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Efficient Algorithms For Solving Facility Problems With Disruptions, Kaike Zhang
Efficient Algorithms For Solving Facility Problems With Disruptions, Kaike Zhang
Doctoral Dissertations
This study investigates facility location problems in the presence of facility disruptions. Two types of problems are investigated. Firstly, we study a facility location problem considering random disruptions. Secondly, we study a facility fortification problem considering disruptions caused by random failures and intelligent attacks.We first study a reliable facility location problem in which facilities are faced with the risk of random disruptions. In the literature, reliable facility location models and solution methods have been proposed under different assumptions of the disruption distribution. In most of these models, the disruption distribution is assumed to be completely known, that is, the disruptions …
A Knowledge Assessment Of Prescription Drug Use Among Student-Athletes At A Southeastern College, Marcus L. Amos
A Knowledge Assessment Of Prescription Drug Use Among Student-Athletes At A Southeastern College, Marcus L. Amos
Doctoral Dissertations
This study examined prescription drug use at a small Division III college in the Southeast. Prescription drug use and misuse is a documented trend among college students. Medication therapy due to injuries is a common means of rehabilitation in sports. Because of this, there have been recent incidences documented in which student-athletes have become victims of accidental drug overdoses, and in some cases, have resulted in their death. In this study, areas examined were the awareness of the culture of prescription drug use among student-athletes, personal use of prescription drugs among student-athletes, and personal knowledge and awareness about prescription drug …
Expanding Secondary Science Teachers' Instructional Practice To Include English Learners Through Professional Learning Communities, Betty R. Thomason
Expanding Secondary Science Teachers' Instructional Practice To Include English Learners Through Professional Learning Communities, Betty R. Thomason
Doctoral Dissertations
English Learners (ELs) are the fastest growing subset of the population in U. S. k-12 schools. ELs are students whose primary language is one other than English and who qualify for specialized services based on an English language proficiency test (Francis, Rivera, Lesaux, Kieffer & Rivera, 2006). One popular approach for supporting ELs academically is the inclusion model (Reeves, 2004). The inclusion method places ELs in classes with Native English Speakers (NES) in which teachers are required to teach English and content to ELs and grade level content to NESs. However, due to the failure of many pre-service programs, teachers …
A Deep Breathing Intervention For Stress Reduction In 5-Year-Old Children, Tara Jean Veerman
A Deep Breathing Intervention For Stress Reduction In 5-Year-Old Children, Tara Jean Veerman
Doctoral Dissertations
This multi-manuscript dissertation concentrates on child stress, an important area of attention for social workers. Many children we work with are exposed to chronic stressors such as poverty, child maltreatment, and other forms of stressors and/or trauma. These experiences can be damaging to a child’s development, especially if they occur early in life, and the effects may be long-lasting. The first manuscript provides an overview of the human stress response and its potential deleterious effects on child brain development. It highlights specific brain regions affected by stress, and possible physical and mental health consequences of stress later in life.Building on …
"Living It In The Day To Day": Narratives Of Advanced Martial Artists, Michael Duncan Overton
"Living It In The Day To Day": Narratives Of Advanced Martial Artists, Michael Duncan Overton
Doctoral Dissertations
Western perspectives of learning often marginalize other-ways-of-knowing. A need to further understand other-ways-of-knowing, in particular non-Western perspectives, is a growing concern of the adult and continuing education field. Prior research supports the martial arts as a non-Western and other-way-of-knowing. However, the adult and continuing education field have underutilized the martial arts in research. The purpose of this narrative study was to explore adult learners’ lived experiences of learning and practicing martial arts in the southeastern United States of America. The two research questions that guided this study were “What experience(s) led adult learners to practice martial arts?” and “What are …
Philanthropic Influence On Public Education: A Study Of High-Leverage Venture Philanthropy Through Educational Investments Of Local Education Foundations In Tennessee, Joshua Adam Lowe
Doctoral Dissertations
More than $500 billion of funding went to public education in 2005 to support educational programming and instruction. At the same time, some of the most prominent, nationally-organized private foundations have sought to influence education by using high-leverage venture philanthropy grants. However, little research has been done to assess whether more local foundations have been following the lead of these national foundations with regards to increasing investments through high-leverage venture philanthropy to education. Being closer to local educational policy makers, the local foundations have great potential influence on local education.The purpose of this study is to analyze the philanthropic investments …
Nonlinear Control And Estimation Of An Infammatory Immune Response, Ouassim Bara
Nonlinear Control And Estimation Of An Infammatory Immune Response, Ouassim Bara
Doctoral Dissertations
The immune response is a complex mechanism that can be triggered by biological or physical stresses on the organism. However an excessive and dys-regulated inflammatory response may lead to sepsis, a critical state, promoting tissue damage, organ dysfunction or even death.The main objective in this dissertation is to derive a strategy consisting of manipulating pro and anti-inflammatory mediators in order to direct the state of a virtual patient to a healthy equilibrium, after some disturbance from health due to infection. Two key challenges need to be addressed in solving such a problem: estimating the unmeasurable states of the inflammatory model …
Novel Sustainable Anode Materials And Interfacial Chemistry For Improved Rechargeable Batteries, Yunchao Li
Novel Sustainable Anode Materials And Interfacial Chemistry For Improved Rechargeable Batteries, Yunchao Li
Doctoral Dissertations
The fast growth of the renewable energy market leads to a rapidly increased demand for high-performance energy storage. Despite the great success of the current lithium-ion batteries (LIBs) in portable electronics, the findings of new applications such as in electric vehicles and in large-scale energy storage revealed the limitations of current LIBs in terms of performance, cost, life time and safety. To meet the future application requirements, this dissertation is focused on the innovation and improvement of anode materials, characterization and understanding of material surface properties and modification of the anode materials.A new carbon material recovered from waste tire with …
Feasibility, And Resiliency, And Economic Impacts Of Energy Storage In Urban Water Systems: Case Study Of Cleveland, Tennessee, Susanna Hannah Sutherland
Feasibility, And Resiliency, And Economic Impacts Of Energy Storage In Urban Water Systems: Case Study Of Cleveland, Tennessee, Susanna Hannah Sutherland
Doctoral Dissertations
This research reduces the knowledge gap around how the water-energy nexus can be applied at the urban level, clarifying how a city water distribution system might be used to offset community energy consumption. The created methodology includes 3 research objectives. First, model scenarios are developed to determine opportunities for energy storage in urban water systems. Then, how increased energy storage capacity impacts water system resiliency is examined. Finally, the financial implications of scenarios are calculated.A closed-loop water system model (EPANET2) simulates Cleveland, Tennessee’s water distribution system, resolved to the neighborhood scale. Sectoral aggregated hourly energy use data provides a comparison …
Investigating Trends And Processes That Impact Tree Species Diversity Of Southern Forests At The Landscape Level, Andrew J. Hartsell
Investigating Trends And Processes That Impact Tree Species Diversity Of Southern Forests At The Landscape Level, Andrew J. Hartsell
Doctoral Dissertations
Global biodiversity is currently being threatened by multiple anthropogenic sources. The increase in genetically modified, artificially regenerated forests has raised concerns that this management scheme may be a source of species loss. This study investigates the impacts of urbanization, agricultural development, and southern yellow pine plantation establishment on tree species evenness, Shannon-Wiener index, and Simpson’s index of forest communities within the Gulf Coastal Plain of the southeastern United States. The impacts of varying spatial scale on possible predictors was investigated by utilizing nested watersheds from the Watershed Boundary Dataset (WBD). Techniques used in the analysis included Getis-Ord Gi* analysis, Local …
A Phenomenological Study Of Adolescent Pregnancy Loss, Jenny Stout Webb
A Phenomenological Study Of Adolescent Pregnancy Loss, Jenny Stout Webb
Doctoral Dissertations
Very little is known about the experience and long-term effects of pregnancy loss during adolescence. The purpose of this existential phenomenological research study was to gain a better understanding of the meanings adolescent mothers give to their experience of pregnancy loss. For this study, four participants were interviewed using unstructured, phenomenological interviews. The participants were 17 (3) and 18(1) at the time of the loss and ranged in age from 29 to 58 years at the time of the interviews. Data analysis resulted in the development of five themes to describe the experience of pregnancy loss during adolescence: 1) “It …
Optimal Allocation Of Dynamic Var Sources Addressing Fidvr Issues, Weihong Huang
Optimal Allocation Of Dynamic Var Sources Addressing Fidvr Issues, Weihong Huang
Doctoral Dissertations
Dynamic reactive power sources, also called dynamic var sources such as SVCs and STATCOMs; can effectively mitigate fault-induced delayed voltage recovery (FIDVR) and short-term voltage stability issues. Allocation of dynamic var sources has become an essential research topic. Currently, the allocation of dynamic var sources needs to address three problems, including the optimal placement, optimal sizes, and optimal settings of var sources, which are usually solved separately.Optimization of placement, sizing, and setting of dynamic var sources are complicated nonlinear optimization problems due to their non-convexity and the dependence of the constraints on time-series trajectories of post-fault responses. Thus, solving those …
Habitat And Population Assessments Of The Lake Sturgeon Acipenser Fulvescens Reintroduced To The Upper Tennessee River, Daniel James Walker
Habitat And Population Assessments Of The Lake Sturgeon Acipenser Fulvescens Reintroduced To The Upper Tennessee River, Daniel James Walker
Doctoral Dissertations
The Lake Sturgeon Acipenser fulvescens historically occurred throughout the United States and Canada. However, due to widespread overfishing and habitat loss it was extirpated from much of its range, especially in the lower latitudes. Since the year 2000, fisheries managers have been working to restore this species to the Tennessee and Cumberland Rivers where it has been extirpated since c. 1961. This reintroduction is comprised of annual releases of young-of-the-year Lake Sturgeon reared in head-start aquaculture facilities around the Southeastern U.S., and annual monitoring efforts that track the spread and growth of reintroduced individuals. In 2015, a management plan guiding …
Singled Out: Genomic Analysis Of Uncultured Microbes In Marine Sediments, Jordan Toby Bird
Singled Out: Genomic Analysis Of Uncultured Microbes In Marine Sediments, Jordan Toby Bird
Doctoral Dissertations
The vast majority of abundant taxa in marine sediment environments have not yielded to culture, leaving questions about their relationship to other taxa and their functional potential unanswered. However, in the absence of active cultures, careful application of various omics methods can be used to help us make useful inferences about their evolutionary history and how they have continued to survive in environments of extreme energy deprivation. For this dissertation, I have applied comparative genomics methods to members of two uncultured groups, the recently proposed Altiarchaeales order and a cosmopolitan taxon associated with the Actinobacteria phylum. Additionally, I combined transcript …
Discovering The Impact Of Diet, Genetic, And Sex Effects On Adipose, Skeletal Muscle, And Liver Metabolomes In Mice Using Untargeted Liquid-Chromatography Mass-Spectrometry, Ann Elizabeth Wells
Discovering The Impact Of Diet, Genetic, And Sex Effects On Adipose, Skeletal Muscle, And Liver Metabolomes In Mice Using Untargeted Liquid-Chromatography Mass-Spectrometry, Ann Elizabeth Wells
Doctoral Dissertations
The metabolome is the end product of all biochemical reactions in the body and is sensitive to external perturbations, such as diet, genetics, sex, disease, and environment. Understanding the dynamic relationship between metabolites and external inputs is key to delineating the metabolic underpinnings of disease. Mass-spectrometry based metabolomics provides a means through which the metabolome can be systemically and systematically profiled to discern alterations across thousands of metabolites at a time. The research in this dissertation characterized the effects of diet, genetics, and sex on the tissue metabolome. Adipose, skeletal muscle, and liver tissue were chosen due to their role …
A Framework For Reconciling Expert Opinions And Empirical Data For Hydropower Asset Management Decision-Making, Stephen Robert Signore
A Framework For Reconciling Expert Opinions And Empirical Data For Hydropower Asset Management Decision-Making, Stephen Robert Signore
Doctoral Dissertations
This research develops a framework for reconciling expert opinions of component lifetimes and empirical failure data to predict powertrain failure probabilities for Asset Management decision making purposes. Using probability models of component failures, fleetwide dispatch and component replacement history along with a large hydroelectric utility’s powertrain expert elicitation we propose a four use cases. The first use case enables a more detailed calculation of average component life. The second use case provides risk managers the ability to understand how dispatch affects the risk of a single component failure. The third and fourth use cases enables the recommendation of the distribution …
Noncontact Vital Signs Detection, Lingyun Ren
Noncontact Vital Signs Detection, Lingyun Ren
Doctoral Dissertations
Human health condition can be accessed by measurement of vital signs, i.e., respiratory rate (RR), heart rate (HR), blood oxygen level, temperature and blood pressure. Due to drawbacks of contact sensors in measurement, non-contact sensors such as imaging photoplethysmogram (IPPG) and Doppler radar system have been proposed for cardiorespiratory rates detection by researchers.The UWB pulse Doppler radars provide high resolution range-time-frequency information. It is bestowed with advantages of low transmitted power, through-wall capabilities, and high resolution in localization. However, the poor signal to noise ratio (SNR) makes it challenging for UWB radar systems to accurately detect the heartbeat of a …
Evaluation Of Inveon Pre-Clinical Positron Emission Tomography (Pet) Scanner Geant4 Application For Tomographic Imaging (Gate) Model For Multi-Positron Emission Particle Tracking (M-Pept), Roque Antonio Santos Torres
Evaluation Of Inveon Pre-Clinical Positron Emission Tomography (Pet) Scanner Geant4 Application For Tomographic Imaging (Gate) Model For Multi-Positron Emission Particle Tracking (M-Pept), Roque Antonio Santos Torres
Doctoral Dissertations
A Sodium-22 point source of activity 10 μCi [microcurie] is moved through an Inveon Pre-Clinical Positron Emission Tomography (PET) scanner, and the scan data are sent to Multi-Positron Emission Particle Tracking (M-PEPT) software to recreate the particle track. A Geant4 Application for Tomographic Imaging (GATE) model of the Inveon is used to simulate the scanner response to point source movements identical to those prescribed in experiments. Simulated and physical experiment outcomes are compared to qualify the GATE model for the M-PEPT application. GATE over predicts the number of detected coincident lines (CL). The standard deviation of particle positions predicted by …
Hungaria Asteroid Region Telescopic Spectral Survey (Hartss): Establishing Asteroid-Meteorite Connections Between Hungaria Asteroids And Meteorites Of The Acapulcoite-Lodranite Clan, Michael Peter Lucas
Hungaria Asteroid Region Telescopic Spectral Survey (Hartss): Establishing Asteroid-Meteorite Connections Between Hungaria Asteroids And Meteorites Of The Acapulcoite-Lodranite Clan, Michael Peter Lucas
Doctoral Dissertations
Hungaria region asteroids are survivors of giant planet migration that destabilized a now extinct inner-portion of the primordial asteroid belt. In this scenario, the Hungaria region represents a “purgatory” for the closest, preserved samples of material from which the terrestrial planets accreted. Deciphering the surface composition of these samples may provide constraints on the nature of the primordial building blocks of the terrestrial planets. We carried out a two-phased ground-based observational campaign—Hungaria Asteroid Region Telescopic Spectral Survey (HARTSS)—to record their visible and near-infrared reflectance spectra. We analyzed these spectra to characterize the taxonomy, surface mineralogy, and potential meteorite analogs of …
Almost Symmetries And The Unit Commitment Problem, Bernard Albert Knueven
Almost Symmetries And The Unit Commitment Problem, Bernard Albert Knueven
Doctoral Dissertations
This thesis explores two main topics. The first is almost symmetry detection on graphs. The presence of symmetry in combinatorial optimization problems has long been considered an anathema, but in the past decade considerable progress has been made. Modern integer and constraint programming solvers have automatic symmetry detection built-in to either exploit or avoid symmetric regions of the search space. Automatic symmetry detection generally works by converting the input problem to a graph which is in exact correspondence with the problem formulation. Symmetry can then be detected on this graph using one of the excellent existing algorithms; these are also …
Prediction Of Host-Microbe Interactions From Community High-Throughput Sequencing Data, Joshua Michael Stough
Prediction Of Host-Microbe Interactions From Community High-Throughput Sequencing Data, Joshua Michael Stough
Doctoral Dissertations
Microbial ecology is a diverse field, with a broad range of taxa, habitats, and trophic structures studied. Many of the major areas of research were developed independently, each with their own unique methods and standards, and their own questions and focus. This has changed in recent decades with the widespread implementation of culture-independent techniques, which exploit mechanisms shared by all life, regardless of habitat. In particular, high-throughput sequencing of environmentally isolated DNA and RNA has done much to expand our knowledge of the planet’s microbial diversity and has allowed us to explore the complex interplay between community members. Additionally, metatranscriptomic …
Development Of A Biaxial Stretch Bioreactor And Finite Element Models For Mechanobiological Study Of Aortic Valve Leaflets, Ying Lei
Doctoral Dissertations
Aortic heart valve disease is a significant cause of mortality worldwide; and replacement surgery is necessary in 70% of cases. Tissue engineered heart valves (TEHVs) are biocompatible and biodegradable, with ability to grow with the patient. However, to date, TEHVs mostly lack ability to withstand native mechanical forces since they are unable to mimic the heterogeneous and anisotropic structure of extracellular matrix (ECM) in native valves. Cyclic stretch is known to modulate ECM fiber synthesis and alignment. However, little tools are available for studying the interaction between aortic tissues and stretch condition. Finite element method is a powerful tool to …
The Effectiveness Of Mixed Reality-Based Intervention For Children With Autism Spectrum Disorders: A Meta-Analysis And Single-Case Study, Byungkeon Kim
Doctoral Dissertations
The development of technology has led to the development of various software and application as well as computer-based devices, and is extending its influence even to the mixed reality domain. These technologies are being used actively in the education field for students without disabilities as well as for students with disabilities. In recent years, the instructional application of technology has been accelerated by the development and dissemination of hand-held smart devices. These technologies are increasingly promoting the participation of students with ASD in education and rehabilitation programs. Currently, the number of apps developed as interventions for students with ASD is …
Functional Characterization Of Integrated Chemotaxis Pathways And Proteins In The Soil Bacterium, Azospirillum Brasilense, Jessica Marie Gullett
Functional Characterization Of Integrated Chemotaxis Pathways And Proteins In The Soil Bacterium, Azospirillum Brasilense, Jessica Marie Gullett
Doctoral Dissertations
Chemotaxis is the biased movement of cells in a chemical gradient. Most of what we know about chemotaxis comes from work in Escherichia coli, which encodes one chemotaxis signaling pathway. However, recent genome sequencing provided evidence that most chemotactic bacteria encode for more than one chemotaxis signaling pathway, but little is known about how these multiple pathways function. In the soil bacterium, Azospirillum brasilense, two chemotaxis pathways are used to control motility in response to chemicals. We aim to characterize these pathways and determine whether or not interaction exists between proteins of the two pathways. We find that …
The Separation Of Bismuth-213 From Actinium-225 And The Ion Exchange Properties Of The Alkali Metal Cations With An Inorganic Resin, Mark Alan Moore
The Separation Of Bismuth-213 From Actinium-225 And The Ion Exchange Properties Of The Alkali Metal Cations With An Inorganic Resin, Mark Alan Moore
Doctoral Dissertations
Interest in the use of alpha radiation emitters in radio immunotherapy is due to the high linear energy transfer and short range of alpha radiation. These properties enable the targeting of single tumor cells with diminished risk of damaging the surrounding tissue. Significant research has been done in the separation of the alpha emitter Bismuth-213 from its parent solution of Actinium-225 using organic resins. Due to radiolytic damage to the resin emphasis in the research has focused on the rapid elution of Bismuth-213 or storage of the parent Actinium-225 solution on a more robust resin. Inorganic ion exchange resins have …
Exploring Grades 3-8 Principals' Beliefs About The New Tnready Standards: An Assets Or Deficits Perspective?, Mary Elizabeth Blevins
Exploring Grades 3-8 Principals' Beliefs About The New Tnready Standards: An Assets Or Deficits Perspective?, Mary Elizabeth Blevins
Doctoral Dissertations
Porumbu (2015) proposed that belief systems are important because they influence behavior. For example, a principal's belief system could determine how teaching strategies are monitored, how support for struggling students are accessed, and how alternative support and interventions for those students are implemented. As part of cultural capital, both acknowledging and valuing others' knowledge and skills reflect an asset perspective (Fox, 2016); in contrast is the deficit perspective. Massey, Charles, Lundy, and Fischer (2003) found that the deficit perspective is often found in education systems’ explanation of poor performance.The purpose of this quantitative study was to explore principals' responses regarding …
The Biochemical Characterization Of The Phosphatidylserine Synthase From Candida Albicans As A Drug Target, Chelsi Danielle Cassilly
The Biochemical Characterization Of The Phosphatidylserine Synthase From Candida Albicans As A Drug Target, Chelsi Danielle Cassilly
Doctoral Dissertations
Treatments for Candida albicans systemic infections are limited to three classes of antifungals, some of which have harmful side effects or increasing instances of antifungal resistance. These shortcomings illustrate a need for new antifungals. The phosphatidylserine (PS) synthase, Cho1p, represents a potential drug target that can address this need. Cho1p is involved in a major phospholipid biosynthesis pathway and represents a novel drug target for three key reasons: 1) It is required for virulence, indicating that inhibitors of Cho1p would render the organism incapable of causing infection; 2) it is absent in mammals, so inhibitors potentially have no toxic side …
Nonlinear Oscillation Analysis And Modal Decoupling For Power Systems, Bin Wang
Nonlinear Oscillation Analysis And Modal Decoupling For Power Systems, Bin Wang
Doctoral Dissertations
This work analyzes power system nonlinear electromechanical oscillations (EOs). Two new tools are proposed for understanding better nonlinear oscillations and for angular stability analysis of power systems. The proposed tools and methodology can also be extended and applied to general high dimensional nonlinear dynamical systems besides power systems.The analysis of the nonlinear EOs on a single-machine-infinite-bus (SMIB) power system is first presented and a new tool called Frequency-Amplitude (F-A) curve is proposed. The F-A curve shows that the oscillation frequency (OF) decreases from the natural frequency toward zero when the oscillation amplitude (OA) grows to some critical threshold. It is …
Social Work Practice In Public Defense, Sarah Beck Buchanan
Social Work Practice In Public Defense, Sarah Beck Buchanan
Doctoral Dissertations
Little is known about the collaboration between public defense and social work despite the growing implementation of the approach. This dissertation attempts to better understand the implications for social work practice in the public defense setting by 1) reviewing the literature to gain an understanding of social work roles, services, and practice outcomes, 2) examining demographic characteristics and criminal charges incurred by a group of clients in a public defense setting to better understand the population to develop and tailor interventions, and 3) determining the effect of social work services in terms of the number and severity of criminal charges …
Electromechanical Dynamics Of High Photovoltaic Power Grids, Shutang You
Electromechanical Dynamics Of High Photovoltaic Power Grids, Shutang You
Doctoral Dissertations
This dissertation study focuses on the impact of high PV penetration on power grid electromechanical dynamics. Several major aspects of power grid electromechanical dynamics are studied under high PV penetration, including frequency response and control, inter-area oscillations, transient rotor angle stability and electromechanical wave propagation.To obtain dynamic models that can reasonably represent future power systems, Chapter One studies the co-optimization of generation and transmission with large-scale wind and solar. The stochastic nature of renewables is considered in the formulation of mixed-integer programming model. Chapter Two presents the development procedures of high PV model and investigates the impact of high PV …