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Open Access. Powered by Scholars. Published by Universities.®

2019

Western Kentucky University

Health and Physical Education

IMCL

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A Family History Of Type 2 Diabetes Does Not Impact Skeletal Muscle Lipid Content, Jasmin Jenkins, Sudip Bajpeyi Feb 2019

A Family History Of Type 2 Diabetes Does Not Impact Skeletal Muscle Lipid Content, Jasmin Jenkins, Sudip Bajpeyi

International Journal of Exercise Science: Conference Proceedings

A high intramyocellular lipid (IMCL) has been associated not only with insulin resistance, obesity, and type 2 diabetes; but also in insulin sensitive endurance trained athletes – known as “athlete’s paradox”. A family history of type 2 diabetes (FH+) has been shown as a risk factor for the development of insulin resistance and type 2 diabetes (T2D). However, it is unclear whether a FH+ affects IMCL content and exercise induced changes in IMCL when compared to those without a family history of type 2 diabetes (FH-). PURPOSE: The purpose of this study were 1) to compare IMCL content between …


Exercise Leads To Increase In Smaller Lipid Droplet Morphology In Peripheral Region Of Muscle Fiber, Victoria Rosas Feb 2019

Exercise Leads To Increase In Smaller Lipid Droplet Morphology In Peripheral Region Of Muscle Fiber, Victoria Rosas

International Journal of Exercise Science: Conference Proceedings

In a previous study, we have shown that high fat overfeeding results in decreased smaller lipid droplet density in the peripheral region of skeletal muscle fiber. This decrease was associated with high fat overfeeding induced weight gain and insulin resistance. However, it is not clear whether an acute bout of exercise (elevated fat oxidation state) affects lipid droplet size. PURPOSE: To determine the effects of a single bout of endurance exercise on skeletal muscle lipid content and lipid droplet size. METHODS: Ten healthy male volunteers (Mean ± SEM; age: 23.11 ± 0.98; BMI: 23.27 ± 0.50 kg/m2) participated …