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An Fe (Iii) - Initiated Oxidase Reaction With Ferroxidase-Ii, Glenn Alexander Hegamyer
An Fe (Iii) - Initiated Oxidase Reaction With Ferroxidase-Ii, Glenn Alexander Hegamyer
Master's Theses
A reaction involving iron as an intermediary electron carrier for the coupling of electron transfer from an endogenous substrate to ferroxidase-I has been proposed.
The enzymic nature of the reacti on has been established and studies with iron chelating agents have demonstrated the involvement of Fe(III). The kinetic parameters of ferroxidase-11 with Fe (lll) were found to be quite similar to those previously established for Fe(Il). The participation by the copper associated with ferroxi dase-11 was ascertained by use of the copper chelating agent, diethyl -di thio-carbamate .
A variety of substances normally found in blood were surveyed as possible …