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Articles 1 - 9 of 9
Full-Text Articles in Entire DC Network
Synthesis, Characterization, Molecular Docking, And Preliminary Antimicrobial Evaluation Of Thiazolidinone Derivatives, Sarmad S. Hussein, Karima F. Ali, Fouad A. Al-Saady
Synthesis, Characterization, Molecular Docking, And Preliminary Antimicrobial Evaluation Of Thiazolidinone Derivatives, Sarmad S. Hussein, Karima F. Ali, Fouad A. Al-Saady
Palestinian Medical and Pharmaceutical Journal
Several derivatives carrying thiazolidine-4-one pharmacophore were prepared to evaluate their antimicrobial activities. The set of compounds were shown to possess potential activities as determined by molecular docking studies for both candidal (14-alpha demethylase) and bacterial enzymes (Penicillin binding protein of E. coli). In vitro antimicrobial activities were also performed to confirm the molecular docking results. Molecular characterization by spectral techniques (FT-IR, 13C NMR and 1H NMR) was carried out to confirm the identity of the synthesized compounds. The synthesized compounds were evaluated for antibacterial and anticandidal activity by comparing them with the reference drugs (positive controls) ceftriaxone …
Potential Enhancement Of Microbial Disinfection Using Oxygen Enriched Cold Atmospheric-Pressure Argon (Ar/O2) Plasma Jet, Waleed O. Younis, Mahmoud M. Berekaa, Mostafa A. Ellbban, Abdel-Sattar S. Gadallah, Jamal Q. Almarashi, Abdel-Aleam H. Mohamed
Potential Enhancement Of Microbial Disinfection Using Oxygen Enriched Cold Atmospheric-Pressure Argon (Ar/O2) Plasma Jet, Waleed O. Younis, Mahmoud M. Berekaa, Mostafa A. Ellbban, Abdel-Sattar S. Gadallah, Jamal Q. Almarashi, Abdel-Aleam H. Mohamed
Karbala International Journal of Modern Science
Oxygen activated cold-atmospheric-pressure-argon plasma jet (APPJ) has gained prominence over the regular argon plasma especially in disinfection and decontamination. As an objective of the current research, an oxygen-enriched argon system was built, where plasma produced through a vessel metallic tube that is introduced into alumina one. A sinusoidal high voltage signal of 25 kHz was used to generate plasma jet. Potential impact of oxygen enriched APP jet (Ar/O2) in decontamination of different microbial cells was observed. For examination, suspension of each tested microbe was placed in contact with plasma jet nearly 10 mm away from the jet nozzle …
Hospital And Patient Responses To Medicare Policy, Ricardo Ang
Hospital And Patient Responses To Medicare Policy, Ricardo Ang
AYSPS Dissertations
In chapter 1 of this work, I estimate the causal impact of Section 3008 of the Affordable Care Act (ACA) on its targeted infection outcomes. This policy, implemented in October 2014, imposes a 1% reduction in the Medicare reimbursements of hospitals that perform poorly based on a hospital-acquired infection (HAI) measure. A limited body of literature evaluates the impact of this policy in a primarily descriptive manner. Using patient discharge data from the National Inpatient Sample (NIS), Healthcare Cost and Utilization Project (HCUP), Agency for Healthcare Research and Quality and a difference-in-differences identification strategy, I contribute to the literature by …
Analysis Of Antibiotic Sensitivity Patterns In Pasteurellaceae Family Isolates: A Microbial And Molecular Investigation, Jillian Barron
Analysis Of Antibiotic Sensitivity Patterns In Pasteurellaceae Family Isolates: A Microbial And Molecular Investigation, Jillian Barron
Honors Scholar Theses
Bacteria in the Pasteurellaceae family are known to cause disease in both human and animal species. Like all species of bacteria, the pathogens in the Pasteurellaceae family evolve and acquire antimicrobial-resistant traits. Antimicrobial resistance of bacteria is a significant public health concern, as treatment of resistant pathogens becomes more difficult, if not impossible, with current medical capabilities. In this project, phenotypic and genotypic analyses were performed on Pasteurellaceae family isolates sourced from the Connecticut Veterinary Medical Diagnostic Laboratory. Phenotypic antibiotic sensitivity patterns of each isolate were assessed against a panel of antibiotics through a Kirby-Bauer disk diffusion test. Disk diffusion …
Determination Of Antibiotic Resistance In Salmonella Typhimurium And Salmonella Kentucky Serotypes Of Animal Origin Using Conventional And Molecular Methods, Zeynep Şik, Mehmet Akan
Determination Of Antibiotic Resistance In Salmonella Typhimurium And Salmonella Kentucky Serotypes Of Animal Origin Using Conventional And Molecular Methods, Zeynep Şik, Mehmet Akan
Turkish Journal of Veterinary & Animal Sciences
The high incidence of multidrug-resistant Salmonella Typhimurium and Salmonella Kentucky isolates is a concern for human and animal health. This study aimed to investigate the antibiotic resistance determinants of a total of 150 S. Typhimurium and S. Kentucky isolates obtained from cows, calves, lambs, and poultry. Salmonella isolates were tested against 13 different antimicrobials using the Kirby-Bauer disc diffusion method, and genotypic antimicrobial resistance determinants were investigated by polymerase chain reaction. Significant differences were detected among serovars for gentamicin, streptomycin, ampicillin, sulfonamide, nalidixic acid, ciprofloxacin, and tetracycline resistance, with the rates of resistance to these antibiotics being determined to be …
Salmonella In The Environment: A Review On Ecology, Antimicrobial Resistance, Seafood Contaminations, And Human Health Implications, Mohammad Maruf Billah, Md Saydur Rahman
Salmonella In The Environment: A Review On Ecology, Antimicrobial Resistance, Seafood Contaminations, And Human Health Implications, Mohammad Maruf Billah, Md Saydur Rahman
School of Earth, Environmental, and Marine Sciences Faculty Publications and Presentations
Salmonella is a genus of Gram-negative bacteria that is responsible for numerous food poisoning outbreaks worldwide. With 93.8 million food-borne illnesses and 155,000 fatalities annually, it has emerged as a significant global public health issue. There are currently more than 2,500 distinct Salmonella serotypes, and more than half of them are associated with Salmonella enterica. An increasing global public health concern for humans and animals is antimicrobial resistance by Salmonella species worldwide. Salmonella infections can be lethal; conditioned with an increased prevalence of multi-drug resistant (MDR) strains in the future. The emergence of MDR Salmonella serotypes is considerably …
Emergence Of Highly Resistant Candida Auris In The United Arab Emirates: A Retrospective Analysis Of Evolving National Trends, Jens Thomsen, Najiba M. Abdulrazzaq, Abderrahim Oulhaj, Peter S. Nyasulu, Adnan Alatoom, David W. Denning, Fatima Al Dhaheri, The Uae Amr Surveillance Consortium, Godfred Antony Menezes, Carole Ayoub Moubareck, Abiola Senok, Dean B. Everett
Emergence Of Highly Resistant Candida Auris In The United Arab Emirates: A Retrospective Analysis Of Evolving National Trends, Jens Thomsen, Najiba M. Abdulrazzaq, Abderrahim Oulhaj, Peter S. Nyasulu, Adnan Alatoom, David W. Denning, Fatima Al Dhaheri, The Uae Amr Surveillance Consortium, Godfred Antony Menezes, Carole Ayoub Moubareck, Abiola Senok, Dean B. Everett
All Works
The Centers for Disease Prevention and Control lists Candida auris, given its global emergence, multidrug resistance, high mortality, and persistent transmissions in health care settings as one of five urgent threats. As a new threat, the need for surveillance of C. auris is critical. This is particularly important for a cosmopolitan setting and global hub such as the United Arab Emirates (UAE) where continued introduction and emergence of resistant variant strains is a major concern. The United Arab Emirates has carried out a 12 years of antimicrobial resistance surveillance (2010–2021) across the country, spanning all seven Emirates. A retrospective analysis …
Epidemiology And Antimicrobial Resistance Trends Of Acinetobacter Species In The United Arab Emirates: A Retrospective Analysis Of 12 Years Of National Amr Surveillance Data, Jens Thomsen, Najiba M. Abdulrazzaq, Hussain Alrand, The Uae Amr Surveillance Consortium, Dean B. Everett, Abiola Senok, Godfred A. Menezes, Carole Ayoub Moubareck
Epidemiology And Antimicrobial Resistance Trends Of Acinetobacter Species In The United Arab Emirates: A Retrospective Analysis Of 12 Years Of National Amr Surveillance Data, Jens Thomsen, Najiba M. Abdulrazzaq, Hussain Alrand, The Uae Amr Surveillance Consortium, Dean B. Everett, Abiola Senok, Godfred A. Menezes, Carole Ayoub Moubareck
All Works
Introduction: Acinetobacter spp., in particular A. baumannii, are opportunistic pathogens linked to nosocomial pneumonia (particularly ventilator-associated pneumonia), central-line catheter-associated blood stream infections, meningitis, urinary tract infections, surgical-site infections, and other types of wound infections. A. baumannii is able to acquire or upregulate various resistance determinants, making it frequently multidrug-resistant, and contributing to increased mortality and morbidity. Data on the epidemiology, levels, and trends of antimicrobial resistance of Acinetobacter spp. in clinical settings is scarce in the Gulf Cooperation Council (GCC) and Middle East and North Africa (MENA) regions. Methods: A retrospective 12-year analysis of 17,564 non-duplicate diagnostic Acinetobacter spp. isolates …
Genome-Based Pathogenicity Potential Of Salmonella Isolated From Diverse Sources, Jared Mr Crocco
Genome-Based Pathogenicity Potential Of Salmonella Isolated From Diverse Sources, Jared Mr Crocco
Theses and Dissertations (Comprehensive)
Bacterial human pathogens are among the leading causes of death around the world, especially in low income and developing countries. One important element in a bacterium’s ability to cause disease are genes that directly contribute to pathogenicity called virulence factors. A second significant aspect are antimicrobial resistance genes which allow microorganisms to persist in the presence of antimicrobial agents. In this project I aimed to determine if Salmonella isolated from different sources differed in pathogenicity profiles based on the complement of genes identified through genomic analysis. Accordingly, Salmonella genomes were organized into 8 groups: animal, clinical, human, environmental, food, water …