Digital Commons Network^™

Fast Fourier Transforms Over Prime Fields Of Large Characteristic And Their Implementation On Graphics Processing Units, Davood Mohajerani

Electronic Thesis and Dissertation Repository

Prime field arithmetic plays a central role in computer algebra and supports computation in Galois fields which are essential to coding theory and cryptography algorithms. The prime fields that are used in computer algebra systems, in particular in the implementation of modular methods, are often of small characteristic, that is, based on prime numbers that fit on a machine word. Increasing precision beyond the machine word size can be done via the Chinese Remaindering Theorem or Hensel Lemma. In this thesis, we consider prime fields of large characteristic, typically fitting on n machine words, where n is a power of …

Physiological And Behavioral Evidence Of Auditory Processing Deficit In Children Suspected Of Auditory Processing Disorder, Sangamanatha Ankmnal Veeranna

Electronic Thesis and Dissertation Repository

A series of studies were carried out to examine the neural and behavioral processing of acoustic stimuli in children with suspected auditory processing disorder (sAPD).

The click-evoked auditory brainstem responses recorded from children with sAPD and adults were analyzed using traditional clinical measures and detailed analysis seeking to explore the separate contributions of axonal conduction and synaptic transmission. Clinical measures revealed significant prolongation of absolute latencies and interwave intervals in children with sAPD compared to adults. Examination of responses delineating axonal vs. synaptic transmission showed frequent delays in synaptic factors and fewer instances of delays related to axonal conduction in …

New Insights Into Signal Detection Of The Effects Of Exposures During Pregnancy, Fatma Etwel

Electronic Thesis and Dissertation Repository

There is inadequate information on the fetal safety of drugs during pregnancy for the majority of marketed drugs. It is challenging to examine the safety and efficacy of drugs during pregnancy due to the ethical issues of exposing unborn babies to these chemicals. It often takes many years before associations between a drug and its safety, efficacy, and toxicity in pregnancy can be established. This thesis will examine strategies in signal detection of the effects of drug exposures during pregnancy.

Meta-analyses have become useful in the area of clinical teratology. Observational studies provide the main source of information in these …

The Truth And Reconciliation Commission Of Canada And Crown-Aboriginal Relations, Timothy E.M. Vine

Electronic Thesis and Dissertation Repository

The Indian Residential School system was one of the most visible instances of a broader colonial project that sought to destroy Aboriginal difference in Canada and overthrow a relationship based on treaties and mutual respect. As part of an out-of-court settlement of several class action law suits by school survivors against the federal government and churches, the Truth and Reconciliation Commission of Canada was tasked with setting a historic record of the effects of the residential schools and fostering reconciliation between the parties to the settlement (including Aboriginal plaintiffs, the Government of Canada, the Roman Catholic Church, Anglican Church, United …

Pdz Protein Regulation Of Β-Arrestin Recruitment And Gpcr Trafficking, Sarah Gupta

Electronic Thesis and Dissertation Repository

β-arrestins are versatile adaptor proteins that play a vital role in regulation of G protein coupled receptor (GPCR) trafficking and signalling properties. PDZ proteins have previously been shown to modulate β-arrestin2 recruitment and receptor internalization for many GPCRs including Corticotropin-Releasing Factor Receptor 1 (CRFR1), a receptor whose antagonists have been shown to demonstrate both anxiolytic- and antidepressant-like effects. Further characterization of the interplay between β-arrestins and PDZ proteins may aid in determining a potential mechanism for PDZ protein regulation of GPCR trafficking. Our findings suggest that PDZ proteins PSD-95, MAGI1, and PDZK1 complex with β-arrestin2 by interacting via the PDZ …

Liquid Phase Nano Metal Catalyzed Dechlorination Of Chlorinated Organic Compounds, Omneya El-Sharnouby

Electronic Thesis and Dissertation Repository

1,2-Dichloroethane (1,2-DCA) is among the most prevalent groundwater chlorinated organic compounds (COCs) found at hazardous sites throughout the world. Given its pervasive contamination and adverse health effects, there is considerable interest in developing novel remediation technologies for successfully treating 1,2-DCA along with other COCs from water sources. Chemical reduction by nano zero valent iron (monometallic (nZVI) or bimetallic (Pd-nZVI)) has proven to be a successful field applicable technology, yet it has failed in degrading such a recalcitrant compound as 1,2-DCA.

In this study, the development of a field applicable nano metal based technology capable of degrading 1,2-DCA was carried out. …

Analysis Of 3d Cone-Beam Ct Image Reconstruction Performance On A Fpga, Devin Held

Electronic Thesis and Dissertation Repository

Efficient and accurate tomographic image reconstruction has been an intensive topic of research due to the increasing everyday usage in areas such as radiology, biology, and materials science. Computed tomography (CT) scans are used to analyze internal structures through capture of x-ray images. Cone-beam CT scans project a cone-shaped x-ray to capture 2D image data from a single focal point, rotating around the object. CT scans are prone to multiple artifacts, including motion blur, streaks, and pixel irregularities, therefore must be run through image reconstruction software to reduce visual artifacts. The most common algorithm used is the Feldkamp, Davis, and …

Nanoscale Thermal And Electronic Properties Of Thin Films Of Graphene And Organic Polyradicals, Sabastine Chukwuemeka Ezugwu

Electronic Thesis and Dissertation Repository

Ultrathin film materials have attracted significant attention in light of their potential applications in very large scale integrated electronics and data storage. For instance, the amount of data that can be addressed and stored in a memory device scales inversely with the thinness of the active layer of these components. In our thesis, we have developed a suite of scanning-probe and nano-optical techniques focused on understanding the electronic surface properties and the thermal conductivity of ultrathin materials. We discuss a few specific examples in which we applied these techniques towards improved performance of thin films of graphene and organic polyradicals …

The Association Between Oxidative Stress, Cellular Differentiation And Galectins In Human Promyelocytic Leukemia Cells (Hl-60), James R. Vinnai

Electronic Thesis and Dissertation Repository

Galectins are a group of β-galactoside-binding proteins involved in different cellular processes including stress responses and differentiation. The role and expression of galectins under oxidative stress and during neutrophilic differentiation was examined in HL-60 cells. Galectin gene (LGALS), and galectin protein expression were determined using RT-qPCR and immunoblotting, respectively. Neutrophilic differentiation was measured via a spectrofluorometric assay. DNA methylation and JNK signaling were investigated as galectin regulatory mechanisms. Menadione-induced oxidative stress, DMSO-induced differentiation, DNA hypomethylation and JNK signaling all promoted similar galectin expression profiles. Antioxidant N-acetylcysteine attenuated the menadione-induced galectin expression but only partially attenuated DMSO-induced galectin expression. …

Self-Disclosure Among Male Survivors Of Child Sexual Abuse: Service Providers’ Perspective, Marudan Sivagurunathan

Electronic Thesis and Dissertation Repository

Previous research regarding child sexual abuse (CSA) indicates significant gender differences in disclosure rates: specifically, males are less likely to disclose their child sexual abuse in comparison to females. CSA can have lasting impact on a child’s emotional, physical, and psychological wellbeing. Trauma studies show support and early intervention is necessary for CSA survivors to re-establish a sense of safety and to experience better quality of life. Service providers play a key role in providing care and support for male CSA survivors. However, little is known about service providers, who work with male CSA survivors, and their perceptions and attitudes …

Evidence Of A Role For G Protein Signaling Modulator 3 In Cell Division, Drew C. Wallace

Electronic Thesis and Dissertation Repository

Components of G protein-mediated signaling are associated with positioning and orienting the mitotic spindle in the process of cell division. However, a functional role for G protein signaling modulator 3 (GPSM3) in cell division has yet to be defined. The purpose of this study was to investigate a potential role for GPSM3 in cell division. Vascular smooth muscle cells (VSMCs) from Wistar-Kyoto (WKY) and spontaneously hypertensive (SHR) rats, that are known to express GPSM3, were used as a model system. Here I report that GPSM3 mRNA and protein levels varied during different stages of the cell cycle in SHR VSMCs. …

Study Of Mobile Robot Operations Related To Lunar Exploration, Matthew Cross

Electronic Thesis and Dissertation Repository

Mobile robots extend the reach of exploration in environments unsuitable, or unreachable, by humans. Far-reaching environments, such as the south lunar pole, exhibit lighting conditions that are challenging for optical imagery required for mobile robot navigation. Terrain conditions also impact the operation of mobile robots; distinguishing terrain types prior to physical contact can improve hazard avoidance.

This thesis presents the conclusions of a trade-off that uses the results from two studies related to operating mobile robots at the lunar south pole. The lunar south pole presents engineering design challenges for both tele-operation and lidar-based autonomous navigation in the context of …

Measuring Brain Serine With Proton Magnetic Resonance Spectroscopy At 3.0 Tesla, Homa Javadzadeh

Electronic Thesis and Dissertation Repository

Proton magnetic resonance spectroscopy (MRS) non-invasively measures regional human brain chemistry in vivo, providing concentration estimates for several metabolites in a pre-selected region of interest. MRS has been applied to investigations of disease-related metabolic and neurochemical alterations in schizophrenia since the early 90’s.

The objective of this research is to implement a metabolite-selective MRS method to quantify endogenous concentrations of human brain serine. Serine is a naturally-occurring amino acid and an important co-modulator of the N-Methyl D-aspartic Acid (NMDA) glutamate receptor. Glutamate abnormalities have been implicated in the pathophysiology of schizophrenia, especially its so-called negative and cognitive symptoms, which can …

Hospital Menu Assessment Of Nutrient Composition And Patient Satisfaction, Susan Greig

Electronic Thesis and Dissertation Repository

Patient satisfaction with menu items enhances intake, and adequate intake of nutrients contained within hospital menus is required for recovery. A survey of foodservice leaders in Ontario hospitals determined the frequency and methods used to assess patient satisfaction with, and the nutritional composition of, menus. From this cross sectional study emerged themes, complemented by quantitative data that demonstrated gaps in practice. Findings suggest that over half of hospitals surveyed assessed regular menus for nutritional adequacy; 53 percent assessed therapeutic menus and 44 percent assessed texture modified menus. This differs from hospitals governing long term care facilities in which 75 percent …

Examining The Impacts Of Wife Abuse And Child Abuse On Saudi Women’S Mental And Physical Health, Eman Alhalal

Electronic Thesis and Dissertation Repository

Research has not extensively examined the contextual mechanisms by which Intimate Partner Violence (IPV) and child abuse lead to chronic pain. Post-traumatic Stress Disorder (PTSD) and depressive symptoms overlap, yet, it is not clear whether they function in unique ways as mediators of the relationships of abuse with chronic pain. Thus, the purposes of this study were to: a) test a causal model that explains the mechanisms by which severity of child abuse and wife abuse affect chronic pain among Saudi women, and the mediating role of symptoms of depression and PTSD and perceived family support and, b) advance the …

Investigation Of Grouted Dowel Connection For Precast Concrete Wall Construction, Douglas J. Provost-Smith

Electronic Thesis and Dissertation Repository

The grouted dowel connection is a simple and cost-effective connection used in many precast concrete structural systems. The required dowel length is currently designed as a regular bar in reinforced concrete, which underestimates the bond strength, thus resulting in excessive connection lengths. Furthermore, precast wall construction continues throughout cold weather, where in-situ heating of the grout used in the grouted dowel connections is usually conducted for short periods of time. Hence, early-age exposure to subfreezing conditions may affect the quality of the grout and subsequently the bond strength of the connection, which can compromise structural integrity.

In this thesis, full-scale …

Producing A Subunit Vaccine For Porcine Epidemic Diarrhea Virus, Zayn Khamis

Electronic Thesis and Dissertation Repository

Porcine epidemic diarrhea virus (PEDv) causes disease and mortality to piglets worldwide. Most vaccines used to combat the disease have been ineffective live attenuated virus vaccines. The goal of this project was to produce a plant-made subunit vaccine based off the membrane protein of the virus. This is the first time this protein has been produced in plants. An elastin-like polypeptide fusion membrane protein accumulated up to 0.8 mg/g of fresh leaf weight when transiently expressed in Nicotiana benthamiana. Virus-like particles were also produced for the first time for PEDv, and were able to form with just the membrane …

Physiological And Psychological Responses Of Surgeons And Trainees, Sarantis Abatzoglou

Electronic Thesis and Dissertation Repository

Performing surgical procedures can increase the physiological stress and mental strain experienced by practicing surgeons and their trainees. This may negatively affect work and learning capacity and quality of patient care by increasing the incidence of burnout, sleep disorders, fatigue and other negative behaviours such as substance abuse. This study aimed to compare the physiological and psychological responses of similar clinical situations between orthopaedic surgeons and their clinical fellows. An observational prospective cohort study was performed in that matter. Our results showed overall increased physiological responses of the fellows during surgery days compared to the clinic days. On the contrary, …

Beyond The Edge Of The Planted Field: Exploring Community-Based Environmental Education, And Invisible Losses In Settler And Indigenous Cultural Contexts, Samantha Da Rosa Holmes

Electronic Thesis and Dissertation Repository

The Walpole Island Land Trust and the Sydenham Field Naturalists came together for a focus group at the Walpole Island Heritage Centre and spoke of the relevance environmental education plays in the awareness of a shared history between communities from separate cultural contexts. From the focus group this research is able to contextualize the conversation between a non-Indigenous and an Indigenous community-based environmental organization, and their focus on the relationship between people, place, and history. The context of the conversation being the colonial legacies of land use management and educational practices and how these institutions prolong the effect of invisible …

In Mold Flow Of Long Fibers In Compression Molding Process, Gleb Meirson

Electronic Thesis and Dissertation Repository

Long Fiber Thermoplastics (LFT) are promising new materials with high physical properties and low density. These high properties are obtained by embedding very long fibers (~100 mm) into a thermoplastic matrix. Such a high fiber length dictates the use of a compression molding process for manufacturing as the length of discontinuous fibers in injection molding is limited by pellet length.

LFT composites are of great interest for the automotive industry. These materials are already used in some interior and exterior car parts such as bumpers, seat structures, door module etc. This research is inspired by the desire to manufacture load …

Synthesis Of Metal-Containing Phosphines And Their Use In Coordination, Polymer, And Materials Chemistry, Amir Rabiee Kenaree

Electronic Thesis and Dissertation Repository

This thesis describes the investigation of a novel strategy for the synthesis of metal-containing small molecules, polymers, and nanomaterials. In this context, a new family of air-stable, homo- and heterometallic primary, secondary, and tertiary phosphines were prepared via the radical-initiated hydrophosphination reaction of PH₃ with vinylferrocene and/or vinylruthenocene. The full characterization of the phosphines confirmed their targeted structures and proved that the properties of the starting metallocenes are reflected in those of the resulting phosphines.

To study the coordination behavior of this family of phosphines, primary, secondary, and tertiary ethylferrocene phosphines were reacted with Group 6 metal carbonyl adducts …

Modelling And Analysis Of Smart Grids For Critical Data Communication, Abdulfattah Noorwali

Electronic Thesis and Dissertation Repository

Practical models for the subnetworks of smart grid are presented and analyzed. Critical packet-delay bounds for these subnetworks are determined, with the overall objective of identifying parameters that would help in the design of smart grid with least end-to-end delay.

A single-server non-preemptive queueing model with prioritized critical packets is presented for Home Area Network (HAN). Closed-form expressions for critical packet delay are derived and illustrated as a function of: i) critical packet arrival rate, ii) service rate, iii) utilization factor, and iv) rate of arrival of non-critical packets. Next, wireless HANs using FDMA and TDMA are presented. Upper and …

Regulatory Compliance-Oriented Impediments And Associated Effort Estimation Metrics In Requirements Engineering For Contractual Systems Engineering Projects, Md Rashed I. Nekvi

Electronic Thesis and Dissertation Repository

Large-scale contractual systems engineering projects often need to comply with a myriad of government regulations and standards as part of contractual fulfillment. A key activity in the requirements engineering (RE) process for such a project is to elicit appropriate requirements from the regulations and standards that apply to the target system. However, there are impediments in achieving compliance due to such factors as: the voluminous contract and its high-level specifications, large number of regulatory documents, and multiple domains of the system. Little empirical research has been conducted on developing a shared understanding of the compliance-oriented complexities involved in such projects, …

Exploring The Experiences Of Muslim Students In An Urban Ontario Public School, Asma Ahmed

Electronic Thesis and Dissertation Repository

This dissertation explores the experiences of Muslim students in an urban public high school in Ontario with a reputation of having a large Muslim student presence. Much of the studies and surveys involving Islam and Muslims make evident that Islam is the most misunderstood religion in the world. Therefore, Muslims in the West are a “poorly understood” minority group (Environics Institute, 2016). While other ethnic or racial minorities feel moderately comfortable defending themselves and their groups, and asserting their identities, Muslim youth “face qualitatively different identity tasks than do many of their peers”, largely due to feelings of “being under …

Leadership Practices Of Principals Of Selected Public Secondary Schools In Kathmandu, Nepal, Shankar Singh

Electronic Thesis and Dissertation Repository

Academic performance of students from most of the public schools in Nepal is not satisfactory. However, there are a few public schools consistently performing well despite similar students’ and teachers’ backgrounds, infrastructure and resources. This study explored how principals’ understandings and practices of their leadership role may have influenced students’ learning.

For this study five higher performing and five lower performing schools from Kathmandu Metropolitan City (KMC) were chosen. In-depth interviews and separate focus group discussions were conducted with the principals. Findings were analyzed under six dimensions of effective school leadership identified from the literature: (a) vision building and goal …

Probiotic Yoghourt For Health, Nutrition And Women's Empowerment In Kenya: A Community-Based Approach, Ellena Andoniou

Electronic Thesis and Dissertation Repository

The dissertation aims to examine the impacts of probiotic yoghourt on health, nutrition and women’s empowerment within the context of HIV/AIDS in Kenya. Mixed methods that combine quantiative and qualitative approaches are used to understand the effects of probiotic yoghourt on the health, nutrition and quality of life for men and women. Results of the quantiative analysis (n=227) demonstrated that the probiotic yoghourt confers a variety of health benefits – physiological (fewer urogenital conditions and digestive problems; reduced dependence on medical treatment), and psychological (perceived improvements with bodily appearance, felt an increased meaningfulness with life). Results of the qualitative analysis …

The Efficacy Of Bionate As An Articulating Surface For Joint Hemiarthroplasty, Sarah Dedecker

Electronic Thesis and Dissertation Repository

Hemiarthroplasty procedures replace the diseased side of the joint with an implant to maximize bone preservation while maintaining more native anatomy than a total joint replacement. Even though hemiarthroplasty procedures have been clinically successful, they cause progressive cartilage damage over time due to the use of relatively stiff metallic implant materials. This work investigates the role of low moduli implant material on implant-cartilage contact mechanics and early in vitro cartilage wear. A finite element simulation was developed to assess the effect of low moduli implants in the range of 0.015-0.288 GPa on contact mechanics. Higher contact area and lower peak …

The Work Of Elementary Principals In Supporting New Teachers In Ontario, Publicly-Funded, English Speaking Schools, Jennifer M. Gonyou-Brown

Electronic Thesis and Dissertation Repository

Teachers benefit from instructional, emotional, institutional and physical supports in their early years of practice (Lipton & Wellman, 2003). Yet, with a teacher surplus in Ontario, many early career teachers (ECTs) spend years in transient, short-term work prior to qualifying for the New Teacher Induction Program (NTIP). As school leaders, Ontario elementary principals develop and facilitate supports for the ECTs in their school. However, principals have identified their workloads to be demanding and intensifying (Pollock, 2014b). ECT support development is one of many responsibilities that principals undertake in their work.

This qualitative study employed semi-structured interviews with twelve elementary principals …

The Effect Of The Gekotm Device On Post Kidney And Pancreatic Transplantation Leg Edema, Bijad Alharbi

Electronic Thesis and Dissertation Repository

Introduction: Kidney and pancreas transplant recipients risk thromboembolism and lower limb edema due to immobility and fluid shift after surgery. Intermittent pneumatic compression (IPC) devices + hromboembolic deterrent (TED stockings) are used to mitigate these risks. However, they risk peroneal nerve injury, discomfort, excessive heat and sweating under the cuffs. The Geko TM device, is an internally powered calf neuromuscular stimulator, shown to have beneficial effects in improving blood flow and skin capillary perfusion. Its role in transplantation has not previously been assessed. Our objective was to prospectively evaluate the effects of IPC+TED stocking and the Geko TM devices on …

Safe Haptics-Enabled Patient-Robot Interaction For Robotic And Telerobotic Rehabilitation Of Neuromuscular Disorders: Control Design And Analysis, Seyed Farokh Atashzar

Electronic Thesis and Dissertation Repository

Motivation: Current statistics show that the population of seniors and the incidence rate of age-related neuromuscular disorders are rapidly increasing worldwide. Improving medical care is likely to increase the survival rate but will result in even more patients in need of Assistive, Rehabilitation and Assessment (ARA) services for extended periods which will place a significant burden on the world's healthcare systems. In many cases, the only alternative is limited and often delayed outpatient therapy. The situation will be worse for patients in remote areas. One potential solution is to develop technologies that provide efficient and safe means of in-hospital and …