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2011

Cognition

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Hallucination Proneness, Schizotypy And Meta-Cognition, John Stirling, Emma Barkus, Shon Lewis Dec 2011

Hallucination Proneness, Schizotypy And Meta-Cognition, John Stirling, Emma Barkus, Shon Lewis

Emma Barkus

Disordered or maladaptive meta-cognitive processing appears to be a prominent feature for some individuals with a diagnosis of schizophrenia. We sought to establish whether healthy individuals distinguished either in terms hallucination proneness (HP) or level of schizotypy could also be differentiated on the sub-scales of the Meta-cognitions Questionnaire (MCQ), or a modified version of it in which items about worry were replaced with items specifically related to thinking. A total of 106 healthy volunteers completed the Oxford and Liverpool Inventory of Feelings and Experiences and Launay-Slade hallucination scale, the Schizotypal Personality Questionnaire and two versions of the MCQ: the original …


Research Participation By Older Adults At End Of Life: Barriers And Solutions, Melissa Lehan Mackin, Keela Herr, K. Bergen-Jackson, P. Fine, C. Forcucci, S. Sanders Dec 2011

Research Participation By Older Adults At End Of Life: Barriers And Solutions, Melissa Lehan Mackin, Keela Herr, K. Bergen-Jackson, P. Fine, C. Forcucci, S. Sanders

Melissa Lehan Mackin

The purpose of this article is to elaborate on barriers to research participation by older adults at end of life. We focus on the hospice setting and classify barriers to research participation into six domains: societal attitudes toward death, research procedures, health care organizations, agency staff, patients' families and caregivers, and patient characteristics. We characterize particular participation issues, uncertainties in participation for individuals with advanced illness, and infringements on patient self-determination, as well as potential solutions to these research challenges. Our observation of the complex palliative context includes the realization that a singular change will not have large enough impact …


Visual Attention To Erotic Stimuli In Androphilic Male-To-Female Transsexuals, Sarah A. Akhter Dec 2011

Visual Attention To Erotic Stimuli In Androphilic Male-To-Female Transsexuals, Sarah A. Akhter

UNLV Theses, Dissertations, Professional Papers, and Capstones

The present study investigated sex differences in visual attention to erotic stimuli by comparing three groups of individuals: heterosexual men, heterosexual women, and androphilic MtF transsexuals. Twenty men, 20 women and 13 MtF transsexuals were shown 10 split-screen slides, each featuring one nude erotic photo of a man shown on half of the screen and one nude erotic photo of a woman shown on the other half of the screen. Eye movements were tracked as participants viewed the slides. All participants were heterosexual (Kinsey 0-1) relative to gender identity, thus erotic targets for natal men were nude women in the …


Revisiting Austin V. Loral: A Study In Economic Duress, Contract Modification And Framing, Meredith R. Miller Nov 2011

Revisiting Austin V. Loral: A Study In Economic Duress, Contract Modification And Framing, Meredith R. Miller

Meredith R. Miller

Austin v. Loral, 29 N.Y.2d 124 (1971), is a favorite among Contracts casebooks because the New York Court of Appeals held that it was a "classic" example of economic duress. It involved Austin, a small gear part manufacturer, who had entered into a subcontract to provide gear parts to Loral, a publicly-traded defense industry supplier. Loral had a contract with the U.S. government to supply radar sets, to be used in the U.S. efforts in Vietnam. Midway through performance of the subcontract, Austin apparently refused to continue to deliver the gear parts unless Loral acceded to certain demands, which included …


Alzheimer's Residents' Cognitive And Functional Measures: Special And Traditional Care Unit Comparison, Elizabeth Swanson, Meridean Maas, Kathleen Buckwalter Nov 2011

Alzheimer's Residents' Cognitive And Functional Measures: Special And Traditional Care Unit Comparison, Elizabeth Swanson, Meridean Maas, Kathleen Buckwalter

Elizabeth A. Swanson

The aim of this field experiment was to compare the effects of a special care unit (SCU) on residents with Alzheimer's disease (AD) who lived on the SCU and on traditional (integrated) nursing home units. Twenty-two subjects, 13 on the SCU and 9 on traditional integrated units were compared. Repeated measures ANOVA was used to assess differences between the two groups and within the groups over two bimonthly pretests and two bimonthly posttests. No significant differences on cognitive or functional abilities scores were evident for the groups and no significant differences were found over time. However, consistent with the prediction …


Cognitive Bias Modification: Past Perspectives, Current Findings, And Future Applications, Paula T. Hertel, A. Mathews Nov 2011

Cognitive Bias Modification: Past Perspectives, Current Findings, And Future Applications, Paula T. Hertel, A. Mathews

Psychology Faculty Research

Research conducted within the general paradigm of Cognitive Bias Modification (CBM) reveals that emotional biases in attention, interpretation, and memory are not merely associated with emotional disorders but contribute to them. After briefly describing research on both emotional biases and their modification, we examine similarities between CBM paradigms and older experimental paradigms used in research on learning and memory. We also compare the techniques and goals of CBM research to other approaches to understanding cognition/emotion interactions. From a functional perspective, the CBM tradition reminds us to use experimental tools to evaluate assumptions about clinical phenomena and more generally, about causal …


The Science Of Learning, Geoff Masters Nov 2011

The Science Of Learning, Geoff Masters

Research Developments

Geoff Masters explains how an emerging field of research called the science of learning is improving our understanding of how students learn.


Elevated Stearoyl-Coa Desaturase In Brains Of Patients With Alzheimer's Disease, Giuseppe Astarita, Kwang-Mook Jung, Vitaly Vasilevko, Nicholas V. Dipatrizio, Sarah K. Martin, David H. Cribbs, Elizabeth Head, Carl W. Cotman, Daniele Piomelli Oct 2011

Elevated Stearoyl-Coa Desaturase In Brains Of Patients With Alzheimer's Disease, Giuseppe Astarita, Kwang-Mook Jung, Vitaly Vasilevko, Nicholas V. Dipatrizio, Sarah K. Martin, David H. Cribbs, Elizabeth Head, Carl W. Cotman, Daniele Piomelli

Sanders-Brown Center on Aging Faculty Publications

The molecular bases of Alzheimer's disease (AD) remain unclear. We used a lipidomic approach to identify lipid abnormalities in the brains of subjects with AD (N = 37) compared to age-matched controls (N = 17). The analyses revealed statistically detectable elevations in levels of non-esterified monounsaturated fatty acids (MUFAs) and mead acid (20:3n-9) in mid-frontal cortex, temporal cortex and hippocampus of AD patients. Further studies showed that brain mRNAs encoding for isoforms of the rate-limiting enzyme in MUFAs biosynthesis, stearoyl-CoA desaturase (SCD-1, SCD-5a and SCD-5b), were elevated in subjects with AD. The monounsaturated/saturated fatty acid ratio ('desaturation index')--displayed a strong …


The Early Bird Does Not Get The Worm: Time-Of-Day Effects On College Students' Basic Cognitive Processing, P. Allen, J. Grabbe, Ann Mccarthy, A. Bush, B. Wallace Oct 2011

The Early Bird Does Not Get The Worm: Time-Of-Day Effects On College Students' Basic Cognitive Processing, P. Allen, J. Grabbe, Ann Mccarthy, A. Bush, B. Wallace

Ann Marie McCarthy

We conducted a neuropsychological and cognitive assessment study to determine whether time of day affects cognitive performance. We measured executive control (fluency), processing speed, semantic memory, and episodic memory performance. We followed 56 students across 3 different times of day, testing performance on vocabulary, fluency, processing speed, and episodic memory. Results showed an advantage for fluency and digit symbol task performance in the afternoon and evening testing times relative to morning testing (regardless of testing order), but that time of day did not affect semantic or episodic memory performance. These results suggest that optimal executive functioning and processing speed may …


Imagination Column. Creative Realitying: Hozho... Bringing Forth A World... And Mutual Process, Howard Butcher Oct 2011

Imagination Column. Creative Realitying: Hozho... Bringing Forth A World... And Mutual Process, Howard Butcher

Howard K. Butcher

No abstract provided.


Fifth-Grade Students' Tactical Understanding, Decision-Making And Transfer Of Knowledge In A Tactical Games Model Net/Wall Sampling Unit, Heidi Renee Bohler Sep 2011

Fifth-Grade Students' Tactical Understanding, Decision-Making And Transfer Of Knowledge In A Tactical Games Model Net/Wall Sampling Unit, Heidi Renee Bohler

Open Access Dissertations

The Tactical Games Model (TGM) is an instructional model in which the primary assumption is to facilitate students' tactical understanding of games (i.e., response-selection and execution processes). Additionally, there is speculation that tactical understanding of one game transfers to other tactically similar games (Mitchell, Oslin & Griffin, 2006, p. 20). Limited research has been conducted regarding student response selection processes, problem representations, knowledge base development, or transfer of learning in this model. Griffin and Patton (2005) called for examination of TGM through an information processing lens. Examining action, condition, and goal responses of novice physical education students could provide significant …


Cerebral Lateralization Determines Hand Preferences In Australian Parrots, Culum Brown, Maria Magat Aug 2011

Cerebral Lateralization Determines Hand Preferences In Australian Parrots, Culum Brown, Maria Magat

Sentience Collection

Individual preference for the use of one limb over the other to explore the environment or manipulate objects is common trait among vertebrates. Here, we explore the hypothesis that limb preference is determined by the engagement of a particular cerebral hemisphere to analyse certain stimuli. We recorded the eye and foot preferences of 322 individuals from 16 species of Australian parrots while investigating potential food items. Across all species, eye preferences explained 99 per cent of the variation in foot use in Australian parrots. The vast majority of species showed significant relationships between eye and foot preferences at the population …


Neural Correlates Of Attention Bias In Posttraumatic Stress Disorder: A Fmri Study, Negar Fani Aug 2011

Neural Correlates Of Attention Bias In Posttraumatic Stress Disorder: A Fmri Study, Negar Fani

Psychology Dissertations

Attention biases to trauma-related information contribute to symptom maintenance in Posttraumatic Stress Disorder (PTSD); this phenomenon has been observed through various behavioral studies, although findings from studies using a precise, direct bias task, the dot probe, have been mixed. PTSD neuroimaging studies have indicated atypical function in specific brain regions involved with attention bias; when viewing emotionally-salient cues or engaging in tasks that require attention, individuals with PTSD have demonstrated altered activity in brain regions implicated in cognitive control and attention allocation, including the medial prefrontal cortex (mPFC), dorsolateral prefrontal cortex (dlPFC) and amygdala. However, remarkably few PTSD neuroimaging studies …


The Effect Of Endpoint Knowledge On Dot Enumeration, Alex Michael Moore Aug 2011

The Effect Of Endpoint Knowledge On Dot Enumeration, Alex Michael Moore

UNLV Theses, Dissertations, Professional Papers, and Capstones

This study attempts to extend the principle tenets of the Overlapping Waves Theory (Siegler, 1996), a framework designed to explain the progression of trends in cognitive development, to adult participants’ performance in a dot enumeration task. Literature in the 0-100 number line estimation task (Siegler & Booth, 2004, Ashcraft & Moore, 2011) has revealed a pervasive trend in child estimation such that young children (especially those in kindergarten) respond with a logarithmic line of best fit, while children at the third grade and above overwhelmingly respond with linear estimates to this same range of numbers. A similar developmental trend is …


Does Physical Activity Influence Semantic Memory Activation In Amnestic Mild Cognitive Impairment?, J. Carson Smith, Kristy A. Nielson, John L. Woodard, Michael Seidenberg, Matthew D. Verber, Sally Durgerian, Piero Antuono, Alissa M. Butts, Nathan C. Hantke, Melissa A. Lancaster, Stephen M. Rao Jul 2011

Does Physical Activity Influence Semantic Memory Activation In Amnestic Mild Cognitive Impairment?, J. Carson Smith, Kristy A. Nielson, John L. Woodard, Michael Seidenberg, Matthew D. Verber, Sally Durgerian, Piero Antuono, Alissa M. Butts, Nathan C. Hantke, Melissa A. Lancaster, Stephen M. Rao

Psychology Faculty Research and Publications

The effect of physical activity (PA) on functional brain activation for semantic memory in amnestic mild cognitive impairment (aMCI) was examined using event-related functional magnetic resonance imaging during fame discrimination. Significantly greater semantic memory activation occurred in the left caudate of High- versus Low-PA patients, (P=0.03), suggesting PA may enhance memory-related caudate activation in aMCI.


Persistence Of Unsafe Practice In Everyday Work: An Exploration Of Organizational And Psychological Factors Constraining Safety In The Operating Room, S. Espin, Lorelei Lingard, G. Baker, G. Regehr Jun 2011

Persistence Of Unsafe Practice In Everyday Work: An Exploration Of Organizational And Psychological Factors Constraining Safety In The Operating Room, S. Espin, Lorelei Lingard, G. Baker, G. Regehr

Lorelei Lingard

This paper explores the factors that influence the persistence of unsafe practice in an interprofessional team setting in health care, towards the development of a descriptive theoretical model for analyzing problematic practice routines. Using data collected during a mixed method interview study of 28 members of an operating room team, participants' approaches to unsafe practice were analyzed using the following three theoretical models from organizational and cognitive psychology: Reason's theory of "vulnerable system syndrome", Tucker and Edmondson's concept of first and second order problem solving, and Amalberti's model of practice migration. These three theoretical approaches provide a critical insight into …


Psychostimulants As Cognitive Enhancers: The Prefrontal Cortex, Catecholamines And Attention Deficit Hyperactivity Disorder, Craig Berridge, David M. Devilbiss Jun 2011

Psychostimulants As Cognitive Enhancers: The Prefrontal Cortex, Catecholamines And Attention Deficit Hyperactivity Disorder, Craig Berridge, David M. Devilbiss

Rowan-Virtua School of Osteopathic Medicine Faculty Scholarship

Psychostimulants exert behavioral-calming and cognition-enhancing actions in the treatment of attention deficit hyperactivity disorder (ADHD). Contrary to early views, extensive research demonstrates that these actions are not unique to ADHD. Specifically, when administered at low and clinically-relevant doses, psychostimulants improve a variety of behavioral and cognitive processes dependent on the prefrontal cortex (PFC) in subjects with and without ADHD. Despite the longstanding clinical use of these drugs, the neural mechanisms underlying their cognition-enhancing/therapeutic actions have only recently begun to be examined. At behaviorally-activating doses, psychostimulants produce large and widespread increases in extracellular levels of brain catecholamines. In contrast, cognition-enhancing doses …


Neuropsychological And Neurophysiological Effects Of Low-Intensity Strengthening Exercise On Cognition, Vadim V. Yerokhin Jun 2011

Neuropsychological And Neurophysiological Effects Of Low-Intensity Strengthening Exercise On Cognition, Vadim V. Yerokhin

Honors Theses

With the growing aging population, it’s becoming increasingly important to find ways to either deter or prevent dementia. To date, most research has concentrated on the effects of aerobic exercise on cognition. Unfortunately, a large portion of older adults are often contraindicated to perform aerobic exercise due to different risk factors, which increase with age. Alas, alternate ways of exercise are necessary. Low-intensity strengthening exercise is a type of exercise aimed at improving balance and strengthening muscles without requiring one to overstrain. The current 11-week long exercise study test neuropsychological effects of exercise with a neuropsychological battery and neurophysiological effects …


Electrophysiological Indices Of Aesthetically Stimulated Processes In Art-Experienced Individuals As Compared To Art-Naïve Individuals, Katharine E. Hartnack Jun 2011

Electrophysiological Indices Of Aesthetically Stimulated Processes In Art-Experienced Individuals As Compared To Art-Naïve Individuals, Katharine E. Hartnack

Honors Theses

Aesthetic judgment processes were investigated in art-experienced and art-naïve individuals. Previous electrophysiological data suggest that aesthetic judgment is a two-stage process (Hofel & Jacobson, 2007). The first stage of aesthetic judgment is impression formation which is not spontaneous, and is reflected by an early Event Related Potential (ERP) frontocentral deflection. The second stage reflected by a lateralized late ERP positivity, evaluative categorization is also not spontaneous. Participants in the current study were instructed to either simply view black and white geometric patterns or were instructed to contemplate the beauty of the patterns. Results suggest that aesthetically stimulated processes differ between …


Evolution, Cognition And Argumentation, Cristian Santibanez Yanez, Michael A. Gilbert May 2011

Evolution, Cognition And Argumentation, Cristian Santibanez Yanez, Michael A. Gilbert

OSSA Conference Archive

Sperber and Mercier (2009, 2010) maintain that argumentation is a meta-representational module. In their evolutionary view of argumentation, the function of this module would be to regulate the flow of information between interlocutors through persuasiveness on the side of the communicator and epistemic vigilance on the side of the audience. The aim of this paper is to discuss this definition of argumen-tation by analyzing what they mean by “communicator’s persuasiveness” and “audience epistemic vigilance”


‘Cognitive Systemic Dichotomization’ In Public Argumentation And Controversies, Marcelo Dascal, Amnon Knoll, Daniel Cohen May 2011

‘Cognitive Systemic Dichotomization’ In Public Argumentation And Controversies, Marcelo Dascal, Amnon Knoll, Daniel Cohen

OSSA Conference Archive

We describe and analyze an important cognitive obstacle in inter- and intra-community ar-gumentation processes, which we propose to call 'Cognitive Systemic Dichotomization' (CSD). This social phenomenon consists in the collective use of shared cognitive patterns based upon dichotomous schemati-zation of knowledge, values, and affection. We discuss the formative role of CSD on a community’s collec-tive cognition, identity, and public discourse, as well as the challenges it raises to reasoned argumentation, and how different approaches to argumentation undertake to face this obstacle to the reasonable debate of issues of public concern.


Cognition And Literary Ethical Criticism, Gilbert Plumer, Louis Groarke May 2011

Cognition And Literary Ethical Criticism, Gilbert Plumer, Louis Groarke

OSSA Conference Archive

“Ethical criticism” is an approach to literary studies that holds that reading certain carefully selected novels can make us ethically better people, e.g., by stimulating our sympathetic imagination (Nussbaum). I will try to show that this nonargumentative approach cheapens the persuasive force of novels and that its inherent bias and censorship undercuts what is perhaps the principal value and defense of the novel—that reading novels can be critical to one’s learning how to think.


Executive Function Profiles In Pediatric Traumatic Brain Injury, Erik Nelson Ringdahl May 2011

Executive Function Profiles In Pediatric Traumatic Brain Injury, Erik Nelson Ringdahl

UNLV Theses, Dissertations, Professional Papers, and Capstones

Traumatic brain injury is a common cause of disability and death among children in the United States. Insult to the frontal and temporal lobes are frequent in closed head brain injury. Cognitive deficits in a variety of domains are common sequelae of brain trauma. In many cases, trauma to the frontal and temporal lobe regions engender prominent deficits in higher-order cognitive processing, memory, and attention.

Higher-order cognitive processing, or Executive Functions are the grouping of cognitive processes necessary for organization of thoughts and activities, attending to the activities, prioritizing tasks, managing time efficiently, and making decisions (Alvarez & Emory, 2006; …


Illusory Feeling Of Knowing In Self-Action Perception, Jonathan Brent Fonville Apr 2011

Illusory Feeling Of Knowing In Self-Action Perception, Jonathan Brent Fonville

Electronic Theses and Dissertations

The perceptual illusion known as "The Illusion of Authorship" has received much attention in recent years. It reflects a false belief that one has willed or authoered an event to occur, when in actuality it was simply coincidence or chance. Previous research has focused on motor movements and the participant's perception of their movement. Researchers have failed to expand on this illusion and apply it to other cognitive processes, such as knowledge, metacognition, memory, etc. Two experiments were conducted using an action dynamics approach, by collecting arm movement trajectories with the Nintendo Wii remote. It was predicted that (1) arm …


Goal Orientation And Ability: Interactive Effects On Self-Efficacy, Performance, And Knowledge, Bradford S. Bell, Steve W.J. Kozlowski Apr 2011

Goal Orientation And Ability: Interactive Effects On Self-Efficacy, Performance, And Knowledge, Bradford S. Bell, Steve W.J. Kozlowski

Bradford S Bell

This study examined the direct relationship of goal orientation – and the interaction of goal orientation and cognitive ability -- with self-efficacy, performance, and knowledge in a learning context. The current paper argues that whether a particular type of goal orientation is adaptive or not adaptive depends on individuals' cognitive ability. Results indicated that the direct associations of learning and performance orientations were consistent with previous research. Learning orientation was positively related to self-efficacy, performance, and knowledge, while performance orientation was negatively related to only one outcome, performance. The interactions between goal orientation and ability also supported several hypotheses. As …


Cognitive Relatives Yet Moral Strangers?, Judith Benz-Scharzberg, Andrew Knight Apr 2011

Cognitive Relatives Yet Moral Strangers?, Judith Benz-Scharzberg, Andrew Knight

Animal Welfare Collection

This article provides an empirically based, interdisciplinary approach to the following two questions: Do animals possess behavioral and cognitive characteristics such as culture, language, and a theory of mind? And if so, what are the implications, when long-standing criteria used to justify differences in moral consideration between humans and animals are no longer considered indisputable? One basic implication is that the psychological needs of captive animals should be adequately catered for. However, for species such as great apes and dolphins with whom we share major characteristics of personhood, welfare considerations alone may not suffice, and consideration of basic rights may …


Response To An Abnormal Ovarian Cancer-Screening Test Result: Test Of The Social Cognitive Processing And Cognitive Social Health Information Processing Models, Michael A. Andrykowski, Edward J. Pavlik Apr 2011

Response To An Abnormal Ovarian Cancer-Screening Test Result: Test Of The Social Cognitive Processing And Cognitive Social Health Information Processing Models, Michael A. Andrykowski, Edward J. Pavlik

Behavioral Science Faculty Publications

All cancer screening tests produce a proportion of abnormal results requiring follow up. Consequently, the cancer-screening setting is a natural laboratory for examining psychological and behavioural response to a threatening health-related event. This study tested hypotheses derived from the social cognitive processing and cognitive-social health information processing models in trying to understand response to an abnormal ovarian cancer (OC) screening test result. Women (n = 278) receiving an abnormal screening test result a mean of 7 weeks earlier were assessed prior to a repeat screening test intended to clarify their previous abnormal result. Measures of disposition (optimism, informational coping style), …


A Fresh Look At Decision Making In International Investment Choices: Firm International Coherence And Home-Host Country Relatedness, Sokol Celo Apr 2011

A Fresh Look At Decision Making In International Investment Choices: Firm International Coherence And Home-Host Country Relatedness, Sokol Celo

FIU Electronic Theses and Dissertations

Understanding how decisions for international investments are made and how this affects the overall pattern of investments and firm’s performance is of particular importance both in strategy and international business research. This dissertation introduced first home-host country relatedness (HHCR) as the degree to which countries are efficiently combined within the investment portfolios of firms. It theorized and demonstrated that HHCR will vary with the motivation for investments along at least two key dimensions: the nature of foreign investments and the connectedness of potential host countries to the rest of the world.

Drawing on cognitive psychology and decision-making research, it developed …


Mind Perception: Real But Not Artificial Faces Sustain Neural Activity Beyond The N170/Vpp, Thalia Wheatley, Anna Weinberg, Christine Looser, Tim Moran, Greg Hajcak Mar 2011

Mind Perception: Real But Not Artificial Faces Sustain Neural Activity Beyond The N170/Vpp, Thalia Wheatley, Anna Weinberg, Christine Looser, Tim Moran, Greg Hajcak

Dartmouth Scholarship

Faces are visual objects that hold special significance as the icons of other minds. Previous researchers using event-related potentials (ERPs) have found that faces are uniquely associated with an increased N170/vertex positive potential (VPP) and a more sustained frontal positivity. Here, we examined the processing of faces as objects vs. faces as cues to minds by contrasting images of faces possessing minds (human faces), faces lacking minds (doll faces), and non-face objects (i.e., clocks). Although both doll and human faces were associated with an increased N170/VPP from 175–200 ms following stimulus onset, only human faces were associated with a sustained …


Common And Distinct Mechanisms Of Cognitive Flexibility In Prefrontal Cortex, Chobok Kim, Nathan F. Johnson, Sara E. Cilles, Brian T. Gold Mar 2011

Common And Distinct Mechanisms Of Cognitive Flexibility In Prefrontal Cortex, Chobok Kim, Nathan F. Johnson, Sara E. Cilles, Brian T. Gold

Neuroscience Faculty Publications

The human ability to flexibly alternate between tasks represents a central component of cognitive control. Neuroimaging studies have linked task switching with a diverse set of prefrontal cortex (PFC) regions, but the contributions of these regions to various forms of cognitive flexibility remain largely unknown. Here, subjects underwent functional brain imaging while they completed a paradigm that selectively induced stimulus, response, or cognitive set switches in the context of a single task decision performed on a common set of stimuli. Behavioral results indicated comparable reaction time costs associated with each switch type. Domain-general task-switching activation was observed in the inferior …