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Chemical Disinfectants For The Inactivation Of The Emerging Foodborne Aichi Virus, Andres Ignacio Arreaza
Chemical Disinfectants For The Inactivation Of The Emerging Foodborne Aichi Virus, Andres Ignacio Arreaza
Masters Theses
Aichi virus (AiV) is an emerging virus responsible for gastroenteritis outbreaks worldwide. Improved decontamination methods are being researched to control AiV spread. The effects of common hard surface disinfectants including benzalkonium chloride (BAC), potassium peroxymonosulfate (KPMS), tribasic sodium phosphate (TSP) as well as sodium metasilicate (SMS) and calcium hypochlorite (Ca(ClO)2) [calcium hypochlorite] against AiV need to be explored. The objective of this research was to determine their effects against AiV using suspension and carrier tests over various contact times at room temperature. Phosphate buffered saline (pH 7.2 as control), 0.64% BAC, 10% KPMS, 10% TSP, 0.16 and 0.3% …
Chemical Disinfectants For Inactivation Of Human Norovirus Surrogates, Cong Cao
Chemical Disinfectants For Inactivation Of Human Norovirus Surrogates, Cong Cao
Masters Theses
Human noroviruses (HNoVs) are considered the leading cause of acute non-bacterial gastroenteritis worldwide. Effective chemical disinfectants to inactivate HNoVs are needed. Since HNoVs cannot be cultivated in the lab, cultivable surrogates, feline calicivirus (FCV-F9) and murine norovirus (MNV-1), are used to determine inactivation using infectivity plaque assays. This study aimed to: 1) determine the ability of benzalkonium chloride (BAC) and potassium peroxymonosulfate (KPMS) to inactivate FCV-F9 and MNV-1 in vitro using suspension and carrier tests under clean and simulated dirty (5% fetal bovine serum) conditions over 1 h at room temperature; 2) determine inactivation of FCV-F9 and MNV-1 in suspension …