Digital Commons Network^™

Feline Lentivirus: Molecular Analysis And Epidemiology In Southern African Lions, Hayley Rebecca Adams

Doctoral Dissertations

Feline immunodeficiency virus is a retrovirus of domestic cats causing significant lifelong infection. Infection has also been detected in nondomestic species, including African lions. It is endemic in certain populations in east and southern Africa. Infection leads to immunologic dysfunction and immunosuppressive disease in domestic cats; however, little research exists about the pathogenic effects of infection in lions and its epidemiological impact on free-ranging and captive populations. Little is known about the lentivirus in these populations at the molecular and host level. Analysis of the virus from these populations is necessary for development of detection assays that are both sensitive …

Arsenic Phytoremediation: Engineering Of An Arsenic-Specific Phytosensor And Molecular Insights Of Arsenate Metabolism Through Investigations Of Arabidopsis Thaliana, Pteris Cretica, And Pteris Vittata, Jason Miles Abercrombie

Doctoral Dissertations

This dissertation is a compilation of four studies that were conducted in the laboratory of Dr. C. Neal Stewart, Jr. at the University of Tennessee, Knoxville. The first study describes an investigation into arsenate metabolism in Arabidopsis thaliana using microarray technology. The second study summarizes progress made to date towards the development of an As-specific phytosensor, or a plant genetically engineered to detect the presence of As in the environment. The third study describes efforts towards genetic transformation of Pteris cretica and Pteris vittata, both As-hyperaccumulating ferns that have been recently demonstrated as effective in the removal of As …

Improving Scalability And Usability Of Parallel Runtime Environments For High Availability And High Performance Systems, Thara Angskun

Doctoral Dissertations

The number of processors embedded in high performance computing platforms is growing daily to solve larger and more complex problems. Hence, parallel runtime environments have to support and adapt to the underlying platforms that require scalability and fault management in more and more dynamic environments. This dissertation aims to analyze, understand and improve the state of the art mechanisms for managing highly dynamic, large scale applications.

This dissertation demonstrates that the use of new scalable and fault-tolerant topologies, combined with rerouting techniques, builds parallel runtime environments, which are able to efficiently and reliably deliver sets of information to a large …

Total Synthesis Of An Analog Of Hydramycin And Derivatization Of Thiol-Terminated Carbohydrates And Development Of A Glycoconjugate Too Set For The Assembly And Presentation Of Carbohydrate Ligands On Surfaces, Medhanit Woldeghiorghis Bahta

Doctoral Dissertations

2-(1,2-Dihydroxy-1-(oxiran-2-yl)ethyl)-11-hydroxy-5-methyl-1Hnaphtho[ 2,3-h]chromene-4,7,12-trione (1), a pyranoanthraquinone isolated from Streptomyces violaceus P950-4, showed a potent antibacterial and cytotoxic activity. A model synthesis for analogs 2-(1,2-dihydroxy-1-(oxiran-2-yl)ethyl)-4H-chromen- 4-one (2) and2-(1-hydroxy-1-(oxiran-2-yl)ethyl)-1H-naphtho[2,3- h]chromene-4,7,12-trione (3) was developed by Dr. David White and Dr. Sarah Headrick. A new analog, 2-(1,2-dihydroxy-1-(oxiran-2-yl)ethyl)-1H-naphtho[2,3- h]chromene-4,7,12-trione (4), was designed to be structurally more similar to hydramycin with –CH2OH functionality on the pyranone ring and anthraquinone skeleton. Therefore, it is expected to have greater anticancer activity than either analogs 2 or 3. This dissertation will cover developments, challenges and solutions in …

Justification Mechanisms In The Conditional Reasoning Test For Aggression And Their Relation To Defense Mechanisms, Cheryl Delaine Barksdale

Doctoral Dissertations

The Conditional Reasoning Test for Aggression (CRT-A; James, 1998; James & McIntyre, 2000) is an inductive reasoning test designed to assess the extent to which individuals use implicit reasoning biases – known as justification mechanisms (JMs) – to justify engaging in behavioral aggression. James and colleagues (James, 1998; James & Mazerolle, 2002; James et al., 2005) have consistently described the CRT-A as an indirect measure of these implicit cognitions, or JMs, but they recently reframed their discussion of the test to emphasize its theoretical grounding in the concept of defense mechanisms (A. Freud, 1936/1966). In particular, they indicated that the …

Cognitive Dissonance: The Apocalyptic Poetics Of Spenser’S Faerie Queene, April Phillips Boone

Doctoral Dissertations

While sixteenth-century citizens of England and the Continent read, interpreted, and appropriated The Book of Revelation for a number of purposes, Edmund Spenser’s primary motivation was to find a source of his poetic theory and practice, as well as his poetic themes and imagery. Spenser began his literary career in 1569 with the anonymous publication of his English translation of Jan van der Noot’s Theatre for Worldlings, which concluded with four sonnets based on scenes from Revelation. My project examines the ways in which Revelation, or Apocalypse as it was frequently called in the period, remained a significant creative fountainhead …

Pasión Y Deseo: Del Amor Y La Sexualidad En Poemas Selectos De Octavio Paz Y Rosario Castellanos, María Cristina Campos Fuentes

Doctoral Dissertations

This dissertation studies selected poems written between 1950 and 1975 by Octavio Paz and Rosario Castellanos, two major Mexican writers of the twentieth century. Paz is considered one of the leading figures of Mexican literature, while Castellanos gained prominence in her homeland as a feminist figure. Using close reading as the predominant approach, this study investigates the complex issues of love and sexuality from the perspective of the poetical voice. It also emphasizes the manner in which the boundaries produced by love and sexuality underscore certain ambiguities. Indeed, these two poets search for identity and happiness in various ways, while …

Fabrication And Analysis Of Polymeric Nanocomposites From Cellulose Fibrils, Qingzheng Cheng

Doctoral Dissertations

A novel process using high-intensity ultrasonication (HIUS) was developed to isolate fibrils from cellulose fibers. The geometrical characteristics of the fibrils were investigated using polarized light microscopy (PLM), scanning electron microscopy (SEM) and atomic force microscopy (AFM). Results show that small fibrils with diameter ranging from about thirty nanometers to several micrometers were peeled from the fibers. The degree of fibrillation of the fibers was significantly increased. The crystallinities or molecular structures of most of the cellulose materials were changed by HIUS treatment.

To evaluate the fibrils degradation by HIUS, a method using AFM was modified and developed to measure …

The Stability Of Carotenogenic Food Colorants And Strategies To Prolong The Shelf Life In Process Cheese Spread, Ann Marie Doneski Craig

Doctoral Dissertations

Food quality is often times measured by the way one perceives the food, particularly with respect to color and texture. Color quality often pre-determines expectation making it an important parameter to understand. The same can be said for textural properties of food. Maintaining color and texture are just two ways in which the shelf-life of food can be measured. One particular product that has experienced problems in this area is processed cheese spread in which the US military uses as part of the Meal, Ready-to-Eat (MRE) rations. The cheese spread is one of the most highly accepted products in the …

Electroanalysis Of Metals In Biological And Environmental Samples At Bismuth Electrodes, Kristie Carter Armstrong

Doctoral Dissertations

An Advanced Oxidation Process (AOP) was designed for the decomposition of organic material in blood as a pretreatment for chromium analysis. Acidified porcine blood was treated with hydrogen peroxide and UV light for 60 min. The rate of decomposition was studied using UV/Vis spectroscopy. It was found that the order of the photolytic reaction with respect to hydrogen peroxide was 0.35. The pretreated blood was subsequently analyzed for chromium content by catalytic adsorptive stripping voltammetry at a bismuth film electrode. The concentration of chromium was determined to be 6.0 " 0.3 parts per billion (ppb). A bismuth bulk electrode was …

Work, Family, And Community In A Triciprocal Relationship: An Exploratory Study Of Enrichment, Cindy L. Crowder

Doctoral Dissertations

The purpose of this study was to expand the field of work-life literature through the introduction of triciprocal enrichment model that examines work-, family-, and community-related support antecedents and satisfaction variables. The main objectives were to incorporate the concept of enrichment and the domain of community into the work-life research providing a more accurate portrayal of the myriad of ways that all three domains interact and affect one another.

Data from 202 respondents were collected, including information on their level of community involvement, their level of enrichment within work, family, and community, their satisfaction on the job, with their family, …

Elements Of Postfeminism: The Current Landscape Of American Politics?, Laura Delorenzo Denison

Doctoral Dissertations

The purpose of this dissertation is to establish the meaning and definition of postfeminism along with an assessment of whether it accurately represents the current era of thinking. It is an historical, descriptive, qualitative analysis of the feminist movement from its inception with the central focus on the newest strand of feminist thought, postfeminism. The progression toward these conclusions entails an outlining of the waves of feminism and the strands of thought within these eras as well as a discussion of third wave feminism, modern feminism and generational differences between the waves. The focus on postfeminism begins with an exploration …

Mems Capacitive Strain Sensing Elements For Integrated Total Knee Arthroplasty Prosthesis Monitoring, Boyd Mccutchen Evans Iii

Doctoral Dissertations

Measuring the in vivo load state of Total Knee Arthroplasty (TKA) components is required to understand the structural environment and wear characteristics of the devices. The ability to acquire this information gives tremendous insight into the mechanics of the joint replacement prosthesis. Data corresponding to normal loads, in-plane loads, shear loads, load center, contact area, and the rate of loading is needed to fully understand the kinematics and kinetics of the orthopedic implant. In this research, a novel sensing system has been developed which is capable of fully characterizing three-dimensional strain and stress at a single location.

Capacitance-based sensors were …

Slipping Backwards: The Supreme Court, Segregation Legislation, And The African American Press, 1877-1920, Kathryn St.Clair Ellis

Doctoral Dissertations

This study discusses the role of Supreme Court decisions in shaping the evolution of Jim Crow and African American newspapers’ reactions to these decisions. The study focuses on the period between the end of Reconstruction and the United States’ entrance into World War I. It looks at several Supreme Court decisions to demonstrate how the Court failed to act as a check on state legislatures’ reactionary undertakings and how these legislatures interpreted the Court’s judgments. Several of the Supreme Court’s decisions served to alert white legislators to the federal government’s limited actions to protect the rights of African American citizens. …

Streaming Effects In Liquid Injection Rocket Engines With Transverse Mode Oscillations, Sean Robert Fischbach

Doctoral Dissertations

This research is an analytical investigation of wave interactions in a simulated liquid rocket engine with uniform injection imposed at the faceplate. Of significant interest are the secondary nonlinear flows, particularly acoustic streaming, induced by transverse wave impingement over the engine injector surface. The corresponding cylindrical chamber has a small length-to-diameter ratio with respect to solid and hybrid rockets. Given their low chamber aspect ratios, liquid thrust engines are known to experience severe tangential and radial oscillation modes more often than longitudinal ones. Experimental evidence demonstrates the production of large peak-to-trough amplitude flow oscillations along with the development of a …

Statistical And Machine Learning Techniques Applied To Algorithm Selection For Solving Sparse Linear Systems, Erika Fuentes

Doctoral Dissertations

There are many applications and problems in science and engineering that require large-scale numerical simulations and computations. The issue of choosing an appropriate method to solve these problems is very common, however it is not a trivial one, principally because this decision is most of the times too hard for humans to make, or certain degree of expertise and knowledge in the particular discipline, or in mathematics, are required. Thus, the development of a methodology that can facilitate or automate this process and helps to understand the problem, would be of great interest and help. The proposal is to utilize …

Laser Surface Structuring Of Alumina, Sandip Pundlikrao Harimkar

Doctoral Dissertations

Alumina ceramic is an important abrasive material for grinding wheels used for rough grinding/machining of materials in manufacturing industry. Purpose of this work is to explore laser surface structuring of alumina grinding wheels for precision machining/grinding of materials by modifying surface microstructure of wheels. Major objective of this work is to study the evolution of surface microstructure and depth of modification such that microstructures/properties of modified wheels can be efficiently tailored based on fundamental understanding of physical processes taking place during laser surface structuring.

Surface structuring of alumina using a continuous wave Nd:YAG laser resulted in significant surface melting and …

Protein Threading For Genome-Scale Structural Analysis, Kyle P. Ellrott

Doctoral Dissertations

Protein structure prediction is a necessary tool in the field of bioinformatic analysis. It is a non-trivial process that can add a great deal of information to a genome annotation. This dissertation deals with protein structure prediction through the technique of protein fold recognition and outlines several strategies for the improvement of protein threading techniques. In order to improve protein threading performance, this dissertation begins with an outline of sequence/structure alignment energy functions. A technique called Violated Inequality Minimization is used to quickly adapt to the changing energy landscape as new energy functions are added. To continue the improvement of …

The Generalized Dea Model Of Fundamental Analysis Of Public Firms, With Application To Portfolio Selection, Xin Zhang

Doctoral Dissertations

Fundamental analysis is an approach for evaluating a public firm for its investmentworthiness by looking at its business at the basic or fundamental financial level. The focus of this thesis is on utilizing financial statement data and a new generalization of the Data Envelopment Analysis, termed the GDEA model, to determine a relative financial strength (RFS) indicator that represents the underlying business strength of a firm. This approach is based on maximizing a correlation metric between GDEA-based score of financial strength and stock price performance. The correlation maximization problem is a difficult binary nonlinear optimization that requires iterative re-configuration of …

Optimal Sizing And Location Of Static And Dynamic Reactive Power Compensation, Wenjuan Zhang

Doctoral Dissertations

The key of reactive power planning (RPP), or Var planning, is the optimal allocation of reactive power sources considering location and size. Traditionally, the locations for placing new Var sources were either simply estimated or directly assumed. Recent research works have presented some rigorous optimization-based methods in RPP. Different constraints are the key of various optimization models, identified as Optimal Power Flow (OPF) model, Security Constrained OPF (SCOPF) model, and Voltage Stability Constrained OPF model (VSCOPF).

First, this work investigates the economic benefits from local reactive power compensation including reduced losses, shifting reactive power flow to real power flow, and …

Nursing In Hell: The Experience Of Providing Care During And After Hurricane Katrina, Marti L. Jordan-Welch

Doctoral Dissertations

Hurricane Katrina, a Category Four hurricane, made landfall on August 29, 2005, along the Gulf Coast of Mississippi and Louisiana. The strength and the extent of winds resulted in the worst destruction and the largest storm surge in the history of the United States. Within hours after the hurricane hit, the earthen levees in New Orleans were breached and 80% of the city became submerged in up to 20 feet of water. Health care workers and patients were stranded in hospitals, where they experienced extreme environmental conditions. The death toll was reported at, 1836 persons, and the damage was estimated …

Electro-Thermal Modeling Of Sic Power Electronic Systems, Hui Zhang

Doctoral Dissertations

As the development of Silicon (Si) semiconductor technology slows down due to its material limitations, more and more attention is being paid to wide bandgap material based semiconductor technology. Silicon Carbide (SiC) has been widely recognized as the material for next generation power electronic devices. However, a great deal of work needs to be done before SiC power devices can be widely applied. This dissertation addresses this need and has conducted research on the modeling of SiC power electronic system. More specifically, a method for system modeling of a SiC power system based on basic physics and device tests is …

Yield And Reliability Analysis For Nanoelectronics, Tao Yuan

Doctoral Dissertations

As technology has continued to advance and more break-through emerge, semiconductor devices with dimensions in nanometers have entered into all spheres of our lives. Accordingly, high reliability and high yield are very much a central concern to guarantee the advancement and utilization of nanoelectronic products. However, there appear to be some major challenges related to nanoelectronics in regard to the field of reliability: identification of the failure mechanisms, enhancement of the low yields of nano products, and management of the scarcity and secrecy of available data [34]. Therefore, this dissertation investigates four issues related to the yield and reliability of …

Investigating The Molecular Basis Of Volatile-Mediated Plant Indirect Defense Against Herbivorous Insects Using Functional And Comparative Genomics, Shuhua Yuan

Doctoral Dissertations

Volatile organic compounds (VOCs) play important roles in plant indirect defense against herbivorous insects by attracting the natural enemies. I first used a tritrophic model system involving rice, rice fall armyworm (Spodoptera frugiperda), and the parasitoid Cotesia marginiventris to discover and characterize the volatile terpenoids and TPS genes involved in the indirect defense of rice against the insect herbivory with integrated functional genomics analyses. Seven rice TPS genes were found to be significantly up-regulated by both microarray and real-time PCR analyses, with one characterized as a linalool synthase and two as sesquiterpene synthases. The products of all three …

Parametric And Non-Parametric Regression Tree Models Of The Strength Properties Of Engineered Wood Panels Using Real-Time Industrial Data, Timothy Mark Young

Doctoral Dissertations

The forest products industry is undergoing unprecedented change from international competition, increasing fiber costs, rising energy prices and falling product prices. Competitive businesses have the key ability to adapt quickly to change through improved knowledge. Among adaptations to change are better product development, improved process efficiency and superior product quality. This dissertation is directly related to improving the knowledge of forest products manufacturers by investigating data mining (DM) methods that improve the ability to quantify causality of sources of variation. A contemporary DM method related to decision theory is decision trees (DTs). DTs are designed for heterogeneous data and are …

Climatic Adaptation And Postcranial Metric Variation In Precontact North America, Kathryn A. King

Doctoral Dissertations

The purpose of this dissertation is to investigate patterns of variation in the postcranial skeleton of prehistoric American populations as they are related to variation in climate. Two ecogeographical rules proposed by Karl Bergmann (1847) and Joel Allen (1877) describe expected patterns of variation with widespread, warm-blooded species. Modern humans in the Old World largely conform to this pattern (Holliday 1997a). This study seeks to explore if the same patterns are present in the New World.

Skeletal material from 25 North American bioarchaeological collections was used in this analysis. A series of 29 measurements of the postcranial skeleton were collected …

Time And Frequency Domain Analyses Of Hydrologic And Stream Water Quality Data, Shesh Raj Koirala

Doctoral Dissertations

The issue of scaling of deterministic properties at various domain levels has become an area of interest for active research. Interpretation of observational data, and similarly hydrologic simulation, require an understanding of how certain deterministic modeling parameters scale from the smaller to larger domains spatially and temporally. Novel approaches to better understand scaling behavior in hydrologic systems and that will result in improved deterministic modeling are necessary to advance the state-of-the-science in hydrologic transport processes, particularly in the areas of microbial concentration and inorganic chemical constituent dynamics. Two primary objectives of this research were i) to determine the statistical relationship …

Physical Properties Of Unconventional Superconductors, Valentina Anatolyevna Kuznetsova

Doctoral Dissertations

In the following development, we attempt to obtain basic physical properties of majority of unconventional superconductors through a Bardeen-Cooper-Schrieffer-type weak-coupling approach. The method we adopted in our study is model-independent. The weak-coupling approach depends only on the symmetry of the coupling, not on its origin. It is known that a general analysis of physical properties of unconventional superconductors is possible, but has not been done yet. The goal of our work is to develop and test such analysis, using available experimental data.

Since paramagnetic limiting for spin-singlet superconductors can be suppressed in superconductors with broken inversion symmetry of crystal lattice, …

Evaluation Of Impacts On Delay, Cycle-Length Optimization, Control Types, And Peak-Hour Factor With The Randomness Of Traffic, Jan-Mou Li

Doctoral Dissertations

Some basic concepts about traffic which are correct in theory may be misinterpreted in practice. Such misinterpretations may lead to a different direction from the ideal operation. This four-part dissertation is designated to examine fundamental concepts in traffic operation, and to validate the impact of randomness on control delays, cycle-length optimization, control types, and the peak-hour factor.

Control delays experienced by drivers is a critical performance measure on interrupted-flow traffic which involves movements at slower speeds and stops on intersection approaches, as vehicles move up in the queue or slow down upstream of an intersection. Since the basic term of …

Temperament And Personality In Preschoolers: Are The Concepts The Same Or Different?, Cathy Grist Litty

Doctoral Dissertations

Individual differences among adults have generally been conceptualized in terms of personality theory and traits and attributed more to life experiences and conditioning than innate dispositions. In contrast, to the more limited extent that individual differences among young children (birth to kindergarten) have been recognized and studied, they have generally been conceptualized in terms of temperament theory and traits, attributed to innate biological programming than to experience.

Recent developments in the field of personality theory begin to blur this distinction, suggesting that individual differences even in young children can be productively studied from the standpoint of personality traits. Specifically, the …