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2019

Western Kentucky University

Health and Physical Education

Exercise

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Exercise Participation And Indicators Of Skeletal Muscle Health In Women With Hypothyroidism, Ryan A. Gordon, Gena D. Guerin, Emily L. Zumbro, Ann O. Amuta, Anthony A. Duplanty Feb 2019

Exercise Participation And Indicators Of Skeletal Muscle Health In Women With Hypothyroidism, Ryan A. Gordon, Gena D. Guerin, Emily L. Zumbro, Ann O. Amuta, Anthony A. Duplanty

International Journal of Exercise Science: Conference Proceedings

Women with hypothyroidism report undesirable skeletal muscle symptoms at rest and during exercise. The severity of skeletal muscle symptoms may influence an individual’s willingness and capacity to exercise. PURPOSE: This study aimed to determine the relationship between exercise and skeletal muscle symptoms at rest and during exercise in women with hypothyroidism. METHODS: An online survey was completed by female participants diagnosed with hypothyroidism currently undergoing prescribed thyroid hormone treatment (n=580). Participants responded to questions related to basal muscle symptoms (MS), and muscle pain (MP) and fatigue (MF) experienced during exercise. Participants reported the type of exercise they performed, …


Exercise Cerebral Blood Flow Hemodynamics Differ In Hot Dry And Humid Conditions, Julianna J. Kilpatrick, Paolo Miguel Salvador, Kyleigh Allie, Eric Rivas Feb 2019

Exercise Cerebral Blood Flow Hemodynamics Differ In Hot Dry And Humid Conditions, Julianna J. Kilpatrick, Paolo Miguel Salvador, Kyleigh Allie, Eric Rivas

International Journal of Exercise Science: Conference Proceedings

Passive and exercise-heat stress have been reported to cause reductions in cerebral blood flow (CBF); however, it is unknown if CBF velocity is different under hot dry and humid conditions. PURPOSE: This project tested the hypothesis that upright rest and exercise-heat stress in hot dry and humid conditions result in similar CBF reductions. METHODS: Seven healthy active (7 day activity: 9887±3564 steps/day; VO2max: 52±10 mL/kg/min) subjects (5M/2F, 24±9y, 171±6cm, 68±7kg) completed a 30 min baseline rest followed by 60 min of exercise at a rate of perceived exertion (RPE) of 12 (between light and somewhat hard) on a …


A Family History Of Type 2 Diabetes Does Not Impact Skeletal Muscle Lipid Content, Jasmin Jenkins, Sudip Bajpeyi Feb 2019

A Family History Of Type 2 Diabetes Does Not Impact Skeletal Muscle Lipid Content, Jasmin Jenkins, Sudip Bajpeyi

International Journal of Exercise Science: Conference Proceedings

A high intramyocellular lipid (IMCL) has been associated not only with insulin resistance, obesity, and type 2 diabetes; but also in insulin sensitive endurance trained athletes – known as “athlete’s paradox”. A family history of type 2 diabetes (FH+) has been shown as a risk factor for the development of insulin resistance and type 2 diabetes (T2D). However, it is unclear whether a FH+ affects IMCL content and exercise induced changes in IMCL when compared to those without a family history of type 2 diabetes (FH-). PURPOSE: The purpose of this study were 1) to compare IMCL content between …


The Effects Of A Single Bout Of Endurance Exercise On Glucose Transporter-4 (Glut-4) Content, Manuel Gomez, Sudip Bajpeyi Feb 2019

The Effects Of A Single Bout Of Endurance Exercise On Glucose Transporter-4 (Glut-4) Content, Manuel Gomez, Sudip Bajpeyi

International Journal of Exercise Science: Conference Proceedings

Glucose Transporter protein-4 (GLUT-4) is considered the predominant glucose transporter in skeletal muscle. Exercise has been shown to increase glucose uptake and GLUT-4 protein content in skeletal muscle following muscle contraction. PURPOSE: To determine the acute effects of a single bout of moderate intensity endurance exercise on skeletal muscle GLUT-4 content. METHODS: 10 healthy male volunteers (age: 24.4 ± 1.3 years; BMI 23.16 ± 0.60 kg/m²) participated in a single bout of endurance exercise on a cycle ergometer at 65% maximal aerobic capacity (VO2max) for 1.5 – 2.0 hours (650kcal). Muscle biopsies were obtained from the vastus …


Exercise Leads To Increase In Smaller Lipid Droplet Morphology In Peripheral Region Of Muscle Fiber, Victoria Rosas Feb 2019

Exercise Leads To Increase In Smaller Lipid Droplet Morphology In Peripheral Region Of Muscle Fiber, Victoria Rosas

International Journal of Exercise Science: Conference Proceedings

In a previous study, we have shown that high fat overfeeding results in decreased smaller lipid droplet density in the peripheral region of skeletal muscle fiber. This decrease was associated with high fat overfeeding induced weight gain and insulin resistance. However, it is not clear whether an acute bout of exercise (elevated fat oxidation state) affects lipid droplet size. PURPOSE: To determine the effects of a single bout of endurance exercise on skeletal muscle lipid content and lipid droplet size. METHODS: Ten healthy male volunteers (Mean ± SEM; age: 23.11 ± 0.98; BMI: 23.27 ± 0.50 kg/m2) participated …


Skin Temperature And High Dew Point In Hot Environments Affects Self-Paced Exercise, Paolo Miguel Salvador, Julianna Kilpatrick, Kyleigh Allie, Eric Rivas Feb 2019

Skin Temperature And High Dew Point In Hot Environments Affects Self-Paced Exercise, Paolo Miguel Salvador, Julianna Kilpatrick, Kyleigh Allie, Eric Rivas

International Journal of Exercise Science: Conference Proceedings

Dew point (dp) is the absolute measure of water vapor and directly affects comfort whereas 5-10℃ feels dry; 10-15℃ feels comfortable and 20-24℃ feels uncomfortable. PURPOSE: This project tested the hypothesis that exercise in hot ambient conditions with a high dp (>20℃) would affect the selection of self-paced exercise compared to neutral dry conditions (dp). METHODS: Six healthy active (7 day activity: 9826±3900 steps/day; VO2max: 52±10 mL/kg/min ) subjects (4M/2F, 25±9y, 171±6cm, 69±7kg) completed a 30 min baseline rest then 60 min of exercise intensity they chose that represents their perceived exertion of 12 …


Inflammation-Associated Rna Signaling Is Reduced Following A Half-Marathon Race When Supplemented With Curcumin And A Pomegranate Extract, Elizabeth A. Tanner, Melody A. Gary, Asheal A. Davis, Brian K. Mcfarlin Feb 2019

Inflammation-Associated Rna Signaling Is Reduced Following A Half-Marathon Race When Supplemented With Curcumin And A Pomegranate Extract, Elizabeth A. Tanner, Melody A. Gary, Asheal A. Davis, Brian K. Mcfarlin

International Journal of Exercise Science: Conference Proceedings

Prolonged endurance exercise performances provide a unique model for investigating the combined effects of oxidative stress and eccentric muscle contraction on differential gene expression with nutritional interventions known to blunt inflammation. Dietary polyphenols (i.e. curcumin, pomegranate, etc.) have been shown to reduce exercise-induced inflammation associated mRNA and protein expression with fewer side effects than NSAIDs. PURPOSE: To investigate the effect of combined curcumin (500-1000 mg/d; Longvida®) and pomegranate extract (500-1000 mg/d; Pomella®) supplement for 30-days on mRNA expression following a half marathon race. METHODS: All protocols were approved by the University IRB committee and participants gave written informed consent. Participants …


Using Dietary Polyphenols To Manage Post Exercise Inflammation, Melody A. Gary, Elizabeth A. Tanner, Brian K. Mcfarlin, Asheal A. Davis Feb 2019

Using Dietary Polyphenols To Manage Post Exercise Inflammation, Melody A. Gary, Elizabeth A. Tanner, Brian K. Mcfarlin, Asheal A. Davis

International Journal of Exercise Science: Conference Proceedings

Individuals participating in prolonged exercise sessions and associated training experience regular inflammation and muscle soreness. Natural products with known anti-inflammatory and/or oxidative stress blocking effects represent attractive options to traditional NSAID treatments. PURPOSE: To investigate the effect of combined curcumin (500-1000 mg/d; Longvida®), pomegranate extract (500-1000 mg/d; Pomella®), and Methylsulfonylmethane (500-1000 mg/d; OptiMSM®) supplement for 30-days on protein inflammatory biomarkers, inflammation-associated RNA, and oxidative. METHODS: All protocols were approved by the University IRB committee and participants gave written informed consent. Subjects were supplemented for 30-d prior to the half marathon race. Venous blood samples were collected for serum or RNA …


Circulating Inflammatory And Oxidative Stress Responses To Steady-State Moderate-Intensity And High-Intensity Interval Exercise In Mid-Spectrum Chronic Kidney Disease, Matthew Peterson, Jeffrey S. Forsse, James K. Taylor, Zach Papadakis, Nick Schwedock, Burritt Hess, Jackson O. Griggs Md, Crawford Allison, Ron Wilson Md, Kathleen Adair, Mitch Cholewinski, Peter Grandjean Feb 2019

Circulating Inflammatory And Oxidative Stress Responses To Steady-State Moderate-Intensity And High-Intensity Interval Exercise In Mid-Spectrum Chronic Kidney Disease, Matthew Peterson, Jeffrey S. Forsse, James K. Taylor, Zach Papadakis, Nick Schwedock, Burritt Hess, Jackson O. Griggs Md, Crawford Allison, Ron Wilson Md, Kathleen Adair, Mitch Cholewinski, Peter Grandjean

International Journal of Exercise Science: Conference Proceedings

Inflammation and oxidative stress can be potent modulators of vascular function. These factors may transiently respond to moderate-intensity steady state exercise (SSE) in a manner that improves post-exercise vascular function in healthy adults. Whether exercise imparts similar effects in adults with Stage 3 or 4 chronic kidney disease (CKD) remains understudied. Moreover, a comparison of SSE and high-intensity interval exercise (HIIE) may add to clinically-relevant findings for improving vascular function in mid-spectrum CKD. PURPOSE: To determine the influence of SSE and a comparable amount of HIIE on post-exercise inflammation and oxidative stress in patients diagnosed with secondary Stage 3 or …


Renal Function Responses To Steady-State Moderate-Intensity And High-Intensity Interval Exercise In Mid-Spectrum Chronic Kidney Disease, Kathleen E. Adair, Jeffrey S. Forsse 4681817, Matthew Peterson, Zacharias Papadakis, Mitch Cholewinski, Peter Grandjean Feb 2019

Renal Function Responses To Steady-State Moderate-Intensity And High-Intensity Interval Exercise In Mid-Spectrum Chronic Kidney Disease, Kathleen E. Adair, Jeffrey S. Forsse 4681817, Matthew Peterson, Zacharias Papadakis, Mitch Cholewinski, Peter Grandjean

International Journal of Exercise Science: Conference Proceedings

Efficacy of exercise to improve renal function remains understudied in adults with mid-spectrum chronic kidney disease (CKD). In addition, a comparison of steady-state exercise (SSE) and high-intensity interval exercise (HIIE) may contribute clinically-relevant information for exercise-related augmentation of renal function in mid-spectrum CKD. PURPOSE: To determine the influence of SSE and a comparable amount of HIIE on indicators of post-exercise renal function in patients diagnosed with secondary Stage 3 or 4 CKD. METHODS: Twenty participants (n = 6 men; n = 14 women; age 62.0 + 9.9 yr; weight 80.9 + 16.2 kg; body fat 37.3 + 8.5% …