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The Relationship Between Calcium Intake, Obesity, And Cardiovascular Disease Risk Factors: The Jackson Heart Study, Marjuyua Lartey-Rowser

Dissertations

Cardiovascular disease (CVD) is a major health risk in the United States. Major indicators of CVD risk include obesity, blood lipids, and blood pressure. Modifiable risk factors associated with CVD include body composition (body mass index and waist circumference), serum lipids, and blood pressure. Data suggest calcium intake may play a role in regulation of weight, serum lipids, and blood pressure. The purpose of this study was to assess relationships of dietary calcium intake with weight status, and cardiovascular disease risks in African American population participating in the Jackson Heart Study.

The subjects included 4,267 African American adults ages 21-95 …

Mechanisms Of Regulation Of Proximal Tubule Sodium Transporters In Obesity-Induced Hypertension, Marta A. Ambrozewicz

Theses and Dissertations in Biomedical Sciences

Hypertension is one of the common complications of obesity. Using a rat model of diet induced obesity and hypertension we investigated some of the mechanisms that are involved in regulation of blood pressure in obesity. The first aim of this study was to determine the role of proximal tubule transporters on the renal sodium handling in obese hypertensive (OP) and lean normotensive (OR) rats. An acute increase in renal perfusion pressure resulted in a blunted natriuretic response in OP vs. OR rats and indicated that increased sodium reabsorption in the proximal tubule is casual, at least in part, for hypertension …

Transcriptional Regulation Of Adipocyte Function, Kivanc Birsoy

Student Theses and Dissertations

The increased white adipose tissue mass associated with obesity is the result of both hyperplasia and hypertrophy of adipocytes. While adipocyte development and transcriptional processes are well studied in vitro, regulation of in vivo genes (such as leptin), the identity of the adipocyte progenitor cells and the development of the adipose organ have not been defined invivo. In this thesis, firstly KLF4 was discovered to be an essential early regulator of adipogenesis. KLF4 together with Krox20 cooperatively transactivates C/EBPβ, suggesting that KLF4 and Krox20 are part of an immediate early transcriptional network. This network is upregulated in a lipodystrophic animal …

Implication For The Role Of Leptin-Induced Signaling As A Negative Regulator Of Dendritic Cell Function, Oscar Ramirez

Open Access Theses & Dissertations

The incidence of obesity among the distinct world populations has become an ever growing concern. Central to the regulation of obesity is the adipocyte-derived hormone, and in more recent years cytokine, leptin. Leptin plays a central role in the maintenance of food consumption as well as the efficient use of peripheral energy stores. Leptin exerts its physiological role in energy homeostasis by regulating the expression of orexigenic peptides in the central nervous system. However, recent research has implicated leptin in other physiological roles including those of the immune system. As a pleiotropic cytokine, the absence of leptin has been shown …

Fit Camp A Behavioral Weight Loss Program The Effects Of Self-Monitoring, Social Support, Attendance, And Motivation, Erin Marie Murnan

University of Kentucky Master's Theses

Almost half of Americans between 17 and 24 years of age are enrolled in higher education. College is an important life transition period when many young adults establish independence and adopt lasting behavior patterns, especially with regard to diet and physical activity. The first years of college are often associated with weight gain therefore making weight loss and weight gain prevention interventions necessary in this population. Behavioral weight loss programs (BWLP) have shown to be effective in adults, however, to our knowledge, there have been no reports of BWLP focused solely on college-aged young adults. This study compared a 10-week …

The Effects Of Eating Behaviors And Exercise Patterns On The Processing Of Food And Exercise Related Stimuli, Carrie Potter

Honors Theses

The effectiveness of Cognitive Behavioral Therapy (CBT) for eating disorders has established a link between cognitive processes and unhealthy eating behaviors. However, the relationship between individual differences in unhealthy eating behaviors that are not related to clinical eating disorders, such as overeating and restrained eating, and the processing of food related verbal stimuli remains undetermined. Furthermore, the cognitive processes that promote unhealthy and healthy exercise patterns remain virtually unexplored by previous research. The present study compared individual differences in attitudes and behaviors around eating and exercise to responses to food and exercise-related words using a Lexical Decision Task (LDT). Participants …

A Descriptive Study Of The Diet And Physical Activity Practices Of Overweight And Obese College Students Enrolled In A Weight Loss Program, Laura Brooke Walters

University of Kentucky Master's Theses

The effect of weight gain on college students may lead to physical and emotional problems that could continue into adulthood. Identifying behavioral, demographic, and psychological factors that impact college student’s weight status could aid in developing programs to help reduce weight and prevent weight gain in overweight and obese college students. This study evaluated the dietary habits, physical activity, and psychosocial characteristics of college students entering a university-sponsored weight loss program. Results suggest that the majority of participants have experienced weight gain in the past year and none have experienced weight loss. The student’s diets tended to include less than …