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Do Both Misery And Happiness Love Company? The Emotional Consequences Of Listening To Experiences Shared By Others., Samantha Warchol Dec 2014

Do Both Misery And Happiness Love Company? The Emotional Consequences Of Listening To Experiences Shared By Others., Samantha Warchol

Chancellor’s Honors Program Projects

No abstract provided.


Bidirectional Associations Between Parenting Behavior And Child Callous-Unemotional Traits: Do Delinquent Peer Affiliations And/Or Parental Psychopathology Moderate These Links?, Amber Rochelle Wimsatt Dec 2014

Bidirectional Associations Between Parenting Behavior And Child Callous-Unemotional Traits: Do Delinquent Peer Affiliations And/Or Parental Psychopathology Moderate These Links?, Amber Rochelle Wimsatt

Doctoral Dissertations

The current study examined bidirectional associations between callous-unemotional (CU) traits and parenting dimensions and evaluated whether these associations changed as children aged. Furthermore, this study extended the literature by examining whether these relations were moderated by delinquent peer affiliation and/or parental depression. Proposed relations were examined using a longitudinal sample of 120 aggressive boys (59.6%) and girls (40.4%) who were in the 4th grade (M = 10.56 years, SD = .56) at baseline and were followed over four years. A series of generalized estimating equation [GEE] models revealed reciprocal relations between CU traits and corporal punishment. Consistent with …


Stress And Resilience: The Negative And Positive Aspects Of Being An Asian American Lesbian Or Bisexual Woman, Mi Ra Sung Dec 2014

Stress And Resilience: The Negative And Positive Aspects Of Being An Asian American Lesbian Or Bisexual Woman, Mi Ra Sung

Doctoral Dissertations

Despite the richness of the literature about minority stress and negative psychological outcomes and growing attention on lesbian, gay, bisexual (LGB) people of color, few studies have examined the intersection of multiple identities of Asian American lesbian and bisexual women (AA LBW). Thus, the purpose of this study was to provide an understanding of the experiences of 50 AA LBW. More specifically, this study explored challenges, coping strategies, and positive aspects of being an AA LBW through the lens of intersectionality. Qualitative analyses revealed three overarching domains concerning day-to-day challenges faced by AA LBW: living as AA sexual minority women …


Client Attachment As A Predictor Of Therapy Outcome And Premature Termination, Gahee Choi Dec 2014

Client Attachment As A Predictor Of Therapy Outcome And Premature Termination, Gahee Choi

Doctoral Dissertations

The primary purpose of this study was to examine how clients’ self-reported adult attachment pattern and their attachment to the counselor are associated with working alliance and premature termination. A total of 65 clients at a large southeastern university counseling center were included in data analysis. Clients in this study completed survey packets including the Experiences in Close Relationships Scale (Brennan, Clark, & Shaver, 1998), the Working Alliance Inventory (Horvath & Greenberg, 1989), the Client Attachment to Therapist Scale (Mallinckrodt, Gantt, & Coble, 1995), the Outcome Questionnaire 45 and 30 items (Lambert et al. 1996), and the Therapeutic Distance Inventory …


Relationships Among Depression, Posttraumatic Stress Disorder, Forgiveness, Meaning In Life, And Spirituality In Survivors Of Intimate Partner Violence, Shannon Marie Rogers Dec 2014

Relationships Among Depression, Posttraumatic Stress Disorder, Forgiveness, Meaning In Life, And Spirituality In Survivors Of Intimate Partner Violence, Shannon Marie Rogers

Doctoral Dissertations

One hundred twenty nine survivors of interpersonal violence completed a paper-and-pencil survey to evaluate depression, PTSD, forgiveness, meaning in life, and spirituality. Five self-report measures were completed including: the Center for Epidemiological Studies-Depression scale, the PTSD Checklist – Stressor Specific version, the Transgression-Related Interpersonal Motivations Inventory, and the Spiritual Involvement and Beliefs Scale. The majority of the participants were female and Caucasian. Significant correlations were found between PTSD and presence of meaning, as well as depression and both presence of and search for meaning. However, hierarchical multiple regressions results indicated that depression and the two meaning in life subscales contributed …


Assessing Motives For Consensual Sex: Development Of The Sexual Motives Questionnaire, Vanessa Tirone Dec 2014

Assessing Motives For Consensual Sex: Development Of The Sexual Motives Questionnaire, Vanessa Tirone

Doctoral Dissertations

The present study describes the development and preliminary validation of the Sexual Motives Questionnaire (SMQ), a measure of motives for consensual sex. The measure is informed two dispositional theories, functional theory and self-construal theories, which suggest that individuals are motivated to engage in behavior due to approach/avoidance and independent/interdependent tendencies, respectively. Items were also selected to reflect sexual scripts and fear of sexual and physical violence. A total of 81 items was administered to 920 undergraduates. Exploratory factor analysis was conducted utilizing the 821 participants with complete data. The final sample was predominately heterosexual (96%) and Caucasian (83%) with a …


Testing Claims Of Efficacy And Mechanism Of Action For Emotion Focused Couples Therapy: A Dyadic Case Study Using Time-Series Design, Albert Jun-Wei Wong Dec 2014

Testing Claims Of Efficacy And Mechanism Of Action For Emotion Focused Couples Therapy: A Dyadic Case Study Using Time-Series Design, Albert Jun-Wei Wong

Doctoral Dissertations

The overall purpose of this study was to test claims regarding both the efficacy and mechanism of change for Emotion Focused Couple Therapy (EFT). Although a number of treatment outcome studies have been conducted on EFT, the vast majority of these studies emanate from the research laboratories associated with the two founders of EFT. Additionally, most EFT research has examined treatment outcome rather than mechanisms of change. This study used a time-series single-case experimental design approach to examine both the efficacy and the mechanisms of change in EFT for couple distress. I systematically tracked the symptoms of couple distress across …


Assessing The Genetic Diversity Of The Genus Viburnum Using Simple Sequence Repeats, Deborah Dean Dec 2014

Assessing The Genetic Diversity Of The Genus Viburnum Using Simple Sequence Repeats, Deborah Dean

Doctoral Dissertations

The genus Viburnum was established in 1753 by Linnaeus and is the largest genus in the Adoxaceae and consists of approximately 160 species. Viburnum species are small trees which grow throughout the temperate regions of the Northern Hemisphere (Hoch, 1995). While this genus shares little variety in fruit and flower morphology, it is diverse in many other traits. As molecular studies advance, this large genus continues to undergo reclassification. Here three SSR libraries were constructed to discern additional molecular insight into this vast genus.

Microsatellite markers were developed to characterize Viburnum on several different levels. V. dilatatum is an introduced …


Reverse Genetics Approach To Examine Myosin Xi Functions In Pollen Tube Growth, Stephanie Lin Madison Dec 2014

Reverse Genetics Approach To Examine Myosin Xi Functions In Pollen Tube Growth, Stephanie Lin Madison

Doctoral Dissertations

Pollen tube growth is an essential aspect of plant reproduction because it is the mechanism through which non-motile sperm cells are delivered to ovules thus allowing fertilization to occur. A pollen tube is a single cell that only grows at the tip, and this tip growth depends on actin filaments. Plants encode class VIII and class XI myosins as actin-based motor proteins, of which class XI myosins are required for cell expansion in vegetative tissues.

In Arabidopsis thaliana, 6 of 13 myosin XI genes are expressed in pollen: XIA, XIB, XIC, XID, XIE, and …


Planning For Communication Through Rehearsal Imagined Interactions, Martijn Jos Van Kelegom Dec 2014

Planning For Communication Through Rehearsal Imagined Interactions, Martijn Jos Van Kelegom

Doctoral Dissertations

Imagined interactions are mental representations of conversations with significant others. One function they may serve is as a rehearsal for an anticipated encounter. The process by which this rehearsal occurs is investigated using Dillard’s (1990) Goals-Plans-Action model and Berger’s (1997) Planning Theory of Communication. A causal model is proposed for the relationships between domain knowledge, use of retroactive imagined interactions, specificity, and discrepancy of the proactive imagined interaction. This model is tested using survey data (N = 210), and additional data were collected assessing characteristics of the anticipated conversations. Results and additional analyses suggest that rehearsal occurs in many …


Interactive Feature Selection And Visualization For Large Observational Data, Jingyuan Wang Dec 2014

Interactive Feature Selection And Visualization For Large Observational Data, Jingyuan Wang

Doctoral Dissertations

Data can create enormous values in both scientific and industrial fields, especially for access to new knowledge and inspiration of innovation. As the massive increases in computing power, data storage capacity, as well as capability of data generation and collection, the scientific research communities are confronting with a transformation of exploiting the advanced uses of the large-scale, complex, and high-resolution data sets in situation awareness and decision-making projects. To comprehensively analyze the big data problems requires the analyses aiming at various aspects which involves of effective selections of static and time-varying feature patterns that fulfills the interests of domain users. …


Long-Term Impacts Of Tillage, Cover Crops, And Nitrogen Rates On Microbial Community Dynamics And Soil Quality Parameters Under Continuous Cotton Production In West Tennessee, Lilian Wanjiru Mbuthia Dec 2014

Long-Term Impacts Of Tillage, Cover Crops, And Nitrogen Rates On Microbial Community Dynamics And Soil Quality Parameters Under Continuous Cotton Production In West Tennessee, Lilian Wanjiru Mbuthia

Doctoral Dissertations

Microbial communities play a central role in nutrient cycling and soil quality in agro-ecosystems. This research focused on a comparative analysis of the microbial community structure and activity of soils on long-term (31 years) continuous cotton- Gossypium hirsutum L., production in West Tennessee under conservation agricultural (CA) and conventional tillage practices that included: Nitrogen (N) fertilizer rates (N-rates) (0, 34, 67 and 101 kg N per ha); Cover crops (Hairy vetch-Vicia villosa and winter wheat- Triticum aestivum, and a No Cover control); and Tillage (Till and No-till). It was expected that microbial diversity, activity and soil quality would be …


The Dissolution Of Cellulose In Ionic Liquids - A Molecular Dynamics Study, Barmak Mostofian Dec 2014

The Dissolution Of Cellulose In Ionic Liquids - A Molecular Dynamics Study, Barmak Mostofian

Doctoral Dissertations

The use of ionic liquids for the dissolution of cellulose promises an alternative method for the thermochemical pretreatment of biomass that may be more efficient and environmentally acceptable than conventional techniques in aqueous solution. Understanding how ionic liquids act on cellulose is essential for improving pretreatment conditions and thus detailed knowledge of the interactions between solute and solvent molecules is necessary. Here, results from the first all-atom molecular dynamics simulation of an entire cellulose microfibril in 1-butyl-3-methylimidazolium chloride (BmimCl) are presented and the interactions and orientations of solvent ions with respect to glucose units on the hydrophobic and hydrophilic surfaces …


Pore Selectivity And Gating Of Arabidopsis Nodulin 26 Intrinsic Proteins And Roles In Boric Acid Transport In Reproductive Growth, Tian Li Dec 2014

Pore Selectivity And Gating Of Arabidopsis Nodulin 26 Intrinsic Proteins And Roles In Boric Acid Transport In Reproductive Growth, Tian Li

Doctoral Dissertations

Plant nodulin-26 intrinsic proteins (NIPs) are members of the aquaporin superfamily that serve as multifunctional channels of uncharged metabolites and water. They share the same canonical hourglass fold as the aquaporin family. The aromatic arginine (ar/R) selectivity filter controls transport selectivity based on size, hydrophobicity, and hydrogen bonding with substrates. In Arabidopsis thaliana, NIP II subclass proteins contain a conserved ar/R “pore signature” that is composed of Alanine at the helix 2 position (H2), Valine/Isoleucine at the helix 5 position (H5), and an Alanine (LE1) and an invariant Arginine (LE2) at the two loop E positions. In this study, …


The Relationship Between Hope And Self-Directed Learning In The Workplace, Vicki Martin Dieffenderfer Dec 2014

The Relationship Between Hope And Self-Directed Learning In The Workplace, Vicki Martin Dieffenderfer

Doctoral Dissertations

This study investigated the relationship between self-directed learning and hope in the workplace. Participants completed two self-directed learning instruments, the Survey of Adult Learning Traits (SALT) (Hogg, 2008) and the Learner Self-directedness in the Workplace Scale (LSWS) (De Bruin & De Bruin, 2011), along with two hope scales, the Hope Trait Scale (Snyder et al., 1991) and the author-generated Workplace Learning Hope Scale. Correlation, ANOVA, and multiple regressions were used to test the relationship and differences between self-directed learning and hope, specifically within the domain of workplace learning. All instruments utilized in this study displayed sound internal consistency reliability. The …


Computer Simulations Of Enzymes, Jianzhuang Yao Dec 2014

Computer Simulations Of Enzymes, Jianzhuang Yao

Doctoral Dissertations

Enzymes are important catalysts in living systems, and understanding catalytic mechanisms of enzymes is an important task for modern biophysics and biochemistry. Computer simulations have emerged as very useful tools for understanding how enzymes work. In this dissertation, QM/MM MD simulations were applied to study the catalytic mechanisms of several enzymes, including sedolisin, S-adenosyl-L-methionine (AdoMet)-dependent methyltransferases, and salicylic acid binding protein 2. For sedolisin, we focus on the acylation and deacylation reactions catalyzed by the enzymes. We proposed a general acid/base mechanism involving the Glu/Asp residues at the active site. MD and QM/MM free energy simulations on pro-kumamolisin show that …


Behavior Of Larger-Diameter Strands In The Disturbed Region Of Prestressed Concrete Girders, John Verlin Cabage Jr. Dec 2014

Behavior Of Larger-Diameter Strands In The Disturbed Region Of Prestressed Concrete Girders, John Verlin Cabage Jr.

Doctoral Dissertations

Traditionally, the Tennessee Department of Transportation has been using American Association of State Highway and Transportation Officials – Prestressed/Precast Concrete Institute Bulb Tee (AASHTO-PCI BT) sections for its prestressed concrete bridges. These sections have limited bottom flange widths where the prestressing strands are located. To increase span capacities of these sections, other States have adopted new sections with a wider flange width. Producers in Tennessee have raised concerns about the cost of the new steel forms to accommodate these new sections. As an alternative, this research examines the use of larger diameter strand in conjunction with high-strength concrete and standard …


Enhancement Of Chronically-Induced Breast Carcinogenesis By Combined Environmental And Dietary Carcinogens And Suppression By Dietary Agents, Lenora A. Pluchino Dec 2014

Enhancement Of Chronically-Induced Breast Carcinogenesis By Combined Environmental And Dietary Carcinogens And Suppression By Dietary Agents, Lenora A. Pluchino

Doctoral Dissertations

Most breast cancers occur sporadically due to long-term exposure to low-dose carcinogens present in our environment and diet. American lifestyles involve frequent exposures to smoke, polluted air, and high temperature-cooked meats comprising multiple carcinogens, such as 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK), benzo[α[alpha]]pyrene (B[α[alpha]]P), and 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP). To investigate whether these carcinogens may act together to enhance breast cell carcinogenesis, we used our chronically-induced breast cell carcinogenesis model wherein we repeatedly expose non-cancerous human breast epithelial MCF10A cells to physiologically-achievable doses of carcinogens to progressively induce cellular acquisition of cancer-associated properties including reduced dependence on growth factors, anchorage-independent growth, increased cell proliferation, migration and …


From Foraging To Food Production On The Southern Cumberland Plateau Of Alabama And Tennessee, U.S.A., Stephen Byrnes Carmody Dec 2014

From Foraging To Food Production On The Southern Cumberland Plateau Of Alabama And Tennessee, U.S.A., Stephen Byrnes Carmody

Doctoral Dissertations

Research involving the origin of plant domestication remains as important today as ever. While early anthropologists viewed plant domestication as a necessary precondition for cultural development, more recent ethnographic studies have shown that agriculture was a much more labor intensive subsistence practice than hunting and gathering, leading many to question the reasons behind the prehistoric transition. Today, research and advances in technology have provided conclusive evidence to include the Eastern Woodlands of North America as one of the eight global centers of indigenous plant domestication. Although the timing of domestication and the plants involved in early horticultural systems are well …


Calcium And Leucine Modulation Of Airway Inflammation, Patricia Louise Brown Dec 2014

Calcium And Leucine Modulation Of Airway Inflammation, Patricia Louise Brown

Doctoral Dissertations

Over the past several decades the prevalence of obesity and asthma have increased in a parallel fashion. Recent studies reported a positive relationship between the two disorders that may in fact be causal. Although the link between obesity and asthma has become widely recognized, the underlying pathophysiological connection is not elucidated. Increased markers of inflammatory and oxidative stress are present in obesity and asthma suggesting the link is immunological. The systemic inflammation observed in obesity may potentially initiate adverse affects in the airways. Previous studies have shown that consumption of dairy foods (rich in calcium and leucine) suppress 1,25-dihydroxycholecalciferol (calcitriol) …


Absorption And Utilization Of Choline And Vitamin B12 In Lactating Dairy Cows Using Different Delivery Methods, Virginia Maria Artegoitia Etcheverry Dec 2014

Absorption And Utilization Of Choline And Vitamin B12 In Lactating Dairy Cows Using Different Delivery Methods, Virginia Maria Artegoitia Etcheverry

Doctoral Dissertations

Choline and vitamin B12 are essential nutrients for growth and performances of production animals. However, both nutrients are extensively degraded during digestion in the rumen. This thesis comprised three experiments. First, four cows equipped with a rumen cannula and catheters in the portal vein and a mesenteric artery received a post-ruminal bolus of: 1) cyanocobalamin (CN-CBL) alone (0.1 g) [gram], 2) CN-CBL (0.1 g) + casein (10 g) or 3) CN-CBL (0.1 g) + whey proteins (10 g). After the bolus, blood samples were taken until 24 h [hour] post-bolus. The intestinal absorption of CN-CBL was greater when the vitamin …


Supramolecular Association Of Hydrogen-Bonded Polybutadienes Functionalized With Ureidopyrimidone, Sachin Laxman Bobade Dec 2014

Supramolecular Association Of Hydrogen-Bonded Polybutadienes Functionalized With Ureidopyrimidone, Sachin Laxman Bobade

Doctoral Dissertations

Ureidopyrimidone (UPy) is a well-known self-complementary quadruple hydrogen bonding unit, extensively applied in the preparation of supramolecular polymers with enhanced physical properties. The property enhancement is assigned partly to linear chain extension and fibrillar nanophase separation due to secondary hydrogen bonding by urethane and urea linker, though a clear distinctive structure property relationship has not be reported. In this work, two distinct sets of UPy functional polymers, a series of monochelic polybutadienes (PBd) and telechelic polybutadienes, were synthesized and analyzed by solution and bulk characterization techniques to probe the role of polymer chain mobility and polarity on the UPy chain-end …


Photosystem I-Based Applications For The Photo-Catalyzed Production Of Hydrogen And Electricity, Rosemary Khuu Le Dec 2014

Photosystem I-Based Applications For The Photo-Catalyzed Production Of Hydrogen And Electricity, Rosemary Khuu Le

Doctoral Dissertations

The aim of this dissertation was to optimize systems integrating the photosystem I (PSI) redox protein, which is involved in photosynthesis, with noble metals for electron transfer to show its versatility: 1) in solution coupled with platinum to mediate hydrogen evolution and 2) on a planar gold surface for electricity production.

Response surface methodology was utilized to study variables that affect hydrogen (H2) yield from platinized-PSI. Light intensity, temperature, and platinum concentration were varied during the platinum-photo-reduction process. Analysis of the effects of the variables on H2 yield allowed for determination of a condition for optimized hydrogen …


The Green Staff Of Asclepius: Envisioning Sustainable Medicine, Jason Lee Fishel Dec 2014

The Green Staff Of Asclepius: Envisioning Sustainable Medicine, Jason Lee Fishel

Doctoral Dissertations

To make society sustainable our institutions must also become sustainable. As an institution, health care contributes to environmental degradation. While unsurprising, contributions to environmental degradation increase risk factors for disease and illness, effectively frustrating the goals of medicine. To find ways to make health care sustainable I begin by reviewing the literature on sustainability from within environmental ethics and two previous attempts at envisioning sustainable health care in order to learn what to include in a vision of sustainable health care. Then I examine problems specific to making medicine sustainable by investigating how sustainability might affect the principles of medicine. …


Scattering Amplitudes In Flat Space And Anti-De Sitter Space, Savan Kharel Dec 2014

Scattering Amplitudes In Flat Space And Anti-De Sitter Space, Savan Kharel

Doctoral Dissertations

We calculate gauge theory one-loop amplitudes with the aid of the complex shift used in the Britto- Cachazo-Feng-Witten (BCFW) recursion relations of tree amplitudes. We apply the shift to the integrand and show that the contribution from the limit of infinite shift vanishes after integrating over the loop momentum, with a judicious choice of basis for polarization vectors. This enables us to write the one-loop amplitude in terms of on-shell tree and lower-point one-loop amplitudes. Some of the tree amplitudes are forward amplitudes. We show that their potential singularities do not contribute and the BCFW recursion relations can be applied …


Flatness-Based Control Methodologies To Improve Frequency Regulation In Power Systems With High Penetration Of Wind, Maryam Hassani Variani Dec 2014

Flatness-Based Control Methodologies To Improve Frequency Regulation In Power Systems With High Penetration Of Wind, Maryam Hassani Variani

Doctoral Dissertations

To allow for high penetration of distributed generation and alternative energy units, it is critical to minimize the complexity of generator controls and to minimize the need for close coordination across regions. We propose that existing controls be replaced by a two-tier structure of local control operating within a global context of situational awareness. Flatness as an extension of controllability for non-linear systems is a key to enabling planning and optimization at various levels of the grid in this structure. In this study, flatness-based control for: one, Automatic Generation Control (AGC) of a multi-machine system including conventional generators; and two, …


Characterizing The Mechanical Behavior Of Single And Polycrystalline Silicon Carbide Using Nanoindentation., Amit Datye Dec 2014

Characterizing The Mechanical Behavior Of Single And Polycrystalline Silicon Carbide Using Nanoindentation., Amit Datye

Doctoral Dissertations

This research aims at enhancing the fundamental understanding of mechanisms controlling the deformation and fracture of silicon carbide based ceramics (single- and poly-crystal). The role of microstructure and material properties on the energy absorption capability of SiC is studied. This research helps to improve the ability to quantitatively predict the initiation and propagation of fracture and the interaction between fracture and plasticity, which provides a step towards a mechanistic understanding of deformation and failure properties of ceramic single crystals and polycrystals. The validity of the indentation-cracking method for toughness measurement is examined using nanoindentation tests with different indenters (spherical, pyramidal). …


Social Fingerprinting: Identifying Users Of Social Networks By Their Data Footprint, Denise Koessler Gosnell Dec 2014

Social Fingerprinting: Identifying Users Of Social Networks By Their Data Footprint, Denise Koessler Gosnell

Doctoral Dissertations

This research defines, models, and quantifies a new metric for social networks: the social fingerprint. Just as one's fingers leave behind a unique trace in a print, this dissertation introduces and demonstrates that the manner in which people interact with other accounts on social networks creates a unique data trail. Accurate identification of a user's social fingerprint can address the growing demand for improved techniques in unique user account analysis, computational forensics and social network analysis.

In this dissertation, we theorize, construct and test novel software and methodologies which quantify features of social network data. All approaches and methodologies are …


Going Gothic: Spanish Unity And Blame In The Legend Of Rodrigo And Florinda, Sara A. Gottardi Dec 2014

Going Gothic: Spanish Unity And Blame In The Legend Of Rodrigo And Florinda, Sara A. Gottardi

Doctoral Dissertations

The Legend of Rodrigo and Florinda is used to explain the causes for the successful Muslim invasion of Spain. My dissertation discusses six medieval versions of this legend, three Muslim and three Christian. I trace variations in blame to identify the different strata of society that are described as the corrosive catalysts for the Visigoths' divine punishment. I also analyze each source's presentation of the Visigothic prior to the invasion and examine how they assess the fracture of Spain into smaller kingdoms after the invasion. Identifying the Muslim invasion as a form of divine chastisement inherently includes the idea that …


Effect Of Small Interfering Rnas On In Vitro Replication And Gene Expression Of Feline Coronavirus, Eman Ahmed Mohamed Anis Dec 2014

Effect Of Small Interfering Rnas On In Vitro Replication And Gene Expression Of Feline Coronavirus, Eman Ahmed Mohamed Anis

Doctoral Dissertations

Feline corononavirus (FCoV) infection is ubiquitous in domestic cat populations worldwide and is usually associated with subclinical or mild enteritis. However, in some cats infection may result in the development of a fatal progressive disease called feline infectious peritonitis (FIP). FIP is considered to be the major cause of infectious-related death in pet cats. Currently, there is no protective vaccine or curative treatment to this highly fatal disease. In this study, we evaluated the ability of small interfering RNAs (siRNAs) to inhibit the in vitro viral replication and gene expression of FCoV as a potential treatment for FIP.

Five synthetic …