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A Study Of Aging In Male Cortical Bone Using Nanoindentation, Robert Christopher Singleton
A Study Of Aging In Male Cortical Bone Using Nanoindentation, Robert Christopher Singleton
Doctoral Dissertations
The incidence of bone fracture increases with age, due to both declining bone quantity and quality. Towards the goal of an improved understanding of the causes of the age-related decline in the fracture toughness of male cortical bone, nanoindentation experiments were performed on femoral diaphysis specimens from men aged 21-98 years and tibiae from male Fischer F344 rats aged 6, 12, and 24 months (n = 6-11 per age group). Bone is an anisotropic viscoelastic material with a complex hierarchical structure, in which water plays a critical mechanical role by conferring ductility. Because aged bone has been found to have …
Surgical Implant And Tissue Interface, Remigiusz Maciej Grzeskowiak
Surgical Implant And Tissue Interface, Remigiusz Maciej Grzeskowiak
Doctoral Dissertations
Stability of implant-tissue interface is vital for implant integration with adjacent tissue and it influences directly short- and long-term surgical outcome. The literature provides comprehensive research on implants engaged in soft as well as in hard tissues. Various factors have been found to significantly influence the interface stability. This comprehensive work incorporated several research projects with main focus on implant-tissue interface stability, which was evaluated using biomechanical assessment tools such as pullout, four-point bending as well as reverse torque test. Implants were evaluated under ex vivo conditions, immediately after being placed within tissue as well as under in vivo conditions, …