Digital Commons Network^™

Proposed Charlotte To Atlanta High-Speed Passenger Rail Line: An Economic, Infrastructural, And Developmental Analysis In The Upstate Of South Carolina, Ian C. Macurda, Kimberly Whitehead

SC Upstate Research Symposium

This research paper is an in-depth analysis of the high-speed passenger rail line proposed between Charlotte, NC and Atlanta, GA and its impact on the economy, infrastructure, and future development of the Upstate of South Carolina. Currently, passenger rail service between Charlotte and Atlanta is offered on Amtrak at late hours throughout the night on its long-distance passenger rail line The Crescent from New York City, NY to New Orleans, LA. The train is often delayed and is operating at a deficit for Amtrak, like most of their long-distance routes. Traffic on Interstate 85 through the Upstate is another issue …

A Longitudinal Study Of The Development Of Social Anxiety In Young Autistic Children, Gillian K. Marshall

Senior Theses

Social anxiety is a prevalent anxiety disorder marked by fear and discomfort in social situations where scrutiny or evaluation by others is anticipated. This thesis investigates the interplay between social anxiety and autism spectrum disorder (ASD), a neurodevelopmental condition characterized by social and communication challenges. Individuals with ASD often face heightened levels of anxiety, intensifying their social difficulties and impeding their social development. Early identification of social anxiety symptoms, particularly in ASD children, is crucial for timely intervention and improved outcomes. However, diagnosing social anxiety in preschool-aged children, especially those with ASD, presents challenges due to the complexity of symptoms …

University Libraries Impact Report 2023, Leslie Haynsworth, Kristine Hontz

University Libraries Policies and Reports

A report on notable activities in University of South Carolina Libraries in 2023.

Donation Intention In Current Students: An Analysis Of University Engagement And Sense Of Place In Future Athletic, Academic, And Split Donors, Charlie Brunette, Ngoc Vo, Nicholas M. Watanabe

Journal of Issues in Intercollegiate Athletics

No abstract provided.

Teacher Observations As Professional Development Opportunities, Ashton Carrie Padgett

Theses and Dissertations

This research project sought to understand how the complexities and challenges of offering high-quality professional development district-wide impacted teachers’ ability to implement their new learning. The literature posits that to be considered effective, professional development must include six distinct design elements: (1) Data driven, (2) Incorporates active learning utilizing adult learning theory, (3) Supports collaboration, (4) Context-Specific, (5) Feedback-centered, and (6) Supported by principal leadership (Darling Hammond et al., 2017, p. 4). While each of these design elements seems appropriate and rooted in best practices, when planning professional development, the scheduling and unique circumstances of secondary schools makes incorporating these …

Reconceptualizing Informal Learning In An Online Learning Environment, Silvia Clark

Theses and Dissertations

In 2020, many organizations moved their formal training programs to an online learning context due to COVID-19. Informal learning, which refers to activities that are self-guided and occur independently outside of formal learning contexts has gained significant interest among researchers and practitioners in the past two decades as it has been identified as the primary type of learning in today's organizations. Despite the increasing interest in informal learning, no attempt has been made to examine and understand informal learning in an online learning environment.

This dissertation provides an integrative review of prior work on formal and informal learning in online …

Neurodevelopmental Processes In The Prefrontal Cortex Derailed By Chronic Hiv-1 Viral Protein Exposure, Kristen A. Mclaurin, Hailong Li, Rosemarie M. Booze, Charles F. Mactutus

Faculty Publications

Due to the widespread access to, and implementation of, combination antiretroviral therapy, individuals perinatally infected with human immunodeficiency virus type 1 (HIV-1) are living into adolescence and adulthood. Perinatally infected adolescents living with HIV-1 (pALHIV) are plagued by progressive, chronic neurocognitive impairments; the pathophysiological mechanisms underlying these deficits, however, remain understudied. A longitudinal experimental design from postnatal day (PD) 30 to PD 180 was utilized to establish the development of pyramidal neurons, and associated dendritic spines, from layers II-III of the medial prefrontal cortex (mPFC) in HIV-1 transgenic (Tg) and control animals. Three putative neuroinflammatory markers (i.e., IL-1β, IL-6, and …

Developmental Regression Analysis And Investigation Of Genotype Correlations In Individuals With Classic Rett Syndrome, Aubrey Lynn Rose

Theses and Dissertations

Rett syndrome (RTT) is a neurodevelopmental disorder impacting 1 in 10,000 females worldwide, making it one of the most common causes of complex disability in girls. RTT is caused by pathogenic variants in the MECP2 gene and is characterized by developmental regression, stereotypical hand movements, and an abnormal gait. Despite consistency in the presence of these core features, a wide range of features and varying severity can be observed in girls with RTT. Similarly, the particular type of MECP2 variant present also differs between patients. Previous studies have assessed correlations between genotype and phenotype in patients with RTT. While past …

Choline Supplementation And Dna Methylation In The Hippocampus And Prefrontal Cortex Of Rats Exposed To Alcohol During Development, Nicha K. H. Otero

Theses and Dissertations

Fetal Alcohol Spectrum Disorders (FASD) refers to the effects of alcohol exposure during development on individuals. Some of the most frequent deficits seen in children with FASD and in animal models of FASD are spatial memory impairments and impaired executive functioning, which are likely related to alcohol-induced alterations of the hippocampus and medial prefrontal cortex (mPFC), respectively. Choline, a nutrient supplement, has been shown in a rat model to ameliorate some of alcohol‟s teratogenic effects and this effect may be mediated through choline‟ effects on DNA methylation. This study used a rat model of FASD to investigate the underlying mechanisms …

Promoting Critical Consciousness: The Role Of Positive Youth Development Programming, Mackenzie Jaclyn Hart

Theses and Dissertations

This study examined the role of positive youth development programming and individual-level characteristics in promoting critical reflection (CR) in youth and adolescent participants. CR refers to the analytical component of critical consciousness (CC), or the exercise of challenging institutional practices that systemically marginalize or oppress certain subgroups. Survey and interview data were analyzed from at-risk high school students (N=250) participating in an after-school program across six sites in urban areas in the United States. Multiple regression models were used to predict the development of CR, and interviews were examined to look for themes related to quantitative findings. Results support that …

Promoting Self-Reflection Of Foreign Language Teachers Through Professional Development: An Action Research Dissertation, Hanan Khaled

Theses and Dissertations

This explanatory mixed-method action research describes how a social constructivist professional development program impacts self-reflection of foreign language teachers at the Defense Language Institute Foreign Language Center (DLIFLC). The problem is that traditional professional development for foreign language teachers does not improve self-reflection. Despite their individual differences and qualifications, most teachers receive traditional in-service professional development (Darling-Hammond, Hyler, Gardner, & Espinoza, 2017) on a specific topic and have no time to reflect on their existing practices, newly presented concepts, or students' responses to instruction. The effectiveness of such professional development is questionable (Darling-Hammond, Wei, Andree, Richardson, & Orphanos, 2009; Penuel, …

Assessing Readiness For A Physical Activity Intervention In Positive Youth Development Afterschool Programs, Brittany Skiles Cook

Theses and Dissertations

Physical inactivity has been identified as a primary health threat to youth, and existing afterschool programs (ASP) are a promising context for implementing physical activity (PA) interventions. However, few PA interventions have been effective and generalizability of programs has been poor. Assessing organizational readiness during the testing of a PA intervention can help inform generalizability and sustainability. The R=MC2 heuristic separates readiness into motivation, innovation-specific capacity, and general capacity, each of which are further divided into subcomponents. The current multiple-case study pilot tests the feasibility and effectiveness/efficacy of a readiness assessment tool based on R=MC2 developed for the Connect through …

A Development Of Transfer Entropy In Continuous-Time, Christopher David Edgar

Theses and Dissertations

The quantification of causal relationships between time series data is a fundamen- tal problem in fields including neuroscience, social networking, finance, and machine learning. Amongst the various means of measuring such relationships, information- theoretic approaches are a rapidly developing area in concert with other methods. One such approach is to make use of the notion of transfer entropy (TE). Broadly speaking, TE is an information-theoretic measure of information transfer between two stochastic processes. Schreiber’s 2001 definition of TE characterizes information transfer as an informational divergence between conditional probability mass func- tions. The original definition is native to discrete-time stochastic processes …

The Empty Mill: An Analysis Of A Disappearing Linchpin Of Southern Society And Its Hope For A Preserved Future, Matthew South Bright

Senior Theses

August Kohn’s report, The Cotton Mills of South Carolina, published in The News and Courier in 1907, attempted to document the impact that cotton mills in South Carolina had on its places, people, and growth. Over 100 years since the lists publishing, a comprehensive evaluation of the mills had not been undertaken. This thesis endeavored to evaluate the current status of the South Carolina cotton mills from Kohn's 1907 list. Of the original 141 mills, 120 were successfully located and their status mapped in a Geographic Information System (GIS). Sixty-six were found demolished, twenty-five were standing, and twenty-nine were developed …

Stimulating Canonical Wnt Signaling In Pituitary Progenitors Inhibits Differentiation Of Hormone Cell Types, Tanner F. Coleman

Senior Theses

The mouse pituitary gland secretes hormones that regulate many physiological processes including growth, stress response, and reproduction. The canonical WNT signaling pathway, activation of which results in nuclear accumulation of β-CATENIN and transcription of target genes including LEF1, is crucial for proper development of the pituitary gland. Pituitary progenitors that lack β-CATENIN at embryonic day of development 8.5 (E8.5) cannot form three of the six cell types of the anterior pituitary that produce growth hormone (GH), thyroid stimulating hormone (TSH), and prolactin (PRL). Additionally, stimulating canonical WNT signaling through creation of degradation-resistant β-CATENIN at E9.5 causes pituitary tumors and results …

Development Of Models And Solution Methods For Different Drayage Applications, Samaneh Shiri

Theses and Dissertations

In the last decades, intermodal freight transport is becoming more attractive in the global supply chains and freight transport policy makings. Intermodal freight transport provides a cost-effective, reliable, and efficient movement of freight by utilizing the strengths of different transport modes. The initial and final segment of intermodal freight transport, performed by truck, is known as “drayage.” The scheduling of truck movements in drayage operation within the service area of an intermodal terminal is an operational problem which leads to a truck scheduling problem that determines the efficient schedule of trucks while satisfying all transportation demands and constraints. Drayage accounts …

The Design, Development, And Evaluation Of A Usable And Privacy-Enhanced Telepresence Interface For Older Adults, Xian Wu

Theses and Dissertations

Maintaining health and wellness while aging-in-place independently is crucial for older adults. Telepresence technology can be potentially beneficial for this target population to stay socially connected. However, this technology is not specifically designed for older adults. For this target population to adopt such technology successfully, it is important to ensure that they do not experience usability barriers. This research uses HCI/HRI concepts and technology design principles for older adults to design, develop and test telepresence user interfaces (UI). This addresses the following research questions: 1): What are the essential usability and privacy-enhanced features needed to inform the design and development …

Exploring The Role Of Schema Development And Its Impact Within The Digital Vocabulary Application Quizlet, Jana M. Tolleson

Theses and Dissertations

The purpose of this action research study was to ascertain the possible impact of using schema development strategies and the digital application Quizlet on student learning perspectives and achievement in a mid-level social studies classroom. U.S. schools are highly influenced by state standardized testing based on standards-driven curriculum that reinforces basic recall and recognition. School curriculum should be focused on higherlevel thinking skills such as critical thinking, social negotiation, and self-directed learning. The identified problem of practice of this study explored and described the use of technology at a basic level. Students are exploiting technology by copying and pasting information …

Development Of Bimetallic Catalysts For Dry Reforming Of Methane And Hydrogenation Of Succinic Acid, Jayson Michael Keels

Theses and Dissertations

Advances in natural gas recovery have greatly impacted the global economy; the abundant supply of gas has revealed new opportunities and challenges in a wide range of markets within the fuels and chemicals industries. One such opportunity exists with the overabundance of gas from remote wells that is flared or emitted because of the high costs associated with transportation of a chemical with such a high molar volume. A possible solution is an on-site process to convert gas to higher value chemicals that are liquid at standard conditions, and can more easily be transported. As a first step, CO2 from …

Development Of A High-Resolution Spatial Heterodyne Libs Spectrometer, Kevin A. Dudley

Theses and Dissertations

Laser-Induced Breakdown Spectroscopy (LIBS) is an atomic emission technique that uses a pulse laser to ablate a sample and form a plasma. Atomic emissions from the plasma provide unique elemental characteristics regarding the composition of the sample. The technique produces valuable qualitative results, but the accuracy of quantitative analyses is hindered by spectral line broadening mechanisms and laser pulse reproducibility, among other factors. The Spatial Heterodyne Spectrometer (SHS) is a high-resolution spectrometer with very high light throughput, and its use to LIBS is currently limited to two peer-reviewed publications. In the following work a high resolution SHS is developed and …

Development Of A Supplier’S Delivery Time And Delivered Quality Performance Index And Assessment Of Alternative Decisions Regarding Underperforming Suppliers For The Aerospace Industry, Clint Saidy

Theses and Dissertations

This study investigates current practices of supplier’s delivery assessment so that a comprehensive index and a cost function model could be properly developed. Following a thorough literature review, a framework was created based on a penalty cost function that integrates both suppliers’ ability to deliver on time, as well as suppliers’ capability to deliver good quality. Afterward, suppliers could then be ranked and placed either in good standing, or transversely on probation. Underperforming suppliers face three potential outcomes based on current literature: (1) switching supplier, (2) increase collaboration, (3) maintaining the status quo. The decision vis-à-vis failing suppliers is based …

Effect Of Resveratrol On The Development Of Eczema, Christopher Carlucci

Theses and Dissertations

Atopic dermatitis is a type of eczema characterized by chronic inflammation of the skin, affecting millions of people worldwide. Resveratrol, a naturally occurring stilbenoid, is widely believed to exhibit beneficial effects on a host of chronic diseases. Although some previous studies have aimed to evaluate the effects of resveratrol on the pathogenesis of atopic dermatitis, this relationship remains ill-defined. We have previously established that mast cell activation, remodeling, and cellular infiltration in the hypodermis all begin prior to the IgE-mediated immune response in an atopic dermatitis mouse model, and that this early pathogenesis is directly related to an increase in …

The Impact Of Number Talks On Third-Grade Students’ Number Sense Development And Mathematical Proficiency, Nicole D. Gaillard

Theses and Dissertations

This action research study employed a mixed-methods design to examine the impact of a number talks intervention on the number sense development and mathematical proficiency of students in one third-grade mathematics class. The number talks strategy was also studied to determine its impact on third-grade students’ development of a productive mathematical disposition. Number sense is “a person’s general understanding of numbers and operations along with the ability and inclination to use this understanding in flexible ways to make mathematical judgments and to develop useful strategies for handling numbers and operations” (McIntosh, Reys, & Reys, 1992, p. 3). This eight-week study …

More Than Meets The Eye: Development Of A Sport Event Stimuli And Destination Image Fit Scale, Yongjin Hwang

Theses and Dissertations

Much research demonstrates an impact of sensory experience on sports fans’ satisfaction with live sporting events (Lee, Heere, & Chung, 2013; Lee, Lee, Seo, & Green, 2012). It was, however, not studied how to enhance those sense-centric experiences. One possible approach would be to utilize unique region-based characteristics to design unforgettable and emotionally engaging experiences. Most sporting events are location-based, and venues are also considered as a landmark of the area where they are placed. Consequently, we can create a natural link between sporting events and the hosting cities or regions. Visual designs, musical contents, famous local food, and signature …

The Aspergillus Flavus Homeobox Gene, Hbx1, Is Required For Development And Aflatoxin Production, Jeffrey W. Cary, Pamela Y. Harris-Coward, Leslie Scharfenstein, Brian M. Mack, Perng-Kuang Chang, Qijian Wei, Matthew Lebar, Carol Carter-Wientjes, Rajtilak Majumdar, Chandrani Mitra, Sourav Banerjee, Anindya Chanda

Faculty Publications

Homeobox proteins, a class of well conserved transcription factors, regulate the expression of targeted genes, especially those involved in development. In filamentous fungi, homeobox genes are required for normal conidiogenesis and fruiting body formation. In the present study, we identified eight homeobox (hbx) genes in the aflatoxin-producing ascomycete, Aspergillus flavus, and determined their respective role in growth, conidiation and sclerotial production. Disruption of seven of the eight genes had little to no effect on fungal growth and development. However, disruption of the homeobox gene AFLA_069100, designated as hbx1, in two morphologically different A. flavus strains, CA14 and AF70, resulted in …

The Development Of Novel Hybridized Hyaluronic Acid Biomaterials For Applications In Tissue Engineering And Controlled Drug Delivery, Panita Maturavongsadit

Theses and Dissertations

This thesis is focused on the development of novel hybridized biomaterials for applications in tissue engineering and controlled drug delivery. Two types of materials used in my research are biopolymers and nanomaterials. Hyaluronic acid (HA), a natural polymer commonly found in extracellular matrix (ECM), was the primary polymer used in my research due to biocompatibility, biodegradability and the ease of manipulation to offer a wide range of physical and mechanical properties. Meanwhile, the nanomaterials, including Tobacco mosaic virus (TMV), gold nanorods and graphene, provide attractive properties, such as a nanoscale topography, biochemistry, high surface area, and special chemical and electrical …

Development Of A Sandwich Hybridization Assay For The Harmful Cyanobacteria Microcystis Spp., Nicole M. Dearth

Theses and Dissertations

Cyanobacteria are responsible for the largest number of harmful blooms (HABs) worldwide. HABs caused by the genus Microcystis pose public health threats because they often occur within close proximity to humans and produce microcystin (hepatotoxin), which can contaminate drinking water and recreational areas. Novel molecular techniques facilitate monitoring, ‘early warnings’ of HAB events, and appropriate management responses. Sandwich hybridization assay (SHA), the technique considered here, directly (no amplification) identifies and quantifies planktonic species using ribosomal RNA (rRNA)-targeted oligonucleotides. This project developed SHA for Microcystis 16S rRNA and validated the assay using laboratory cultures and samples from a multi-specific cyanobacteria bloom …

Development Of An Estrogen-Related Dietary Pattern And Lifestyle Score To Examine Breast Cancer Risk In Postmenopausal Women, Mark Andrew Guinter

Theses and Dissertations

Introduction: Studies examining the association between individual dietary components and breast cancer have been inconclusive. The use of dietary patterns is a holistic approach which may yield stronger associations. We sought to develop a dietary pattern based on an estrogen metabolite (EM) profile hypothesized to increase breast cancer risk (high unconjugated estradiol and low ratio of 2- to 16-hydroxylated EMs (2/16 ratio)). This estrogen-related dietary pattern (ERDP) was examined for associations with postmenopausal breast cancer in two study populations and was incorporated into an estrogen-related lifestyle score (ERLS) with other modifiable risk factors for breast cancer.

Methods: EM …

Enhancing Innovation In The Ugandan Agri-Food Sector: Progress, Constraints, And Possibilities, Travis Lybbert, Kritika Saxena, Julius Ecuru, Dick Kawooya, Sacha Wunsch-Vincent

Faculty Publications

No abstract provided.

Perceived Emotional Invalidation In A Developmental Context: Does Gender Matter?, Brian B. Johnson

USC Aiken Psychology Theses

Emotional invalidation is the dismissal, minimization, or punishment of an individual’s emotional experience (Linehan, 1993). Although it has been sparsely studied, the research that has been conducted indicates that it is likely implicated in a multitude of psychopathology and adjustment issues. The current study had three main objectives. The first of these was to investigate the current perceptions of emotional invalidation in a peer interaction for emerging adults and how that is predicted by gender, perceptions of childhood emotional invalidation via caregivers, and gender of the caregivers. The second objective of this study was to investigate the propagation of emotionally …