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It’S Time For A New Low-Dose-Radiation Risk Assessment Paradigm—One That Acknowledges Hormesis, Bobby R Scott
It’S Time For A New Low-Dose-Radiation Risk Assessment Paradigm—One That Acknowledges Hormesis, Bobby R Scott
Dose-Response: An International Journal
The current system of radiation protection for humans is based on the linear-nothreshold (LNT) risk-assessment paradigm. Perceived harm to irradiated nuclear workers and the public is mainly reflected through calculated hypothetical increased cancers. The LNT-based system of protection employs easy-to-implement measures of radiation exposure. Such measures include the equivalent dose (a biological-damage-potential-weighted measure) and the effective dose (equivalent dose multiplied by a tissue-specific relative sensitivity factor for stochastic effects). These weighted doses have special units such as the sievert (Sv) and millisievert (mSv, one thousandth of a sievert). Radiation-induced harm is controlled via enforcing exposure limits expressed as effective dose. …
Low-Dose-Radiation Stimulated Natural Chemical And Biological Protection Against Lung Cancer, Bobby R Scott
Low-Dose-Radiation Stimulated Natural Chemical And Biological Protection Against Lung Cancer, Bobby R Scott
Dose-Response: An International Journal
Research is being conducted world-wide related to chemoprevention of future lung cancer among smokers. The fact that low doses and dose rates of some sparsely ionizing forms of radiation (e.g., x rays, gamma rays, and beta radiation) stimulate transient natural chemical and biological protection against cancer in high-risk individuals is little known. The cancer preventative properties relate to radiation adaptive response (radiation hormesis) and involve stimulated protective biological signaling (a mild stress response). The biological processes associated with the protective signaling are now better understood and include: increased availability of efficient DNA double-strand break repair (p53-related and in competition with …