Digital Commons Network^™

Clarity On Cronbach’S Alpha Use, Jack Barbera, Nicole Naibert, Regis Komperda, Thomas C. Pentecost

Chemistry Faculty Publications and Presentations

The Cronbach’s alpha (α) statistic is regularly reported in science education studies. However, recent reviews have noted that it is not well-understood. Therefore, this commentary provides additional clarity regarding the language used when describing and interpreting alpha and other estimates of reliability.

Toward Improved Characterization Of Biologically Relevant Isomeric And Isobaric Ions On Mass Spectrometry-Based Platforms, Baku Acharya

Theses and Dissertations

Mass spectrometry has frequently been employed in the analysis of biologically relevant molecules; however, mass spectrometry alone may not always be sufficient for the differentiation and characterization of isomeric and isobaric ions. In this work, infrared multiple photon dissociation (IRMPD) spectroscopy and ion mobility spectrometry (IMS) were evaluated as complementary techniques for the characterization and separation of isomeric and isobaric ions of biological relevance. In the first project, analysis of experimental IRMPD spectroscopy data shows that this technique is useful in the differentiation of hydroxyproline isomers. Absorption bands allow for the differentiation of three isomeric species: 1640 cm-1 (trans-4-hydroxyproline), 1718 …

Computational Chemistry Investigation Of Gas-Phase Structures, Infrared Spectroscopy, And Dissociation Pathways Of Isomeric Molecules, Widana Kaushalya

Theses and Dissertations

While chemical isomers typically have distinct properties, differentiating between them is often an analytical challenge, especially for mass spectrometric methods. Infrared multiple photon dissociation (IRMPD) spectroscopy and ion mobility spectrometry (IMS) can be useful in analysis of such isomeric compounds; however, experimental results alone do not directly provide in-depth structural information. In this thesis, computational chemistry is first used to explain experimental results and understand the conformational preference of the gas phase ions formed from the lithiation of cis-3, cis-4 and trans-4 hydroxyproline isomers and then used in a predictive manner to evaluate IRMPD spectroscopy and IMS as potential paths …

Surface Enhanced Raman Spectroscopy (Sers) As A Nanoscale Adsorption Phenomenon: Development Of Tailored Nanomaterials For Applications In Drug Detection, Chiara Deriu

FIU Electronic Theses and Dissertations

Surface Enhanced Raman Spectroscopy (SERS) is an analytical technique in which nanostructured substrates amplify the inherently weak Raman signal of an adsorbed species by several orders of magnitude, enabling the detection of trace compounds, up to the single molecule level. While this may be an exceptional tool for any analytical scientist, SERS is at present relegated to the role of academic sensation, and is underutilized in everyday analytical practice. The SERS community is increasingly attributing this setback to a poor understanding of nanoscale surfaces and their chemical environment; since molecular adsorption at the nanostructured surface enables SERS detection, uncertainty about …

Chem 360-003: Environmental Chemistry, Alexei Khalizov

Chemistry, Environmental and Forensic Science Syllabi

No abstract provided.

Emplacement Conditions Of Magma(S) Forming Jurassic Plutonic Rocks In Gümüşhane (Eastern Pontides, Turkey), Emre Aydinçakir, Ramazan Gündüz, Cem Yücel

Bulletin of the Mineral Research and Exploration

In this study, the petrography, mineral chemistry and crystallization conditions were reported for the Alemdar and Işıkdere plutons located in limited areas in the south of the Eastern Pontides. These plutons, which trend mostly in NE-SW directions, were emplaced by cutting the Early- Middle Carboniferous-aged Gümüşhane Granitoid and Early-Middle Jurassic Şenköy formation. Petrographically, the studied plutons are compositionally fine to medium grained quartz-diorite, quartz monzodiorite and tonalite. The rocks in the plutons have granular, poikilitic, monzonitic, graphic and rare porphyritic textures with consist of plagioclase, (An05-92), hornblende (Mg# = 0.52- 0.81), biotite (Mg# = 0.32-0.67), orthoclase, quartz and Fe-Ti oxide. …

Multicourse Comparative Study Of The Core Aspects For Flipped Learning: Investigating In-Class Structure And Student Use Of Video Resources, Nicole Naibert, Emryse Geye, Michael M. Phillips, Jack Barbera

Chemistry Faculty Publications and Presentations

Since 2013, the number of publications on flipped learning within chemistry have steadily increased. However, most of these studies focus on flipped course reforms within individual institutions, while the outcomes of any learning environment are dependent on how the environment is structured and the degree to which students interact with its elements. In this study, we apply a coordinated set of assessment practices to investigate similarities among flipped chemistry courses at five institutions in the United States. All courses in the study followed the two basic tenets of flipped learning: (1) foundational information was delivered through preclass materials (PCMs), and …

Pesticide Residue Monitoring In Marketed Fresh Vegetables And Fruits In Central Taiwan (1999-2004) And An Introduction To The Haccp System, J.-M. Chang, T.-H. Chen, T.-J. Fang

Journal of Food and Drug Analysis

The objectives of this study are: (1) to collect and analyze the data of pesticide residues in vegetables and fruits in central Taiwan; (2) to compare the statistics of pesticide residues data in vegetables and fruits in 4 regions of Taiwan; and (3) to introduce the Hazard Analysis Critical Control Point (HACCP) system to industries and growers of vegetables and fruits for improving the safety of agricultural products. The 1999 samples of vegetables and fruits were collected from supermarkets and traditional markets by 6 local bureau of health in central Taiwan (1999-2004) and analyzed for the presence of 70∼79 pesticide …

Phosphorylation Of Adp-Glucose Pyrophosphorylase During Wheat Seeds Development, Danisa M. L. Ferrero, Claudia V. Piattoni, Matías D. Asencion Diez, Bruno E. Rojas, Matías D. Hartman, Miguel A. Ballicora, Alberto A. Iglesias

Chemistry: Faculty Publications and Other Works

Starch is the dominant reserve polysaccharide accumulated in the seed of grasses (like wheat). It is the most common carbohydrate in the human diet and a material applied to the bioplastics and biofuels industry. Hence, the complete understanding of starch metabolism is critical to design rational strategies to improve its allocation in plant reserve tissues. ADP-glucose pyrophosphorylase (ADP-Glc PPase) catalyzes the key (regulated) step in the synthetic starch pathway. The enzyme comprises a small (S) and a large (L) subunit forming an S2L2 heterotetramer, which is allosterically regulated by orthophosphate, fructose-6P, and 3P-glycerate. ADP-Glc PPase was found in a phosphorylated …

Investigation Of Evidence For The Internal Structure Of A Modified Science Motivation Questionnaire Ii (Msmq Ii): A Failed Attempt To Improve Instrument Functioning Across Course, Subject, And Wording Variants, Regis Komperda, Kathryn Hosbein, Michael M. Phillips, Jack Barbera

Chemistry Faculty Publications and Presentations

The Science Motivation Questionnaire II (SMQ II) was developed to measure aspects of student motivation in college-level science courses. Items on the SMQ II are structured such that the word ‘science’ can be replaced with any discipline title (e.g., chemistry) to produce a discipline-specific measure of student motivation. Since its original development as the Science Motivation Questionnaire and subsequent refinement, the SMQ II and its discipline-specific variants have been used in a number of science education studies. However, many studies have failed to produce acceptable validity evidence for their data based on the proposed internal structure of the …

Fundamental Understanding Of Plasma Discharge Formation In Liquid And Multiphase Configurations Through Multiphysics Modeling, Ali Charchi Aghdam

Theses and Dissertations

During the last two decades, non-thermal plasma discharges in and in contact with liquids have received significant attention due to their wide range of applications including chemical analysis, medical, water treatment, fuel processing, etc. Despite the tremendous interest and advances attained in the experimental studies, modeling efforts providing a comprehensive understanding of the underlying physicochemical processes are limited. There is still no unified theory on plasma formation in dense medium and various theories have been proposed such as the presence of bubbles and tunneling which are topics of debate. In the first part of this study, a mathematical model is …

Optimization And Longevity Of Functionalized Multi-Walled Carbon Nanotube-Enabled Membranes For Water Treatment, Madeleine Michael Isabella White

Master's Theses

Water scarcity is a growing concern at the global scale. Large scale water reuse is growing both in necessity and popularity. Before water reuse can be performed efficiently on a large scale or be used for potable supply, even indirectly, contaminants of emerging concern (CECs) will need to be treated at the full scale. Advanced oxidation processes (AOPs) are a form of advanced water treatment capable of treating a wide range of CECs. This study contributes to the growing field of AOPs and more specifically AOPs using ozone combined with functionalized multi-walled carbon nanotubes (MWCNTs). Ozonation of MWCNTs has been …

Silver-Catalyzed Synthesis Of Disubstituted Fluorinated Isoxazoles, Micah Stewart

Honors Theses

The presence of fluorine can provide organic compounds with useful biological properties, such as increased metabolic stability and drug uptake. Because of these advantages, fluorinated compounds make up about 30% of the drug industry. However, fluorination of complex molecules is difficult due to fluorine’s high electronegativity.

Fluorinated isoxazoles are of particular interest in the pharmaceutical industry. Isoxazoles are five-membered heterocycles with oxygen and nitrogen in the 1, 2 positions that are able to engage in interactions unavailable to other ring structures, conferring advantageous biological properties upon compounds containing them. However, there are limited synthetic routes for fluorinated isoxazoles, and those …

Measuring Meaningful Learning In A Chemistry Laboratory, Kylie Engstrom

Honors Program Theses

In the past, students in general chemistry classes at the University of Northern Iowa have struggled with pre-labs due to cognitive overload. To better prepare students for the lab portion of the class and to reduce the amount of cognitive load, professors can provide students with strategies to scaffold information for students. The CLUE General Chemistry curriculum, which emphasizes the use of scientific practices, paired with a new SWH/ADI hybrid laboratory model was implemented in one of the sections of CHEM 1110 in the Fall 2019 semester. The goal of including these new features was to provide more scaffolding for …

Zinc Finger Dna Repair Protein Targets Of Arsenite In The Nucleotide Excision Repair Pathway, Juliana M. Huestis

Biomedical Sciences ETDs

Environmental arsenic exposure affects around 100 million people worldwide. Recent evidence shows that arsenite, even at low concentrations, may act as a co-carcinogen, by displacing zinc from the zinc finger motifs of certain DNA repair proteins, leaving them vulnerable to redox modification and loss of protein function. This study probes the physical chemistry underlying arsenite and zinc binding to XPA and PARP1, in the hope of illuminating some of the aspects of protein structure that determine susceptibility to arsenite binding. In this study, dissociation constants are determined for zinc and arsenite binding to peptides corresponding to the C4 zinc finger …

Element Transport In A River-Lake Continuum Across Forest-Dominated Landscapes: A Case Study In Central Louisiana, Zhen Xu

LSU Doctoral Dissertations

Studying the biogeochemical connectivity between rivers and lakes can help us understand their ecological and environmental impacts within a drainage basin, which is especially true for forest watersheds that play a vital role in provisioning freshwater services to ecosystems and downstream communities. This dissertation research consists of three interconnected studies with the overarching goal of discerning the connectivity of elements in a river-lake continuum across forest-dominated landscapes. These studies utilized water samples and in situ measurements collected from the Little River-Catahoula Lake continuum in the subtropical Louisiana, USA at monthly intervals during 2015-2016 and 1978-2008 historical water quality, hydrological and …

The New Hampshire, Vol. 109, No. 20 (Mar. 12, 2020), The New Hampshire

The New Hampshire Print Edition

An independent student produced newspaper from the University of New Hampshire.

Assessing Differences Between Three Virtual General Chemistry Experiments And Similar Hands-On Experiments, Cory Hensen, Gosia Glinowiecka-Cox, Jack Barbera

Chemistry Faculty Publications and Presentations

To date the efficacy of virtual experiments is not well understood. To better understand what differences may exist between a hands-on learning environment and a virtual learning environment, three experiments were chosen for investigation. For each experiment, approximately half of the students completed a hands-on version of the experiment and the other half completed a virtual version. After completing the given experiment, students were compared on: their ability to meet the learning objectives for that experiment, their responses to six affective scales, and their grade on a laboratory report. Differences were found on four learning objectives. Two of these learning …

Masson Co-Authors Paper In Top-Tier Chemistry Journal On Supramolecular Self-Sorting, Ohio University College Of Arts & Sciences

All Forum Articles

No abstract provided.

Mole Street Journal, January 2020, University Of Arkansas, Fayetteville. Dept. Of Chemistry And Biochemistry

Mole Street Journal

No abstract provided.

Chem 361-002: Environmental Chemistry Ii, Alexei Khalizov

Chemistry, Environmental and Forensic Science Syllabi

No abstract provided.

Water-Mediated Peptide Bond Formation In The Gas Phase: A Model Prebiotic Reaction, George C. Shields, Ariel Gale, Tuguldur T. Odbadrakh, Tyler Ball

Chemistry Publications

The emergence of life on the prebiotic Earth must have involved the formation of polypeptides, yet the polymerization of amino acids is thermodynamically unfavorable under biologically relevant aqueous conditions because amino acids are zwitterions in solution and because of the production of a water molecule through a condensation reaction. Many mechanisms for overcoming this thermodynamic unfavorability have been proposed, but the role of gas phase water clusters has not been investigated. We present the thermodynamics of the water-mediated gas phase dimerization reaction of glycine as a model for the atmospheric polymerization of amino acids prior to the emergence of biological …

Department Of Chemistry (University Of Maine) Records, Special Collections, Raymond H. Fogler Library, University Of Maine

Finding Aids

The University of Maine Department of Chemistry offers both undergraduate and graduate programs in chemistry, including a Ph.D. program, the establishment of which is documented in these records. The Department is housed in Aubert Hall which was constructed in 1914 and named in honor of the first University of Maine chemistry professor, Professor Albert Aubert, who came to the University of Maine in 1874, and departed in 1909.

The majority of the records were created during the tenures of John William Beamesderfer (1952-1964) and James Langdon Wolfhagen (1964-1976) as chairs of the Department of Chemistry. There is also material from …

Hierarchical Hybrid Materials From Flexible Fabric Substrates, Wenhu Wang

Browse all Theses and Dissertations

The goal of this project is to investigate fabrication approaches and structure-property relationships of porous and flexible hierarchical hybrid solids suitable for advanced surface-active devices. Multi-scale hierarchical carbon materials are being fabricated by strong covalent attachment of multiwall carbon nanotube(MWCNTs) arrays on flexible carbon fabric substrates in order to enhance the surface area per unit volume. This was done using chemical vapor deposition (CVD) after functionalizing the surface with a plasma-derived nano-oxide coating. Structural and chemical characterization is performed using scanning electron microscope(SEM), energy dispersive spectroscopy(EDS) and x-ray photoelectron spectroscopy(XPS). Surface area estimates have been made by building structural models …

Implementing And Assessing The Use Of A New Strategy For Training Chemistry Graduate Teaching Assistants, Amanda Hyett

Electronic Theses and Dissertations

Graduate teaching assistants (GTAs) largely contribute to undergraduate education but are often underprepared for their role as educators. Most graduate students attend graduate school to perform research and are then asked to teach for the first time without sufficient pedagogy training. To assist in increasing the GTAs pedagogical knowledge, a scenario-based activity series was developed and implemented for first- and second-year GTAs. Developing scenario-based scenarios from actual laboratory events provided GTAs with the opportunity to practice prior to engaging in the laboratory classroom. The Teaching Assistant Intervention Activities (TAIAs) included topics such as interpersonal skills and behaviors, group process, working …

Technology-Based Culturally Relevant Chemistry Education (Crce), Mercy Adoma Fosu

Electronic Theses and Dissertations

The relevance of chemistry concepts and principles remains a challenge for most students enrolled in college chemistry courses. Part of this problem is the disconnect with what students experience in their every-day lives, and how the material, specifically chemistry content is presented via textbooks, lectures, and laboratory teaching. Moreover, the teaching of general chemistry has traditionally focused on traditional, instructor-centric expository delivery of course materials, that treats students as empty vessels devoid of prior knowledge. Students prior knowledge and experiences are crucial in shaping their understanding of scientific concepts and principles. Even students with relatively low expectations for success in …

Route Exploration And Synthesis Of The Reported Pyridone-Based Pdi Inhibitor Stk076545, Eric Greve, Sergey Lindeman, Christina Scartelli, Lin Lin, Robert Flaumenhaft, Chris Dockendorff

Chemistry Faculty Research and Publications

The enzyme protein disulfide isomerase (PDI) is essential for the correct folding of proteins and the activation of certain cell surface receptors, and is a promising target for the treatment of cancer and thrombotic conditions. A previous high-throughput screen identified the commercial compound STK076545 as a promising PDI inhibitor. To confirm its activity and support further biological studies, a resynthesis was pursued of the reported β-keto-amide with an N-alkylated pyridone at the α-position. Numerous conventional approaches were complicated by undesired fragmentations or rearrangements. However, a successful 5-step synthetic route was achieved using an aldol reaction with an α-pyridone allyl …

Alternatives To Red Blood Cell Transfusions, Julia Prosser

Capstone Showcase

Abstract

Introduction: Allogenic red blood cell (RBC) transfusions are used for a number of different reasons. As with any medical procedure, allogenic RBC transfusions are not risk-free. Since the first recorded blood transfusion in 1655, the process has remained relatively unchanged. ABO incompatibility and contamination with infectious diseases are two major complications associated with RBC transfusions. Furthermore, traditional allogenic RBC transfusions have supply and demand issues. These issues, plus several more, could be alleviated with the use of artificial blood. This paper addresses the important clinical question: In patients who require RBC transfusions (P), is there a viable artificial blood …

Use Of Otolith Chemistry To Assess Recruitment And Habitat Use Of A White Bass Fishery In A Nebraska Reservoir, Matthew A. Perrion, Mark A. Kaemingk, Keith D. Koupal, Casey W. Schoenebeck, Nate A. Bickford

Nebraska Cooperative Fish and Wildlife Research Unit: Staff Publications

Managing fisheries that exhibit variable annual recruitment is challenging, and maintenance stockings are often prescribed to minimize interannual population variation. Maintenance stockings are costly and may not be necessary if sufficient natural recruitment is occurring. Therefore, developing tools and techniques that can collectively assess hatching origin and subsequent habitat use of individuals would be valuable. Herein, we aimed to assess the efficacy of otolith chemistry techniques to (1) determine whether there was evidence of natural recruitment within an annually stocked white bass population and (2) examine the potential to describe spatial reservoir use of these age-0 fish. A sample of …

Optimization Of E-Textiles For Lactic Acid Detection, Andrew Laboy, Mallory David

Williams Honors College, Honors Research Projects

The overall goal of the project is to develop an e-textile that will be able to determine different characteristics of an athlete's health through multiple sensors. The goal of these sensors is to monitor physiological parameters for health and fitness uses in real time. Building from the existing sodium concentration sensor, these new sensors will detect lactate levels within sweat to monitor instantaneous health which allows customization of workout and overall health regimen.