ability of a population to adapt to the warming environment is crucial to the survival of the species. For this study we sought to see how spatial variation would influence the specific consumption, conversion efficiency, and specific growth at consumption maximum …

Assessment Of Fracture Resistance Of Maxillary First Molars After Root Canal Preparation Using Three Different Rotary Instruments (V-Taper, Protaper, Vortex Blue): Finite Element Analysis, Mehran Malakpour

Graduate Theses, Dissertations, and Problem Reports

Introduction: Long term success of endodontically treated teeth has been one of the most challenging aspects of the field of endodontics due to reduced fracture resistance of these teeth. Recently, researchers have heightened focus on conservative endodontics in order to sustain the tooth integrity, and reduce factors impacting the fracture resistance of endodontically treated teeth. As a result, rotary instrument manufacturers have developed files that have a minimal effect on original root canal anatomy. This study used Finite Element Analysis to investigate the dental biomechanical effect of rotary instrumentation during root canal therapy. The aim of this study is to …

Autonomous Systems With Reuse: A Survey On The State-Of-The-Practice, Denny Laverne Hood Iii

Graduate Theses, Dissertations, and Problem Reports

This problem report presents the results of an anonymous online survey that was used to collect information about software systems that use model-based software engineering, contain autonomy and where software reuse plays an important role. Recent advancements in computation ability and the emergence of decision-making algorithms have increased interest in and use of autonomy in applications areas such as aeronautics, automotive, military, and space industries. In these application domains, autonomy is used to reduce costs, reduce reaction times, and improve performance. Due to the emerging nature of autonomy, very little research has been done regarding the level of autonomy of …

A Sociopolitical Perspective To Understand When And Why Supervisors Endorse And Implement Employees’ Suggested Changes, Huaizhong Chen

Graduate Theses, Dissertations, and Problem Reports

When employees make suggestions for changes to their supervisors, they are providing raw materials potentially critical to the organization’s continuous improvement and adaptation. However, research suggests that supervisors do not always react favorably to employee voice behavior. The purpose of this study is to unravel the mediating and moderating mechanisms that can explain when and why employee voice behavior leads to supervisor endorsement and implementation. Specifically, taking a sociopolitical perspective, I argued that supervisor motive attributions for employee voice behavior can explain the extent to which supervisors endorse and subsequently implement employee voice. Furthermore, I argued that the mediating effects …

A Timeless Ritual, Luke Thomas Doyle

Graduate Theses, Dissertations, and Problem Reports

This written thesis is the supporting documentation for A Timeless Ritual, my Master of Fine Arts thesis exhibition. The exhibition seeks to define my expression of aesthetics through utilitarian vessels to create a sense of nostalgia with the user my mimicking industrial objects.

The research pertaining to my thesis explores the interactions between object and user. A patina layered over time evokes a sense of age, weathered memories of a time once lived. I look for these subtle nuances in form. Borrowing an aesthetic from manufactured products and reviving it in a domestic space is where my pots takes life. …

Optimization Of Engineered Super Donor Strains Of Cryphonectria Parasitica To Reduce Canker Expansion In A Forest Setting, Amy Michelle Metheny

Graduate Theses, Dissertations, and Problem Reports

Chestnut blight, caused by the non-native fungus Cryphonectria parasitica, has decimated American chestnut (Castanea dentata) populations throughout the eastern U.S. over the last century. Biological control of blight, termed hypovirulence, has emerged naturally in the form of a debilitating hypovirus transmitted through hyphal anastomosis among vegetatively compatible C. parasitica strains. Six unlinked vegetative incompatibility (vic) loci regulate hyphal anastomosis and thus, hypovirus transmission, which has limited biocontrol efficacy in genotypically diverse communities. Recently, four of six vic loci have been disrupted to engineer two “super donor” or SD strains. In combining these strains, enhanced transmission …

The Perception Of Management Support For Patient Safety After The Implementation Of A System Change, Janice M. Smith

Graduate Theses, Dissertations, and Problem Reports

Problem Statement Leadership scores on the AHRQ Hospital Patient Safety Culture Survey at a 268 bed teaching, acute care, nonprofit, non-governmental hospital in the South Atlantic Region of the United states have been decreasing for the past seven years. In those years there has been no plan to improve the scores. Safety scores published for this facility on public websites are mediocre or poor.

Theoretical Framework The Plan-Do-Study-Act (PDSA) conceptual model for rapid cycle improvement served as a foundation for the project. The model supported the project well with a plan, do (test the plan), study (analyze the results), act …

Defining The Late Style Of Johannes Brahms: A Study Of The Late Songs, Natilan Casey-Ann Crutcher

Graduate Theses, Dissertations, and Problem Reports

Johannes Brahms has long been viewed as a central figure in the Classical tradition during a period when the standards of this tradition were being altered and abandoned. His resistance to innovation creates some difficulty when trying to pinpoint his "late style", and how he fits into the late style concept. While existing scholarship on Brahms's late style tends to focus on his chamber works, this document focuses on his late Lieder. This document proves a study of Brahms's literary considerations, a comparison of his early and late songs, and a comparison between Brahms and some of his contemporaries. In …

The Acute Effect Of Propanil On Reproductive Hormones, Ovarian Gene Expression And Splenic Cells In C57bl/6 Female Mice, Malia Danielle Berg

Graduate Theses, Dissertations, and Problem Reports

Earlier evidence indicates exposure to propanil, a post-emergent herbicide used on rice and wheat fields, increases the number of antibody-secreting cells (ASC) in the spleen of mice after immunization with heat-killed Streptococcus pneumoniae (HKSP, 2x10⁸ CFU). Interestingly, an intact hypothalamic-pituitary-gonadal (HPG) axis is required for this immune response assessed on day 7-10 after immunization in female mice. Hence, an overarching premise is that propanil arbitrates the connection between the reproductive and immune system by altering the concentration of hormones involved in the HPG axis, which may then affect the populations of splenic cells. Hypotheses were tested with C57Bl/6 female …

Kidney Ailment Prediction Under Data Imbalance, Ranaa Mahveen

Graduate Theses, Dissertations, and Problem Reports

Chronic Kidney Disease (CKD) is the leading cause for kidney failure. It is a global health problem affecting approximately 10% of the world population and about 15% of US adults. Chronic Kidney Diseases do not generally show any disease specific symptoms in early stages thus it is hard to detect and prevent such diseases. Early detection and classification are the key factors in managing Chronic Kidney Diseases.

In this thesis, we propose a new machine learning technique for Kidney Ailment Prediction. We focus on two key issues in machine learning, especially in its application to disease prediction. One is related …

Enhancing Water Stress Tolerance In Floriculture Crops, Suejin Park

Graduate Theses, Dissertations, and Problem Reports

Water deficit is one of the major constraints on plant growth and development, causing reduction of crop productivity. To minimize water loss, among many adaptation strategies, plants close their stomata to reduce transpiration. The stomatal closure is regulated by light, internal CO2 concentration, and plant hormones, mainly abscisic acid. Plants’ response mechanisms to water deficit are complex processes involving numerous genes and various signaling pathways. Floriculture crops are often exposed to water deficit during shipping and retailing, and these periods often result in damaged crops and profit loss. Understanding of plant responses to water deficit stress will provide us an …

The Dirt Of Development: Nature's Role In Social-Emotional Development And Parent-Child Connectedness, Hayley Johanna Lindsey

Graduate Theses, Dissertations, and Problem Reports

The purpose of this study was to examine associations between nature connectedness, parent-child connectedness, and the development of prosocial behavior. Nature connectedness pertains to the strong emotional affinity towards the natural environment and is linked with happiness, stress reduction, and good health. Prosocial behavior refers to actions or behaviors done with the intent to help others. This study consisted of 467 parent-informants that gathered information on the parent’s nature connectedness, the child’s nature connectedness, the parent-child connectedness, and the child prosocial behavior. Gaps in the literature were addressed by analyzing the role that parent nature connectedness has in predicting child …